Schedule Update - effective 1 May 2003 (text extract)

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PHARMAC

Pharmaceutical Management Agency

New Zealand Pharmaceutical Schedule

UPDATE

Effective 1 May 2003

Contents

Summary of PHARMAC decisions effective 1 May 2003 ................................ 3 Citalopram tablets ........................................................................................ 4 Dipyridamole long-acting tablets and capsules 150 mg ................................ 4 Delisting Condoms with spermicide .............................................................. 4 Asthma Campaign - update .......................................................................... 4 Stat dispensing proposal ............................................................................... 6 Possible decisions for implementation 1 June 2003 ...................................... 6 Tender News ................................................................................................. 7 Sole Subsidised Supply products cumulative to May 2003 ............................ 8 New Listings ............................................................................................... 15 Changes to Restrictions ............................................................................... 16 Changes to Subsidy and Manufacturer’s Price ............................................ 18 Changes to Sole Subsidised Supply ............................................................. 19 Delisted Items ............................................................................................. 20 Items to be Delisted .................................................................................... 21 Section H changes ...................................................................................... 22 Index ........................................................................................................... 23

Summary of PHARMAC decisions

EFFECTIVE 1 MAY 2003

New listing (page 15) • Glyceryl trinitrate oral pump spray 400 mcg per dose (Nitrolingual Pumpspray) 250 dose OP • Citalopram hydrobromide tab 20 mg (Celapram) – Additional subsidy available by endorsement • Econazole nitrate pessaries 150 mg with applicators (Pevaryl Ovules)

Changes to restrictions (pages 16-17) • Dipyridamole long acting capsules 150 mg (Persantin PL) and tablets 150 mg (Pytazen SR). Special Authority required to access subsidy • Citalopram tablets 20 mg (Celapram and Cipramil) – subsidy by endorsement reduced to $10.00 per 28 tablets

Changes to sole subsidised supply (page 8-14) • Refer to bold entries in the Sole Subsidised Supply table

Decreased subsidy (page 18-19) • Atorvastatin tab 10 mg, 20 mg and 40 mg (Lipitor) • Fluphenazine decanoate inj 100 mg per ml, 1ml (Baxter and Modecate)

Increased subsidy (page 18-19) • Compound hydroxybenzoate solution (David Craig)

Citalopram tablets

A new brand of citalopram tablets 20mg is listed on the Pharmaceutical Schedule from 1 May 2003. Celapram supplied by Pacific Pharmaceuticals will be listed at the current subsidy of $1.58 per 28 tablets. Additional subsidy by endorsement to fully fund Celapram will be available for patients who fit the endorsement criteria outlined on page 17 of this Update. Celapram is to be listed at an ex-manufacturer price of $10.00 per 28 tablets. As a result of this listing the additional subsidy available by endorsement for citalopram tablets (Celapram and Cipramil) has been reduced to $10.00 per 28 tablets. Thus patients prescribed and dispensed the Cipramil brand of citalopram, even with an endorsement, may be required to pay a manufacturer’s surcharge from 1 May 2003.

Dipyridamole long-acting tablets and capsules 150 mg

As a result of the 2001/2002 tender, from 1 May 2003 a current Special Authority approval will be necessary to access the subsidy to dipyridamole long-acting tablets (Pytazen SR) and capsules (Persantin PL) 150mg. Patients prescribed and dispensed Persantin PL may also incur a manufacturer’s surcharge as the manufacturer price is higher than the level of subsidy. Persantin PL will be delisted from the Pharmaceutical Schedule 1 July 2003.

Delisting Condoms with spermicide

Condoms with spermicide (Durex Extra Confidence, Lifestyles Spermicidal and Shield Gold) are to be delisted from the Pharmaceutical Schedule effective 1 November 2003. Until that time there will be no change to the subsidy for these products. Condoms without spermicide and condoms extra strength will continue to be listed on the Pharmaceutical Schedule for the foreseeable future.

Asthma Campaign - update

Asthma Fundamentals training programme The Asthma Fundamentals training programme is now open for enrolment. This programme is subsidised as part of the Asthma Campaign for nurses, community workers and pharmacists. The programme is customised to specific health professional groups. For further information: • nurses and community workers should contact the Asthma and Respiratory Foundation of New Zealand phone (04) 499 4592. • pharmacists should contact the College of Pharmacists phone (04) 802 0030.

All decisions related to news items are effective from 1 May unless otherwise indicated 4

Asthma Campaign media promotion A media campaign including press and radio advertising started on 12 April 2003. Additional patient resource kits were distributed to pharmacies and surgeries on 10 April 2003. Further patient resource kits can be ordered by completing the order form below and sending it to Atlantis Marketing Ltd.

All decisions related to news items are effective from 1 May unless otherwise indicated 5

Stat dispensing proposal

PHARMAC is currently consulting on a proposal to change the way many medicines are dispensed by pharmacies. Under the proposal, about 70 percent of all subsidised dispensings could be picked up by the patient in one three-monthly lot. The remaining 30 percent would continue to be dispensed monthly. A proposed list of medicines that would be dispensed in one three-monthly lot was issued as part of the consultation process. Clinical advice was sought in the compilation of this list which excludes restricted and high cost medicines. The consultation letter and proposed list of medicines to be dispensed in one three-monthly lot is available on our website www.pharmac.govt.nz or by phoning PHARMAC on 0800 66 00 50. The PHARMAC Board is to consider the proposal at its May 2003 meeting and, if approved, the proposed change would be implemented on 1 July 2003.

Looking forward

This section is designed to alert both pharmacists and prescribers to possible future changes. It may assist pharmacists to manage stock levels and keep prescribers up-to-date with proposals to change the Pharmaceutical Schedule. Proposals under consideration The following areas of health care funding are currently under consideration. The PHARMAC Board will be reviewing these proposals, and the decisions taken will be published in future Updates. The dates represented below are the earliest date that these proposals may be implemented. Possible decisions for implementation 1 June 2003 • Fluticasone 250 mcg per dose (Flixotide metered dose inhaler, accuhaler and diskhaler) and budesonide 400 mcg per dose (Pulmicort Turbuhaler) – Special Authority • Omeprazole cap 20 mg (Probitor) – new listing Possible decisions for implementation 1 July 2003 • Implementation of stat dispensing proposal

All decisions related to news items are effective from 1 May unless otherwise indicated 6

Tender News

Sole Subsidised Supply Changes

Chemical Name Presentation; Pack size Sole Subsidised Supply brand (and supplier) Date of Sole Brands affected by Subsidised Supply reference pricing and delisting

Amoxycillin clavulanate Amoxycillin clavulanate

Tab amoxycillin 500 mg with potassium clavulanate 125 mg; 20 tabs Grans for oral liquid amoxycillin 125 mg with potassium clavulanate 31.25 mg per 5 ml; 100 ml Grans for oral liquid amoxycillin 250 mg with potassium clavulanate 62.5 mg per 5 ml; 100 ml 500 mg tabs; 100 tabs 2 mg tabs; 100 tabs Inj 12.5 mg per 0.5 ml; 5 inj Inj 25 mg per ml; 5 inj

Augmentin (GSK) 1 June 2003

Synermox

Augmentin (GSK) 1 June 2003

Synermox

Amoxycillin clavulanate

Augmentin (GSK) 1 June 2003

Synermox

Clonazepam Clonazepam Fluphenazine Decanoate Fluphenazine Decanoate

Paxam (Pacific) Paxam (Pacific) Modecate (Bristol-Meyer) Modecate (Bristol-Meyer)

1 June 2003 1 June 2003 1 June 2003 1 June 2003

Rivotril Rivotril Baxter Baxter

All decisions related to news items are effective from 1 May unless otherwise indicated 7

Sole Subsidised Supply products cumulative to March 2003

Sole Subsidised Supply Products – cumulative to May 2003

Generic Name

Acipimox Acitretin Aciclovir

Presentation

Cap 250 mg Cap 10 mg & 25 mg Tab 200 mg Tab 400 mg & 800 mg Tab dispersible 200 mg, 400 mg & 800 mg Cream Tab 100 mg & 300 mg Oral liquid 1 mg per ml Tab 5 mg with hydrochlorothiazide 50 mg Tab 10 mg Tab 25 mg Tab 50 mg Cap 250 mg & 500 mg Grans for oral liq 125 mg per 5 ml & 250 mg per 5 ml Inj 250 mg Inj 500 mg Inj 1 g Oral drops 125 mg per 1.25 ml Inj 10 mg per ml, 1 ml Tab 50 mg & 100 mg Inj 400 mg 1 ml Inj 600 mg 1 ml Inj 1200 mg 1 ml Eye drops 0.5% Eye drops 1.0% Tab 10 mg Metered aqueous nasal spray, 50 mg per dose & 100 mg per dose Tab 16 mg Oint 0.1%, 30 g & 100 g Crm 0.1%, 30 g & 100 g Eye drops 0.5% Tab 200 mg Suppos 10 mg Tab 2.5 mg Tab 10 mg Metered aqueous nasal spray, 50 mg per dose & 100 mg per dose Tab 5 mg Tab 10 mg Tab 12.5 mg, 25 mg b& 50 mg

Brand Name Expiry Date*

Olbetam Neotigason Apo-Aciclovir Alpha-Aciclovir Acicvir AFT Progout Biomed Amizide Amitrip Amitrip Amitrip Ospamox Ospamox Ospamox Ibiamox Ibiamox Ibiamox Ospamox Paediatric Drops Baxter Loten AstraZeneca AstraZeneca AstraZeneca Atropt Atropt Pacifen Alanase Aqueous Vergo Beta Ointment Beta Cream Apo-Betaxolol Fibalip Fleet Alpha-Bromocriptine Alpha-Bromocriptine Butacort Aqueous Pacific Buspirone Pacific Buspirone Captohexal 2004 2004 2003

Aqueous Cream Allopurinol Amiloride Amiloride with hydrochlorothiazide Amitriptyline

2005 2003 2005 2003 2005

Amoxycillin

2003

2005

Apomorphine hydrochloride Atenolol Atropine sulphate

2005 2003 2005

Baclofen Beclomethasone dipropionate Betahistine dihydrochloride Betamethasone valerate Betaxolol hydrochloride Bezafibrate Bisacodyl Bromocriptine mesylate Budesonide Buspirone hydrochloride Captopril

2003 2003 2003 2005 2004 2005 2004 2005 2003 2004 2004

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 8

Sole Subsidised Supply Products – cumulative to May 2003

Generic Name

Cefaclor monohydrate Cefamandole nafate Ceftriaxone sodium Cefuroxime sodium Celiprolol Cephalexin monohydrate

Presentation

Brand Name Expiry Date*

2004 2005 2005 2005 2004 2005

Cephazolin sodium Cetirizine hydrochloride Charcoal Clomipramine hydrochloride Chloramphenicol Chlorothiazide Ciprofloxacin

Clindamycin hydrochloride Clindamycin phosphate Clobetasol propionate

Clomipramine hydrochloride Clonidine Clonidine hydrochloride Clotrimazole

Colestipol hydrochloride Co-Trimoxazole

Cyclizine lactate Cyclophosphamide Cyproterone acetate Cyproterone acetate with ethinyloestradiol

Cap 250 mg Clorotir Grans for oral liq 125 mg per 5 ml Clorotir Inj 1 g Mandol Inj 500 mg Novartis Inj 1 g Novartis Inj 750 mg Zinacef Tab 200 mg Celol Tab 500 mg Keflex Cap 250 mg Keflex Grans for oral liquid 125 mg per 5 ml Keflex Grans for oral liquid 250 mg per 5 ml Keflex Inj 500 mg Novartis Inj 1 g Novartis Tab 10 mg Razene 50 g per 300 ml oral liquids Carbosorb Tab 10 mg Clopress Eye drops 0.5% Chlorsig Eye oint 1% Chlorsig Oral liq 50 mg per ml Biomed Tab 250 mg Cipflox Tab 500 mg Cipflox Tab 750 mg Cipflox Cap 150 mg Dalacin C Inj 150 mg per ml Dalacin C Crm 0.05% Dermol Oint 0.05% Dermol Scalp app 0.05% Dermol Tab 25 mg Clopress Tab 150 mg Catapres Tab 25 mg Dixarit Vaginal crm 1% with applicators Clocreme Vaginal crm 2% with applicators Clotrimaderm 2% Pessaries 100 mg with applicator Clotrihexal Pessary 500 mg with applicator Clotrihexal Crm 1% Clocreme Sachets 5 g Colestid Tab Trimethoprim 80 mg and Trisul sulphamethoxazole 400 mg Oral liq sugar-free trimethoprim 40 mg Trisul and sulphamethoxazole 200 mg per 5 ml Inj 50 mg per ml, 1 ml Valoid Tab 50 mg Cycloblastin Tab 50 mg Siterone Tab 2 mg with ethinyloestradiol Estelle 35 35 mg and 7 inert tabs

2005 2005 2005 2005 2005 2005 2005

2005 2005 2003 2005 2003 2005 2005 2004

2005 2004 2005 2005 2004 2005 2003 2004

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 9

Sole Subsidised Supply Products – cumulative to May 2003

Generic Name

Danazol Danthron with poloxamer

Presentation

Cap 100 mg Cap 200 mg Oral liq 25 mg with poloxamer 200 mg per 5 ml Oral liq 75 mg with poloxamer 1g per 5 ml Inj 500 mg per 10 ml vial Oral liq 1 mg per ml Range of sizes Tab 5 mg & 10 mg Tab 10 mg Tab 2.5 mg with 25 mg atropine sulphate Tab 30 mg & 60 mg Cap long-acting 120 mg Tab 50 mg Tab 120 mg Oral drops 10% Enema conc 18% Suppository 100 mg with bisacodyl 10 mg Tab 50 mg with total sennosides 8 mg Tab 2 mg & 4 mg Tab 100 mg Ointment Inj 500 mg per ml, 1 ml Tab 500 mg Grans for oral liquid 200 mg per 5 ml Grans for oral liquid 400 mg per 5 ml Tab 400 mg Tab 500 mg Tab 200 mg Cap 50 mg & 100 mg Cap 250 mg & 500 mg Inj 250 mg, 500 mg & 1 g Inj 500 mg per 10 ml Inj 500 mg per 20 ml Tab dispersible 20 mg Cap 20 mg Tab 5 mg 50 mg per ml oral liquid Tab 40 mg Tab 500 mg

Brand Name Expiry Date*

D-Zol D-Zol Conthram Conthram Forte Desferal Biomed Ortho All-flex, Ortho Coil Pro-Pam Merbentyl Diastop Dilzem Dilzem SR Coloxyl Coloxyl Coloxyl Oral Drops Coloxyl Coloxyl Laxsol Dosan Doxine AFT Baxter Eromycin E-Mycin E-Mycin E-Mycin Femulen Etidrate Vepesid Staphlex Flucloxin Baxter Baxter Fluox Fluox Apo-Folic Acid Biomed Diurin 40 Diurin 2004 2005 2005 2003 2005 2005 2004 2005 2005 2004

Desferrioxamine mesylate Dexamethasone Diaphragm Diazepam Dicyclomine hydrochloride Diphenoxylate hydrochloride with atropine sulphate Diltiazem hydrochloride Docusate sodium

Docusate sodium with bisacodyl Docusate sodium with sennosides Doxazosin mesylate Doxycycline hydrochloride Emulsifying Ointment BP Ergometrine maleate Erythromycin estolate Erythromycin ethyl succinate

2005 2004 2004 2003 2005 2005 2004 2005

Ethynodiol diacetate Etidronate disodium Etoposide Flucloxacillin sodium Fluorouracil sodium Fluoxetine hydrochloride Folic acid Frusemide

2005 2003 2004 2003 2004 2004 2004 2003 2005 2003

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 10

Sole Subsidised Supply Products – cumulative to May 2003

Generic Name

Gentamicin sulphate Glibenclamide Gliclazide Glipizide Glyceryl trinitrate Haloperidol decanoate Heparinised saline Hydrocortisone Hydrocortisone with cinchocaine

Presentation

Inj 40 mg per ml, 2 ml Tab 2.5 mg Tab 5 mg Tab 80 mg Tab 5 mg TDDS 5 mg & TDDS 10 mg Inj 50 mg per ml, 1 ml Inj 100 mg per ml, 1 ml Inj 10 iu per ml, 5 ml Inj 50 mg per ml, 2 ml Powder; 25 g Oint 5 mg with cinchocaine hydrochloride 5 mg per g Suppos 5 mg with cinchocaine hydrochloride 5 mg per g Crm 1% with miconazole nitrate 2% Lotn 1% with wool fat hydrous 3% and mineral oil Cap 500 mg Eye drops 0.5% Eye drops 1% Eye drops 0.3% Tab 200 mg Nebuliser soln 250 mg per ml, 1 ml Nebuliser soln 500 mg per 2 ml, 2 ml Aqueous nasal spray, 0.03% Tab 2.5 mg Cap 25 mg Cap 50 mg Cap long-acting 75 mg Suppos 100 mg Tab 20 mg Tab long-acting 60 mg Oral liq 10 g per 15 ml Cap 2 mg Tab 10 mg Tab 1 mg & 2.5 mg Inj 49.3% Inj 150 mg per ml, 1 ml syringe Tab 100 mg Tab 160 mg Tab 10 mg Tab 500 mg & 850 mg

Brand Name Expiry Date*

Pharmacia Gliben Gliben Apo-Gliclazide Minidiab Nitroderm TTS Haldol Haldol Concentrate AstraZeneca Solu-Cortef m-Hydrocortisone Proctosedyl Proctosedyl Micreme H DP Lotn HC Hydrea Methopt Methopt Forte Poly-Tears I-Profen Ipra 250 Ipra 500 Atrovent Nasal Aqueous Naplin Rheumacin Rheumacin Rheumacin Arthrexin Ismo 20 Duride Lactulose Dicap Lora-tabs Lorapam Baxter Depo-Provera Provera HD Megace K Thrombin Metomin 2004 2003 2004 2003 2005 2005 2004 2005 2003 2005 2005 2005 2005 2003 2003 2004 2004 2003 2005 2004 2005 2004 2005 2003 2005 2005 2005 2005 2004 2005 2005 2003 2005 2004

Hydrocortisone with miconazole Hydrocortisone with wool fat and mineral oil Hydroxyurea Hypromellose

Ibuprofen Ipratropium bromide

Indapamide Indomethacin

Isosorbide mononitrate Lactulose Loperamide hydrochloride Loratadine Lorazepam Magnesium sulphate Medroxyprogesterone acetate Megestrol acetate Menadione sodium Metformin hydrochoride

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 11

Sole Subsidised Supply Products – cumulative to May 2003

Generic Name

Methotrexate

Presentation

Brand Name Expiry Date*

Baxter Baxter Baxter Baxter Methoblastin Methoblastin Prodopa Rubifen Medrol Medrol Depo-Medrol Depo-Medrol with lidocaine Solu Medrol Solu Medrol Solu Medrol Solu Medrol AstraZeneca Paramax Daktarin Micreme Hypnovel Hypnovel Cytotec RA Morph RA Morph RA Morph RA Morph Baxter Baxter Apo-Nadolol Naphcon Forte Naxen Naxen Naprosyn SR Naprosyn SR Synflex Synflex Apo-Nicotinic Acid Nyefax Retard Noriday Primolut N Norpress 2004

Inj 5 mg per 2 ml vial Inj 20 mg per 2 ml vial Inj 50 mg per 2 ml vial Inj 100 mg per 4 ml vial Tab 10 mg Tab 2.5 mg Methyldopa Tab 125 mg, 250 mg & 500 mg Methylphenidate hydrochloride Tab 10 mg Methylprednisolone Tab 4 mg Tab 100 mg Methylprednisolone acetate Inj 40 mg per ml, 1 ml Methylprednisolone Inj 40 mg per ml, acetate with lignocaine with lignocaine 1 ml Methylprednisolone sodium Inj 40 mg per ml, 1 ml succinate Inj 62.5 mg per ml, 2 ml Inj 500 mg Inj 1 g Metoclopramide hydrochloride Inj 5 mg per ml, 2 ml Metoclopramide hydrochloride Tab 5 mg with 500 mg paracetamol with paracetamol Miconazole Oral gel 20 mg per g Miconazole nitrate Crm 2% Midazolam Inj 1 mg per ml, 5 ml Inj 5 mg per ml, 3 ml Misoprostol Tab 200 mg Morphine hydrochloride Oral liq 1 mg per ml Oral liq 2 mg per ml Oral liq 5 mg per ml Oral liq 10 mg per ml Morphine tartrate Inj 80 mg per ml, 1.5 ml Inj 80 mg per ml 5 ml Nadolol Tab 40 mg & 80 mg Naphazoline hydrochloride Eye drops 0.1% Naproxen Tab 250 mg Tab 500 mg Tab long-acting 750 mg Tab long-acting 1,000 mg Naproxen sodium Tab 275 mg Tab 550 mg Nicotinic acid Tab 25 mg, 50 mg, 100 mg & 500 mg Nifedipine Tab long-acting 20 mg Norethisterone Tab 350 mg Tab 5 mg Nortriptyline hydrochloride Tab 10 mg

2005 2003 2003 2005 2005 2005 2005

2005 2005 2004 2005 2005 2005 2005

2005 2004 2005 2005

2005 2004 2003 2005 2005

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 12

Sole Subsidised Supply Products – cumulative to May 2003

Generic Name

Nortriptyline Nystatin Oily phenol Olsalazine Ornidazole Pamidronate disodium Paracetamol

Presentation

Tab 25 mg Oral liq 100,000 u per ml Inj 5%, 5 ml Cap 250 mg Tab 500 mg Tab 500 mg Inj 30 mg per 10 ml Tab 500 mg Suppos 125 mg Suppos 250 mg Tab 0.25 mg Tab 1 mg Grans for oral liquid benzathine 125 mg per 5 ml Grans for oral liquid benzathine 250 mg per 5 ml Eye drops 0.5% Eye drops 1% Eye drops 2% Eye drops 3% Eye drops 4% Eye drops 6% Tab 5 mg Tab dispersible 10 mg & 20 mg Inj 75 mg per ml, 10 ml Inj 150 mg per ml, 10 ml Tab 1 mg, 2 mg & 5 mg Tab 1 mg Tab 2.5 mg Tab 5 mg Tab 20 mg Cassette Inj 1.5 mega u Tab 5 mg Tab 200 mg Tab 300 mg Nebuliser soln, 1 mg per ml, 2.5 ml Nebuliser soln, 2 mg per ml, 2.5 ml Nebuliser soln, 2.5 mg with ipratropium bromide 0.5 mg per 2.5 ml vial, 2.5 ml Tab 5 mg 16% enema with 8% sodium phosphate

Brand Name Expiry Date*

Norpress Mycostatin Baxter Dipentum Dipentum Tiberal Pamisol Baxter Pacimol Panadol Panadol Permax Permax AFT AFT Pilopt Pilopt Pilopt Pilopt Pilopt Pilopt Pindol Piram-D AstraZeneca AstraZeneca Hyprosin Apo-Prednisone Apo-Prednisone Apo-Prednisone Apo-Prednisone MDS Quickcard Cilicaine Antinaus Q 200 Q 300 Ventolin Nebules Ventolin Nebules Duolin 2005 2005 2005 2005 2005 2004 2005 2005 2005 2005 2004

Pergolide Phenoxymethylpenicillin (Penicillin V)

Pilocarpine

Pindolol Piroxicam Potassium chloride Prazosin hydrochloride Prednisone

2004 2003 2005 2004 2005

Pregnancy Tests– HCG Urine Procaine penicillin Prochlorperazine Quinine sulphate Salbutamol Salbutamol with ipratropium bromide Selegiline hydrochloride Sodium acid phosphate

2005 2005 2004 2003 2004 2004

Selgene Fleet

2003 2005

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 13

Sole Subsidised Supply Products – cumulative to May 2003

Generic Name

Sodium chloride Spironolactone Sulphacetamide sodium Sulphasalazine Tamoxifen citrate Tar with triethanolamine lauryl sulphate and fluorescein Temazepam Testosterone cypionate Timolol maleate Tranexamic acid Triazolam Triamcinolone acetonide Triamcinolone acetonide with gramicidin, neomycin and nystatin

Presentation

Inj 0.9% 5 ml, 10 ml & 20 ml Tab 25 mg & 100 mg Oral liquid 5 mg per ml Eye drops 10% Tab 500 mg Tab EC 500 mg Tab 10 mg & 20 mg Soln 2.3% with triethanolamine lauryl sulphate and fluorescein sodium Cap 20 mg Cap 10 mg Inj long-acting 100 mg per ml, 10 ml Eye drops 0.25% & 0.5% Tab 500 mg Tab 0.125 mg Dental Paste USP 0.1% Oint 1 mg with nystatin 100,000 u, neomycin sulphate 2.5 mg and gramicidin 250 mg per g Crm 1 mg with nystatin 100,000 u, neomycin sulphate 2.5 mg and gramicidin 250 mg per g Tab 50 mg with hydrochlorothiazide 25 mg Tab 300 mg Cap 25 mg Cap 50 mg Crm 10% Cap 125 mg & 250 mg Inj 50 mg per ml, 10 ml Tab 40 mg & 80 mg Tab long-acting 240 mg Tab long-acting 120 mg Tab (BPC cap strength) Tab, strong, BPC Purified for inj 5 ml, 10 ml & 20 ml Ointment BP Tab 7.5 mg

Brand Name Expiry Date*

Pharmacia Spirotone Biomed Acetopt Salazopyrin Salazopyrin-EN Genox Pinetarsol 2004 2003 2005 2005 2005 2003 2005

Euhypnos Euhypnos Depo Testosterone Apo-Timop Cyklokapron Halcion Oracort Viaderm KC Ointment Viaderm KC Cream Triamizide TMP Tripress Tripress Nutraplus Vancocin Vancocin Verpamil Verpamil SR Verpamil SR Healtheries Multivitamin tablets Apo-B-Complex Pharmacia Sigma Imovane

2005 2005 2005 2004 2004 2005 2005 2005

Triamterene with hydrochlorothiazide Trimethoprim Trimipramine maleate Urea Vancomycin hydrochloride Verapamil hydrochloride Verapamil hydrochloride Vitamins Vitamin B complex Water Zinc and castor oil Zopiclone May changes are in bold type

2003 2005 2005 2005 2004 2003 2005 2004 2003 2004 2005 2005

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 14

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s Price) $ Per

Brand or Generic Mnfr fully subsidised

New Listings

Effective 1 May 2003

GLYCERYL TRINITRATE Oral pump spray 400 mg per dose .............................................. 8.74 250 dose OP Nitrolingual Pumpspray

ECONAZOLE NITRATE Pessaries 150 mg with applicators ............................................. 2.75 (9.71)

3 Pevaryl Ovules

120 CITALOPRAM HYDROBROMIDE - Additional subsidy by endorsement available Tab 20 mg ................................................................................... 1.58 28 (10.00)

Celapram

Additional subsidy by endorsement for: Citalopram tab 20 mg x 28 (Celapram) up to $10.00 is available for patients who: • were taking moclobemide or nefazodone on 1 December 1999 or citalopram on 1 February 2000; or paroxetine hydrochloride on 1 February 2001; or • have previously responded to treatment with moclobemide or nefazodone or citalopram or paroxetine hydrochloride; or • have had a trial of fluoxetine and have to discontinue due to: - inability to tolerate the drug due to side effects; or - failed to respond to an adequate dose and duration of treatment; or • have contraindications to fluoxetine (eg pre-existing significant levels of nausea, breastfeeding, potential drug interactions). The prescription must be endorsed accordingly. We recommend that the words used to indicate eligibility are “certified condition” however these particular words are not a requirement.”

L Three

months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

“IMM” Interchangeable Multi-source Medicines

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s Price) $ Per

Brand or Generic Mnfr fully subsidised

Changes to Restrictions

Effective 1 May 2003

41 DIPYRIDAMOLE Tab 25 mg - Special Authority ..................................................... 0.21 (9.95) 100 Persantin

Additional Subsidy by Special Authority: a) Approval to fully fund dipyridamole tablets 25 mg, long-acting tablets and capsules is available in the following circumstances: - Patients with prosthetic heart valves - as an adjunct to oral anticoagulation for prophylaxis of thromboembolism (applications only from cardiothoracic surgeons, cardiologists and general physicians); or - Patients after coronary artery vein bypass graft - as an adjunct to aspirin or as monotherapy for patients who are aspirin intolerant as defined below (applications only from cardiothoracic surgeons, cardiologists and general physicians); or - Patients who continue to have transient ischaemic episodes despite aspirin therapy or have transient ischaemic episodes and are aspirin intolerant as defined below (applications only from neurologists, neurosurgeons, cardiologists, vascular surgeons and general physicians); b) Approvals are valid indefinitely; c) Aspirin intolerant patients are defined as those with aspirin induced asthma, urticaria, or anaphylaxis, or those with significant aspirin induced bleeding, excluding bruising; d) Prescriptions with a valid Special Authority (CHEM) number will be reimbursed the manufacturer’s price identified in the Pharmaceutical Schedule.

41 DIPYRIDAMOLE Tab long-acting 150 mg - Special Authority .............................. 11.95 Cap long-acting 150 mg - Special Authority .............................. 11.95 (22.39) Pytazen SRIMM Persantin PLIMM

60 60

Additional Subsidy by Special Authority - Retail pharmacy: a) Approvals to fund dipyridamole tablets, long-acting tablets and capsules 150 mg is available in the following circumstances: - Patients with prosthetic heart valves - as an adjunct to oral anticoagulation for prophylaxis of thromboembolism (applications only from cardiothoracic surgeons, cardiologists and general physicians); or - Patients after coronary artery vein bypass graft - as an adjunct to aspirin or as monotherapy for patients who are aspirin intolerant as defined below (applications only from cardiothoracic surgeons, cardiologists and general physicians); or - Patients who continue to have transient ischaemic episodes despite aspirin therapy or have transient ischaemic episodes and are aspirin intolerant as defined below (applications only from neurologists, neurosurgeons, cardiologists, vascular surgeons and general physicians); b) Approvals are valid indefinitely; c) Aspirin intolerant patients are defined as those with aspirin induced asthma, urticaria, or anaphylaxis, or those with significant aspirin induced bleeding, excluding bruising; d) Prescriptions with a valid Special Authority (Chem) number will be reimbursed the manufacturer’s price subsidy identified in the Pharmaceutical Schedule.

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

‡ safety cap reimbursed Sole Subsidised Supplier

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s Price) $ Per

Brand or Generic Mnfr fully subsidised

Changes to Restrictions - effective 1 May 2003 (continued)

120 CITALOPRAM HYDROBROMIDE - Additional subsidy by endorsement available Tab 20 mg ................................................................................... 1.58 28 (10.00) (31.45)

Celapram Cipramil

Additional subsidy by endorsement for: Moclobemide tab 150 mg x 100 (Aurorix) up to $32.90 Moclobemide tab 300 mg x 60 (Aurorix) up to $39.48 Nefazodone tab 100 mg x 56 (Serzone) up to $20.16 Nefazodone tab 200 mg x 56 (Serzone) up to $40.32 Citalopram tab 20 mg x 28 (Cipramil and Celapram) up to $31.45 $10.00 Paroxetine hydrochloride tab 20 mg x 30 (Aropax) up to $35.02 is available for patients who: • were taking moclobemide or nefazodone on 1 December 1999 or citalopram on 1 February 2000; or paroxetine hydrochloride on 1 February 2001; or • have previously responded to treatment with moclobemide or nefazodone or citalopram or paroxetine hydrochloride; or • have had a trial of fluoxetine and have to discontinue due to: - inability to tolerate the drug due to side effects; or - failed to respond to an adequate dose and duration of treatment; or • have contraindications to fluoxetine (eg pre-existing significant levels of nausea, breastfeeding, potential drug interactions). The prescription must be endorsed accordingly. We recommend that the words used to indicate eligibility are “certified condition” however these particular words are not a requirement.”

L Three

months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

“IMM” Interchangeable Multi-source Medicines

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s Price) $ Per

Brand or Generic Mnfr fully subsidised

Changes to Subsidy and Manufacturer’s Price

45 ATORVASTATIN - Special Authority (Øsubsidy) Tab 10 mg ................................................................................. 23.94 Tab 20 mg ................................................................................. 34.89 Tab 40 mg ................................................................................. 48.39 TOLNAFTATE - Not in combination (≠price) Crm 1% ....................................................................................... 1.00 (8.60) Soln 1% ...................................................................................... 4.36 (6.87) BETAMETHASONE DIPROPIONATE (≠price) Crm 0.05% .................................................................................. 2.96 (6.28) Crm 0.05% .................................................................................. 8.97 (16.69) Crm 0.05% in propylene glycol base ........................................... 4.33 (12.57) Oint 0.05% .................................................................................. 2.96 (5.92) Oint 0.05% .................................................................................. 8.97 (15.55) Oint 0.05% in propylene glycol base ........................................... 4.33 (12.57) 30 30 30 Lipitor Lipitor Lipitor

20 g OP Tinaderm 10 ml OP Tinaderm

15 g OP Diprosone 50 g OP Diprosone 30 g OP Diprosone OV 15 g OP Diprosone 50 g OP Diprosone 30 g OP Diprosone OV

BETAMETHASONE DIPROPIONATE WITH CLOTRIMAZOLE - Only on a prescription (≠price) Crm 0.05% with clotrimazole 1% ................................................ 4.90 15 g OP (8.19) Lotricomb BETAMETHASONE DIPROPIONATE WITH SALICYLIC ACID - Only on a prescription (≠price) Oint 0.05% with salicylic acid 3% ............................................... 8.10 30 g OP (11.28) Diprosalic Lotn 0.05% with salicylic acid 2% ............................................... 9.74 50 ml OP (14.21) Diprosalic DIPHEMANIL METHYLSULPHATE (≠price)

a) Subsidised only if prescribed for an amputee with an artificial limb, or for a paraplegic patient; and b) On a prescription endorsed accordingly.

Powder 2% .................................................................................. 6.81 (11.77) 73 TAR WITH CADE OIL (≠price) Bath emulsion 7.5% coal tar, 2.5% cade oil, 7.5% compound ..... 9.70 (29.60) 50 g OP Prantal

350 ml Polytar Emollient

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

‡ safety cap reimbursed Sole Subsidised Supplier

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s Price) $ Per

Brand or Generic Mnfr fully subsidised

Changes to Subsidy and Manufacturer’s Price– effective 1 May 2003 (continued)

73 BETAMETHASONE DIPROPIONATE (≠price) Scalp lotn 0.05% ....................................................................... 12.29 (22.91) 100 ml OP Diprosone

115 BUPIVACAINE HYDROCHLORIDE - Special Authority (≠price) Inj 0.5%, 4 ml .......................................................................... 23.32 (29.95) 129 FLUPHENAZINE DECANOATE - Retail pharmacy-specialist (Øsubsidy) Inj 100 mg per ml, 1 ml - Available on a PSO .......................... 154.50 (168.00) 144 AZATADINE MALEATE (≠price) Tab 1 mg ..................................................................................... 6.94 (16.90) 145 DEXTROCHLORPHENIRAMINE MALEATE (≠price) Tab 2 mg ..................................................................................... 2.52 (9.08) Tab long-acting 6 mg .................................................................. 6.75 (14.28)

5 Marcain Isobaric

Modecate Baxter

50 Zadine

50 Polaramine 50 Polaramine Repetab

145 LORATADINE (≠price) Oral liq 1 mg per ml .................................................................... 4.00 (9.85) 169 COMPOUND HYDROXYBENZOATE (≠subsidy) Solution .................................................................................... 21.50

100 ml Claratyne

100 ml

David Craig

(Only in extemporaneously compounded oral mixtures)

Changes to Sole Subsidised Supply

Effective 1 May 2003

For the list of new Sole Subsidised Supply products effective 1 May 2003 refer to the bold entries in the cumulative Sole Subsidised Supply table pages 8–14.

L Three

months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

“IMM” Interchangeable Multi-source Medicines

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s Price) $ Per

Brand or Generic Mnfr fully subsidised

Delisted Items

Effective 1 May 2003

31 GLICLAZIDE Tab 80 mg ................................................................................. 39.08 (78.80) CLOBETASONE BUTYRATE Oint 0.05% .................................................................................. 5.38 (5.91) Oint 0.05% ................................................................................ 16.13 (18.33) 500 Diamicron

30 g OP Eumovate 100 g OP Eumovate

TRIAMCINOLONE ACETONIDE WITH GRAMICIDIN, NEOMYCIN AND NYSTATIN Only on a prescription Crm 1 mg with nystatin 100,000 u, neomycin sulphate 2.5 mg and gramicidin 250 mg per g .......................................... 3.49 15 g OP (6.09) Oint 1 mg with nystatin 100,000 u, neomycin sulphate 2.5 mg and gramicidin 250 mg per g .......................................... 3.49 15 g OP (6.09) GROWTH HORMONE BIOSYNTHETIC HUMAN - Special Authority Inj 12 iu per vial ...................................................................... 291.00 Cartridge 12 iu per vial ............................................................ 291.00 Cartridge 24 iu per vial ............................................................ 582.00

Kenacomb

1 1 1

Norditropin Norditropin Penset 12 Norditropin Penset 24

CIPROFLOXACIN - Retail pharmacy-specialist Tab 250 mg ............................................................................... 11.42 (48.16) Tab 500 mg ............................................................................... 20.44 (86.68) Tab 750 mg ............................................................................... 28.87 (138.16)

28 Ciproxin 28 Ciproxin 28 Ciproxin

107 DIDANOSINE (ddI) - Special Authority Tab 25 mg reduced mass .......................................................... 46.02 Tab 100 mg reduced mass ..................................................... 184.08 110 IBUPROFEN - Special Authority available Tab 200 mg ................................................................................. 2.07 (2.90) 110 NAPROXEN - Special Authority available Tab 250 mg ............................................................................... 26.50 Tab EC 250 mg ........................................................................... 6.36 Tab 500 mg ............................................................................... 53.00 Tab EC 500 mg ........................................................................... 6.36 Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

60 60

Videx Videx

100 Panafen

500 120 500 60

Naprosyn IMM Naprosyn Enteric Naprosyn IMM Naprosyn EntericIMM ‡ safety cap reimbursed Sole Subsidised Supplier

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s Price) $ Per

Brand or Generic Mnfr fully subsidised

Delisted Items – effective 1 May 2003 (continued)

119 PHENELZINE SULPHATE Tab 15 mg ................................................................................. 14.90 50 Nardil Note: Link Phamaceuticals (09) 358 7146 is supplying Nardil tablets under Section 29. 119 TRIMIPRAMINE MALEATE Tab 25 mg ................................................................................... 3.19 (6.58) Cap 50 mg ................................................................................ 12.00 (23.00) 146 BECLOMETHASONE DIPROPIONATE Aerosol inhaler, 100 mg per dose .............................................. 25.00 183 ISOMIL ............................................................................................ 2.89 (7.20)

50 Surmontil 100 Surmontil

200 dose OP Respocort 100-S 400 g OP

Items to be Delisted

Effective 1 August 2003

129 FLUPHENAZINE DECANOATE - Retail pharmacy-specialist Inj 100 mg per ml, 1 ml - Available on a PSO .......................... 154.50 (168.00) 5 Baxter

Effective 1 November 2003

43 DEXTROSE WITH ELECTROLYTES Soln with electrolytes .................................................................. 3.44 (3.89) DISOPYRAMIDE PHOSPHATE Tab long-acting 250 mg ............................................................ 71.60 (86.64) VERAPAMIL HYDROCHLORIDE Tab 120 mg ............................................................................... 25.32 500 ml OP Pedialyte

100 Rythmodan Retard

100

Civicor

GLYCERYL TRINITRATE Oral pump spray 400 mg per dose .............................................. 6.99 200 dose OP Nitrolingual Pumpspray Note: Nitrolingual Pumpspray 250 dose OP listed fully subsidised 1 May 2003 CONDOMS WITH SPERMICIDE - Available on a PSO .................... 28.56 144 Durex Extra Confidence Lifestyles Spermicidal Shield Gold

L Three

months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

“IMM” Interchangeable Multi-source Medicines

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s Price) $ Per

Brand or Generic Mnfr fully subsidised

Items to be delisted – effective 1 November 2003 (continued)

78 ETHINYLOESTRADIOL WITH NORGESTREL - Available on a PSO Tab 50 mg with norgestrel 500 mg ............................................... 3.15 (4.73) ECONAZOLE NITRATE Pessaries 150 mg with applicators ............................................. 2.75 (9.71)

21 Ovral

3 Gyno-Pevaryl

118 AMOXAPINE Tab 25 mg ................................................................................. 17.50 175 ENSURE POWDER (banana, chocolate) Special Authority – Hospital pharmacy [HP3] ............................. 6.13 (8.60)

100

Asendin

400 g OP

Section H changes effective 1 May 2003

Changes to Part II – Pharmaceuticals under National Contracts

Contracted Pharmaceutical Description Brand Price ($) Per (ex man. excl. GST) DV Limit DV Limit applies from DV Pharmaceutical

CITALOPRAM HYDROBROMIDE Tab 20 mg

Celapram 10.00

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

‡ safety cap reimbursed Sole Subsidised Supplier

Index

Pharmaceuticals and brands

Amoxapine .......................................................... 22 Asendin ............................................................... 22 Atorvastatin ........................................................ 18 Azatadine maleate ............................................... 19

Kenacomb ........................................................... 20

Lifestyles Spermicidal ......................................... 21 Lipitor ................................................................. 18 Loratadine ........................................................... 19 Lotricomb ........................................................... 18

Beclomethasone dipropionate ............................. 21 Betamethasone dipropionate ........................ 18, 19 Betamethasone dipropionate with clotrimazole ..... 18 Betamethasone dipropionate with salicylic acid .... 18 Bupivacaine hydrochloride .................................. 19

Marcain Isobaric ................................................. 19 Modecate ............................................................ 19

Naprosyn ............................................................ 20 Naprosyn Enteric ................................................ 20 Naproxen ............................................................ 20 Nardil .................................................................. 21 Nitrolingual Pumpspray ................................ 15, 21 Norditropin .......................................................... 20 Norditropin Penset 12 ......................................... 20 Norditropin Penset 24 ......................................... 20

Celapram ............................................... 15, 17, 22 Cipramil .............................................................. 17 Ciprofloxacin ....................................................... 20 Ciproxin .............................................................. 20 Citalopram Hydrobromide .................... 15, 17, 22 Civicor ................................................................ 21 Claratyne ............................................................ 19 Clobetasone butyrate .......................................... 20 Compound Hydroxybenzoate .............................. 19 Condoms with spermicide .................................. 21

Ovral ................................................................... 22

ddI ...................................................................... 20 Dextrochlorpheniramine Maleate ......................... 19 Dextrose with electrolytes ................................... 21 Diamicron ........................................................... 20 Didanosine .......................................................... 20 Diphemanil Methylsulphate ................................. 18 Diprosalic ............................................................ 18 Diprosone .................................................... 18, 19 Diprosone OV ...................................................... 18 Dipyridamole ....................................................... 16 Disopyramide Phosphate .................................... 21 Durex Extra Confidence ....................................... 21

Panafen ............................................................... 20 Pedialyte ............................................................. 21 Persantin ............................................................. 16 Persantin PL ........................................................ 16 Pevaryl Ovules .................................................... 15 Phenelzine sulphate ............................................ 21 Polaramine .......................................................... 19 Polaramine Repetab ............................................ 19 Polytar Emollient ................................................. 18 Prantal ................................................................ 18 Pytazen SR ......................................................... 16

Respocort 100-S ................................................ 21 Rythmodan Retard .............................................. 21

Econazole Nitrate ......................................... 15, 22 Ensure Powder .................................................... 22 Ethinyloestradiol with norgestrel ......................... 22 Eumovate ............................................................ 20

Shield Gold ......................................................... 21 Surmontil ............................................................ 21

Fluphenazine Decanoate ............................... 19, 21

Tar with cade oil .................................................. 18 Tinaderm ............................................................ 18 Tolnaftate ............................................................ 18 Triamcinolone acetonide with gramicidin, neomycin and nystatin ...................................... 20 Trimipramine maleate .......................................... 21

Gliclazide ............................................................ 20 Glyceryl Trinitrate ......................................... 15, 21 Growth hormone biosynthetic human ................. 20 Gyno-Pevaryl ...................................................... 22

Ibuprofen ............................................................ 20 Isomil .................................................................. 21

Verapamil Hydrochloride ..................................... 21 Videx ................................................................... 20

Zadine ................................................................. 19

While care has been taken in compiling this Update, Pharmaceutical Management Agency takes no responsibility for any errors or omissions and shall not be liable to any person for any damages or loss arising out of reliance by that person for any purpose on any of the contents of this Update. Errors and omissions brought to the attention of Pharmaceutical Management Agency will be corrected if necessary by an erratum or otherwise in the next edition of the Update. Pharmaceutical Management Agency Level 1 Old Bank Chambers 98 Customhouse Quay PO Box 10 254 Wellington New Zealand Telephone 64 4 460 4990 Facsimile 64 4 460 4995 Freephone information line (9 am – 4 pm weekdays) 0800 66 00 50 http://www.pharmac.govt.nz

Metadata

Title

Schedule Update - effective 1 May 2003

Abstract

Page 1

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