Schedule Update - effective 1 November 2007 (text extract)

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UPDATE

New Zealand Pharmaceutical Schedule

Effective 1 November 2007

Cumulative for September, October and November 2007 Section H cumulative for August, September, October and November 2007

Contents

Summary of PHARMAC decisions .................................................................. 3 Betaloc CR still fully funded ........................................................................... 4 Ritalin SR Special Access Subsidy ................................................................... 5 Named Specialists for antiretrovirals ............................................................. 6 Delay in Implementation of Sole Subdised Supply of aspirin 300 mg dispersible tablets ......................................................................................... 6 Clarification of General Rule – Specialist Prescription .................................... 7 Tender News .................................................................................................. 7 Looking Forward ........................................................................................... 7 Sole Subsidised Supply products cumulative to November 2007 .................. 8 New Listings ................................................................................................ 17 Changes to Restrictions ............................................................................... 20 Changes to Subsidy and Manufacturer’s Price............................................. 25 Changes to General Rules............................................................................ 29 Changes to Section G: Safety Cap Medicines............................................... 30 Changes to Sole Subsidised Supply ............................................................. 30 Delisted Items ............................................................................................. 31 Items to be Delisted .................................................................................... 34 Section H changes to Part II ........................................................................ 37 Section H changes to Part IV ....................................................................... 41 Index ........................................................................................................... 42

Summary of Pharmac decisions

effectIve 1 November 2007 New listing (page 17) • Ranitidine hydrochloride (Peptisoothe) oral liq 150 mg per 10 ml – Only on a prescription – subsidy by endorsement • Ferrous sulphate (Ferodan) oral liq 150 mg per 5 ml, 500 ml • Aspirin (Ethics Aspirin EC) tab 100 mg, 990 pack size • Sodium chloride (Multichem) inj 0.9%, 20 ml • Doxazosin mesylate (Apo-Doxazosin) tab 2 mg and 4 mg • Ritonavir (Norvir) oral liq 80 mg per ml, 90 ml OP – Special Authority – Hospital pharmacy [HP1] • Methadone hydrochloride (AFT) inj 10 mg per ml, 1 ml – only on a controlled drug form – no patient co-payment payable • Quetiapine (Quetapel) tab 25 mg, 100 mg, 200 mg and 300 mg • Acetylcysteine (Hospira) inj 200 mg per ml, 10 ml – Hospital pharmacy [HP1] – Specialist Increased subsidy (page 25) • Diazepam (Stesolid) rectal tubes 5 mg and 10 mg Decreased subsidy (page 25) • Povidone iodine (Riodine) antiseptic soln 10%, 500 ml • Azithromycin (Zithromax) tab 500 mg • Methadone hydrochloride (Pallidone) tab 5 mg

Pharmaceutical Schedule - Update News

Betaloc CR still fully funded

Betaloc CR, metoprolol succinate, continues to be fully funded by endorsement for all patients who are currently taking it.

AstraZeneca has raised the price of Betaloc CR. PHARMAC followed suit by raising the subsidy by endorsement for some patients. This decision represents an additional $4 million per year of spending. We recognise that the endorsement requirement adds to clinicians’ paperwork, however our feeling is that endorsing prescriptions is a preferable option to other choices we could have made at this time. An additional $4 million per year is not an insignificant amount of money, and will limit our ability to make other medicine investment decisions. Our view was that maintaining full subsidy for existing patients, through the endorsement mechanism, was better than the 200,000 or so Betaloc patients having to pay manufacturer’s surcharges, or changing to fully funded medicines. This would have meant considerable disruption for patients and more work for clinicians and pharmacists. Compared to the possibility of patients changing medicines, the endorsement option minimises the impact of these funding changes on patients. The good news is the endorsement requirement is an interim move while we await the outcome of Medsafe’s assessment of a generic form of metoprolol succinate. We will be reviewing the endorsement and subsidy on Betaloc CR.

PHARMAC already has an agreement to fund a generic, once it is registered by Medsafe. The generic metoprolol succinate would cost 53% less than Betaloc CR and could lead to savings of about $13 million per year which could be used to fund other medicine or healthcare. In order to have Betaloc CR fully subsidised the patient must have been prescribed Betaloc CR before 1 October, or have had a myocardial infarction, and the prescription must be endorsed accordingly. Pharmacists are not eligible to endorse prescriptions. All other patients who are prescribed Betaloc CR by their doctor will need to pay a small manufacturer’s surcharge.

The decision is also being supported by information developed by BPACNZ. This information has been distributed to all clinicians and pharmacists and is also available on PHARMAC’s website (www. pharmac.govt.nz).

Pharmaceutical Schedule - Update News

Ritalin SR Special Access Subsidy

PHARMAC has agreed to fund Ritalin SR for some patients. Funding is available for patients who have experienced serious adverse reactions when switching from Ritalin SR to Rubifen SR, the recently funded brand of 20 mg sustained-release methylphenidate hydrochloride. This action is being taken in response to concerns raised by Medsafe and the Centre for Adverse Reactions Monitoring (CARM). Some patients have reported serious adverse reactions associated with switching from Ritalin SR to Rubifen SR, including aggressive or threatening behaviour and, less commonly, unusual psychiatric events. These adverse reactions were reported in less than 2% of patients and did not have any obvious cause. Most of the adverse reactions reported to CARM occurred within a few days of the brand switch. These types of severe behavioural side effects have been reported overseas for all brands of methylphenidate, including Ritalin. Most people who developed these side effects never exhibited this type of behaviour before being started on methylphenidate. Medsafe remains satisfied that the two brands are bioequivalent, and that no safety issues have been identified for patients currently stabilised on Rubifen SR. However, Medsafe is seeking further information from the supplier of Rubifen SR, AFT Pharmaceuticals, to try and determine whether any further action is necessary.

While Medsafe conducts its investigations into Rubifen SR, PHARMAC intends to make Ritalin SR available, on application, to those patients with documented evidence of serious adverse events associated with the change from Ritalin SR to Rubifen SR. As PHARMAC cannot guarantee the ongoing long-term supply of Ritalin SR we would urge prescribers to consider this mechanism only in cases where all other alternative treatment options, including dose adjustment of Rubifen SR, have been unsuccessful. The Ritalin SR Special Access form is available on the PHARMAC website at www.pharmac. govt.nz. Amongst other information, applicants are required to provide details of their nominated pharmacy. A nominated pharmacy is a pharmacy that has agreed to source and stock Ritalin SR for the specified patient. Please note that if the patient moves and/or needs to collect the medication from a different pharmacy, or the pharmacy decides to source Ritalin SR with a different pharmacode, PHARMAC must be informed or the medication will not be subsidised. An estimated yearly cost of treatment as quoted by the pharmacy is also required (Cost, Brand, Source). Pharmacies are encouraged to source Ritalin SR from Novartis NZ Ltd in the first instance but if New Zealand stocks are no longer available Ritalin SR may be sourced from overseas under Section 29 of the Medicines Act 1981.

Pharmaceutical Schedule - Update News

Named Specialists for antiretrovirals

Below is a list of currently approved Named Specialists that the Ministry of Health has approved to prescribe HIV antiretroviral agents in New Zealand.

Auckland Dr Simon Briggs Dr Rob Ellis-Pegler Dr Rick Franklin Dr Rupert Handy Dr David Holland Dr Joan Ingram Prof Diana Lennon Dr Nicky Perkins Dr Stephen Ritchie Dr Sally Roberts Dr Simon Rowley Dr Mark Thomas Dr Leslie Voss Dr Liz Wilson HAMILTON Dr Graham Mills Dr Jane Morgan TAURANGA Dr Neil Graham NAPIER Dr Richard Meech

PALMERSTON NORTH Dr Anne Robertson NELSON Dr Richard Everts WELLINGTON Dr Tim Blackmore Dr Nigel Raymond Dr Richard Steele CHRISTCHURCH Dr Stephen Chambers Dr Maud Meates-Dennis Dr Sarah Metcalf Dr Alan Pithie DUNEDIN Dr Leo Celi Dr Deborah Williams

Delay in Implementation of Sole Subsidised Supply of aspirin 300 mg dispersible tablets

In the Tender notification fax dated 27 September 2007, PHARMAC notified of the tender for aspirin tab disp 300 mg that has been awarded to Multichem for its 100 tablet pack size of Ethics Aspirin. There will be a delay in the listing of the new pack size. This was due to be listed 1 November 2007 but will now be listed at a later date in 2008. We will advise of further details in a future Update.

Clarification of General Rule – Specialist Prescription

The definitions of Retail Pharmacy – Specialist Prescription and Hospital Pharmacy – Specialist Prescription have been amended in the Pharmaceutical Schedule. This is to help avoid any misinterpretation of who is eligible to sign the prescription. For the purposes of Retail Pharmacy – Specialist and Hospital Pharmacy – Specialist restrictions, DHB hospital prescriptions are considered to meet the criteria for subsidy. For Retail Pharmacy – Specialist Prescription and Hospital Pharmacy – Specialist Prescription restrictions, the person signing the prescription must be a Specialist. The rule amendment does not change the intention of the Retail and Hospital Pharmacy – Specialist Prescription definition but, helps to clarify it. Please refer to page 29 for full details.

tender News

Sole Subsidised Supply changes – effective 1 December 2007

Chemical Name Cetomacrogol Hydrocortisone butyrate Malathion Oxycodone hydrochloride Oxycodone hydrochloride Oxycodone hydrochloride Phenylephrine hydrochloride Presentation; Pack size Crm BP; 500 g Scalp lotn 0.1%; 100 ml OP Liq 0.5%; 00 ml Inj 10 mg per ml, 1 ml; 5 inj Inj 10 mg per ml, ml; 5 inj Oral liq 5 mg per 5 ml; 50 ml Eye drops 0.1%; 15 ml OP Sole Subsidised Supply brand (and supplier) PSM (API) Locoid (CSL) Derbac-M (SSL) OxyNorm (MundiPharma) OxyNorm (MundiPharma) OxyNorm (MundiPharma) Prefrin (Allergan)

Looking forward

This section is designed to alert both pharmacists and prescribers to possible future changes. It may assist pharmacists to manage stock levels and keep prescribers up-to-date with proposals to change the Pharmaceutical Schedule. Possible decisions for implementation 1 December 2007 • Oxaliplatin inj 50 mg and 100 mg (Eloxatin) and inj 1 mg for ECP (Baxter) – amended Special Authority criteria • Paclitaxel inj 30 mg, 100 mg (Taxol), 150 mg, 300 mg (Paclitaxel Ebewe) and inj 1 mg for ECP (Baxter) – removal of Special Authority restriction • Saquinavir (Invirase) film-coated tablet 500 mg – new listing under existing Special Authority criteria • Vinorelbine inj 10 mg per ml, 1 ml and 5 ml (Vinorelbine Ebewe) and inj 1 mg for ECP (Baxter) – amended Special Authority criteria

Sole Subsidised Supply Products – cumulative to November 2007

Generic Name

Acetazolamide Acipimox Acitretin Allopurinol Amitriptyline Amlodipine Apomorphine hydrochloride Amoxycillin

Presentation

Tab 50 mg Cap 50 mg Cap 10 mg & 5 mg Tab 100 mg & 00 mg Tab 10 mg, 5 mg & 50 mg Tab 5 mg & 10 mg Inj 10 mg per ml, 1 ml Cap 50 mg & 500 mg Grans for oral liq 15 mg per 5 ml Grans for oral liq 50 mg per 5 ml Inj 50 mg, 500 mg & 1 g Device Cream Tab 100 mg Tab 50 mg & 100 mg Inj 600 µg, 1 ml Inj 100 µg, 1 ml Eye drops 1% Metered aqueous nasal spray 50 µg Metered aqueous nasal spray 100 µg Scalp app 0.1% Crm 0.1% Oint 0.1% Tab 00 mg Tab 5 mg Eye drops 0.% Tab .5 mg & 10 mg Inj 0.5%, 4 ml Inj 0.5%, % glucose, 4 ml Lotion BP Crm, aqueous, BP Cap 0.5 µg & 0.5 µg Tab dispersible .5 g Tab 1.5 g Tab 1.5 g Inj 50 mg Cap 50 mg Grans for oral liq 15 mg per 5 ml Inj 500 mg & 1 g

Brand Name Expiry Date*

Diamox Olbetam Neotigason Progout Amitrip Calvasc Mayne Apo-Amoxi Ranbaxy Amoxicillin Ranbaxy Amoxicillin Ibiamox Ortho Multichem Apo-Ascorbic Acid Loten AstraZeneca AstraZeneca Atropt Alanase Alanase Beta Scalp Beta Cream Beta Ointment Fibalip Lax-Tab AFT Alpha-Bromocriptine Marcain Isobaric Marcain Heavy ABM ABM Calcitriol-AFT Calci-Tab Effervescent Calci-Tab 500 Calci-Tab 600 Calcium Folinate Ebewe Ranbaxy Cefaclor Ranbaxy Cefaclor m-Cefazolin 00 00 00 00 00 00 009 010 009 00 00 00 009 009 009 00 009 009 00 00 010 00 00 010 009 009 00

Applicator Aqueous cream Ascorbic acid Atenolol Atropine sulphate

Beclomethasone dipropionate Betamethasone valerate

Bezafibrate Bisacodyl Brimonidine tartrate Bromocriptine mesylate Bupivicaine hydrochloride Calamine Calcitriol Calcium carbonate

Calcium folinate Cefaclor monohydrate Cefazolin sodium

00 010 00

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated.

Sole Subsidised Supply Products – cumulative to November 2007

Generic Name

Ceftriaxone sodium Cetirizine hydrochloride Chloramphenicol Chlorhexidine gluconate

Presentation

Inj 500 mg & 1 g Oral liq 1 mg per ml Tab 10 mg Eye drops 0.5% Eye oint 1% Handrub 1% with ethanol 0% Mouthwash 0.% Soln 4% Tab 5 mg Tab 50 mg, 500 mg & 50 mg Grans for oral liq 15 mg per 5 ml Cap hydrochloride 150 mg Inj phosphate 150 mg per ml, 4 ml Crm 0.05% Scalp app 0.05% Oint 0.05% Tab 500 µg & mg TDDS .5 mg, 100 µg per day TDDS 5 mg, 00 µg per day TDDS .5 mg, 00 µg per day Tab 5 µg Tab 150 µg Inj 150 µg per ml, 1 ml Vaginal crm 1% with applicator(s) Crm 1% Tab 500 µg Powder for soln for oral use Oral liq sugar-free trimethoprim 40 mg and sulphamethoxazole 00 mg per 5 ml Tab trimethoprim 0 mg and sulphamethoxazole 400 mg Tab 50 mg Inj 50 mg per ml, 1 ml Tab 50 mg Tab 50 mg Cap 5 mg & 50 mg Inj 500 mg Nasal spray 10 µg per dose Inj 4 mg per ml, 1 ml Inj 4 mg per ml, ml

Brand Name Expiry Date*

AFT Allerid C Razene Chlorsig Chlorsig Orion Orion Orion Hygroton Cipflox Klacid Dalacin C Dermol Dermol Dermol Paxam Catapres-TTS-1 Catapres-TTS- Catapres-TTS- Dixarit Catapres Catapres Clomazol Clomazol Colgout Enerlyte Trisul 00 00 009 009 00 009 00 010 00 009 00 00 00

Chlorthalidone Ciprofloxacin Clarithromycin Clindamycin Clobetasol propionate

Clonazepam Clonidine

Clonidine hydrochloride

Clotrimazole Colchicine Compound electrolytes Co-trimoxazole

010 00 010 010 00

Cyclizine hydrochloride Cyclizine lactate Cyclophosphamide Cyproterone acetate Dantrolene sodium Desferrioxamine mesylate Desmopressin Dexamethasone sodium phosphate

Nausicalm Valoid (AFT) Cycloblastin Siterone Dantrium Mayne Desmopressin-PH&T Mayne

009 00 010 009 009 010 00 009

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 9

Sole Subsidised Supply Products – cumulative to November 2007

Generic Name

Diaphragm Dicloflenac sodium Didanosine (DDI) Dihydrocodeine tartrate Diphenoxylate hydrochloride with atropine sulphate Dipyridamole Docusate sodium Emulsifying ointment BP Enalapril Ergometrine maleate Ergotamine tartrate with caffeine Erythromycin ethyl succinate Ethambutol hydrochloride Ethinyloestradiol Ethinyloestradiol with norethisterone

Presentation

Range of sizes Tab EC 5 mg & 50 mg Tab long-acting 5 mg & 100 mg Cap 15 mg, 00 mg, 50 mg & 400 mg Tab long-acting 60 mg Tab .5 mg with atropine sulphate 5 µg Tab long-acting 150 mg Tab 50 mg & 10 mg Ointment Tab 5 mg, 10 mg & 0 mg Inj 500 µg per ml, 1 ml Tab 1 mg with caffeine 100 mg Grans for oral liq 00 mg per 5 ml Grans for oral liq 400 mg per 5 ml Tab 400 mg Tab 10 µg Tab 5 µg with norethisterone 500 µg Tab 5 µg with norethisterone 1 mg Tab 5 µg with norethisterone 1 mg and inert tab Tab 5 µg with norethisterone 500 µg and inert tab Cap 50 mg & 100 mg Cap 50 mg & 500 mg Grans for oral liq 15 mg per 5 ml Grans for oral liq 50 mg per 5 ml Cap 50 mg, 150 mg & 00 mg Oint 950 µg, with fluocortolone pivalate 90 µg, and cinchocaine hydrochloride 5 mg per g Suppos 630 µg, with fluocortolone pivalate 610 µg, and cinchocaine hydrochloride 1 mg Eye drops 0.1% Inj 1.5 mg per 0.5 ml, 0.5 ml Inj 5 mg per ml, 1 ml Inj 100 mg per ml, 1 ml

Brand Name Expiry Date*

Ortho All-flex & Ortho Coil Apo-Diclo Apo-Diclo SR Videx EC DHC Continus Diastop Pytazen SR Coloxyl AFT m-Enalapril Mayne Cafergot E-Mycin E-Mycin Myambutol New Zealand Medical and Scientific Brevinor 1 Brevinor 1/1 Brevinor 1/ Norimin Vepesid Staphlex AFT AFT Pacific Ultraproct Ultraproct 00 009 009 00 009 009 00 00 00 00 00 009 009 009 00 00 009 010

Etoposide Flucloxacillin sodium

Fluconazole Fluocortolone caproate with fluocortolone pivalate and cinchocaine

00 010

Fluorometholone Fluphenazine decanoate

Flucon Modecate Modecate Modecate

009 00

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 10

Sole Subsidised Supply Products – cumulative to November 2007

Generic Name

Folic Acid Fusidic acid Gentamicin sulphate Gliclazide Glipizide Haloperidol

Presentation

Tab 0. mg & 5 mg Crm % & Oint % Inj 40 mg per ml, ml Tab 0 mg Tab 5 mg Oral liq mg per ml Tab 500 µg, 1.5 mg & 5 mg Inj 5 mg per ml, 1 ml Inj 50 mg per ml, 1 ml Inj 100 mg per ml, 1 ml Inj 10 iu per ml, 5 ml Tab 5 mg & 0 mg Powder 5 g Rectal foam 10%, CFC-Free Lotn 1% with wool fat hydrous % and mineral oil Tab 10 mg Inj 0 mg Eye drops 0.% Eye drops 0.5% Oral liq 100 mg per 5 ml, 200 ml Tab 00 mg Tab 10 mg & 5 mg Tab .5 mg Cap 5 mg & 50 mg Nebuliser soln, 50 µg per ml, 1 ml Nebuliser soln, 50 µg per ml, ml Aerosol inhaler, 0 µg per dose CFC-free Tab long-acting 60 mg Cap 10 mg Cap 0 mg Cap 100 mg Shampoo % Eye drops 0.5% & 0.5%

Brand Name Expiry Date*

Apo-Folic Acid Foban Pfizer Apo-Gliclazide Minidiab Serenace Serenace Serenace Haldol Haldol Concentrate AstraZeneca Douglas m-Hydrocortisone Colifoam DP Lotn HC Gastrosoothe Buscopan Poly-Tears Methopt Fenpaed I-Profen Tofranil Napamide Rheumacin Ipratripium Steri-Neb Ipratripium Steri-Neb Atrovent Duride Isotane 10 Isotane 0 Sporanox Ketopine Betagan 009 010 009 00 00 010 009 00 009 009 00 009 00 00 00 2010 00 009 009 00 010 00 009 009 010 00 010

Haloperidol decanoate Heparinised saline Hydrocortisone Hydrocortisone acetate Hydrocortisone with wool fat and mineral oil Hyoscine N-butylbromide Hypromellose Ibuprofen Imipramine hydrochloride Indapamide Indomethacin Ipratropium bromide

Isosorbide mononitrate Isotretinoin Itraconazole Ketoconazole Levobunolol

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 11

Sole Subsidised Supply Products – cumulative to November 2007

Generic Name

Levodopa with benserazide

Presentation

Cap 50 mg with benserazide 1.5 mg Tab dispersible 50 mg with benserazide 1.5 mg Cap 100 mg with benserazide 5 mg Cap long-acting 100 mg with benserazide 5 mg Cap 00 mg with benserazide 50 mg Inj 0.5%, 5 ml Inj 1%, 5 ml Inj 1%, 0 ml Crm .5% with prilocaine .5%; 0 g OP Crm .5% with prilocaine .5%; 5 g Tab 5 mg, 10 mg & 0 mg Tab mg Oral liq 1 mg per ml Tab 1 mg & .5 mg Inj 49.% Shampoo 1% Tab 5 mg & 5 mg Tab .5 mg, 5 mg, 10 mg, 100 mg & 00 mg Enema 1 g per 100 ml Powder 1 g Tab .5 mg & 10 mg Inj 100 mg per ml, 5 ml Inj 100 mg per ml, 10 ml Inj 100 mg per ml, 50 ml Tab 15 mg, 50 mg & 500 mg Tab long-acting 0 mg Tab 5 mg & 0 mg Tab 10 mg Tab 4 mg & 100 mg Crm 0.1% and oint 0.1% Inj 40 mg per ml, 1 ml Inj 40 mg per ml with lignocaine 1 ml Inj 40 mg per ml, 1 ml Inj 6.5 mg per ml, 1 ml Inj 500 mg & 1 g Inj 5 mg per ml, ml

Brand Name Expiry Date*

Madopar 6.5 Madopar Dispersible Madopar 15 Madopar HBS Madopar 50 Xylocaine Xylocaine Xylocaine EMLA EMLA Arrow-Lisinopril Nodia Lorapaed Ativan Mayne A-Lices Ludiomil Provera Pentasa AFT Methoblastin Methotrexate Ebewe Methotrexate Ebewe Methotrexate Ebewe Prodopa Rubifen SR Rubifen Rubifen Medrol Advantan Depo-Medrol Depo-Medrol with Lidocaine Solu-Medrol Solu-Medrol Solu-Medrol Pfizer 009 010 010 009 009 010 009 010 009 009 009 00 010 009

Lignocaine hydrochloride

Lignocaine with prilocaine

010

Lisinopril Loperamide hydrochloride Loratadine Lorazepam Magnesium sulphate Maldison Maprotiline hydrochloride Medroxyprogesterone acetate Mesalazine Methadone hydrochloride Methotrexate

Methyldopa Methylphenidate hydrochloride

00 009

Methylprednisolone Methylprednisolone aceponate Methylprednisolone acetate Methylprednisolone acetate with lignocaine Methylprednisolone sodium succinate Metoclopramide hydrochloride

009 009 00 00 009

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 1

Sole Subsidised Supply Products – cumulative to November 2007

Generic Name

Metoprolol tartrate Metyrapone Mexiletine hydrochloride Miconazole nitrate Midodrine Misoprostol Moclobemide Morphine hydrochloride

Presentation

Tab long-acting 00 mg Cap 50 mg Cap 50 mg & 00 mg Crm % Tab .5 mg & 5 mg Tab 00 µg Tab 150 mg & 00 mg Oral liq 1 mg per ml Oral liq mg per ml Oral liq 5 mg per ml Oral liq 10 mg per ml Inj 5 mg per ml, 1 ml Inj 15 mg per ml, 1 ml Cap long-acting 10 mg, 0 mg, 60 mg, 100 mg & 00 mg Tab immediate release 10 mg & 0 mg Inj 0 mg per ml, 1.5 ml & 5 ml Tab 40 mg & 0 mg Tab 50 mg Eye drops 0.1% Tab 50 mg Tab 500 mg Tab long-acting 50 mg Tab long-acting 1000 mg Inj .5 mg per ml, 1 ml Oral suspension 10 mg per ml Tab 50 mg & 500 mg Tab long-acting 0 mg Jelly % Tab 50 µg Tab 5 mg Tab 400 mg Tab 10 mg & 5 mg Cap 500,000 u Tab 500,000 u Vaginal crm 100,000 u per 5 g with applicators Oral liq 100,000 u per ml Tab 4 mg & mg Tab disp 4 mg & mg

Brand Name Expiry Date*

Slow-Lopressor Metopirone Mexitil Multichem Gutron Cytotec Apo-Moclobemide RA-Morph RA-Morph RA-Morph RA-Morph Mayne Mayne m-Eslon Sevredol Mayne Apo-Nadolol ReVia Naphcon Forte Noflam 250 Noflam 500 Naprosyn SR 50 Naprosyn SR 1000 AstraZeneca Viramune Suspension Apo-Nicotinic Acid Nyefax Retard Gynol II Noriday Primolut-N Arrow-Norfloxacin Norpress Nilstat Nilstat Nilstat Nilstat Zofran Zofran Zydis 009 010 010 00 009 00 010 009 009 009 00 009 00 00 00 010 009 00 010 009 009 00 00 009 009 009 009

Morphine sulphate

009

Morphine tartrate Nadolol Naltrexone hydrochloride Naphazoline hydrochloride Naproxen

Neostigmine Nevirapine Nicotinic acid Nifedipine Nonoxynol-9 Norethisterone Norfloxacin Nortriptyline Nystatin

Ondansetron

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 1

Sole Subsidised Supply Products – cumulative to November 2007

Generic Name

Oxytocin

Presentation

Inj 5 iu per ml, 1 ml Inj 10 iu per ml, 1 ml Inj 5 iu with ergometrine maleate 500 µg per ml, 1 ml Inj mg per ml, 5 ml Inj mg per ml, 10 ml Inj 6 mg per ml, 10 ml Tab 500 mg Suppos 15 mg & 50 mg Oral liq 10 mg per 5 ml Oral liq 50 mg per 5 ml Tab 500 mg with mg codeine Eye oint with soft white paraffin Tab 0 mg Tab 0.5 mg & 1 mg Tab 100 mg Cap potassium salt 50 mg Cap potassium salt 500 mg Eye drops 0.5%, 1%, %, 4% & 6% Oral drops 10% Tab long-acting 600 mg Inj 5 mg per ml, 10 ml Inj 150 mg per ml, 10 ml Tab 1 mg, .5 mg, 5 mg & 0 mg Cassette Inj 1.5 mega u Tab 10 mg & 5 mg Tab 50 mg Tab 5 mg, 10 mg & 0 mg Tab 10 mg with hydrochlorothiazide 1.5 mg Tab 0 mg with hydrochlorothiazide 1.5 mg Tab 00 mg Tab 00 mg Tab 150 mg & 00 mg Cap 150 mg Tab 150 mg & 00 mg

Brand Name Expiry Date*

Syntocinon Syntocinon Syntometrine Pamisol Pamisol Pamisol Panadol Panadol Junior Parapaed Six Plus Parapaed Codalgin Laci-Lube Loxamine Permax Pexsig Cilicaine VK Cilicaine VK Pilopt Coloxyl Span-K AstraZeneca AstraZeneca Apo-Prednisone MDS Quick Card Cilicaine Allersoothe Apo-Pyridoxine Accupril Accuretic 10 Accuretic 0 Q 00 Q 00 Arrow Ranitidine Mycobutin Arrow-Roxithromycin 009 00 010 009 009

Pamidronate disodium

Paracetamol

Paracetamol with codeine Paraffin liquid with soft white paraffin Paroxetine hydrochloride Pergolide Perhexiline maleate Phenoxymethylpenicillin (Penicillin V) Pilocarpine Poloxamer Potassium chloride

00 010 010 00 009 010 00 00 009 00 00 009 00 00 009 00 00

Prednisone Pregnancy tests - HCG urine Procaine penicillin Promethazine hydrochloride Pyridoxine hydrochloride Quinapril Quinapril with hydrochlorothiazide

Quinine sulphate Ranitidine hydrochloride Rifabutin Roxithromycin

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 14

Sole Subsidised Supply Products – cumulative to November 2007

Generic Name

Salbutamol

Presentation

Nebuliser soln 1 mg per ml, .5 ml Nebuliser soln mg per ml, .5 ml Oral liq mg per 5 ml Nebuliser soln, .5 mg with ipratropium bromide 0.5 mg Tab 5 mg Inj 0.9%, 5 ml & 10 ml Grans eff 4 g sachets Nasal spray 4% Eye drops % Tab 500 mg Tab EC 500 mg Liq Soln .% with triethanolamine lauryl sulphate and fluorescein sodium Tab 10 mg Tab 50 mg Tab 10 mg Tab 50 mg Crm & Oint 0.0% Dental Paste USP 0.1% Ear drops 1 mg with nystatin 100,000 u, neomycin sulphate .5 mg and gramicidin 50 mcg per g Oint 1 mg with nystatin 100,000 u, neomycin sulphate .5 mg and gramicidin 50 µg per g Tab 15 µg Tab 50 µg Tab 00 mg Cap 5 mg & 50 mg Crm 10% Cap 00 mg Inj 50 mg per ml, 10 ml Tab long-acting 10 mg Inj 1 mg per ml, 1 ml Inj 1 mg per ml, ml Tab (BPC cap strength)

Brand Name Expiry Date*

Asthalin Asthalin Salapin Duolin Apo-Selegiline AstraZeneca Ural Rex Cromolux Salazopyrin Salazopyrin EN Midwest Pinetarsol Normison Apo-Terbinafine Apo-Timol Apo-Thiamine Aristocort Oracort Kenacomb Kenacomb 009 010 009 009 009 010 009 00 009 010 00 00 00 009 009 00 009 00

Salbutamol with ipratropium bromide Selegiline hydrochloride Sodium chloride Sodium citro-tartrate Sodium cromoglycate Sulphasalazine Syrup (pharmaceutical grade) Tar with triethanolamine lauryl sulphate and fluorescein Temazepam Terbinafine Timolol maleate Thiamine hydrochloride Triamcinolone acetonide Triamcinolone acetonide with gramicidin, neomycin and nystatin

Triazolam Trimethoprim Trimipramine maleate Urea Ursodeoxycholic acid Vancomycin hydrochloride Verapamil hydrochloride Vincristine sulphate Vitamins

Hypam Hypam TMP Tripress Nutraplus Actigall Pacific Verpamil SR Mayne Mayne Healtheries

00 00 00 00 00 00 00 009 009

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 15

Sole Subsidised Supply Products – cumulative to November 2007

Generic Name

Vitamin B complex Water Zinc and castor oil Zinc sulphate Zopiclone

Presentation

Tab, strong, BPC Purified for injection 20 ml Oint BP Cap 0 mg Tab .5 mg

Brand Name Expiry Date*

Apo-B-Complex Multichem Multichem Zincaps Apo-Zopiclone 009 009 00 00 00

November changes are in bold type

*Expiry date of the Sole Subsidised Supply period is 30 June of the year indicated. 16

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

New Listings

Effective 1 November 2007

6 RANITIDINE HYDROCHLORIDE – Only on a prescription ❋ Oral liq 150 mg per 10 ml – Subsidy by endorsement ................ .95 00 ml ✔ Peptisoothe Oral liquid is subsidised only for patients: 1) with oesophageal stricture, or ) in terminal care, or ) who are either too young or too old to swallow conventional tablets and the prescription is endorsed accordingly. Note: the cost of treatment with ranitidine oral liquid is higher than that of ranitidine tablets. Following the derestriction of access PHARMAC will be monitoring expenditure on ranitidine oral liquid more closely and may, subject to consultation and PHARMAC Board approval, restrict access again if the expenditure was to grow substantially. FERROUS SULPHATE ❋‡ Oral liq 150 mg per 5 ml ....................................................... 10.0 ASPIRIN ❋ Tab 100 mg ........................................................................... 16. SODIUM CHLORIDE Inj 0.9%, 0 ml ......................................................................... .6 DOXAZOSIN MESYLATE ❋ Tab mg ................................................................................. 4.1 ❋ Tab 4 mg ................................................................................. 6. RITONAVIR – Special Authority see SA09 – Hospital pharmacy [HP1] Oral liq 0 mg per ml ............................................................ 10.9 500 ml 990 0 100 100 90 ml OP ✔ Ferodan ✔ Ethics Aspirin EC ✔ Multichem ✔ Apo-Doxazosin ✔ Apo-Doxazosin ✔ Norvir

44 4 51

95 104

METHADONE HYDROCHLORIDE a) Only on a controlled drug form b) No patient co-payment payable c) Extemporaneously compounded methadone will only be reimbursed at the rate of the cheapest form available (methadone powder, not methadone tablets). d) For methadone hydrochloride oral liquid refer, page 159 ✔ AFT S29 Inj 10 mg per ml, 1 ml ............................................................ 5.00 10 QUETIAPINE Tab 5 mg ............................................................................. 0.6 Tab 100 mg ........................................................................... 41.5 Tab 00 mg ........................................................................... 0. Tab 00 mg ......................................................................... 119.5 ACETYLCYSTEINE – Hospital pharmacy [HP1]-Specialist Inj 00 mg per ml, 10 ml ...................................................... 1.06 (4.50) 90 90 90 90 10 Hospira ✔ Quetapel ✔ Quetapel ✔ Quetapel ✔ Quetapel

160

Effective 1 October 2007

▲

MESALAZINE Suppos 1 g ............................................................................ 50.96 Three months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

✔ Pentasa

❋ Three months or six months, as applicable, dispensed all-at-once

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

New Listings - effective 1 October 2007 (continued)

OMEPRAZOLE ❋ Cap 10 mg ............................................................................... .99 ❋ Cap 0 mg ............................................................................... 4. ❋ Cap 40 mg ............................................................................... 5.01 4 4 LACTULOSE – Only on a prescription ❋ Oral liq 10 g per 15 ml .............................................................. 6.65 ✔ Dr Reddy’s Omeprazole ✔ Dr Reddy’s Omeprazole ✔ Dr Reddy’s Omeprazole ✔ Duphalac

1,000 ml

MACROGOL 50 – Special Authority see SA091 – Retail pharmacy Powder 1.15 g, sachets – not more than 60 sachets per prescription.................................................. 1.14 0 ✔ Movicol ➽ SA0891 Special Authority for Subsidy Initial application by any relevant practitioner. Approvals valid for 6 months where the patient has problematic constipation requiring intervention with a per rectal preparation despite an adequate trial of other oral pharmacotherapies including lactulose where lactulose is not contraindicated. Renewal from any relevant practitioner. Approvals valid for 1 months where the patient is compliant and is continuing to gain benefit from treatment. SIMVASTATIN – See prescribing guideline ❋ Tab 10 mg ............................................................................... .1 ❋ Tab 0 mg ............................................................................... .1 ❋ Tab 40 mg ............................................................................... 4.9 0 0 0 ✔ SimvaRex ✔ SimvaRex ✔ SimvaRex

IBUPROFEN – Additional subsidy by Special Authority see SA091 – Retail pharmacy ❋ Tab 600 mg ............................................................................. 1.60 0 (6.4) CITALOPRAM HYDROBROMIDE ❋ Tab 0 mg ............................................................................... .50 MIDAZOLAM Inj 1 mg per ml, 5 ml .............................................................. 1.65 (14.73) Inj 5 mg per ml, ml .............................................................. 14.00 (19.64) 10

Brufen ✔ Citalopram - Rex

10 11

Pfizer 5 Pfizer

146

BUDESONIDE WITH EFORMOTEROL – Special Authority see SA0 – Retail pharmacy Aerosol inhaler 100 µg with eformoterol fumarate 6 µg ..................................................................... 55.00 10 dose OP ✔ Symbicort Rapihaler Aerosol inhaler 00 µg with eformoterol fumarate 6 µg ..................................................................... 60.00 10 dose OP ✔ Symbicort Rapihaler IPRATROPIUM BROMIDE Aqueous nasal spray, 0.0% .................................................. 1.66 0 ml OP ✔ Apo-Ipravent

14 10

SOYA INFANT FORMULA – Special Authority see SA0604 – Retail pharmacy Powder ..................................................................................... 6.4 900 g OP (19.5)

S6 Soy

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

S29 Unapproved medicine supplied under Section 9 Sole Subsidised Supply ‡ safety cap reimbursed

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

New Listings - effective 17 September 2007

144 LORATADINE ❋ Tab 10 mg ............................................................................... .5 .50 100 0 ✔ Loraclear Hayfever Relief ✔ Loraclear Hayfever Relief

Effective 1 September 2007

6 AZITHROMYCIN – Subsidy by endorsement a) Maximum of tab per prescription b) Available on a PSO c) Subsidised only if prescribed for patients with uncomplicated urethritis or cervicitis proven or presumed to be due to Chlamydia trachomatis and their sexual contacts and prescription or PSO is endorsed accordingly. Tab 500 mg ............................................................................. 9.90 OP ✔ Arrow-Azithromycin METHADONE HYDROCHLORIDE a) Only on a controlled drug form b) No patient co-payment payable c) Extemporaneously compounded methadone will only be reimbursed at the rate of the cheapest form available (methadone powder, not methadone tablets). d) For methadone hydrochloride oral liquid refer, page 159 Tab 5 mg ................................................................................. .10 10 ✔ PSM OXYCODONE HYDROCHLORIDE a) Only on a controlled drug form b) No patient co-payment payable Inj 10 mg per ml, 1 ml ............................................................ 14.40 5 ✔ OxyNorm ✔ OxyNorm Inj 10 mg per ml, ml ............................................................ .0 5 ‡ Oral liq 5 mg per 5 ml ............................................................. 11.0 50 ml ✔ OxyNorm Prescribing Guideline Prescribers should note that oxycodone is significantly more expensive than long-acting morphine sulphate and clinical advice suggests that it is reasonable to consider this as a second-line agent to be used after morphine.

104

106

▲

Three months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

❋ Three months or six months, as applicable, dispensed all-at-once

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to Restrictions

Effective 1 October 2007

5 55 HYDROCORTISONE ACETATE Rectal foam 10 %, CFC-Free (14 applications) ........................ 1.10 1.1 g OP ✔ Colifoam

METOPROLOL SUCCINATE ❋ Tab long-acting .5 mg – Higher subsidy of $6.20 per 30 with Endorsement ........................................... 5.0 (6.0) ❋ Tab long-acting 4.5 mg – Higher subsidy of $7.80 per 30 with Endorsement ........................................... 6.50 (.0) ❋ Tab long-acting 95 mg – Higher subsidy of $13.20 per 30 with Endorsement ....................................... 11.0 (1.0) ❋ Tab long-acting 190 mg – Higher subsidy of $21.00 per 30 with Endorsement ....................................... 0.5 (1.00) Additional subsidy by endorsement is available for patients who: a) were being prescribed metoprolol succinate prior to 1 October 2007; or b) have experienced a myocardial infarction. The prescription must be endorsed accordingly

0 Betaloc CR 0 Betaloc CR 0 Betaloc CR 0 Betaloc CR

Note – Repeats for Betaloc CR tab long-acting will be fully subsidised where the initial dispensing was before 1 October 2007. PHENOXYMETHYLPENICILLIN (PENICILLIN V) Grans for oral liq benzathine 15 mg per 5 ml – Available on a PSO ................................................................ 1.6 Grans for oral liq benzathine 50 mg per 5 ml – Available on a PSO ................................................................ 1.

100 ml 100 ml

✔ AFT ✔ AFT

QUETIAPINE – Subsidy by endorsement Subsidised for: 1) patients presenting with first episode schizophrenia or related psychoses, or manic episodes associated with bipolar disorder; and ) patients suffering from schizophrenia or related psychoses, or manic episodes associated with bipolar disorder, after a trial of an effective dose of risperidone that has been discontinued because of unacceptable side effects or inadequate response. Initial prescription must be written by a relevant specialist. Subsequent prescriptions may be written by a general practitioner. The prescription must be endorsed “certified condition”. Tab 5 mg ............................................................................. 46.0 60 ✔ Seroquel Tab 100 mg ........................................................................... 9.40 60 ✔ Seroquel Tab 00 mg ......................................................................... 15.6 60 ✔ Seroquel Tab 00 mg ......................................................................... 6.1 60 ✔ Seroquel MYCOPHENOLATE MOFETIL – Special Authority see SA0893 09 – Hospital pharmacy [HP] Tab 500 mg ......................................................................... 06.66 50 ✔ Cellcept Cap 50 mg ......................................................................... 06.66 100 ✔ Cellcept Powder for oral liq 1 g per 5 ml – Subsidy by endorsement .... 5.00 165 ml OP ✔ Cellcept Mycophenolate powder for oral liquid is subsidised only for patients unable to swallow tablets and capsules, and when the prescription is endorsed accordingly. continued...

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

Unapproved medicine supplied under Section 9 Sole Subsidised Supply ‡ safety cap reimbursed

S29

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to Restrictions - effective 1 October 2007 (continued)

continued... ➽ SA0893 0798 Special Authority for Subsidy Initial application only from a relevant specialist. Approvals valid without further renewal unless notified for applications meeting the following criteria: Any of the following: 1 Renal transplant recipient; or Heart transplant recipient; or Patient has an organ transplant and has severe tophaceous gout making azathioprine unsuitable. Renewal only from a relevant specialist. Approvals valid without further renewal unless notified where the patient had a previous Special Authority approval and was receiving mycophenolate prior to 1 October 005. 150 150 ACICLOVIR ❋ Eye oint % – Retail pharmacy-Specialist................................. .5 4.5 g OP ✔ Zovirax

CIPROFLOXACIN Eye Drops 0.% – Retail pharmacy-Specialist prescription ...... 1.4 5 ml OP ✔ Ciloxan 1) Specialist must be an ophthalmologist. ) For treatment of bacterial keratitis or severe bacterial conjunctivitis resistant to chloramphenicol. DEXAMETHASONE WITH FRAMYCETIN AND GRAMICIDIN Retail Pharmacy – Specialist when used in the treatment of eye conditions. Ear/Eye drops 500 µg with framycetin sulphate 5 mg and gramicidin 50 µg per ml......................................................... 4.50 ml OP (9.) GENTAMICIN SULPHATE Eye drops 0.% – Retail pharmacy-Specialist........................... 11.40 BETAXOLOL HYDROCHLORIDE – Retail pharmacy-Specialist ❋ Eye drops 0.5% .................................................................... 11.0 ❋ Eye drops 0.5% ........................................................................ .50 DEXAMETHASONE – Retail pharmacy-Specialist ❋ Eye oint 0.1% ........................................................................... 5.6 ❋ Eye drops 0.1 % ....................................................................... 4.50 5 ml OP 5 ml OP 5 ml OP .5 g OP 5 ml OP

150

Sofradex ✔ Genoptic ✔ Betoptic S ✔ Betoptic ✔ Maxidex ✔ Maxidex

150 151

151

DEXAMETHASONE WITH NEOMYCIN AND POLYMYXIN B SULPHATE – Retail pharmacy-Specialist ❋ Eye oint 0.1% with neomycin sulphate 0.5% and polymyxin B sulphate 6,000 u per g ....................................................... 5.9 .5 g OP ✔ Maxitrol ❋ Eye drops 0.1% with neomycin sulphate 0.5% and polymyxin B sulphate 6,000 u per ml ..................................................... 4.50 5 ml OP ✔ Maxitrol DICLOFENAC SODIUM ❋ Eye drops 1 mg per ml – Retail pharmacy-Specialist ................ 1.0 FLUOROMETHOLONE – Retail pharmacy-Specialist ❋ Eye drops 0.1% ........................................................................ 4.0 LEVOBUNOLOL – Retail pharmacy-Specialist ❋ Eye drops 0.5% ...................................................................... .00 ❋ Eye drops 0.5 % ....................................................................... .00 5 ml OP 5 ml OP 5 ml OP 5 ml OP ✔ Voltaren Ophtha ✔ Flucon ✔ Betagan ✔ Betagan

151 151 151

▲

Three months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

❋ Three months or six months, as applicable, dispensed all-at-once

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to Restrictions - effective 1 October 2007 (continued)

151 PREDNISOLONE ACETATE – Retail pharmacy-Specialist ❋ Eye drops 0.1% ...................................................................... 4.50 (.5) ❋ Eye drops 1% ........................................................................... 4.50 (9.44) TOBRAMYCIN Eye oint 0.% – Retail pharmacy-Specialist.............................. 10.45 Eye drops 0.% – Retail pharmacy-Specialist........................... 11.4 BRIMONIDINE TARTRATE – Retail pharmacy-Specialist ❋ Eye Drops 0.% ........................................................................ .95 DORZOLAMIDE HYDROCHLORIDE – Retail pharmacy-Specialist ❋ Eye drops % ........................................................................... 9. (1.95) 5 ml OP Pred Mild 5 ml OP Pred Forte .5 g OP 5 ml OP 5 ml OP 5 ml OP Trusopt ✔ Tobrex ✔ Tobrex ✔ AFT

151

15 15

DORZOLAMIDE HYDROCHLORIDE WITH TIMOLOL MALEATE – Retail pharmacy-Specialist ❋ Eye drops % with timolol maleate 0.5% ................................. 1.50 5 ml OP ✔ Cosopt TIMOLOL MALEATE – Retail pharmacy-Specialist ❋ Eye drops 0.5% ...................................................................... . ❋ Eye drops 0.5%, gel forming ................................................... 5.0 ❋ Eye drops 0.5% ........................................................................ .9 ❋ Eye drops 0.5%, gel forming ..................................................... 5. 5 ml OP .5 ml OP 5 ml OP .5 ml OP ✔ Apo-Timop ✔ Timoptol XE ✔ Apo-Timop ✔ Timoptol XE ✔ Combigan

15 15

BRIMONIDINE TARTRATE WITH TIMOLOL MALEATE – Retail pharmacy-Specialist ▲ Eye drops 0.% with timolol maleate 0.5% .............................. 1.50 5 ml OP

PILOCARPINE ❋ Eye drops % single dose – Special Authority see SA0895 011 – Hospital pharmacy [HP] ....................................................... 1.95 0 dose (.) Minims ➽ SA0895 0121 Special Authority for Subsidy Initial application from any relevant practitioner medical practitioner. Approvals valid for years for applications meeting the following criteria: Either: 1 Patient has to use an unpreserved solution due to an allergy to the preservative; or Patient wears soft contact lenses. Note: Minims for a general practice are considered to be “tools of trade” and are not approved as special authority items. Renewal from any relevant practitioner medical practitioner. Approvals valid for years where the treatment remains appropriate and the patient is benefiting from treatment. FAT ➽ SA0899 0580 Special Authority for Subsidy Initial application — (Inborn errors of metabolism) only from a relevant specialist. Approvals valid for years where the patient has inborn errors of metabolism. Initial application — (Indications other than inborn errors of metabolism) only from a relevant specialist. Approvals valid for 1 year for applications meeting the following criteria: Any of the following: 1 failure to thrive where other high calorie products are inappropriate or inadequate; or continued...

S29 Unapproved medicine supplied under Section 9 Sole Subsidised Supply ‡ safety cap reimbursed

164

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to Restrictions - effective 1 October 2007 (continued)

continued... 2 growth deficiency; or bronchopulmonary dysplasia; or 4 fat malabsorption; or 5 lymphangiectasia; or 6 short bowel syndrome; or infants with necrotising enterocolitis; or biliary atresia. Renewal — (Inborn errors of metabolism) only from a relevant specialist or general practitioner on the recommendation of a relevant specialist. Approvals valid for years for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is benefiting from treatment; and General Practitioners must include the name of the specialist and date contacted. Renewal — (Indications other than inborn errors of metabolism) only from a relevant specialist or general practitioner on the recommendation of a relevant specialist. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is benefiting from treatment; and General Practitioners must include the name of the specialist and date contacted. 16 PAEDIATRIC PRODUCTS ➽ SA0896 0590 Special Authority for Subsidy Initial application only from a relevant specialist. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 infant aged one to eight six years; and Any of the following: .1 any condition causing malabsorption; or . failure to thrive; or . increased nutritional requirements; and Either: .1 The product is to be used as a supplement (maximum 500 ml per day); or . The product is to be used as a complete diet. Renewal only from a relevant specialist or general practitioner on the recommendation of a relevant specialist. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 The treatment remains appropriate and the patient is benefiting from treatment; and Either: .1 The product is to be used as a supplement (maximum 500 ml per day); or . The product is to be used as a complete diet; and General Practitioners must include the name of the specialist and date contacted.

▲

Three months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

❋ Three months or six months, as applicable, dispensed all-at-once

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to Restrictions - effective 1 September 2007

11 ONDANSETRON – Hospital pharmacy [HP] Retail pharmacy-Specialist a) Maximum of 1 tab per prescription; can be waived by Special Authority see SA0887 below b) Maximum of 6 tab per dispensing; can be waived by Special Authority see SA0887 below c) Not more than one prescription per month; can be waived by Special Authority see SA0887 below. Tab 4 mg ............................................................................... 1.1 10 ✔ Zofran Tab disp 4 mg ........................................................................ 1.1 10 ✔ Zofran Zydis Tab mg ............................................................................... .9 0 ✔ Zofran Tab disp mg ........................................................................ 0.4 10 ✔ Zofran Zydis ➽ SA0887 Special Authority for Waiver of Rule Initial application from any relevant practitioner. Approvals valid for 12 months where patient is undergoing prolonged treatment with highly emetogenic chemotherapy and/or highly emetogenic radiation therapy for the treatment of malignancy. Renewal from any relevant practitioner. Renewals valid for 12 months where patient is undergoing prolonged treatment with highly emetogenic chemotherapy and/or highly emetogenic radiation therapy for the treatment of malignancy.

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

S29 Unapproved medicine supplied under Section 9 Sole Subsidised Supply ‡ safety cap reimbursed

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to Subsidy and Manufacturer’s Price

Effective 1 November 2007

65 POVIDONE IODINE (è price) Oint 10% ................................................................................... . (.) a) Maximum of 100 g per prescription b) Only on a prescription POVIDONE IODINE (ê subsidy) Antiseptic soln 10% .................................................................. 6.0 5 g OP Betadine

65 6

500 ml

✔ Riodine

AZITHROMYCIN – Subsidy by endorsement (ê subsidy) a) Maximum of tab per prescription b) Available on a PSO c) Subsidised only if prescribed for patients with uncomplicated urethritis or cervicitis proven or presumed to be due to Chlamydia trachomatis and their sexual contacts and prescription or PSO is endorsed accordingly. Tab 500 mg ............................................................................. 9.90 OP (15.5) Zithromax METHADONE HYDROCHLORIDE (ê subsidy) a) Only on a controlled drug form b) No patient co-payment payable c) Extemporaneously compounded methadone will only be reimbursed at the rate of the cheapest form available (methadone powder, not methadone tablets). d) For methadone hydrochloride oral liquid refer, page 159 Tab 5 mg ................................................................................. .10 10 (.) Pallidone DIAZEPAM (è subsidy) Rectal tubes 5 mg – Available on a PSO................................... . Rectal tubes 10 mg – Available on a PSO................................. .9 5 5 ✔ Stesolid ✔ Stesolid

104

GLUTEN FREE BREAD MIX – Special Authority see SA0 – Hospital pharmacy [HP] (è price) Powder .................................................................................... .9 1,000 g OP (5.4) NZB Low Gluten Bread Mix .51 (.55) Horleys Bread Mix 4. (.1) Bakels Gluten Free Health Bread Mix GLUTEN FREE FLOUR – Special Authority see SA0 – Hospital pharmacy [HP] (è price) Powder ..................................................................................... 5.6 ,000 g OP (1.0) Horleys Flour

Effective 1 October 2007

5 MESALAZINE (ê subsidy) Tab 400 mg – Retail pharmacy-Specialist ............................... 49.50 Suppos 500 mg ...................................................................... 5.0 Three months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber. 100 0 ✔ Asacol ✔ Asacol

▲

❋ Three months or six months, as applicable, dispensed all-at-once

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to Subsidy and Manufacturer’s Price - effective 1 October 2007 (continued)

4 DEXTROSE WITH ELECTROLYTES (ê subsidy) Soln with electrolytes................................................................. . (.44) 6.0 (6.66) COLESTIPOL HYDROCHLORIDE (è subsidy) Sachets 5 g ............................................................................ 16.1 CAPTOPRIL (è subsidy) ❋ Tab 1.5 mg .......................................................................... 10.40 ❋ Tab 5 mg ............................................................................. 1.40 ❋ Tab 50 mg ............................................................................. 19.00 DIGOXIN (è subsidy) ❋ Tab 6.5 µg – Available on a PSO ............................................. 6.94 ❋ Tab 50 µg – Available on a PSO ............................................ 15.1 ❋‡ Oral liq 50 µg per ml ............................................................ 16.60 500 ml OP Plasma-Lyte Oral 946 ml OP Pedialyte - Fruit 0 500 500 500 50 50 60 ml ✔ Colestid ✔ Apo-Captopril ✔ Apo-Captopril ✔ Apo-Captopril ✔ Lanoxin PG ✔ Lanoxin ✔ Lanoxin

4 51

METOPROLOL SUCCINATE (è price and alternate subsidy) ❋ Tab long-acting .5 mg – Higher subsidy of $6.0 per 0 with Endorsement ......................................... 5.0 0 (6.0) Betaloc CR ❋ Tab long-acting 4.5 mg – Higher subsidy of $.0 per 0 with Endorsement ......................................... 6.50 0 (.0) Betaloc CR ❋ Tab long-acting 95 mg – Higher subsidy of $1.0 per 0 with Endorsement ..................................... 11.0 0 (1.0) Betaloc CR ❋ Tab long-acting 190 mg – Higher subsidy of $1.00 per 0 with Endorsement ......................................... 0.5 0 (1.00) Betaloc CR Additional subsidy by endorsement is available for patients who: a) were being prescribed metoprolol succinate prior to 1 October 00; or b) have experienced a myocardial infarction. The prescription must be endorsed accordingly Note – Repeats for Betaloc CR tab long-acting will be fully subsidised where the initial dispensing was before 1 October 00. METOPROLOL TARTRATE (è subsidy) ❋ Tab 50 mg ............................................................................. 16.50 POVIDONE IODINE (ê price) Oint 10% .................................................................................. . POVIDONE IODINE (ê subsidy) Antiseptic soln 10% .................................................................. 6.0 OXYBUTYNIN (è subsidy) ❋ Oral liq 5 mg per 5 ml ............................................................. 50.40 100 5 g OP 500 ml ✔ Lopresor ✔ Betadine ✔ Betadine

55 65 65

4 ml OP ✔ Apo-Oxybutynin

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

S29 Unapproved medicine supplied under Section 9 Sole Subsidised Supply ‡ safety cap reimbursed

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to Subsidy and Manufacturer’s Price - effective 1 October 2007 (continued)

0 THYROXINE (è subsidy) ❋ Tab 50 µg .............................................................................. 4.14 ‡ Safety cap for extemporaneously compounded oral liquid preparations. ❋ Tab 100 µg ............................................................................ 50.9 ‡ Safety cap for extemporaneously compounded oral liquid preparations. PHENOXYMETHYLPENICILLIN (PENICILLIN V) (è subsidy) Grans for oral liq 15 mg per 5 ml – Available on a PSO ............................................................. 1.6 Grans for oral liq 50 mg per 5 ml – Available on a PSO ............................................................. 1. 1,000 1,000 ✔ Eltroxin ✔ Eltroxin

100 ml 100 ml

✔ AFT ✔ AFT

COLISTIN SULPHOMETHATE – Hospital pharmacy [HP]-Specialist – Subsidy by endorsement (è subsidy) Only if prescribed for dialysis or cystic fibrosis patient and the prescription is endorsed accordingly. Inj 150 mg ............................................................................. 65.00 1 ✔ Colistin-Link FUSIDIC ACID (è subsidy) Tab 50 mg – Hospital pharmacy [HP]-Specialist ................. 4.6 QUETIAPINE (ê subsidy) Tab 5 mg ............................................................................. 46.0 Tab 100 mg ........................................................................... 9.40 Tab 00 mg ......................................................................... 15.6 Tab 00 mg ......................................................................... 6.1 1 60 60 60 60 ✔ Fucidin ✔ Seroquel ✔ Seroquel ✔ Seroquel ✔ Seroquel ✔ Taxol ✔ Taxol ✔ Baxter ✔ Betaferon

9 11

PACLITAXEL – PCT only – Specialist – Special Authority SA01 (ê subsidy) Inj 0 mg ................................................................................ 90.00 1 Inj 100 mg ........................................................................... 99.0 1 Inj 1 mg for ECP ....................................................................... .9 1 mg INTERFERON BETA-1-BETA – Special Authority SA055 (ê subsidy) Inj million iu per 1 ml ....................................................... 10. 15

140

Effective 1 September 2007

9 METFORMIN HYDROCHLORIDE (ê subsidy) ❋ Tab 500 mg ............................................................................. 9.5 ❋ Tab 50 mg ............................................................................. .00 500 50 ✔ Metomin ✔ Metomin

WATER (ê subsidy) 1) On a prescription or Practitioner’s Supply Order only when on the same form as an injection listed in the Pharmaceutical Schedule requiring a solvent or diluent; or ) On a bulk supply order; or ) When used in the extemporaneous compounding of eye drops. Purified for inj 5 ml – Available on a PSO ................................... 9.1 50 ✔ AstraZeneca Purified for inj 10 ml – Available on a PSO ............................... 10. 50 ✔ AstraZeneca MALATHION (ê subsidy) Liq 0.5%.................................................................................... 4.99 (5.0) Three months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber. 00 ml AFT

▲

❋ Three months or six months, as applicable, dispensed all-at-once

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to Subsidy and Manufacturer’s Price - effective 1 September 2007 (continued)

6 96 HYDROCORTISONE BUTYRATE (è subsidy) Scalp lotn 0.1% ........................................................................ .5 NITROFURANTOIN (è subsidy) ❋ Tab 50 mg ............................................................................. 1.0 ❋ Tab 100 mg ........................................................................... 9.40 LITHIUM CARBONATE (è subsidy) Tab long-acting 400 mg ......................................................... 15.45 PHENYLEPHRINE HYDROCHLORIDE (è subsidy) ❋ Eye drops 0.1% ...................................................................... 4.4 100 ml OP ✔ Locoid 100 100 100 15 ml OP ✔ Nifuran ✔ Nifuran ✔ Priadel ✔ Prefrin

116 154

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

S29 Unapproved medicine supplied under Section 9 Sole Subsidised Supply ‡ safety cap reimbursed

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to General Rules

Effective 1 November 2007

The functions of PHARMAC are to perform the following, within the amount of funding provided to it in the Pharmaceutical Budget or to DHBs from their own budgets for the use of pharmaceuticals in their hospitals, as applicable, and in accordance with its annual plan and any directions given by the Minister (Section 10 of the Crown Entities Act): a) to maintain and manage a pharmaceutical schedule that applies consistently throughout New Zealand, including determining eligibility and criteria for the provision of subsidies; b) to manage incidental matters arising out of (a), including in exceptional circumstances providing for subsidies for the supply of pharmaceuticals not on the pharmaceutical schedule; c) to engage as it sees fit, but within its operational budget, in research to meet its objectives as set out in Section 4(a) of the Act; d) to promote the responsible use of pharmaceuticals; e) to manage the purchasing of any or all pharmaceuticals, whether used either in a hospital or outside it, on behalf of DHBs; f) any other functions given to PHARMAC by or under any enactment or authorised by the Minister. The policies and criteria set out in the Pharmaceutical Schedule and PHARMAC’s Operating Policies and Procedures arise out of, and are designed to help PHARMAC achieve and perform, PHARMAC’s objective and functions under the Act. However PHARMAC may, having regard to its public law obligations, depart from the strict application of those policies and criteria in certain exceptional cases where it considers this necessary or appropriate in the proper exercise of its statutory discretion and to give effect to its objective and functions, particularly with respect to: • Determining eligibility and criteria for the provision of subsidies: and • In exceptional circumstances providing for subsidies for the supply of pharmaceuticals not on the Pharmaceutical Schedule. 14 “Hospital Pharmacy-Specialist Prescription” means that the Community Pharmaceutical is not eligible for Subsidy unless it is supplied by a hospital or pharmacy contracted to the Funder to dispense as a hospital pharmacy: a) to an Outpatient; and b) on a Prescription signed by a Specialist. For the purposes of this definition, a “specialist” means a doctor who holds a current annual practicing certificate and who satisfies the criteria set out in paragraphs (a) or (b) or (c) of the definitions of Specialist below. “Retail Pharmacy-Specialist Prescription” means that the Community Pharmaceutical is only eligible for Subsidy if it is supplied on a Prescription, or Practitioner’s Supply Order, signed by a Specialist. For the purposes of this definition, a “specialist” means a doctor who holds a current annual practicing certificate and who satisfies the criteria set out in paragraphs (a) or (b) or (c) of the definitions of Specialist below. “Special Authority” means that the Community Pharmaceutical or Pharmaceutical Cancer Treatment is only eligible for Subsidy or additional Subsidy for a particular person if an application meeting the criteria specified in the Schedule has been approved, and the valid Special Authority number is present on the prescription.

▲

Three months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

❋ Three months or six months, as applicable, dispensed all-at-once

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Changes to Section G: Safety Cap Medicines

Effective 1 September 2007

OXYCODONE HYDROCHLORIDE Oral liq 5 mg per 5 ml .....................OxyNorm

Changes to Sole Subsidised Supply

Effective 1 November 2007

For the list of new Sole Subsidised Supply products effective 1 November 00 refer to the bold entries in the cumulative Sole Subsidised Supply table pages -16.

continued... Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy Unapproved medicine supplied under Section 9 Sole Subsidised Supply ‡ safety cap reimbursed

S29

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Delisted Items

Effective 1 November 2007

99 TIAPROFENIC ACID – Additional subsidy by Special Authority see SA091 – Retail pharmacy ❋ Cap long-acting 00 mg ............................................................ . 56 (1.51) Surgam SA

Effective 1 October 2007

9 105 TESTOSTERONE ENANTHATE – Retail pharmacy-Specialist Inj long-acting 250 mg - prefilled syringe ................................ 45.00 INFLUENZA VACCINE – Hospital pharmacy [Xpharm] Inj ........................................................................................... 5.00 MORPHINE SULPHATE a) Only on a controlled drug form b) No patient co-payment payable Suppos 5 mg........................................................................... 1.4 Suppos 10 mg ........................................................................ 19.14 Suppos 0 mg ........................................................................ 0.1 Suppos 0 mg ........................................................................ 1.9 DIAZEPAM Inj 5 mg per ml, ml – Subsidy by endorsement .................... 16.64 (.90) a) Only on a PSO b) PSO must be endorsed “not for anaesthetic procedures”. LORATADINE ❋ Tab 10 mg ................................................................................ .50 10 ✔ Primoteston ✔ Vaxigrip

1 1 1 1 10

✔ RMS ✔ RMS ✔ RMS ✔ RMS

Diazemuls

144

✔ Loraclear Hayfever Relief

145

SALMETEROL – See prescribing guideline Aerosol inhaler, 5 µg per dose .............................................. 6.46 10 dose OP ✔ Serevent Note: this product has been replaced by Serevent aerosol inhaler CFC-free SALBUTAMOL Nebuliser soln, 1 mg per ml, .5 ml – Available on a PSO .......... .0 (4.) Nebuliser soln, mg per ml, .5 ml – Available on a PSO .......... .5 (5.10) 0 Ventolin Nebules 0 Ventolin Nebules

146

AMINOACID FORMULA WITHOUT VALINE, LEUCINE AND ISOLEUCINE – Special Authority see SA0 – Hospital pharmacy [HP] See prescribing guideline Powder ................................................................................. 4. 500 g OP ✔ MSUD Aid III

Effective 1 September 2007

6 HYOSCINE N-BUTYLBROMIDE ❋ Tab 10 mg ............................................................................... 6.65 (10.5) Three months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber. 100 Buscopan

▲

❋ Three months or six months, as applicable, dispensed all-at-once

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Delisted Items - effective 1 September 2007 (continued)

5 LISINOPRIL ❋ Tab 5 mg ................................................................................. . (4.91) ❋ Tab 10 mg ............................................................................... .16 (.14) ❋ Tab 0 mg ............................................................................... .91 (10.10) 0 Prinivil 0 Prinivil 0 Prinivil

CEFTRIAXONE SODIUM – Hospital pharmacy [HP] – Subsidy by endorsement a) Available on a PSO b) Subsidised only if prescribed for a dialysis or cystic fibrosis patient, or the treatment of confirmed ciprofloxacin-resistant gonorrhoea, or the treatment of suspected meningitis in patients who have a known allergy to penicillin, and the prescription or PSO is endorsed accordingly. Inj 50 mg ................................................................................ 4.00 1 ✔ Rocephin IV ACICLOVIR ❋ Tab dispersible 00 mg ............................................................ .9 (10.00) .1 (4.5) ❋ Tab dispersible 400 mg .......................................................... .46 (6.00) ❋ Tab dispersible 00 mg .......................................................... 1.09 (6.0) VALACICLOVIR Tab 500 mg ............................................................................. 1.5 (54.6) 4.4 (16.0) PAROXETINE HYDROCHLORIDE Tab 0 mg ............................................................................... 5.90 (5.0) 100 Acicvir 90 Zovirax 40 Acicvir 100 Acicvir 10 Valtrex 0 Valtrex 0 Aropax ✔ Zyprexa ✔ Zyprexa ✔ Zyprexa

116

OLANZAPINE – Special Authority see SA041– Retail pharmacy Tab .5 mg ............................................................................ 54. 0 Tab 5 mg ............................................................................. 10.44 0 Tab 10 mg ........................................................................... 19.10 0 Note – Zyprexa tab .5 mg, 5 mg and 10 mg tablet pack size is still subsidised. TRIFLUOPERAZINE HYDROCHLORIDE Tab 5 mg ................................................................................ 15.9 (1.) 11

Stelazine Section 9 S29 10 Leucovorin 5 ml OP ✔ Alphagan

CALCIUM FOLINATE Tab 15 mg – PCT – Hospital pharmacy [HP]-Specialist .......... .90 (55.60) BRIMONIDINE TARTRATE – Retail pharmacy-Specialist ❋ Eye Drops 0.% ........................................................................ .95

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

S29 Unapproved medicine supplied under Section 9 Sole Subsidised Supply ‡ safety cap reimbursed

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Delisted Items - effective 1 September 2007 (continued)

15 GLUTEN FREE BREAD MIX – Special Authority see SA0 – Hospital pharmacy [HP] Powder ..................................................................................... 4. 1,000 g OP (.6)

Bakels Gluten Free Bread Mix

▲

Three months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

❋ Three months or six months, as applicable, dispensed all-at-once

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Items to be Delisted

Effective 1 December 2007

64 CETOMACROGOL ❋ Cream BP .................................................................................. .0 (4.5) MALATHION Liq 0.5%.................................................................................... 4.99 (5.0) SODIUM CITRO-TARTRATE ❋ Grans eff 4 g sachets ............................................................... 1.0 (.40) Note - the pack size of Ural will continue to be available fully subsidised. 500 g IPW 00 ml AFT Ural

Effective 1 January 2008

9 METFORMIN HYDROCHLORIDE ❋ Tab 500 mg ............................................................................. 9.5 ❋ Tab 50 mg ............................................................................. .00 DEXTROSE WITH ELECTROLYTES Soln with electrolytes ................................................................ . (.44) 6.0 (6.66) INFLUENZA VACCINE – Hospital pharmacy [Xpharm] Inj.......................................................................................... .50 500 50 500 ml OP Plasma-Lyte Oral 946 ml OP Pedialyte - Fruit 1 ✔ Fluvax ✔ Metomin ✔ Metomin

Effective 1 February 2008

104

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

S29 Unapproved medicine supplied under Section 9 Sole Subsidised Supply ‡ safety cap reimbursed

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Items to be delisted - effective 1 March 2008

INSULIN ISOPHANE WITH INSULIN NEUTRAL ▲ Inj human with neutral insulin 100 u per ml .............................. 5.6 ▲ Inj human with neutral insulin 100 u per ml, ml ..................... 4.66 ACEBUTOLOL ❋ Tab 400 mg ............................................................................ .6 POVIDONE IODINE Oint 10% ................................................................................... . 6. (.0) a) Maximum of 100 g per prescription b) Only on a prescription Antiseptic soln 10% .................................................................. 6.4 64.0 PIMOZIDE – Retail pharmacy-Specialist Tab 4 mg ............................................................................... 11. 10 ml OP 5 ✔ Mixtard 50 ✔ PenMix 10 ✔ PenMix 20 ✔ ACB ✔ Biocil Betadine 500 ml 5,000 ml ✔ Biocil ✔ Biocil

55 65

100 5 g OP 100 g OP

116

✔ Orap Forte S29

Effective 1 April 2008

5 SULPHASALAZINE Enema g per 100 ml - Retail pharmacy - Specialist ............... .40 (4.00) DEXTROSE ❋ Inj 50%, 10 ml – Available on a PSO .......................................... .5 BENZATHINE BENZYLPENICILLIN Injection 1. mega u – Available on a PSO ............................ 160.00 Salazopyrin 5 10 ✔ Mayne ✔ Pan Benzathine Benzylpenicillin

IBUPROFEN – Additional subsidy by Special Authority see SA091 – Retail pharmacy ❋ Tab 600 mg ............................................................................. 5. 100 (.0)

Brufen

99 11

TENOXICAM – Additional subsidy by Special Authority see SA091 – Retail pharmacy ❋ Inj 10 mg per ml, ml – Available on a PSO ............................ 10.00 5 ✔ Tilcotil DIMENHYDRINATE ❋ Tab 50 mg ............................................................................... 0.59 (.0) THIORIDAZINE HYDROCHLORIDE Tab 50 mg ............................................................................. 10.66 PILOCARPINE ❋ Eye drops % ........................................................................... 6.41 10 Dramamine 90 15 ml OP ✔ Aldazine ✔ Pilopt

11 15

▲

Three months supply may be dispensed at one time if endorsed “certified exemption” by the prescriber.

❋ Three months or six months, as applicable, dispensed all-at-once

Check your Schedule for full details Schedule page ref

Subsidy (Mnfr’s price) $

Per

Brand or Generic Mnfr ✔ fully subsidised

Items to be delisted - effective 1 April 2008 (continued)

10 SOYA INFANT FORMULA – Special Authority see SA0604 – Retail pharmacy Powder ..................................................................................... 6.4 900 g OP (1.)

Infasoy

Effective 1 May 2008

4 WATER 1) On a prescription or Practitioner’s Supply Order only when on the same form as an injection listed in the Pharmaceutical Schedule requiring a solvent or diluent; or ) On a bulk supply order; or ) When used in the extemporaneous compounding of eye drops. Purified for inj 5 ml – Available on a PSO ................................... 9.1 50 ✔ AstraZeneca Purified for inj 10 ml – Available on a PSO ............................... 10. 50 ✔ AstraZeneca RITONAVIR – Special Authority see SA09 – Hospital pharmacy [HP1] Oral liq 0 mg per ml ............................................................ . 40 ml OP ✔ Norvir

95 104

151 160

Patients pay a manufacturer’s surcharge when the Manufacturer’s Price is greater than the Subsidy

S29 Unapproved medicine supplied under Section 9 Sole Subsidised Supply ‡ safety cap reimbursed

Contracted Pharmaceutical Description

Brand

Price ($) (ex man. excl. GST)

Per

DV Limit

DV Limit DV applies Pharmaceutical from

Section H changes to Part II

Effective 1 November 2007

DIAZEPAM (è price) Rectal tubes 5 mg ..........................Stesolid Rectal tubes 10 mg ........................Stesolid . .9 5 5 100 100 1% 1% Jan-0 Jan-0 Dosan Dosan

DOXAZOSIN MESYLATE Tab mg........................................Apo-Doxazosin 4.1 Tab 4 mg........................................Apo-Doxazosin 6. Note – Dosan tab mg and 4 mg to be delisted 1 January 00 FERROUS SULPHATE Oral liq 150 mg per 5 ml .................Ferodan Note – Ferro-liquid to be delisted 1 January 00 10.0

500 ml

Jan-0

Ferro-liquid

GANCICLOVIR Cap 50 mg ...................................Cymevene 441.00 Note – Cymevene cap 50 mg delisted 1 November 00

METHADONE HYDROCHLORIDE Inj 10 mg per ml, 1 ml ....................AFT 5.00 10 Inj 10 mg per ml, 1 ml ....................AFT 6.00 5 Note – AFT methadone hydrochloride inj 10 mg per ml, 1 ml delisted 1 November 00 POVIDONE IODINE Antiseptic soln 10% ........................Riodine Antiseptic soln 10% ........................Riodine QUETIAPINE Tab 5 mg......................................Quetapel Tab 100 mg....................................Quetapel Tab 00 mg....................................Quetapel Tab 00 mg....................................Quetapel RANITIDINE HYDROCHLORIDE Oral liq 150 mg per 10 ml ...............Peptisoothe SODIUM CHLORIDE Inj 0.9%, 0 ml ...............................Multichem WATER Purified for inj 5 ml .........................Multichem .95 6.0 0.6 41.5 0. 119.5 .95 .6 9.1 100 ml 500 ml 90 90 90 90 00 ml 0 50 1% Feb-0 1% Jan-0 Zantac

AstraZeneca Pharmacia Purified for inj 10 ml .......................Multichem 10. 50 1% Feb-0 AstraZeneca Pharmacia Note – removal of the AstraZeneca brand of water purified for inj 5 ml and 10 ml as a DV Pharmaceutical following it’s discontinuation.

Products with Hospital Supply Status (HSS) are in bold.

(B) – Subject only to part (b) of the definition of “DV Pharmaceutical”

Contracted Pharmaceutical Description

Brand

Price ($) (ex man. excl. GST)

Per

DV Limit

DV Limit DV applies Pharmaceutical from

Section H changes to Part II - effective 1 October 2007

ALENDRONATE SODIUM WITH CHOLECALCIFEROL Tab 0 mg with cholecalciferol ,00 iu .....................................Fosamax Plus CAPTOPRIL Tab 1.5 mg...................................Apo-Captopril Tab 5 mg......................................Apo-Captopril Tab 50 mg......................................Apo-Captopril CITALOPRAM HYDROBROMIDE Tab 0 mg......................................Citalopram - Rex COLISTIN SULPHOMETHATE Inj 150 mg......................................Colistin-Link FUSIDIC ACID (è price) Tab 50 mg....................................Fucidin HALOPERIDOL (è price) Inj 5 mg per ml, 1 ml ......................Serenace HYDROCORTISONE ACETATE Rectal foam 10%, CFC-Free (14 applications).......................Colifoam Note – change in presentation description ISOFLURANE Liq 50 ml bottle ...........................Forthane Abbott Forane Note – change in brand name only LACTULOSE Oral liq 10 g per 15 ml ....................Duphalac

5.91 10.40 1.40 19.00

4 500 500 500 1% 1% 1% Dec-0 Dec-0 Dec-0 Capoten Captohexal Capoten Captohexal Capoten Captohexal

.50 65.00 4.6 1.04

1 1 10 1% Dec-0 (B)

1.10

1.1 g

Dec-06

(B)

99.00

50 ml

Jan-0

Aerrane Rhodia

6.65

1000 ml

Dec-0

Actilax Laevolac Apo-Loratadine Aridine Arrow-Loratadine Claratyne Lorastyne Lora-tabs Lorfast Tirlor

LORATADINE Tab 10 mg......................................Loraclear .5 Hayfever Relief

100

Dec-0

MACROGOL 50 Powder 1.15 g, sachets ..............Movicol

1.14

Products with Hospital Supply Status (HSS) are in bold.

(B) – Subject only to part (b) of the definition of “DV Pharmaceutical”

Contracted Pharmaceutical Description

Brand

Price ($) (ex man. excl. GST)

Per

DV Limit

DV Limit DV applies Pharmaceutical from

Section H changes to Part II - effective 1 October 2007 (continued)

MESALAZINE Suppos 500 mg..............................Asacol Suppos 1 g.....................................Pentasa Tab 400 mg....................................Asacol OMEPRAZOLE Cap 10 mg .....................................Dr Reddy’s Omeprazole Cap 0 mg .....................................Dr Reddy’s Omeprazole Cap 40 mg .....................................Dr Reddy’s Omeprazole 5.0 50.96 49.50 .99 4. 5.01 0 100

OXYBUTYNIN Oral liq 5 mg per 5 ml .....................Apo-Oxybutynin 50.40 Tab 5 mg........................................Apo-Oxybutynin 44.9 PACLITAXEL (ê price) Inj 0 mg........................................Taxol Inj 100 mg......................................Taxol PHENOXYMETHYLPENICILLIN (PENICILLIN V) Grans for oral liq 15 mg per 5 ml ........................AFT Grans for oral liq 50 mg per 5 ml ........................AFT PODOPHYLLOTOXIN (è price) Soln 0.5% ......................................Condyline POVIDONE IODINE Alcohol skin preparation 10% with 0% alcohol ...............................Betadine Skin Prep Antiseptic soln 10% ........................Betadine Oint 10% ........................................Betadine QUETIAPINE (ê price) Tab 5 mg......................................Seroquel Tab 100 mg....................................Seroquel Tab 00 mg....................................Seroquel Tab 00 mg....................................Seroquel SIMVASTATIN Tab 10 mg......................................SimvaRex Tab 0 mg......................................SimvaRex Tab 40 mg......................................SimvaRex 90.00 99.0

4 ml 500 1 1

1% 1% 1% 1%

Dec-0 Dec-0 Sept-05 Sept-05

(B) (B) Anzatax Paclitaxel Ebewe Anzatax Paclitaxel Ebewe

1.6 1. .00

100 ml 100 ml .5 ml

1% 1%

Dec-0 Dec-0

(B) (B)

.1 6.4 . 46.0 9.40 15.6 6.1 .1 .1 4.9

500 ml 500 ml 5 g 60 60 60 60 0 0 0

Products with Hospital Supply Status (HSS) are in bold.

(B) – Subject only to part (b) of the definition of “DV Pharmaceutical”

Contracted Pharmaceutical Description

Brand

Price ($) (ex man. excl. GST)

Per

DV Limit

DV Limit DV applies Pharmaceutical from

Section H changes to Part II - effective 1 October 2007 (continued)

SODIUM ACID PHOSPHATE Enema 16% with sodium phosphate % ............................Fleet Phosphate Enema

.50

Effective 1 September 2007

AZITHROMYCIN Tab 500 mg....................................ArrowAzithromycin METHADONE HYDROCHLORIDE Tab 5 mg........................................PSM OXYCODONE HYDROCHLORIDE Inj 10 mg per ml, 1 ml ....................OxyNorm Inj 10 mg per ml, ml ....................OxyNorm Oral liq 5 mg per 5 ml .....................OxyNorm 9.90 1% Nov-0 Zithromax

.10 14.40 .0 11.0

10 5 5 50 ml

1% 1% 1% 1%

Nov-0 Nov-0 Nov-0 Nov-0

Pallidone (B) (B) (B)

Effective 1 August 2007

EXEMESTANE Tab 5 mg......................................Aromasin 15.00 0

FLUOROURACIL SODIUM (ê price and addition of HSS) Inj 5 mg per ml 100 ml .................Mayne 1.55 1 1% Oct-0 (B) 4.95 1 1% Oct-0 Mayne Inj 50 mg per ml, 10 ml ..................Fluorouracil Ebewe Inj 50 mg per ml, 0 ml ..................Fluorouracil .60 1 1% Oct-0 Mayne Ebewe Inj 50 mg per ml, 50 ml ..................Fluorouracil 1.50 1 1% Oct-0 Mayne Ebewe Inj 50 mg per ml, 100 ml ................Fluorouracil 4.00 1 1% Oct-0 (B) Ebewe Note – Mayne’s brand of Fluorouracil sodium inj 50 mg per ml, 10 ml, 0 ml and 50 ml to be delisted 1 October 00 GABAPENTIN (ê price) Cap 100 mg ...................................Neurontin Cap 00 mg ...................................Neurontin Cap 400 mg ...................................Neurontin Tab 600 mg....................................Neurontin 15.6 4.00 6.66 9.9 100 100 100 100 00 ml 1% Oct-0 Nurofen

HYDROXOCOBALAMIN (Delisted effective 1 August 00) Inj 1 mg per ml, 1 ml ......................Neo-Cytamen 10.4 IBUPROFEN Oral liq 100 mg per 5 ml .................Fenpaed .49

Products with Hospital Supply Status (HSS) are in bold.

(B) – Subject only to part (b) of the definition of “DV Pharmaceutical”

Contracted Pharmaceutical Description

Brand

Price ($) (ex man. excl. GST)

Per

DV Limit

DV Limit DV applies Pharmaceutical from

Section H changes to Part II - effective 1 August 2007 (continued)

LOPINAVIR WITH RITONAVIR Tab 00 mg with ritonavir 50 mg ....Kaletra Oral liq 0 mg with ritonavir 0 mg per ml ........................................Kaletra MESNA (addition of HSS) Inj 100 mg per ml, 4 ml ..................Uromitexan Inj 100 mg per ml, 10 ml ................Uromitexan OXYCODONE HYDROCHLORIDE Tab controlled-release 5 mg ...........OxyContin ZIPRASIDONE Cap 0 mg .....................................Zeldox Cap 40 mg .....................................Zeldox Cap 60 mg .....................................Zeldox Cap 0 mg .....................................Zeldox 5.00 5.00 109.6 51. .51 . 164. 4.1 9.56 10 00 ml 15 15 0 60 60 60 60 1% 1% Oct-0 Oct-0 (B) (B)

Section H changes to Part IV

Effective 1 November 2007

GANCICLOVIR Cap 50 mg Cymevene Inj 500 mg Cymevene For prophylaxis and treatment of CMV-associated disease in immunocompromised patients and following organ transplant. Note – Cymevene cap 50 mg delisted 1 November 00

Products with Hospital Supply Status (HSS) are in bold.

(B) – Subject only to part (b) of the definition of “DV Pharmaceutical”

Index

Pharmaceuticals and brands A Abbott Forane .................................................... ACB ................................................................... 5 Acebutolol.......................................................... 5 Acetopt .............................................................. 6 Acetylcysteine.............................................. 1, 6 Aciclovir ...................................................... 1, Acicvir ............................................................... Aldazine ............................................................. 5 Alendronate sodium with cholecalciferol ............. Alphagan ........................................................... Aminoacid formula without valine, leucine and isoleucine ................................................. 1 Apo-Captopril ............................................... 6, Apo-Doxazosin............................................. 1, Apo-Ipravent ...................................................... 1 Apo-Oxybutynin ........................................... 6, 9 Apo-Timop......................................................... Aromasin ........................................................... 40 Aropax ............................................................... Arrow-Azithromycin ..................................... 19, 40 Asacol ......................................................... 5, 9 Aspirin ............................................................... 1 Azithromycin .................................... 19, 5, 4, 40 B Bakels Gluten Free Bread Mix ............................. Bakels Gluten Free Health Bread Mix ................... 5 Benzathine benzylpenicillin ................................. 5 Betadine........................................... 5, 6, 5, 9 Betadine Skin Prep ............................................. 9 Betaferon ........................................................... Betagan ............................................................. 1 Betaloc CR ................................................... 0, 6 Betaxolol hydrochloride ...................................... 1 Betoptic ............................................................. 1 Betoptic S .......................................................... 1 Biocil ................................................................. 5 Brimonidine tartrate ...................................... , Brimonidine tartrate with timolol maleate............. Brufen.......................................................... 1, 5 Budesonide with eformoterol .............................. 1 Buscopan .......................................................... 1 C Calcium folinate ................................................. Captopril ...................................................... 6, Ceftriaxone sodium ............................................ Cellcept ............................................................. 0 Cetomacrogol .................................................... 4 Ciloxan............................................................... 1 Ciprofloxacin ...................................................... 1 Citalopram - Rex .......................................... 1, Citalopram hydrobromide ............................. 1, Colestid ............................................................. 6 Colestipol hydrochloride ..................................... 6 Colifoam ...................................................... 0, Colistin-Link ................................................. , Colistin sulphomethate ................................. , Combigan .......................................................... Condyline........................................................... 9 Cosopt ............................................................... Cymevene.................................................... , 41 D Dexamethasone ................................................. 1 Dexamethasone with framycetin and gramicidin ................................................ 1 Dexamethasone with neomycin and polymyxin b sulphate ................................ 1 Dextrose ............................................................ 5 Dextrose with electrolytes............................. 6, 4 Diazemuls .......................................................... 1 Diazepam............................................... 5, 1, Diclofenac sodium ............................................. 1 Digoxin .............................................................. 6 Dimenhydrinate .................................................. 5 Dorzolamide hydrochloride ................................. Dorzolamide hydrochloride with timolol maleate................................................ Doxazosin mesylate ..................................... 1, Dramamine ........................................................ 5 Dr Reddy’s Omeprazole................................ 1, 9 Duphalac ..................................................... 1, E Eltroxin .............................................................. Ethics Aspirin EC................................................ 1 Exemestane ....................................................... 40 F Fat ..................................................................... Fenpaed ............................................................. 40 Ferodan ....................................................... 1, Ferrous sulphate .......................................... 1, Fleet Phosphate Enema ...................................... 40 Flucon................................................................ 1 Fluorometholone ................................................ 1 Fluorouracil Ebewe ............................................. 40 Fluorouracil sodium............................................ 40 Fluvax ................................................................ 4 Forthane ............................................................ Fosamax Plus .................................................... Fucidin ......................................................... , Fusidic acid.................................................. , G Gabapentin ........................................................ 40 Ganciclovir................................................... , 41 Genoptic ............................................................ 1

Index

Pharmaceuticals and brands Gentamicin sulphate ........................................... 1 Gluten free bread mix ................................... 5, Gluten free flour ................................................. 5 H Haloperidol ........................................................ Horleys Bread Mix .............................................. 5 Horleys Flour...................................................... 5 Hydrocortisone acetate ................................ 0, Hydrocortisone butyrate ..................................... Hydroxocobalamin ............................................. 40 Hyoscine N-butylbromide ................................... 1 I Ibuprofen ............................................... 1, 5, 40 Infasoy .............................................................. 6 Influenza vaccine.......................................... 1, 4 Insulin isophane with insulin neutral.................... 5 Interferon beta-1-beta......................................... Ipratropium bromide ........................................... 1 Isoflurane ........................................................... K Kaletra ............................................................... 41 L Lactulose ..................................................... 1, Lanoxin .............................................................. 6 Lanoxin PG ........................................................ 6 Leucovorin ......................................................... Levobunolol ....................................................... 1 Lisinopril ............................................................ Lithium carbonate .............................................. Locoid ............................................................... Lopinavir with ritonavir ....................................... 41 Lopresor ............................................................ 6 Loraclear Hayfever Relief........................ 19, 1, Loratadine.............................................. 19, 1, M Macrogol 50 ............................................ 1, Malathion ..................................................... , 4 Maxidex ............................................................. 1 Maxitrol.............................................................. 1 Mesalazine ............................................. 1, 5, 9 Mesna ............................................................... 41 Metformin hydrochloride .............................. , 4 Methadone hydrochloride ..... 1, 19, 5, 4, , 40 Metomin ...................................................... , 4 Metoprolol succinate .................................... 0, 6 Metoprolol tartrate .............................................. 6 Midazolam ......................................................... 1 Minims .............................................................. Mixtard 50 ......................................................... 5 Morphine sulphate.............................................. 1 Movicol........................................................ 1, MSUD Aid III ...................................................... 1 Mycophenolate mofetil ....................................... 0 N Neo-Cytamen ..................................................... 40 Neurontin ........................................................... 40 Nifuran ............................................................... Nitrofurantoin ..................................................... Norvir .......................................................... 1, 6 NZB Low Gluten Bread Mix ................................. 5 O Olanzapine ......................................................... Omeprazole.................................................. 1, 9 Ondansetron ...................................................... 4 Orap Forte .......................................................... 5 Oxybutynin ................................................... 6, 9 Oxycodone hydrochloride ................. 19, 0, 40, 41 OxyContin .......................................................... 41 OxyNorm ............................................... 19, 0, 40 P Paclitaxel ..................................................... , 9 Paediatric products ............................................ Pallidone ...................................................... 5, 4 Pan Benzathine Benzylpenicillin .......................... 5 Paroxetine hydrochloride .................................... Parvolex ............................................................. 6 Pedialyte - Fruit ............................................ 6, 4 PenMix 10 ......................................................... 5 PenMix 0 ......................................................... 5 Pentasa ....................................................... 1, 9 Peptisoothe .................................................. 1, Phenoxymethylpenicillin (Penicillin V) ..... 0, , 9 Phenylephrine hydrochloride .............................. Pilocarpine ................................................... , 5 Pilopt ................................................................. 5 Pimozide ............................................................ 5 Plasma-Lyte Oral.......................................... 6, 4 Podophyllotoxin ................................................. 9 Povidone iodine ......................... 5, 6, 5, , 9 Pred Forte .......................................................... Pred Mild ........................................................... Prednisolone acetate .......................................... Prefrin................................................................ Priadel ............................................................... Primoteston ....................................................... 1 Prinivil................................................................ Q Quetapel ...................................................... 1, Quetiapine.................................. 1, 0, , , 9 R Ranitidine hydrochloride ............................... 1, Riodine ........................................................ 5, Ritonavir ...................................................... 1, 6 Rocephin IV .......................................................

Index

Pharmaceuticals and brands S S6 Soy............................................................. 1 Salazopyrin ........................................................ 5 Salbutamol......................................................... 1 Salmeterol ......................................................... 1 Serenace ........................................................... Serevent ............................................................ 1 Seroquel ................................................ 0, , 9 SimvaRex .................................................... 1, 9 Simvastatin .................................................. 1, 9 Sodium acid phosphate ...................................... 40 Sodium chloride ........................................... 1, Sodium citro-tartrate .......................................... 4 Sofradex ............................................................ 1 Soya infant formula ...................................... 1, 6 Stelazine Section 9 ........................................... Stesolid ....................................................... 5, Sulphacetamide sodium ..................................... 6 Sulphasalazine ................................................... 5 Surgam SA ........................................................ 1 Symbicort Rapihaler ........................................... 1 T Taxol ........................................................... , 9 Tenoxicam ......................................................... 5 Testosterone enanthate ...................................... 1 Thioridazine hydrochloride.................................. 5 Thyroxine ........................................................... Tiaprofenic acid ................................................. 1 Tilcotil ................................................................ 5 Timolol maleate.................................................. Timoptol XE ....................................................... Tobramycin........................................................ Tobrex ............................................................... Trifluoperazine hydrochloride .............................. Trusopt .............................................................. U Ural.................................................................... 4 Uromitexan ........................................................ 41 V Valaciclovir ........................................................ Valtrex ............................................................... Vaxigrip ............................................................. 1 Ventolin Nebules ................................................ 1 Voltaren Ophtha ................................................. 1 W Water ..................................................... , 6, Z Zeldox ................................................................ 41 Ziprasidone ........................................................ 41 Zithromax..................................................... 5, 4 Zofran ................................................................ 4 Zofran Zydis ....................................................... 4 Zovirax ......................................................... 1, Zyprexa ..............................................................

While care has been taken in compiling this Update, Pharmaceutical Management Agency takes no responsibility for any errors or omissions and shall not be liable to any person for any damages or loss arising out of reliance by that person for any purpose on any of the contents of this Update. Errors and omissions brought to the attention of Pharmaceutical Management Agency will be corrected if necessary by an erratum or otherwise in the next edition of the Update. Pharmaceutical Management Agency Level 14 Cigna House, 40 Mercer Street PO Box 10 254 Wellington, New Zealand Telephone 64 4 460 4990 Facsimile 64 4 460 4995 Freephone information line (9am - 4pm weekdays) 0800 66 00 50 www.pharmac.govt.nz

Metadata

Title

Schedule Update - effective 1 November 2007

Abstract

07 UPDATE New Zealand Pharmaceutical Schedule Effective 1 November 2007 Cumulative for September, October and November 2007 Section H cumulative for August, September, October and November 2007 Contents Summary of PHARMAC decisions … 3 Betaloc CR still fully funded ……

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