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Generic Medicines and Brand Changes

Mike Bignall Therapeutic Group Manager


Life cycle of a medicine

Time

Research & Development

Patent Life

Generic Entry



Generics = large price reductions

Product Pioglitazone Baclofen Fluconazole (200 mg) Buspirone (10 mg) Fluconazole (50 mg) Propranolol Buspirone (5 mg) Selegiline Doxycycline Pindolol Use/disease treated Type 2 diabetes Muscle relaxant Fungal infections Anti-anxiety Fungal infections Heart disease Anti-anxiety Parkinsons disease Antibiotic Heart disease Price reduction 93 - 96% 93.6% 93.4% 90.8% 90.8% 88.2% 83.4% 82.2% 82.0% 80.9%


Case Study – Fluconazole 200 mg (per pack)

$628

$1.9 million $41.50

1993 2005

$19.05

2009


International Use of Generics

60

volume of generics (%)

50 40 30 20 10 0

U K ia U SA us tr al ad a al a N ew Ze nd

OECD Health Policy Studies, Pharmaceutical Pricing Policies in a Global Market (www.oecd.org.nz) released September 2008.

A

C

an


•$70

• from

million

in 2009

•saved

generic competition


It has to be safe and effective


Careful Choices

• • • • • •

Internal analysis and consideration on products Wide consultation Objective clinical advice Tender issued Tender Evaluation Final consideration and approval


Patient information


Generic Medicines – Health Professional Series

Generic Medicines & Brand Changes


Monitoring brand changes

• • • •

Direct communication to PHARMAC Public comment Direct relationships with health professionals CARM


Key findings of consumer research

High general awareness of generic medicines Key role of doctors and pharmacists Experience with generic medicines reduces anxieties Less than 1/3 of people received information


4 out of 5 consumers want:

Information about NZ quality and safety checks Evidence core ingredients are the same Information about the effectiveness of the generic medicine

5%


Consumers PHARMAC Pharmacists

Improving Brand Changes Medsafe Prescribers Industry

Metadata

Title

PHARMAC Forum 09 - Generic Medicines and Brand Changes.ppt

Abstract

Generic Medicines and Brand Changes Mike Bignall Therapeutic Group Manager Life cycle of a medicine Time Research & Development Patent Life Generic Entry Generics = large price reductions Product Pioglitazone Baclofen Fluconazole (200 mg) Buspirone (10 mg) Fluconazole (50 mg)…

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