Pharmaceutical Schedule - effective 1 December 2011 (text extract)

This is the text extract for Pharmaceutical Schedule - effective 1 December 2011, browse documents here.

Pharmaceutical Management Agency

December 2011

New Zealand Pharmaceutical Schedule

December 2011

Volume 18 Number 3

Editors: Kaye Wilson, Rebecca Bloor & Donna Jennings email: schedule@pharmac.govt.nz Telephone +64 4 460 4990 Facsimile +64 4 460 4995 Level 9, 40 Mercer Street PO Box 10 254 Wellington Freephone Information Line 0800 66 00 50 (9am – 5pm weekdays) Circulation Published each April, August and December. Changes to the contents are published in monthly updates. Annual subscription includes three Pharmaceutical Schedule books, 12 updates and occasional information on rule changes and news items. The Schedule is distributed free of charge to over 9,000 health professionals, and is also available on an annual subscription. Prices $22.22 One Schedule book $4.44 One Update $120.00 Annual subscription All prices include postage and exclude GST. Production Typeset automatically from XML and TEX. XML version of the Schedule available from www.pharmac.govt.nz/schedule/pub/archive/ Programmers Anrik Drenth & John Geering email: texschedule@pharmac.govt.nz c Pharmaceutical Management Agency ISSN 1179-3686 pdf ISSN 1172-9376 print This work is licensed under the Creative Commons Attribution 3.0 New Zealand licence. In essence, you are free to copy, distribute and adapt it, as long as you attribute the work to PHARMAC and abide by the other licence terms. To view a copy of this licence, visit: creativecommons.org/licenses/by/3.0/nz/. Attribution to PHARMAC should be in written form and not by reproduction of the PHARMAC logo. While care has been taken in compiling this Schedule, PHARMAC takes no responsibility for any errors or omissions, and shall not be liable for any consequences arising there from.

Introducing PHARMAC

Section A Section B

General Rules 13 Alimentary Tract & Metabolism 26

Blood & Blood Forming Organs 40 Cardiovascular System 47 Dermatologicals 56 Genito Urinary System 66 Hormone Preparations – Systemic 72 Infections – Agents For Systemic Use 79 Musculoskeletal System 97 Nervous System 114 Oncology Agents & Immunosuppressants 140 Respiratory System & Allergies 159 Sensory Organs 166 Various 171

Section C Extemporaneous Compounds (ECPs) 171 Section D Section E

Special Foods 178 Practitioner’s Supply Orders 198 Rural Areas 202

Section F Section G

Dispensing Period Exemptions 203 Safety Cap Medicines 205 Index 208

Introducing PHARMAC

PHARMAC, the Pharmaceutical Management Agency, is a Crown entity established pursuant to the New Zealand Public Health and Disability Act 2000 (The Act). The primary objective of PHARMAC is to secure for eligible people in need of pharmaceuticals, the best health outcomes that are reasonably achievable from pharmaceutical treatment and from within the amount of funding provided. The PHARMAC Board consists of up to ﬁve members appointed by the Minister of Health. All decisions relating to PHARMAC’s operation are made by or under the authority of the Board. In particular, Board members decide on the strategic direction of PHARMAC and may decide which community pharmaceuticals should be subsidised and at what levels, and determine national prices for some pharmaceuticals to be purchased by and used in DHB Hospitals, and whether or not special conditions are to be applied to such purchases. Members of the PHARMAC Board Stuart McLauchlan Kura Denness David Kerr Anne Kolbe Jens Mueller Decisions taken by the PHARMAC Board members, or made under the authority of the Board, incorporate a balanced view of the needs of prescribers and patients. The aim is to achieve long-term gains and efﬁcient ways of making pharmaceuticals available to the community and for DHB Hospitals to purchase them. The following attend PHARMAC’s Board meetings as observers G Murray Georgel, CE MidCentral DHB G Kate Russell, Chair Consumer Advisory Committee G Carl Burgess, Chair Pharmacology and Therapeutics Advisory Committee (PTAC) The functions of PHARMAC are to perform the following, within the amount of funding provided to it in the Pharmaceutical Budget or to DHBs from their own budgets for the use of pharmaceuticals in their hospitals, as applicable, and in accordance with its annual plan and any directions given by the Minister (Section 103 of the Crown Entities Act): a) to maintain and manage a pharmaceutical schedule that applies consistently throughout New Zealand, including determining eligibility and criteria for the provision of subsidies; b) to manage incidental matters arising out of (a), including in exceptional circumstances providing for subsidies for the supply of pharmaceuticals not on the pharmaceutical schedule; c) to engage as it sees ﬁt, but within its operational budget, in research to meet its objectives as set out in Section 47(a) of the Act; d) to promote the responsible use of pharmaceuticals; e) to manage the purchasing of any or all pharmaceuticals, whether used either in a hospital or outside it, on behalf of DHBs; f) any other functions given to PHARMAC by or under any enactment or authorised by the Minister. The policies and criteria set out in the Pharmaceutical Schedule and PHARMAC’s Operating Policies and Procedures arise out of, and are designed to help PHARMAC achieve and perform, PHARMAC’s objective and functions under the Act. However PHARMAC may, having regard to its public law obligations, depart from the strict application of those policies and criteria in certain exceptional cases where it considers this necessary or appropriate in the proper exercise of its statutory discretion and to give effect to its objective and functions, particularly with respect to: G Determining eligibility and criteria for the provision of subsidies; and G In exceptional circumstances providing for subsidies for the supply of pharmaceuticals not on the Pharmaceutical Schedule. Decision Criteria PHARMAC updates the Pharmaceutical Schedule at regular intervals to notify prescribers, pharmacists, hospital managers and patients of changes to Community Pharmaceutical subsidies and the prices for Hospital Pharmaceuticals. In making decisions about amendments to the Pharmaceutical Schedule, PHARMAC is guided by its Operating Policies and Procedures, as amended or supplemented from time to time. PHARMAC takes into account the following criteria when making decisions about Community Pharmaceuticals: G the health needs of all eligible people within New Zealand (eligible deﬁned by the Government’s then current rules of eligibility); G the particular health needs of M¯ ori and Paciﬁc peoples; a G the availability and suitability of existing medicines, therapeutic medical devices and related products and related things; G the clinical beneﬁts and risks of pharmaceuticals; G the cost-effectiveness of meeting health needs by funding pharmaceuticals rather than using other publicly funded health and disability support services; G the budgetary impact (in terms of the pharmaceutical budget and the Government’s overall health budget) of any changes to the Pharmaceutical Schedule; G the direct cost to health service users;

the Government’s priorities for health funding, as set out in any objectives notiﬁed by the Crown to PHARMAC, or in PHARMAC’s Funding Agreement, or elsewhere; and G such other criteria as PHARMAC thinks ﬁt. PHARMAC will carry out appropriate consultation when it intends to take any such “other criteria” into account. The Operating Policies and Procedures, including any supplements, also describe the way in which PHARMAC determines the level of subsidy or purchase price payable for each Community Pharmaceutical or Hospital Pharmaceutical, respectively. The decision criteria for Hospital Pharmaceuticals are set out in the hospital supplement to the Operating Policies and Procedures and in the introductory part of Section H of the Pharmaceutical Schedule. Copies of PHARMAC’s Operating Policies and Procedures and of any applicable supplements are available on the PHARMAC website (www.pharmac.govt.nz), or on request.

PHARMAC and the Pharmaceutical Schedule:

PHARMAC manages the national Pharmaceutical Schedule, which lists: G Pharmaceuticals available in the community and subsidised by the Government with funding from the Pharmaceutical Budget; and G some Pharmaceuticals purchased by DHBs for use in their hospitals, and includes those Hospital Pharmaceuticals for which national prices have been negotiated by PHARMAC. In the community approximately 1848 Pharmaceuticals are subsidised by the Government. Most are available to all eligible people within New Zealand on prescription by a medical doctor. Some are listed with guidelines or conditions such as ‘only if prescribed for a dialysis patient’ or ‘Special Authority - Retail Pharmacy’, to ensure that Pharmaceuticals are used by those people who are most likely to beneﬁt from them. Pharmaceuticals provided to patients for use while in DHB hospitals are not covered by Sections A to G of the Pharmaceutical Schedule. Section H of the Pharmaceutical Schedule is not a comprehensive list of Pharmaceuticals that are used within the DHB Hospitals. Section H of the Pharmaceutical Schedule includes Pharmaceuticals that can be purchased at a national price by DHBs for use in their hospitals. These are referred to as National Contract Pharmaceuticals. A list of Discretionary Community Supply Pharmaceuticals, in Section H of the Pharmaceutical Schedule, identiﬁes those products that currently are not subsidised from the Pharmaceutical Budget as Community Pharmaceuticals in Sections A to G of the Pharmaceutical Schedule but which DHBs can at their discretion fund for use in the community from their own budgets without speciﬁc Hospital Exceptional Circumstances approval.

PHARMAC’s clinical advisors Pharmacology and Therapeutics Advisory Committee (PTAC) PHARMAC works closely with the Pharmacology and Therapeutics Advisory Committee (PTAC), an expert medical committee which provides independent advice to PHARMAC on health needs and the clinical beneﬁts of particular pharmaceuticals for use in the community and/or in DHB Hospitals. The committee members are all senior, practising clinicians. The chair of PTAC sits with the PHARMAC Board in an advisory capacity. PTAC helps decide which community pharmaceuticals are to be subsidised from public monies by making recommendations to PHARMAC. Part of the role of PTAC is to review whether Community Pharmaceuticals already listed on the Schedule should continue to receive Government funds. The resources freed up can be used to subsidise other community pharmaceuticals with a greater therapeutic worth. PHARMAC may obtain clinical advice from PTAC in relation to national purchasing strategies for Hospital Pharmaceuticals. There may be additional specialist hospital representatives on PTAC subcommittees, or additional PTAC subcommittees, where PHARMAC considers this necessary. PTAC members are: Carl Burgess Howard Wilson Chris Cameron Melissa Copland Stuart Dalziel Ian Hosford Sisira Jayathissa George Laking Dee Mangin Graham Mills Mark Weatherall MBChB, MD, MRCP (UK), FRACP, FRCP, physician/clinical pharmacologist, Chair BSc, PhD, MB, BS, Dip Obst, FRNZCGP, FRAGCP Deputy Chair MBChB, FRACP, MClin Pharm PhD, BPharm(Hons), RegPharmNZ, FNZCP MBChB, PhD, FRACP MBChB, FRANZCP, psychiatrist MMedSc (Clin Epi), MMBS, MD, MRCP (UK), FRCP (Edin), FRACP, FAFPHM, Dip Clin Epi, Dip OHP, Dip HSM, MBS PhD, MD, FRACP MBChB, DPH, RNZCGP MBChB, MTropHlth, MD, FRACP, infectious disease specialist and general physician BA, MBChB, MApplStats, FRACP

Contact PTAC C/-Advisory Committee Manager , Pharmaceutical Management Agency, PO Box 10 254, WELLINGTON, Email: PTAC@pharmac.govt.nz PHARMAC’s consumer advisors Consumer Advisory Committee (CAC) The Consumer Advisory Committee is an advisory committee to the PHARMAC Board. It provides written reports to the Board, and its Chair attends Board meetings as an observer to report on the activities and ﬁndings of the Committee, and to comment on consumer issues. While accountable to the Board, the Committee’s general working relationship is with the staff of PHARMAC. The Committee is made up of people from a range of backgrounds and interests including the health of M¯ ori people, Paciﬁc a peoples, older people, women and mental health. For current membership of the Consumer Advisory Committee, visit our website. The Consumer Advisory Committee can be contacted by email: CAC@pharmac.govt.nz, or you can write to the Consumer Advisory Committee at PHARMAC’s postal address.

The PHARMAC Team The PHARMAC team has a wide range of expertise in health, medicine, economics, commerce, critical analysis, and policy development and implementation. Steffan Crausaz Acting Chief Executive Donna Jennings Schedule Analyst Paul Alexander Health Economist Marcus Kim Tender Analyst Richard Anderson Network and Systems Helen Knight Accounts Payable Co-ordinator Administrator Geoff Lawn Applications Developer / Team Leader IT Katie Appleby Community and Cancer Exceptional Circumstances Bridget Macfarlane Access and Optimal Use Panel Co-ordinator Programme Manager Jason Arnold Team Leader, Analysis Janet Mackay Access & Optimal Use Graham Beever General Counsel Programme Manager Diana Beswetherick HR Manager Rachel Mackay Manager, Schedule and Rebecca Bloor Schedule Analyst Contracts Stephen Boxall Creative Director Trish Mahoney Contract Manager Lisa Buxton Senior Receptionist Scott Metcalfe Chief Advisor Population Davina Carpenter Records Manager Medicine / Public Health Angela Cathro M¯ ori Health Programmes’ a Physician Assistant Peter Moodie Medical Director Christine Chapman Therapeutic Group Manager Christina Newman Executive Assistant to Chief Mary Chesterﬁeld High Cost Drugs Co-ordinator Executive & Board Secretary Andrew Davies Acting Manager, Funding and Deborah Nisbet Receptionist Procurement Hew Norris Analyst Natalie Davis Therapeutic Group Manager Leigh Parish PA to Medical Director Rachelle Davies Ofﬁce Manager & HR Marama Parore Manager, Access & Optimal Administrator Use & M¯ ori Health a Jessica Dougherty Corporate Team Executive Chris Peck Analyst Assistant Matthew Poynton Analyst/Health Economist Sean Dougherty Funding Systems Development Dilky Rasiah Deputy Medical Director Manager Awhimai Reynolds M¯ ori Health Manager a Anrik Drenth Web Developer Alexander Rodgers Health Economist Kim Ellis Access & Optimal Use Brian Roulston Contract Manager Co-ordinator Fiona Rutherford Senior Policy Analyst Rico Schoeler Manager, Analysis and Simon England Communications Manager Assessment Jackie Evans Senior Therapeutic Group Manager Carsten Schousboe Health Economist Merryn Simmons PHARMAC Seminar Series John Geering Systems Architect Co-ordinator Anne Glennie Hospital Exceptional Circumstances Panel Liz Skelley Finance Manager Co-ordinator Jude Urlich Manager, Corporate and External Relations Lauren Gooley Funding and Procurement Assistant Jayne Watkins Team Leader, Medical Team Rachel Werner Health Economist Rochelle Harker PTAC Secretary & Panel Bryce Wigodsky Policy Analyst Co-ordinator Greg Williams Therapeutic Group Manager David Harland Health Economist Lisa Williams Legal Counsel Ben Healey Analyst Kaye Wilson Senior Schedule Analyst Hayden Holmes Panel Co-ordinator (Growth Stephen Woodruffe Therapeutic Group Manager Hormone/PAH) Sue Anne Yee Therapeutic Group Manager Karen Jacobs Access & Optimal Use Michael Young Analyst Programme Manager

Purpose of the Pharmaceutical Schedule

The purpose of the Schedule is to list: G the Community Pharmaceuticals that are subsidised by the Government and to show the amount of the subsidy paid to contractors, as well as the manufacturer’s price (if it differs from the Subsidy) and any access conditions that may apply; and G some Hospital Pharmaceuticals that are purchased and used by DHB Hospitals, including those for which national prices have been negotiated by PHARMAC. The purpose of the Schedule is not to show the ﬁnal cost to Government of subsidising each Community Pharmaceutical or to DHBs in purchasing each Hospital Pharmaceutical since that will depend on any rebate and other arrangements PHARMAC has with the supplier and, for some Hospital Pharmaceuticals, on any logistics arrangements put in place by individual DHB Hospitals.

Finding Information in the Pharmaceutical Schedule

Community Pharmaceuticals For Community Pharmaceuticals, the Schedule is organised in a way to help the reader ﬁnd Community Pharmaceuticals, which may be used to treat similar conditions. To do this, Community Pharmaceuticals are ﬁrst classiﬁed anatomically, originally based on the Anatomical Therapeutic Chemical (ATC) system, and then further classiﬁed under section headings structured for the New Zealand medical system. G Section A lists the General Rules in relation to Community Pharmaceuticals and related products. G Section B lists Community Pharmaceuticals and related products by anatomical classiﬁcation, which are further divided into one or more therapeutic headings. Community Pharmaceuticals used to treat similar conditions are grouped together. G Section C lists the rules in relation to Extemporaneously Compounded Products (ECPs) and Community Pharmaceuticals that will be subsidised when extemporaneously compounded. G Section D lists the rules in relation to Special Foods and the Special Foods that are subsidised. G Section E Part I lists the Community Pharmaceuticals that are subsidised on a Practitioner’s Supply Order (PSO). G Section E Part II lists rural areas for the purpose of PSOs. G Section F lists the Community Pharmaceuticals dispensing period exemptions. G Section G lists the Community Pharmaceuticals eligible for reimbursement of safety cap and related rules. The listings are displayed alphabetically (where practical) within each level of the classiﬁcation system. Each anatomical section contains a series of therapeutic headings, some of which may contain a further classiﬁcation level. Where a Community Pharmaceutical is used in more than one therapeutic area, they may be cross-referenced. The therapeutic headings in the Pharmaceutical Schedule do not necessarily correspond to the therapeutic groups and therapeutic subgroups, which PHARMAC establishes for the separate purpose of determining the level of subsidy to be paid for each Community Pharmaceutical. The index located at the back of the book in which Sections A-G of the Pharmaceutical Schedule are published can be used to ﬁnd page numbers for generic chemical entities, or product brand names.

Hospital Pharmaceuticals

Section H lists Pharmaceuticals that DHBs fund from their own budgets. The Hospital Pharmaceuticals are grouped into the following Parts in Section H: G Part I lists the rules in relation to Hospital Pharmaceuticals. G Part II lists Hospital Pharmaceuticals for which national contracts exist (National Contract Pharmaceuticals). These are listed alphabetically by generic chemical entity name and line item, the relevant Price negotiated by PHARMAC and, if applicable, an indication of whether it has Hospital Supply Status (HSS) and any associated Discretionary Variance (DV) Pharmaceuticals and DV Limit. G Part III lists Discretionary Community Supply Pharmaceuticals, which are not Community Pharmaceuticals, but which a DHB Hospital can, in its discretion, fund for use in the community from its own budget. The index located at the back of the Section H supplement can be used to ﬁnd page numbers for generic chemical entities, or product brand names, for Hospital Pharmaceuticals.

Explaining drug entries

The Pharmaceutical Schedule lists pharmaceuticals subsidised by the Government, the amount of that subsidy paid to contractors, the supplier’s price and the access conditions that may apply. Example

ANATOMICAL HEADING

Subsidy (Manufacturer’s Price) $ Per Fully Brand or Subsidised Generic Manufacturer

Three months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber. Practitioner’s Supply Order Safety cap reimbursed Conditions of and restrictions on prescribing (including Special Authority where it applies) Three months or six months, as applicable, dispensed all-at-once

THERAPEUTIC HEADING CHEMICAL L Presentation, form and strength .........................10.00

100

Brand A Brand B Brand C Brand D Brand or manufacturer’s name Sole subsidised supply product Fully subsidised product Original Pack Subsidy is rounded up to a multiple of whole packs

Presentation - Available on a PSO .....................15.00 ‡ Presentation - Retail pharmacy-specialist ..........18.00 a) Prescriptions must be written by a paediatrician or paediatric cardiologist; or b) on the recommnedation of a paediatrician or a paediatric cardiologist CHEMICAL F Presentation, form and strength .........................26 26.53 (35.27)

50 250 ml OP

100 Brand E

Quantity the Subsidy applies to Subsidy paid on a product before mark-ups and GST Manufacturer’s Price if different from Subsidy

Sole Supply Fully Subsidised

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the presriber.

Glossary

Units of Measure gram ..................................................g kilogram...........................................kg international unit ...............................iu microgram........................................µg milligram .........................................mg millilitre.............................................ml millimole......................................mmol unit.....................................................u

Abbreviations Ampoule ...................................... Amp Granules ......................................Gran Suppository ................................ Supp Capsule ........................................ Cap Infusion............................................Inf Tablet .............................................Tab Cream...........................................Crm Injection ...........................................Inj Tincture.........................................Tinc Device........................................... Dev Linctus .......................................... Linc Trans Dermal Delivery Dispersible................................... Disp Liquid..............................................Liq System.................................. TDDS Effervescent.................................... Eff Long Acting..................................... LA Emulsion..................................... Emul Ointment....................................... Oint Enteric Coated................................EC Sachet ........................................ Sach Gelatinous ..................................... Gel Solution........................................ Soln BSO Bulk Supply Order. CBS Cost Brand Source. There is no set manufacturer’s price, and the Government subsidises the product at the price it is obtained by the pharmacy. CE Compounded Extemporaneously. CPD Cost Per Dose. The Funder (as deﬁned in Part I of the General Rules) cost of a standard dose, without mark-ups or fees and excluding GST. ECP Extemporaneously Compounded Preparation. HSS Hospital Supply Status, the status of being the brand of the relevant Hospital Pharmaceutical listed in Section H Part II as HSS, that DHBs are obliged to purchase subject to any DV Limit for that Hospital Pharmaceutical for the period of hospital supply, as awarded under an agreement between PHARMAC and the relevant pharmaceutical supplier. OP Original Pack – subsidy is rounded up to a multiple at whole packs. PSO Practitioner’s Supply Order. Sole Subsidised Supplier Only brand of this medicine subsidised. XPharm Pharmacies cannot claim subsidy because PHARMAC has made alternative distribution arrangements. L Three months supply may be dispensed at one time if the exempted medicine is endorsed ‘certiﬁed exemption’ by the practitioner. F Three months dispensed all-at-once or, in the case of oral contraceptives, six months dispensed all-at-once, unless medicine is endorsed “close control” or “cc” and the endorsement is initialled by the prescriber. ‡ Safety cap required and subsidised for oral liquid formulations, including extemporaneously compounded preparations. Fully subsidised brand of a given medicine. Brands without the tick are not fully subsidised and may cost the patient a manufacturer’s surcharge. S29 This medicine is an unapproved medication supplied under Section 29 of the Medicines Act 1981. Practitioners prescribing this medication should: a) be aware of and comply with their obligations under Section 29 of the Medicines Act 1981 and otherwise under that Act and the Medicines Regulations 1984; b) be aware of and comply with their obligations under the Health and disability Commissioner’s Code of Consumer Rights, including the requirement to obtain informed consent from the patient (PHARMAC recommends that Practitioners obtain written consent); and c) exercise their own skill, judgement, expertise and discretions, and make their own prescribing decisions with respect to the use of an unapproved Pharmaceutical or a Pharmaceutical for an indication for which it is not approved. Note: Where medicines supplied under Section 29 that are used for emergency situations, patient details required under Section 29 of the Medicines Act may be retrospectively provided to the supplier.

Abbrev. [HP3]

[HP4]

Deﬁnitions Pharmacy Services Agreement Subsidised when dispensed from pharmacies that have a Special Foods Service appended to their Pharmacy Services Agreement by their DHB. Subsidised when dispensed from pharmacies that have the Monitored Therapy Variation (for Clozapine Services)

All other Pharmacy Agreements Available from selected pharmacies that have an exclusive contract to dispense Special Foods. Avaliable from selected pharmacies that have an exclusive contract to dispense ‘Hospital Pharmacy’ [HP4] pharmaceuticals.

Patient costs

Community Pharmaceuitical costs met by the Government Most of the cost of a subsidised prescription Community Pharmaceutical is met by the Government through the Pharmaceutical Budget. The Government pays a subsidy for the Community Pharmaceutical to Contractors, and a fee covering distribution and pharmacy dispensing services. The subsidy paid to Contractors does not necessarily represent the ﬁnal cost to Government of subsidising a particular Community Pharmaceutical. The ﬁnal cost will depend on the nature of PHARMAC’s contractual arrangements with the supplier. Fully subsidised medicines are identiﬁed with a in the product’s Schedule listing. SALBUTAMOL Aerosol inhaler 100 µg per dose....................................... 3.80 (6.00) Fully subsidised brand Higher priced brand

Pharmaceutical Co-Payments Some Community Pharmaceutical costs are met by the patient. Generally a patient pays a prescription charge. In addition a patient will sometimes pay a manufacturer’s surcharge, after hours service fee and any special packaging fee. PRESCRIPTION CHARGE From 1 September 2008, everyone who is eligible for publicly funded health and disability services should in most circumstances pay only $3 for subsidised medicines. All prescriptions from a public hospital, a midwife and a Family Planning Clinic are covered for $3 co-payments. Prescriptions from the following providers are approved for $3 co-payments on subsidised medicines if they meet the speciﬁed criteria: G After Hours Accident and Medical Services with a DHB or a PHO contract. G Youth Health Clinics with a DHB or a PHO contract. G Dentists who write a prescription that relates to a service being provided under a DHB contract. G Private specialists (for example, opthalmologists and orthopaedics) who write a prescription for a patient receiving a publicly funded service contracted by the DHB. G General practitioners who write a prescription during normal business hours to a person who is not enrolled in the general practice provided the person is eligible for publicly funded health and disability services and the general practice is part of a PHO. G Hospices that have a contract with a DHB. Patients can check whether they are eligible for publicly funded health and disability services by referring to the Eligibility Direction on the Ministry of Health’s website. To check if a medicine is fully subsidised, refer to the Pharmaceutical Schedule on PHARMAC’s website or ask your pharmacist or general practitioner. DHBs have a list of eligible providers in their respective regions. Any provider/prescriber not speciﬁcally listed by a DHB as an approved provider/prescriber should be regarded as not approved. NOTE: Information sourced from Ministry of Health Website, for more information please visit www.moh.govt.nz MANUFACTURER’S SURCHARGE Not all Community Pharmaceuticals are fully subsidised. Although PHARMAC endeavours to fully subsidise at least one Community Pharmaceutical in each therapeutic group, and has contracts with some suppliers to maintain the price of a particular product, manufacturers are able to set their own price to pharmacies. When these prices exceed the subsidy, the pharmacist may recoup the difference from the patient. To estimate the amount a patient will pay on top of the prescription charge, take the difference between the manufacturer’s price and the subsidy, and multiply this by 1.86. The 1.86 factor represents the pharmacy mark-up on the surcharge plus other costs such as GST. Pharmacies charge different mark-ups so this may vary. Manufacturer’s surchage to patient = (price − subsidy) × 1.86 For example, a Community Pharmaceutical with a supplier (ex-manufacturer) cost of $11.00 per pack with a $10.00 subsidy will cost the patient a surchage of $1.86 on top of the prescription charge. The most a patient should pay is therefore $16.86 - being

$15.00 maximum prescription charge, plus $1.86. Hospital Pharmaceutical and Pharmaceutical Cancer Treatment Costs The cost of purchasing Hospital Pharmaceuticals (for use in DHB hospitals and/or in association with Outpatient services provided in DHB hospitals) is met by the relevant DHB hospital Funder from its own budget. Pharmaceutical Cancer Treatments (for use in DHB hospitals and/or in association with Outpatient services provided in DHB hospitals) are funded through the Combined Pharmaceutical Budget. As required by section 23(7) of the Act, in performing any of their functions in relation to the supply of Pharmaceuticals including Pharmaceutical Cancer Treatments, DHBs must not act inconsistently with the Pharmaceutical Schedule. PHARMAC web site PHARMAC has set up an interactive Schedule on the Internet. Other information about PHARMAC is also available on our website. This includes copies of the Annual Review, Annual Report and Annual Plan, as well as information such as the Pharmaceutical Schedule, Pharmaceutical Schedule Updates, National Hospital Pharmaceutical Strategy, other publications and recent press releases.

Special Authority Applications

Special Authority is an application process in which a prescriber requests government subsidy on a Community Pharmaceutical for a particular person. Applications must be submitted to the Ministry of Health by the prescriber for the request to be processed. Subsidy Once approved, the presciber will be provided a Special Authority number which must appear on the prescription. Specialists who make an application must communicate the valid authority number to the prescriber who will be writing the prescriptions. The authority number can provide access to subsidy, increased subsidy, or waive certain restrictions otherwise present on the Community Pharmaceutical. Some approvals are dependent on the availability of funding from the Pharmaceutical Budget. Criteria The criteria for approval of Special Authority applications are included below each Community Pharmaceutical listing, and on the application forms available on PHARMAC’s website. For some Special Authority Community Pharmaceuticals, not all indications that have been approved by Medsafe are subsidised. Criteria for each Special Authority Community Pharmaceutical are updated regularly, based on the decision criteria of PHARMAC. The appropriateness of the listing of a Community Pharmaceutical in the Special Authority category will also be regularly reviewed. Applications for inclusion of further Community Pharmaceuticals in the Special Authority category will generally be made by a pharmaceutical supplier. Special Authority Applications Application forms can be found at www.pharmac.govt.nz. Requests for fax copies should be made to PHARMAC, phone 04 460 4990. Applications are processed by the Ministry of Health, and should be sent to: Ministry of Health Sector Services, Fax: (06) 349 1983 or free fax 0800 100 131 Private Bag 3015, WANGANUI 4540 For enquiries, phone the Ministry of Health Sector Services Call Centre, free phone 0800 243 666 Note: The Ministry of Health can only provide information on Special Authority applications to prescribers and pharmacists. Each application must: G Include the patients name, date of birth and NHI number (codes for AIDS patients’ applications) G Include the practitioner’s name, address and Medical Council registration number G Clearly indicate that the relevant criteria, have been met. G Be signed by the practitioner.

Exceptional Circumstances policies

The purpose of the Exceptional Circumstances policies are to provide: G funding from within the Pharmaceutical Budget for medication, to be used in the community, in circumstances where the provision of a funded community medication is appropriate, but funding from the Pharmaceutical Budget is not able to be provided through the Pharmaceutical Schedule (“Community Exceptional Circumstances”); or G an assessment process for the DHB Hospitals to determine whether they can fund medication, to be used in the community, in circumstances where the medication is neither a Community Pharmaceutical nor a Discretionary Community Supply Pharmaceutical and where the patient does not meet the criteria for Community Exceptional Circumstances (“Hospital Exceptional Circumstances”); or G funding from the Pharmaceutical Budget for pharmaceuticals for the treatment of cancer in their DHB Hospital, or in association with Outpatient services provided in their DHB hospital, in circumstances where the pharmaceutical is not identiﬁed as a Pharmaceutical Cancer Treatment (“Cancer Exceptional Circumstances”) in Sections A-H of the Pharmaceutical Schedule. Upon receipt of an application for approval for Community Exceptional Circumstances or Hospital Exceptional Circumstances, the Exceptional Circumstances Panel ﬁrst decides whether an application will be assessed initially under the Community Exceptional Circumstances criteria or the Hospital Exceptional Circumstances criteria. Cancer Exceptional Circumstances is a separate process.

Hospital Exceptional Circumstances

If the application is ﬁrst assessed but not approved under the Community Exceptional Circumstances criteria, the Exceptional Circumstances Panel may recommend the funding of the pharmaceutical for use in the community by a speciﬁc patient from a DHB Hospital’s own budget under Hospital Exceptional Circumstances. If the application is ﬁrst assessed under the Hospital Exceptional Circumstances criteria, the Exceptional Circumstances Panel may: a) recommend against the funding of the pharmaceutical for use in the community by a speciﬁc patient from a DHB Hospital’s own budget, in which case a DHB Hospital must not fund the pharmaceutical from its own budget; b) recommend the funding of the pharmaceutical for use in the community by a speciﬁc patient from a DHB Hospital’s own budget under Hospital Exceptional Circumstances, in which case a DHB Hospital may, but is not obliged to, fund the pharmaceutical from its own budget; c) defer its decision until further assessment under the Community Exceptional Circumstances criteria can undertaken; or d) recommend interim funding of the pharmaceutical for use in the community by a speciﬁc patient from a DHB Hospital’s own budget under Hospital Exceptional Circumstances until further assessment under the Community Exceptional Circumstances criteria can be undertaken. Permission to fund a pharmaceutical for use in the community by a speciﬁc patient from a DHB Hospital’s own budget under Hospital Exceptional Circumstances will only be granted by PHARMAC where it has been demonstrated that such funding is cost-effective for the relevant DHB in the region in which the patient resides. If the patient being treated with a pharmaceutical under Hospital Exceptional Circumstances usually resides in a district other than that within the jurisdiction of the DHB initiating the treatment, then the DHB initiating the treatment must either agree to fund any on-going treatment required once the patient has returned to his/her usual DHB, or obtain written consent from the DHB or DHBs in which the patient will reside following the commencement of treatment. Applications for Hospital Exceptional Circumstances should be made on the standard application form available from the PHARMAC website www.pharmac.govt.nz or the address below: The Coordinator, Hospital Exceptional Circumstances Panel Phone: (04) 916 7521 PHARMAC, PO Box 10 254 or fax (09) 523 6870 Wellington Email: ecpanel@pharmac.govt.nz

Cancer Exceptional Circumstances

Permission to fund a pharmaceutical for the treatment of cancer under Cancer Exceptional Circumstances will only be granted by PHARMAC where it has been demonstated that the proposed use meets the criteria.

Community Exceptional Circumstances

In order to qualify for Community Exceptional Circumstances approval one of the following criteria must be met: a) the condition must be rare; or b) the reaction to alternative funded treatment must be unusual; or c) an unusual combination of circumstances applies. Rare and unusual are considered to be in the order of less than 10 people nationally. Where one of the above Community Exceptional Circumstances entry criteria is met, the application may then be further examined under supplementary criteria, assessing suitability of the pharmaceutical, clinical beneﬁt, the cost effectiveness of the treatment, and the patient’s ability to pay for the treatment. Where these documented criteria are met, a subsidy sufﬁcient to fully fund the pharmaceutical will be made available to the speciﬁc patient on whose behalf the application was made. Community Exceptional Circumstances funding is only available where the criteria are met and is not available for ﬁnancial reasons alone. Applications for Community Exceptional Circumstances, Hospital Exceptional Circumstances and Cancer Exceptional Circumstances should be made on the standard application form available from the PHARMAC website www.pharmac.govt.nz or the address below: The Coordinator, Community Exceptional Circumstances Panel Phone (04) 916 7553 PO Box 10 254 or fax (09) 523 6870 Wellington Email: ecpanel@pharmac.govt.nz

SECTION A: GENERAL RULES

INTRODUCTION

Section A contains the restrictions and other general rules that apply to Subsidies on Community Pharmaceuticals. The amounts payable by the Funder to Contractors are currently determined by: G the quantities, forms, and strengths, of subsidised Community Pharmaceuticals dispensed under valid prescription by each Contractor; G the amount of the Subsidy on the Manufacturer’s Price payable for each unit of the Community Pharmaceuticals dispensed by each Contractor and; G the contractual arrangements between the Contractor and the Funder for the payment of the Contractor’s dispensing services. The Pharmaceutical Schedule shows the level of subsidy payable in respect of each Community Pharmaceutical so that the amount payable by the Government to Contractors, for each Community Pharmaceutical, can be calculated. The Pharmaceutical Schedule also shows the standard price (exclusive of GST) at which a Community Pharmaceutical is supplied ex-manufacturer to wholesalers if it differs from the subsidy. The manufacturer’s surcharge to patients can be estimated using the subsidy and the standard manufacturer’s price as set out in this Schedule. The cost to Government of subsidising each Community Pharmaceutical and the manufacturer’s prices may vary, in that suppliers may provide rebates to other stakeholders in the primary health care sector, including dispensers, wholesalers, and the Government. Rebates are not speciﬁed in the Pharmaceutical Schedule. This Schedule is dated 1 December 2011 and is to be referred to as the Pharmaceutical Schedule Volume 18 Number 3, 2011. Distribution will be from 20 December 2011. This Schedule comes into force on 1 December 2011.

PART I INTERPRETATIONS AND DEFINITIONS

1.1 In this Schedule, unless the context otherwise requires: “90 Day Lot” means the quantity of a Community Pharmaceutical required for the number of days’ treatment covered by the Prescription, being up to 90 consecutive days’ treatment; “180 Day Lot” means the quantity of a Community Pharmaceutical required for the number of days’ treatment covered by the Prescription, being up to 180 consecutive days’ treatment; “Access Exemption Criteria” means the criteria under which patients may receive greater than one Month’s supply of a Community Pharmaceutical covered by Section F Part II (b) subsidised in one Lot. The speciﬁcs of these criteria are conveyed in the Ministry of Health guidelines, which are issued from time to time. The criteria the patient must meet are that they: a) have limited physical mobility; b) live and work more than 30 minutes from the nearest pharmacy by their normal form of transport; c) are relocating to another area; d) are travelling extensively and will be out of town when the repeat prescriptions are due. “Act” means the New Zealand Public Health and Disability Act 2000. “Advisory Committee” means the Pharmaceutical Services Advisory Committee convened by the Ministry of Health under the terms of the Advice Notice issued to Contractors pursuant to Section 88 of the Act. “Alternate Subsidy” means a higher level of subsidy that the Government will pay contractors for a particular community Pharmaceutical dispensed to a person who has either been granted a Special Authority for that pharmaceutical, or where the prescription is endorsed in accordance with the requirements of this Pharmaceutical Schedule. “Annotation” means written annotation of a prescription by a dispensing pharmacist in the pharmacist’s own handwriting following conﬁrmation from the Prescriber if required, and “Annotated” has a corresponding meaning. The Annotation must include the details speciﬁed in the Schedule, including the date the prescriber was contacted (if applicable) and be initialled by the dispensing pharmacist. “Assessed Pharmaceuticals” means the list of Pharmaceuticals set out in Section H Part III of the Schedule, that have been or are being assessed by PHARMAC. “Authority to Substitute” means an authority for the dispensing pharmacist to change a prescribed medicine in accordance with regulation 42(4) of the Medicines Regulations 1984. An authority to substitute letter, which may be used by Practitioners, is available on the ﬁnal page of the Schedule. “Bulk Supply Order” means a written order, on a form supplied by the Ministry of Health, or approved by the Ministry of Health, made by the licensee or manager of an institution certiﬁed to provide hospital care under the Health and Disability

SECTION A: GENERAL RULES

Services (Safety) Act 2001 for the supply of such Community Pharmaceuticals as are expected to be required for the treatment of persons who are under the medical or dental supervision of such a Private Hospital or institution. “Cancer Exceptional Circumstances” means the policies and criteria administered by PHARMAC relating to the ability to fund, pharmaceuticals for the treatment of cancer that are not identiﬁed as Pharmaceutical Cancer Treatments in Sections A-H of the Pharmaceutical Schedule. “Class B Controlled Drug” means a Class B controlled drug within the meaning of the Misuse of Drugs Act 1975. “Close Control” means dispensing: G in quantities less than one 90 Day Lot (or for oral contraceptives, less than one 180 Day Lot) for a Community Pharmaceutical referred to in Section F Part I, or G in quantities less than a Monthly Lot for any other Community Pharmaceutical, where any of A), or B) or C) apply. G This Close Control rule deﬁnes patient groups or medicines which are eligible for more frequent dispensing periods and the conditions that must be met to enable any claim for payment for additional dispensing to be made. A) Frequency of dispensing for persons in residential care Pharmaceuticals can be dispensed in quantities of not less than 28 days to: G any person whose placement in a Residential Disability Care institution is funded by the Ministry of Health or a DHB; or G a person assessed as requiring long term residential care services and residing in an age related residential care facility; on the request of the person, their agent or caregiver or community residential service provider, provided the following conditions are met: i) the quantity or period of supply to be dispensed at any one time is not less than 28 days’ supply (except under conditions outlined in B.i below); and ii) the prescribing Practitioner or dispensing pharmacist has 1) included the name of the patient’s residential placement or facility on the prescription; and 2) included the patient’s NHI number on the prescription; and 3) speciﬁed the maximum quantity or period of supply to be dispensed at any one time. Any person meeting the criteria above who is being initiated onto a new medicine or having their dose changed is able to have their medicine dispensed in accordance with B.i below. B) Flexible periods of supply for trial periods or safety The Schedule speciﬁes for community patients a default length of dispensing (monthly/three monthly) for each pharmaceutical. Prescribers can request, and pharmacists may dispense, a higher frequency of dispensing in the following circumstances: If the prescribing Practitioner has met the prescribing conditions set out in B.iii below, and the pharmaceutical or patient ﬁts within the provisions of B.i and B.ii below, a pharmacist may dispense more frequently than the Schedule default period of supply. i) Trial Periods The Community Pharmaceutical has been prescribed for a patient who requires close monitoring due to recent initiation onto, or dose change for, the Community Pharmaceutical (applicable to the patient’s ﬁrst changed Prescription only); or ii) Safety 1) the Community Pharmaceutical is any of the following: a) a tri-cyclic antidepressant; or b) an antipsychotic; or c) a benzodiazepine; or d) a Class B Controlled Drug; or 2) The Community Pharmaceutical has been prescribed for a patient who: a) is not a resident in a Penal Institution, or one of the residential placements or facilities referenced in clause A above; and b) in the opinion of the prescribing Practitioner, is intellectually impaired or frail, inﬁrm or unable to manage their medicine without additional support. For B.i and B.ii all of the following conditions must be met: iii) The prescribing Practitioner has:

SECTION A: GENERAL RULES

1) endorsed each Community Pharmaceutical on the Prescription clearly with the words “Close Control” or “CC”; and 2) initialled the endorsement in their own handwriting; and 3) speciﬁed the maximum quantity or period of supply to be dispensed at any one time. 4) For trial periods each Community Pharmaceutical on the Prescription must be endorsed with either “Close Control Trial” or “CCT” and the period of supply included e.g. CC Trial 1 week. C) Pharmaceutical Supply Management More frequent dispensing may be required from time to time to manage stock supply issues or emergency situations. Pharmacists may dispense more frequently than the Schedule would otherwise allow when all of the following conditions are met: i) PHARMAC has approved and notiﬁed pharmacists to annotate prescriptions for a speciﬁed Community Pharmaceutical(s) “Close Control” without prescriber endorsement for a speciﬁed time; and ii) the dispensing pharmacist has: 1) clearly annotated each of the approved Community Pharmaceuticals that appear on the prescription with the words “Close Control” or “CC”; and 2) initialled the annotation in their own handwriting; and 3) has complied with maximum quantity or period of supply to be dispensed at any one time, as speciﬁed by PHARMAC at the time of notiﬁcation. If a dispensing frequency is expressly stated in the Medicines Act, Medicines Regulations or Pharmacy Services Agreement a pharmacy can dispense at that speciﬁed dispensing frequency. However, no claim shall be made to any DHB for subsidised payment for dispensing fees in any case where dispensing occurs more frequently than authorised by the provisions of the Schedule. “Community Exceptional Circumstances” means the policies and criteria administered by the Exceptional Circumstances Panel relating to funding from the Community Exceptional Circumstances budget for medication, to be used in the community, in circumstances where the provision of a funded community medication is appropriate, but funding from the Pharmaceutical Budget is not able to be provided through the Pharmaceutical Schedule. “Community Pharmaceutical” means a Pharmaceutical listed in Sections A to G of the Pharmaceutical Schedule that is subsidised by the Funder from the Pharmaceutical Budget for use in the community. “Contractor” means a person who is entitled to receive a payment from the Crown or a DHB under a notice issued by the Crown or a DHB under Section 88 of the Act or under a contract with the Ministry of Health or a DHB for the supply of Community Pharmaceuticals. “Controlled Drug” means a controlled drug within the meaning of the Misuse of Drugs Act 1975 (other than a controlled drug speciﬁed in Part VI of the Third Schedule to that Act). “Cost, Brand, Source of Supply” means that the Community Pharmaceutical is eligible for Subsidy on the basis of the Contractor’s annotated purchase price, brand, and source of supply. “Dentist” means a person registered with the Dental Council, and who holds a current annual practising certiﬁcate, under the HPCA Act 2003. “Diabetes Nurse Prescriber” means a registered nurse practising in diabetes health who has authority to prescribe speciﬁed diabetes medicines in accordance with regulations made under the Medicines Act 1981, and who is practicing in an approved DHB demonstration site. “Dietitian” means a person registered as a dietitian with the Dietitians Board, and who holds a current annual practicing certiﬁcate under the HPCA Act 2003. “DHB” means an organisation established as a District Health Board by or under Section 19 of the Act. “DHB Hospital” means a DHB, including its hospital or associated provider unit that the DHB purchases Hospital Pharmaceuticals for. “Discretionary Community Supply Pharmaceutical” means the list of Pharmaceuticals set out in Section H Part IV of the Schedule, which may be funded by a DHB Hospital from its own budget for use in the community. “Doctor” means a medical Practitioner registered with the Medical Council of New Zealand and, who holds a current annual practising certiﬁcate under the HPCA Act 2003. “DV Limit” means, for a particular Hospital Pharmaceutical with HSS, the National DV Limit or the Individual DV Limit. “DV Pharmaceutical” means a discretionary variance Pharmaceutical, that does not have HSS and which: a) is either listed in Section H Part II of the Schedule as being a DV Pharmaceutical in association with the relevant Hospital Pharmaceutical with HSS; or

SECTION A: GENERAL RULES

b) is the same chemical entity, at the same strength, and in the same or a similar presentation or form, as the relevant Hospital Pharmaceutical with HSS, but which is not yet listed as being a DV Pharmaceutical. “Endorsements” - unless otherwise speciﬁed, endorsements should be either handwritten or computer generated by the practitioner prescribing the medication. The endorsement can be written as “certiﬁed condition”, or state the condition of the patient, where that condition is speciﬁed for the Community Pharmaceutical in Section B of the Pharmaceutical Schedule. Where the practitioner writes “certiﬁed condition” as the endorsement, he/she is making a declaration that the patient meets the criteria as set out in Section B of the Pharmaceutical Schedule. “Exceptional Circumstances Panel” means the panel of clinicians, appointed by the PHARMAC Board, that is responsible for administering policies in relation to Community Exceptional Circumstances and Hospital Exceptional Circumstances. “Funder” means the body or bodies responsible, pursuant to the Act, for the funding of pharmaceuticals listed on the Schedule (which may be one or more DHBs and/or the Ministry of Health) and their successors. “GST” means goods and services tax under the Goods and Services Tax Act 1985. “Hospital Care Operator” means a person for the time being in charge of providing hospital care, in accordance with the Health and Disability Services (Safety) Act 2001. “Hospital Exceptional Circumstances” means the policies and criteria administered by the Exceptional Circumstances Panel relating to the ability to fund, from a DHB Hospital’s own budget, pharmaceuticals for use in the community by a speciﬁc patient where a subsidy is not available from the Pharmaceutical Budget or under Community Exceptional Circumstances. “Hospital Pharmaceuticals” means National Contract Pharmaceuticals, DV Pharmaceuticals, Discretionary Community Supply Pharmaceuticals and Assessed Pharmaceuticals. “Hospital Pharmacy” means that the Community Pharmaceutical is not eligible for Subsidy unless it is supplied by a hospital or pharmacy contracted to the Funder to dispense as a hospital pharmacy to an person on the Prescription of a Practitioner. “Hospital Pharmacy-Specialist” means that the Community Pharmaceutical is not eligible for Subsidy unless it is supplied by a hospital or pharmacy contracted to the Funder to dispense as a hospital pharmacy to an Outpatient either: a) on a Prescription signed by a Specialist, or b) where the treatment with the Community Pharmaceutical has been recommended by a Specialist, on the Prescription of a practitioner which is either: i) endorsed with the words “recommended by [name of specialist and year of authorisation]” and signed by the Practitioner, or ii) annotated by the dispensing pharmacist, following verbal conﬁrmation from the Practitioner of the name of the Specialist and date of recommendation, with the words “recommended by [name of specialist and date of authorisation], conﬁrmed by [practitioner]”. Where the Contractor has an electronic record of such an Endorsement or Annotation from a previous prescription for the same Community Pharmaceutical written by a prescriber for the same patient, they may annotate the prescription accordingly. “As recommended by a Specialist” to be interpreted as: a) follows a substantive consultation with an appropriate Specialist; b) the consultation to relate to the Patient for whom the Prescription is written; c) consultation to mean communication by referral, telephone, letter, facsimile or email; d) except in emergencies consultation to precede annotation of the Prescription; and e) both the specialist and the General Practitioner must keep a written record of the consultation. For the purposes of the deﬁnition it makes no difference whether or not the Specialist is employed by a hospital. “Hospital Pharmacy-Specialist Prescription” means that the Community Pharmaceutical is not eligible for Subsidy unless it is supplied by a hospital or pharmacy contracted to the Funder to dispense as a hospital pharmacy: a) to an Outpatient; and b) on a Prescription signed by a Specialist. For the purposes of this deﬁnition, a “specialist” means a doctor who holds a current annual practicing certiﬁcate and who satisﬁes the criteria set out in paragraphs (a) or (b) or (c) of the deﬁnitions of Specialist below. “HSS” means hospital supply status, the status of being the brand of the relevant Hospital Pharmaceutical listed in Section H Part II as HSS, that DHBs are obliged to purchase subject to any DV Limit for that Hospital Pharmaceutical for the period of hospital supply, as awarded under an agreement between PHARMAC and the relevant pharmaceutical supplier. “In Combination” means that the Community Pharmaceutical is only subsidised when prescribed in combination with another subsidised pharmaceutical as speciﬁed in Section B or C of the Pharmaceutical Schedule. “Individual DV Limit” means, for a particular Hospital Pharmaceutical with HSS and a particular DHB Hospital, the discretionary variance limit, being the speciﬁed percentage of that DHB Hospital’s Total Market Volume up to which that DHB Hospital may purchase DV Pharmaceuticals of that Hospital Pharmaceutical.

SECTION A: GENERAL RULES

“Licensed Hospital” means a place or institution that is certiﬁed to provide hospital care within the meaning of the Health and Disability Services (Safety) Act 2001. “Lot” means a quantity of a Community Pharmaceutical supplied in one dispensing. “Manufacturer’s Price” means the standard price at which a Community Pharmaceutical is supplied to wholesalers (excluding GST), as notiﬁed to PHARMAC by the supplier. “Maternity hospital” means that the Community Pharmaceutical is not eligible for Subsidy unless it is supplied pursuant to a Bulk Supply Order to a maternity hospital certiﬁed under the Health and Disability Services (Safety) Act 2001. “Midwife” means a person registered as a midwife with the Midwifery Council, and who holds a current annual practising certiﬁcate under the HPCA Act 2003. “Month” means a period of 30 consecutive days. “Monthly Lot” means the quantity of a Community Pharmaceutical required for the number of days’ treatment covered by the Prescription, being up to 30 consecutive days’ treatment; “National Contract Pharmaceutical” means a Hospital Pharmaceutical for which PHARMAC has negotiated a national contract and the Price. “National DV Limit” means, for a particular Hospital Pharmaceutical with HSS, the discretionary variance limit, being the speciﬁed percentage of the Total Market Volume up to which all DHB Hospitals may collectively purchase DV Pharmaceuticals of that Hospital Pharmaceutical. “Not In Combination” means that no Subsidy is available for any Prescription containing the Community Pharmaceutical in combination with other ingredients unless the particular combination of ingredients is separately speciﬁed in Section B or C of the Schedule, and then only to the extent speciﬁed. “Nurse Prescriber” means a nurse registered with the Nursing Council and who holds a current annual practicing certiﬁcate under the HPCA Act 2003 and who is approved by the Nursing Council, to prescribe speciﬁed prescription medicines relating to his/her scope of practice including, for the avoidance of doubt, a Diabetes Nurse Prescriber. “Optometrist” means a person registered as an optometrist with the Optometrists and Dispensing Opticians Board, who holds a current annual practising certiﬁcate under the HPCA Act 2003, and who is authorised by regulations under the Medicines Act 1981 and approved by the Optometrists and Dispensing Opticians Board to prescribe speciﬁed medicines. “Outpatient” , in relation to a Community Pharmaceutical, means a person who, as part of treatment at a hospital or other institution under the control of a DHB, is prescribed the Community Pharmaceutical for consumption or use in the person’s home. “PCT” means Pharmaceutical Cancer Treatment in respect of which DHB hospital pharmacies and other Contractors can claim Subsidies. “PCT only” means Pharmaceutical Cancer Treatment in respect of which only DHB hospital pharmacies can claim Subsidies. “Penal Institution” means a penal institution, as that term is deﬁned in The Penal Institutions Act 1954; “PHARMAC” means the Pharmaceutical Management Agency established by Section 46 of the Act (PHARMAC). “Pharmaceutical” means a medicine, therapeutic medical device, or related product or related thing listed in Sections B to H of the Schedule. “Pharmaceutical Beneﬁts” means the right of: a) a person; and b) any member under 16 years of age of that person’s family, to have made by the Government on his or her behalf, subject to any conditions for the time being speciﬁed in the Schedule, such payment in respect of any Community Pharmaceutical supplied to that person or family member under the order of a Practitioner in the course of his or her practice. “Pharmaceutical Budget” means the pharmaceutical budget set for PHARMAC by the Crown for the subsidised supply of Community Pharmaceuticals and Pharmaceutical Cancer Treatments including for named patients in exceptional circumstances. “Pharmaceutical Cancer Treatment” means Pharmaceuticals for the treatment of cancer, listed in Sections A to G of the Schedule and identiﬁed therein as a “PCT” or “PCT only” Pharmaceutical that DHBs must provide access to, for use in their hospitals, and/or in association with Outpatient services provided in their DHB Hospitals, in relation to the treatment of cancers. “Practitioner” means a Doctor, a Dentist, a Dietitian, a Midwife, a Nurse Prescriber or an Optometrist as those terms are deﬁned in the Pharmaceutical Schedule. “Practitioner’s Supply Order” means a written order made by a Practitioner on a form supplied by the Ministry of Health, or approved by the Ministry of Health, for the supply of Community Pharmaceuticals to the Practitioner, which the Practitioner

SECTION A: GENERAL RULES

requires to ensure medical supplies are available for emergency use, teaching and demonstration purposes, and for provision to certain patient groups where individual prescription is not practicable. “Prescription” means a quantity of a Community Pharmaceutical prescribed for a named person on a document signed by a Practitioner. “Prescription Medicine” means any Pharmaceutical listed in Part I of Schedule 1 of the Medicines Regulations 1984. “Private Hospital” means a hospital certiﬁed under the Health and Disability Services (Safety) Act 2001 that is not owned or operated by a DHB. “Residential Disability Care Institution” means premises used to provide residential disability care in accordance with the Health and Disability Services (Safety) Act 2001. “Rest Home” means premises used to provide rest home care in accordance with the Health and Disability Services (Safety) Act 2001. “Restricted Medicine” means any Pharmaceutical listed in Part II of Schedule 1 of the Medicines Regulations 1984. “Retail Pharmacy-Specialist” means that the Community Pharmaceutical is only eligible for Subsidy if it is either: a) supplied on a Prescription or Practitioner’s Supply Order signed by a Specialist, or, b) in the case of treatment recommended by a Specialist, supplied on a Prescription or Practitioner’s Supply Order and either: i) endorsed with the words “recommended by [name of Specialist and year of authorisation]” and signed by the Practitioner, or ii) Annotated by the dispensing pharmacist, following verbal conﬁrmation from the Practitioner of the name of the Specialist and date of recommendation, with the words “recommended by [name of specialist and year of authorisation], conﬁrmed by [practitioner]”. Where the Contractor has an electronic record of such an Endorsement or Annotation from a previous prescription for the same Community Pharmaceutical written by a prescriber for the same patient, they may annotate the prescription accordingly. “As recommended by a Specialist” to be interpreted as: a) follows a substantive consultation with an appropriate Specialist; b) the consultation to relate to the Patient for whom the Prescription is written; c) consultation to mean communication by referral, telephone, letter, facsimile or email; d) except in emergencies consultation to precede annotation of the Prescription; and e) both the Specialist and the General Practitioner must keep a written record of consultation. “Retail Pharmacy-Specialist Prescription” means that the Community Pharmaceutical is only eligible for Subsidy if it is supplied on a Prescription, or Practitioner’s Supply Order, signed by a Specialist. For the purposes of this deﬁnition, a “specialist” means a doctor who holds a current annual practicing certiﬁcate and who satisﬁes the criteria set out in paragraphs (a) or (b) or (c) of the deﬁnitions of Specialist below. “Schedule” means this Pharmaceutical Schedule and all its sections and appendices. “Section B” of this Pharmaceutical Schedule means the list of Community Pharmaceuticals eligible for Subsidies included in the Schedule. “Section C” of this Pharmaceutical Schedule means the list of community extemporaneously compounded preparations and galenicals eligible for Subsidies included in the Schedule. “Section D” of this Pharmaceutical Schedule means the list of community special foods eligible for Subsidies included in the Schedule. “Section E Part I” of this Pharmaceutical Schedule means the list of Community Pharmaceuticals eligible for Subsidies and available on a Practitioner’s Supply Order included in the Schedule. “Section E Part II” of this Pharmaceutical Schedule means the list of rural areas for the purpose of community Practitioner’s Supply Orders included in the Schedule. “Section F Part I” of this Pharmaceutical Schedule means the part of Section F relating to the exemption from dispensing in Monthly Lots, and requirement to dispense in 90 Day Lots or 180 Day Lots, as applicable, in respect of the Community Pharmaceuticals referred to in this part of Section F; “Section F Part II” of this Pharmaceutical Schedule means the part of Section F relating to the exemption from dispensing in Monthly Lots in respect of the Community Pharmaceuticals referred to in this part of Section F; “Section G” of this Pharmaceutical Schedule means the list of Community Pharmaceuticals eligible for reimbursement of safety caps. “Section H” of this Pharmaceutical Schedule means the general rules for Hospital Pharmaceuticals and the lists of National Contract Pharmaceuticals and any associated DV Pharmaceuticals, of Discretionary Community Supply Pharmaceuticals and Assessed Pharmaceuticals included in Section H of the Schedule.

SECTION A: GENERAL RULES

“Section H Part I” of this Pharmaceutical Schedule means the general rules for Hospital Pharmaceuticals. “Section H Part II” of this Pharmaceutical Schedule means the list of National Contract Pharmaceuticals, the relevant Price, an indication of whether the Pharmaceutical has HSS and any associated DV Pharmaceuticals and DV Limit. “Section H Part III” of this Pharmaceutical Schedule means the list of Discretionary Community Supply Pharmaceuticals. “Special Authority” means that the Community Pharmaceutical or Pharmaceutical Cancer Treatment is only eligible for Subsidy or additional Subsidy for a particular person if an application meeting the criteria speciﬁed in the Schedule has been approved, and the valid Special Authority number is present on the prescription. “Specialist”, in relation to a Prescription, a doctor who holds a current annual practising certiﬁcate and who satisﬁes the criteria set out in paragraphs (a) or (b) or (c) or (d) below: a) i) the doctor is vocationally registered in accordance with the criteria set out by the Medical Council of New Zealand and the HPCA Act 2003 and who has written the Prescription in the course of practising in that area of medicine; and ii) the doctor’s vocational scope of practice is one of those listed below: — anaesthetics, cardiothoracic surgery, dermatology, diagnostic radiology, emergency medicine, general surgery, internal medicine, neurosurgery, obstetrics and gynaecology, occupational medicine, ophthalmology, oral and maxillofacial surgery, otolaryngology head and neck surgery, orthopaedic surgery, paediatric surgery, paediatrics, pathology, plastic and reconstructive surgery, psychological medicine or psychiatry, public health medicine, radiation oncology, rehabilitation medicine, urology and venereology; b) the doctor is recognised by the Ministry of Health as a specialist for the purposes of this Schedule and receives remuneration from a DHB at a level which that DHB considers appropriate for specialists and who has written that Prescription in the course of practising in that area of medicine; c) the doctor is recognised by the Ministry of Health as a specialist in relation to a particular area of medicine for the purpose of writing Prescriptions and who has written the Prescription in the course of practising in that area of medicine; d) the doctor writes the Prescription on DHB stationery and is appropriately authorised by the relevant DHB to do so. “Subsidy” means the maximum amount that the Government will pay Contractors for a Community Pharmaceutical dispensed to a person eligible for Pharmaceutical Beneﬁts and is different from the cost to Government of subsidising that Community Pharmaceutical. For the purposes of a DHB hospital pharmacy claiming for Pharmaceutical Cancer Treatments, Subsidy refers to any payment made to the DHB hospital pharmacy or service provider to which that pharmacy serves, and does not relate to a speciﬁc payment that might be made on submission of a claim. “Supply Order” means a Bulk Supply Order or a Practitioner’s Supply Order. “Unapproved Indication” means, for a Pharmaceutical, an indication for which it is not approved under the Medicines Act 1981. Practitioners prescribing Pharmaceuticals for Unapproved Indications should be aware of, and comply with, their obligations under Section 25 and/or Section 29 of the Medicines Act 1981 and as set out in Section A: General Rules, Part IV (Miscellaneous Provisions) rule 4.6. 1.2 In addition to the above interpretations and deﬁnitions, unless the content requires otherwise, a reference in the Schedule to: a) the singular includes the plural; and b) any legislation includes a modiﬁcation and re-enactment of, legislation enacted in substitution for, and a regulation, Order in Council, and other instrument from time to time issued or made under that legislation, where that legislation, regulation, Order in Council or other instrument has an effect on the prescribing, dispensing or subsidising of Community Pharmaceuticals.

PART II COMMUNITY PHARMACEUTICALS SUBSIDY

2.1 Community Pharmaceuticals eligible for Subsidy include every medicine, therapeutic medical device or related product, or related thing listed in Sections B to G of the Schedule subject to: 2.1.1 clauses 2.2 of the Schedule; and 2.1.2 clauses 3.1 to 4.4 of the Schedule; and 2.1.3 the conditions (if any) speciﬁed in Sections B to G of the Schedule; 2.2 No claim by a Contractor for payment in respect of the supply of Community Pharmaceuticals will be allowed unless

SECTION A: GENERAL RULES

the Community Pharmaceuticals so supplied: 2.2.1 comply with the appropriate standards prescribed by regulations for the time being in force under the Medicines Act 1981; or 2.2.2 in the absence of any such standards, comply with the appropriate standards for the time being prescribed by the British Pharmacopoeia; or 2.2.3 in the absence of the standards prescribed in clauses 2.3.1 and 2.3.2, comply with the appropriate standards for the time being prescribed by the British Pharmaceutical Codex; or 2.2.4 in the absence of the standards prescribed in clauses 2.3.1, 2.3.2 and 2.3.3, are of a grade and quality not lower than those usually applicable to Community Pharmaceuticals intended to be used for medical purposes.

PART III PERIOD AND QUANTITY OF SUPPLY

3.1 Doctors’, Dentists’, Dietitians’, Midwives’, Nurse Prescribers’ and Optometrists’ Prescriptions (other than oral contraceptives) The following provisions apply to all Prescriptions, other than those for an oral contraceptive, written by a Doctor, Dentist, Dietitian, Midwife, Nurse Prescriber or Optometrist unless speciﬁcally excluded: 3.1.1 For a Community Pharmaceutical other than a Class B Controlled Drug, only a quantity suffcient to provide treatment for a period not exceeding three Months will be subsidised. 3.1.2 For methylphenidate hydrochloride and dexamphetamine sulphate (except for Dentist prescriptions), only a quantity sufﬁcient to provide treatment for a period not exceeding one Month will be subsidised. 3.1.3 For a Class B Controlled Drug: a) other than Dentist prescriptions and methylphenidate hydrochloride and dexamphetamine sulphate, only a quantity: i) sufﬁcient to provide treatment for a period not exceeding 10 days; and ii) which has been dispensed pursuant to a Prescription sufﬁcient to provide treatment for a period not exceeding one Month, will be subsidised. b) for a Dentist prescription only such quantity as is necessary to provide treatment for a period not exceeding ﬁve days will be subsidised. 3.1.4 Subject to clauses 3.1.3 and 3.1.7, for a Doctor, Dietitian, Midwife or Nurse Prescriber and 3.1.7 for an Optometrist, where a practitioner has prescribed a quantity of a Community Pharmaceutical sufﬁcient to provide treatment for: a) one Month or less than one Month, but dispensed by the Contractor in quantities smaller than the quantity prescribed, the Community Pharmaceutical will only be subsidised as if that Community Pharmaceutical had been dispensed in a Monthly Lot; b) more than one Month, the Community Pharmaceutical will be subsidised only if it is dispensed: i) in a 90 Day Lot, where the Community Pharmaceutical is a Pharmaceutical covered by Section F Part I of the Pharmaceutical Schedule; or ii) if the Community Pharmaceutical is not a Pharmaceutical referred to in Section F Part I of the Pharmaceutical Schedule, in Monthly Lots, unless: A) the eligible person or his/her nominated representative endorses the back of the Prescription form with a statement identifying which Access Exemption Criterion (Criteria) applies and signs that statement to this effect; or B) both: 1) the Practitioner endorses the Community Pharmaceutical on the Prescription with the words “certiﬁed exemption” written in the Practitioner’s own handwriting, or signed or initialled by the Practitioner; and 2) every Community Pharmaceutical endorsed as “certiﬁed exemption” is covered by Section F Part II of the Pharmaceutical Schedule. 3.1.5 A Community Pharmaceutical is only eligible for Subsidy if the Prescription under which it has been dispensed was presented to the Contractor: a) for a Class B Controlled Drug, within eight days of the date on which the Prescription was written; or b) for any other Community Pharmaceutical, within three Months of the date on which the Prescription was written.

SECTION A: GENERAL RULES

3.1.6 No subsidy will be paid for any Prescription, or part thereof, that is not fulﬁlled within: a) in the case of a Prescription for a total supply of from one to three Months, three Months from the date the Community Pharmaceutical was ﬁrst dispensed; or b) in any other case, one Month from the date the Community Pharmaceutical was ﬁrst dispensed. Only that part of any Prescription that is dispensed within the time frames speciﬁed above is eligible for Subsidy. 3.1.7 If a Community Pharmaceutical: a) is stable for a limited period only, and the Practitioner has endorsed the Prescription with the words “unstable medicine” and has speciﬁed the maximum quantity that may be dispensed at any one time; or b) is stable for a limited period only, and the Contractor has endorsed the Prescription with the words “unstable medicine” and has speciﬁed the maximum quantity that should be dispensed at any one time in all the circumstances of the particular case; or c) is Close Control, The actual quantity dispensed will be subsidised in accordance with any such speciﬁcation. 3.2 Oral Contraceptives The following provisions apply to all Prescriptions written by a Doctor, Midwife or Nurse Prescriber for an oral contraceptive: 3.2.1 The prescribing Doctor, Midwife or Nurse Prescriber must specify on the Prescription the period of treatment for which the Community Pharmaceutical is to be supplied. This period must not exceed six Months. 3.2.2 Where the period of treatment speciﬁed in the Prescription does not exceed six Months, the Community Pharmaceutical is to be dispensed: a) in Lots as speciﬁed in the Prescription if the Community Pharmaceutical is Close Control; or b) where no Lots are speciﬁed, in one Lot sufﬁcient to provide treatment for the period prescribed. 3.2.3 An oral contraceptive is only eligible for Subsidy if the Prescription under which it has been dispensed was presented to the Contractor within three Months of the date on which it was written. 3.2.4 Where a Community Pharmaceutical in a Prescription is Close Control and a repeat on the Prescription remains unfulﬁlled after six Months from the date the Community Pharmaceutical was ﬁrst dispensed only the actual quantity supplied by the Contractor within this time limit will be eligible for Subsidy. 3.3 Original Packs, and Certain Antibiotics 3.3.1 Notwithstanding clauses 3.1 and 3.3 of the Schedule, if a Practitioner prescribes or orders a Community Pharmaceutical that is identiﬁed as an Original Pack (OP) on the Pharmaceutical Schedule and is packed in a container from which it is not practicable to dispense lesser amounts, every reference in those clauses to an amount or quantity eligible for Subsidy, is deemed to be a reference: a) where an amount by weight or volume of the Community Pharmaceutical is speciﬁed in the Prescription, to the smallest container of the Community Pharmaceutical, or the smallest number of containers of the Community Pharmaceutical, sufﬁcient to provide that amount; and b) in every other case, to the amount contained in the smallest container of the Community Pharmaceutical that is manufactured in, or imported into, New Zealand. 3.3.2 If a Community Pharmaceutical is the liquid oral form of an antibiotic to which a diluent must be added by the Contractor at the time of dispensing and it is prescribed or ordered by a Practitioner in an amount that does not coincide with the amount contained in one or more standard packs of that Community Pharmaceutical, Subsidy will be paid for the amount prescribed or ordered by the Practitioner in accordance with either clause 3.1 or clause 3.3 of the Schedule, and for the balance of any pack or packs from which the Community Pharmaceutical has been dispensed. At the time of dispensing the Contractor must keep a record of the quantity discarded. To ensure wastage is reduced, the Contractor should reduce the amount dispensed to make it equal to the quantity contained in a whole pack where: a) the difference the amount dispensed and the amount prescribed by the Practitioner is less than 10% (eg; if a prescription is for 105 mls then a 100ml pack would be dispensed); and b) in the reasonable opinion of the Contractor the difference would not affect the efﬁcacy of the course of treatment prescribed by the Practitioner. Note: For the purposes of audit and compliance it is an act of fraud to claim wastage and then use the wastage amount for any subsequent prescription. 3.4 Dietitians’ Prescriptions The following provisions apply to every Prescription written by a Dietitian:

SECTION A: GENERAL RULES

3.4.1 Prescriptions written by a Dietitian for a Community Pharmaceutical will only be subsidised where they are for either: a) special foods, as listed in Section D; or b) any other Pharmaceutical that has been identiﬁed in Section D of the Pharmaceutical Schedule as being able to be prescribed by a Dietitian, providing that the products being prescribed are not classiﬁed as Prescription Medicines or Restricted Medicines. 3.4.2 For the purposes of Dietitians prescribing pursuant to this clause 3.5, the prescribing and dispensing of these products is required to be in accordance with regulations 41 and 42 of the Medicines Regulations 1984. 3.5 Diabetes Nurse Prescribers’ Prescriptions The following provisions apply to every Prescription written by a Diabetes Nurse Prescriber: 3.5.1 Prescriptions written by a Diabetes Nurse Prescriber for a Community Pharmaceutical will only be subsidised where they are for either: a) a Community Pharmaceutical classiﬁed as a Prescription Medicine or a Restricted Medicine and which a Diabetes Nurse Prescribers is permitted under regulations to prescribe; or b) any other Community Pharmaceutical listed below, being an item that has been identiﬁed as being able to be prescribed by a Diabetes Nurse Prescriber, but which is not classiﬁed as a Prescription Medicine or a Restricted Medicine: aspirin, blood glucose diagnostic test meter, blood glucose diagnostic test strip, glucagon hydrochloride inj 1 mg syringe kit, insulin pen needles, insulin syringes disposable with attached needle, ketone blood beta-ketone electrodes test strip, nicotine, sodium nitroprusside test strip, 3.5.2 Any Diabetes Nurse Prescribers’ prescription for a medication requiring a Special Authority will only be subsidised if it is for a repeat prescription (ie after the initial prescription with Special Authority approval was dispensed). Note: A list of Diabetes Nurse Prescribers will be published periodically in the Update of the Pharmaceutical Schedule for the duration of an initial pilot scheme. After this period there will be no approved DHB demonstration sites and hence no Diabetes Nurse Prescribers.

PART IV MISCELLANEOUS PROVISIONS

4.1 Bulk Supply Orders The following provisions apply to the supply of Community Pharmaceuticals under Bulk Supply Orders: 4.1.1 No Community Pharmaceutical supplied under a Bulk Supply Order will be subsidised unless all the requirements in Section B, C or D of the Schedule applicable to that pharmaceutical are met. 4.1.2 The person who placed the Bulk Supply Order may be called upon by the Ministry of Health to justify the amount ordered. 4.1.3 Class B Controlled Drugs will be subsidised only if supplied under Bulk Supply Orders placed by an institution certiﬁed to provide hospital care under the Health and Disability Services (Safety) Act 2001. 4.1.4 Any order for a Class B Controlled Drug or for buprenorphine hydrochloride must be written on a Special Bulk Supply Order Controlled Drug Form supplied by the Ministry of Health. 4.1.5 Community Pharmaceuticals listed in Part I of the First Schedule to the Medicines Regulations 1984 will be subsidised only if supplied under a Bulk Supply Order placed by an institution certiﬁed to provide hospital care under the Health and Disability Services (Safety) Act 2001 and: a) that institution employs a registered general nurse, registered with the Nursing Council and who holds a current annual practicing certiﬁcate under the HPCA Act 2003; and b) the Bulk Supply Order is supported by a written requisition signed by a Hospital Care Operator. 4.1.6 No Subsidy will be paid for any quantity of a Community Pharmaceutical supplied under a Bulk Supply Order in excess of what is a reasonable monthly allocation for the particular institution, after taking into account stock on hand. 4.1.7 The Ministry of Health may, at any time, by public notiﬁcation, declare that any approved institution within its particular region, is not entitled to obtain supplies of Community Pharmaceuticals under Bulk Supply Orders with effect from the date speciﬁed in that declaration. Any such notice may in like manner be revoked by the Ministry of Health at any time. 4.2 Practitioner’s Supply Orders

SECTION A: GENERAL RULES

The following provisions apply to the supply of Community Pharmaceuticals to Practitioners under a Practitioner’s Supply Order: 4.2.1 Subject to clause 4.2.3, a Practitioner may only order under a Practitioner’s Supply Order those Community Pharmaceuticals listed in Section E Part I and only in such quantities as set out in Section E Part I that the Practitioner requires to ensure medical supplies are available for emergency use, teaching and demonstration purposes, and for provision to certain patient groups where individual prescription is not practicable. 4.2.2 Any order for a Class B Controlled Drug or for buprenorphine hydrochloride must be written on a Special Practitioner’s Supply Order Controlled Drug Form supplied by the Ministry of Health. 4.2.3 A Practitioner may order such Community Pharmaceuticals as he or she expects to be required for personal administration to patients under the Practitioner’s care if: a) the Practitioner’s normal practice is in the speciﬁed areas listed in Section E Part II of the Schedule, or if the Practitioner is a locum for a Practitioner whose normal practice is in such an area. b) the quantities ordered are reasonable for up to one Month’s supply under the conditions normally existing in the practice. (The Practitioner may be called on by the Ministry of Health to justify the amounts of Community Pharmaceuticals ordered.) 4.2.4 No Community Pharmaceutical ordered under a Practitioner’s Supply order will be eligible for Subsidy unless: a) the Practitioner’s Supply Order is made on a form supplied for that purpose by the Ministry of Health, or approved by the Ministry of Health and which: i) is personally signed and dated by the Practitioner; and ii) sets out the Practitioner’s address; and iii) sets out the Community Pharmaceuticals and quantities, and; b) all the requirements of Sections B and C of the Schedule applicable to that pharmaceutical are met. 4.2.5 The Ministry of Health may, at any time, on the recommendation of an Advisory Committee appointed by the Ministry of Health for that purpose, by public notiﬁcation, declare that a Practitioner speciﬁed in such a notice is not entitled to obtain supplies of Community Pharmaceuticals under Practitioner’s Supply Orders until such time as the Ministry of Health notiﬁes otherwise. 4.3 Retail Pharmacy and Hospital Pharmacy-Specialist Restriction The following provisions apply to Prescriptions for Community Pharmaceuticals eligible to be subsidised as “Retail Pharmacy-Specialist” and “Hospital Pharmacy-Specialist”: 4.3.1 Record Keeping It is expected that a record will be kept by both the General Practitioner and the Specialist of the fact of consultation and enough of the clinical details to justify the recommendation. This means referral by telephone will need to be followed up by written consultation. 4.3.2 Expiry The recommendation expires at the end of two years and can be renewed by a further consultation. 4.3.3 The circulation by Specialists of the circumstances under which they are prepared to recommend a particular Community Pharmaceutical is acceptable as a guide. It must however be followed up by the procedure in subclauses 4.3.1 and 4.3.2, for the individual Patient. 4.3.4 The use of preprinted forms and named lists of Specialists (as circulated by some pharmaceutical companies) is regarded as inappropriate. 4.3.5 The Rules for Retail Pharmacy-Specialist and Hospital Pharmacy-Specialist will be audited as part of the Ministry of Health’s routine auditing procedures. 4.4 Pharmaceutical Cancer Treatments 4.4.1 DHBs must provide access to Pharmaceutical Cancer Treatments for the treatment of cancers in their DHB hospitals, and/or in association with Outpatient services provided in their DHB hospitals. 4.4.2 DHBs must only provide access to Pharmaceuticals for the treatment of cancer that are listed as Pharmaceutical Cancer Treatments in Sections A to G of the Schedule, provided that DHBs may provide access to an unlisted pharmaceutical for the treatment of cancer where that unlisted pharmaceutical: a) has Cancer Exceptional Circumstances approval; b) has Community Exceptional Circumstances or Hospital Exceptional Circumstances approval; c) is being used as part of a bona ﬁde clinical trial which has Ethics Committee approval; d) is being used and funded as part of a paediatric oncology service; or e) was being used to treat the patient in question prior to 1 July 2005. 4.4.3 A DHB hospital pharmacy that holds a claiming agreement for Pharmaceutical Cancer Treatements with the

SECTION A: GENERAL RULES

Funder may claim a Subsidy for a Pharmaceutical Cancer Treatment marked as “PCT” or “PCT only” in Sections A to G of this Schedule subject to that Pharmaceutical Cancer Treatment being dispensed in accordance with: a) Part 1; b) clauses 2.1 to 2.3; c) clauses 3.1 to 3.4; and d) clause 4.4, of Section A of the Schedule 4.4.4 A Contractor (other than a DHB hospital pharmacy) may only claim a Subsidy for a Pharmaceutical Cancer Treatment marked as “PCT” in Sections A to G of the Schedule subject to that Pharmaceutical Cancer Treatment being dispensed in accordance with the rules applying to Sections A to G of the Schedule. 4.4.5 Some indications for Pharmaceutical Cancer Treatments listed in the Schedule are Unapproved Indications. Some of these formed part of the October 2001 direction from the Minister of Health as to pharmaceuticals and indications for which DHBs must provide funding. As far as reasonably practicable, these Unapproved Indications are marked in the Schedule. However, PHARMAC makes no representation and gives no guarantee as to the accuracy of this information. Practitioners prescribing Pharmaceutical Cancer Treatments for such Unapproved Indications should: a) be aware of and comply with their obligations under sections 25 and 29 of the Medicines Act 1981, as applicable, and otherwise under the Medicines Act and the Medicines Regulations 1984; b) be aware of and comply with their obligations under the Health and Disability Comissioner’s Code of Consumer Rights, including the requirement to obtain informed consent from the patient (PHARMAC recommends that Practitioners obtain written consent); and c) exercise their own skill, judgement, expertise and discretion, and make their own prescribing decisions with respect to the use of an unapproved Pharmaceutical Cancer Treatment or a Pharmaceutical Cancer Treatment for an Unapproved Indication. 4.5 Practitioners prescribing unapproved Pharmaceuticals Practitioners should, where possible, prescribe Pharmaceuticals that are approved under the Medicines Act 1981. However, the access criteria under which a Pharmaceutical is listed on the Pharmaceutical Schedule may: a) in some case, explicitly permit Government funded access to a Pharmaceutical that is not approved under the Medicines Act 1981 or for an Unapproved Indication; or b) not explicitly preclude Government funded access to a Pharmaceutical when it is used for an Unapproved Indication; Accordingly, if Practitioners are planning on prescribing an unapproved Pharmaceutical or a Pharmaceutical for an Unapproved Indication, Practitioners should: a) be aware of and comply with their obligations under sections 25 and 29 of the Medicines Act 1981, as applicable, and otherwise under that Act and the Medicines Regulations 1984; b) be aware of and comply with their obligations under the Health and Disability Commissioner’s Code of Consumer Rights, including the requirement to obtain informed consent from the patient (PHARMAC recommends that Practitioners obtain written consent); and c) exercise their own skill, judgment, expertise and discretion, and make their own prescribing decisions with respect to the use of an unapproved Pharmaceutical or a Pharmaceutical for an Unapproved Indication. Practitioners should be aware that simply by listing a Pharmaceutical on the Pharmaceutical Schedule PHARMAC makes no representations about whether that Pharmaceutical has any form of approval or consent under, or whether the supply or use of the Pharmaceutical otherwise complies with, the Medicines Act 1981. Further, the Pharmaceutical Schedule does not constitute an advertisement, advertising material or a medical advertisement as deﬁned in the Medicines Act or otherwise. 4.6 Substitution Where a Practitioner has prescribed a brand of a Community Pharmaceutical that has no Subsidy or has a Manufacturer’s Price that is greater than the Subsidy and there is an alternative fully subsidised Community Pharmaceutical available, a Contractor may dispense the fully subsidised Community Pharmaceutical, unless either or both of the following circumstances apply: a) there is a clinical reason why substitution should not occur; or b) the prescriber has marked the prescription with a statement such as ‘no brand substitution premitted’ Such an Authority to Substitute is valid whether or not there is a ﬁnancial implication for the Pharmaceutical Budget.

SECTION A: GENERAL RULES

When dispensing a subsidised alternative brand, the Contractor must annotate and sign the prescription and inform the patient of the brand change. 4.7 Alteration to Presentation of Pharmaceutical Dispensed A Contractor, when dispensing a subsidised Community Pharmaceutical, may alter the presentation of a Pharmaceutical dispensed to another subsidised presentation but may not alter the dose, frequency and/or total daily dose. This may only occur when it is not practicable for the contractor to dispense the requested presentation. If the change will result in additional cost to the DHBs, then annotation of the prescription by the dispensing pharmacist must occur stating the reason for the change, and the Contractor must initial the change for the purposes of Audit. 4.8 Conﬂict in Provisions If any rules in Sections B-G of this Schedule conﬂict with the rules in Section A, the rules in Sections B-G apply.

SECTION B: ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Antacids and Antiﬂatulants Antacids and Reﬂux Barrier Agents

ALGINIC ACID Sodium alginate 225 mg and magnesium alginate 87.5 mg per sachet .................................................................................... 4.50

Gaviscon Infant

CALCIUM CARBONATE WITH AMINOACETIC ACID F Tab 420 mg with aminoacetic acid 180 mg – Higher subsidy of $6.30 per 100 tab with Endorsement........................................ 3.00 100 (6.30) Titralac Additional subsidy by endorsement is available for pregnant women. The prescription must be endorsed accordingly. SIMETHICONE F Oral liq aluminium hydroxide 200 mg with magnesium hydroxide 200 mg and activated simethicone 20 mg per 5 ml ............... 1.50 500 ml (4.26) Mylanta P SODIUM ALGINATE F Tab 500 mg with sodium bicarbonate 267 mg and calcium carbonate 160 mg - peppermint ﬂavour ....................................... 1.80 (8.60) F Oral liq 500 mg with sodium bicarbonate 267 mg and calcium carbonate 160 mg per 10 ml ........................................................ 1.50 (4.95)

60 Gaviscon Double Strength 500 ml Acidex

Phosphate Binding Agents

ALUMINIUM HYDROXIDE Tab 600 mg .......................................................................................12.56 100

Alu-Tab

Antidiarrhoeals Agents Which Reduce Motility

DIPHENOXYLATE HYDROCHLORIDE WITH ATROPINE SULPHATE F Tab 2.5 mg with atropine sulphate 25 µg ............................................3.90 LOPERAMIDE HYDROCHLORIDE – Up to 30 cap available on a PSO F Tab 2 mg .............................................................................................8.95 F Cap 2 mg ............................................................................................8.95 100 400 400

Diastop Nodia Diamide Relief

Rectal and Colonic Anti-inﬂammatories

BUDESONIDE Cap 3 mg – Special Authority see SA1155 on the next page – Retail pharmacy ................................................................... 166.50

Entocort CIR

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA1155 Special Authority for Subsidy Initial application — (Crohn’s disease) from any relevant practitioner. Approvals valid for 6 months for applications meeting the following criteria: Both: 1 Mild to moderate ileal, ileocaecal or proximal Crohn’s disease; and 2 Any of the following: 2.1 Diabetes; or 2.2 Cushingoid habitus; or 2.3 Osteoporosis where there is signiﬁcant risk of fracture; or 2.4 Severe acne following treatment with conventional corticosteroid therapy; or 2.5 History of severe psychiatric problems associated with corticosteroid treatment; or 2.6 History of major mental illness (such as bipolar affective disorder) where the risk of conventional corticosteroid treatment causing relapse is considered to be high; or 2.7 Relapse during pregnancy (where conventional corticosteroids are considered to be contraindicated). Initial application — (collagenous and lymphocytic colitis (microscopic colitis)) from any relevant practitioner. Approvals valid for 6 months where patient has a diagnosis of microscopic colitis (collagenous or lymphocytic colitis) by colonoscopy with biopsies. Initial application — (gut Graft versus Host disease) from any relevant practitioner. Approvals valid for 6 months where patient has a gut Graft versus Host disease following allogenic bone marrow transplantation*. Note: Indication marked with * is an Unapproved Indication. Renewal from any relevant practitioner. Approvals valid for 6 months where the treatment remains appropriate and the patient is beneﬁting from treatment. Note: Clinical trials for Entocort CIR use beyond three months demonstrated no improvement in relapse rate. HYDROCORTISONE ACETATE Rectal foam 10%, CFC-Free (14 applications) .................................23.00 21.1 g OP Colifoam MESALAZINE Tab 400 mg .......................................................................................49.50 Tab EC 500 mg .................................................................................49.50 Tab long-acting 500 mg ....................................................................59.05 Enema 1 g per 100 ml ......................................................................45.96 Suppos 500 mg ................................................................................22.80 Suppos 1 g .......................................................................................50.96 OLSALAZINE Tab 500 mg .......................................................................................59.86 Cap 250 mg ......................................................................................31.51 SODIUM CROMOGLYCATE Cap 100 mg ......................................................................................89.21 SULPHASALAZINE F Tab 500 mg – For sulphasalazine oral liquid formulation refer, page 172 .................................................................................... 11.68 F Tab EC 500 mg .................................................................................12.89 100 100 100 7 20 28 100 100 100

Asacol Asamax Pentasa Pentasa Asacol Pentasa Dipentum Dipentum Nalcrom

100 100

Salazopyrin Salazopyrin EN

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Antihaemorrhoidals Corticosteroids

FLUOCORTOLONE CAPROATE WITH FLUOCORTOLONE PIVALATE AND CINCHOCAINE Oint 950 µg, with ﬂuocortolone pivalate 920 µg, and cinchocaine hydrochloride 5 mg per g ............................................. 6.35 30 g OP Suppos 630 µg, with ﬂuocortolone pivalate 610 µg, and cinchocaine hydrochloride 1 mg ....................................................... 2.66 12 HYDROCORTISONE WITH CINCHOCAINE Oint 5 mg with cinchocaine hydrochloride 5 mg per g ......................15.00 Suppos 5 mg with cinchocaine hydrochloride 5 mg per g ..................9.90 30 g OP 12

Ultraproct Ultraproct Proctosedyl Proctosedyl

Antispasmodics and Other Agents Altering Gut Motility

ATROPINE SULPHATE F Inj 600 µg, 1 ml – Up to 5 inj available on a PSO .............................52.00 HYOSCINE N-BUTYLBROMIDE F Tab 10 mg ...........................................................................................1.48 F Inj 20 mg, 1 ml – Up to 5 inj available on a PSO ................................9.57 MEBEVERINE HYDROCHLORIDE F Tab 135 mg .......................................................................................18.00 50 20 5 90

AstraZeneca Gastrosoothe Buscopan Colofac

Antiulcerants Antisecretory and Cytoprotective

MISOPROSTOL F Tab 200 µg ........................................................................................52.70 120

Cytotec

Helicobacter Pylori Eradication

CLARITHROMYCIN Tab 500 mg – Subsidy by endorsement ............................................10.95 14 Apo-Clarithromycin 23.30 Klamycin a) Maximum of 14 tab per prescription b) Subsidised only if prescribed for helicobacter pylori eradication and prescription is endorsed accordingly. Note: the prescription is considered endorsed if clarithromycin is prescribed in conjunction with a proton pump inhibitor and either amoxycillin or metronidazole.

H2 Antagonists

CIMETIDINE – Only on a prescription F Tab 200 mg .........................................................................................5.00 (7.50) F Tab 400 mg .......................................................................................10.00 (12.00) FAMOTIDINE – Only on a prescription F Tab 20 mg ...........................................................................................8.10 F Tab 40 mg .........................................................................................11.35 100 Apo-Cimetidine 100 Apo-Cimetidine 250 250

Famox Famox

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

RANITIDINE HYDROCHLORIDE – Only on a prescription F Tab 150 mg .........................................................................................6.79 F Tab 300 mg .........................................................................................9.34 F Oral liq 150 mg per 10 ml ...................................................................5.92 F Inj 25 mg per ml, 2 ml .........................................................................8.75

250 250 300 ml 5

Arrow-Ranitidine Arrow-Ranitidine Peptisoothe Zantac

Proton Pump Inhibitors

LANSOPRAZOLE F Cap 15 mg ..........................................................................................3.27 3.50 F Cap 30 mg ..........................................................................................4.34 4.65 OMEPRAZOLE For omeprazole suspension refer, page 175 F Cap 10 mg .........................................................................................0.97 2.91 F Cap 20 mg .........................................................................................1.26 3.78 F Cap 40 mg .........................................................................................1.86 5.57 F Powder – Only in combination .........................................................42.50 Only in extemporaneously compounded omeprazole suspension. F Inj 40 mg ...........................................................................................28.65 (Dr Reddy’s Omeprazole Cap 10 mg to be delisted 1 January 2012) (Dr Reddy’s Omeprazole Cap 20 mg to be delisted 1 January 2012) (Dr Reddy’s Omeprazole Cap 40 mg to be delisted 1 January 2012) PANTOPRAZOLE F Tab 20 mg ...........................................................................................1.23 F Tab 40 mg ...........................................................................................1.54 F Inj 40 mg .............................................................................................6.50 28 28 1 28 28

Lanzol Relief Solox Lanzol Relief Solox

30 90 30 90 30 90 5g 5

Dr Reddy’s

Omeprazole

Omezol Relief Dr Reddy’s

Omeprazole

Omezol Relief Dr Reddy’s

Omeprazole

Omezol Relief Midwest Dr Reddy’s

Omeprazole

Dr Reddy’s

Pantoprazole

Dr Reddy’s

Pantoprazole

Pantocid IV

Site Protective Agents

SUCRALFATE Tab 1 g ..............................................................................................35.50 (48.28) 120 Carafate

Diabetes Hyperglycaemic Agents

GLUCAGON HYDROCHLORIDE Inj 1 mg syringe kit – Up to 5 kit available on a PSO........................27.00 1

Glucagen Hypokit

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Insulin - Short-acting Preparations

INSULIN NEUTRAL L Inj human 100 u per ml .....................................................................25.26 L Inj human 100 u per ml, 3 ml ............................................................42.66 10 ml OP 5

Actrapid Humulin R Actrapid Penﬁll Humulin R

Insulin - Intermediate-acting Preparations

INSULIN ISOPHANE L Inj human 100 u per ml .....................................................................17.68 L Inj human 100 u per ml, 3 ml ............................................................29.86 INSULIN ISOPHANE WITH INSULIN NEUTRAL L Inj human with neutral insulin 100 u per ml ......................................25.26 L Inj human with neutral insulin 100 u per ml, 3 ml .............................42.66 10 ml OP 5

Humulin NPH Protaphane Humulin NPH Protaphane Penﬁll Humulin 30/70 Mixtard 30 Humulin 30/70 PenMix 30 PenMix 40 PenMix 50

10 ml OP 5

INSULIN LISPRO WITH INSULIN LISPRO PROTAMINE L Inj lispro 25% with insulin lispro protamine 75% 100 u per ml, 3 ml ............................................................................................52.15 L Inj lispro 50% with insulin lispro protamine 50% 100 u per ml,3 ml ...............................................................................................52.15

5 5

Humalog Mix 25 Humalog Mix 50

Insulin - Long-acting Preparations

INSULIN GLARGINE Note: Only for patients meeting one of the following criteria: a) Type 1 diabetes; or b) Other condition related diabetes (e.g. Cystic Fibrosis, diabetes in pregnancy, pancreatectomy patients); or c) Type 2 diabetes after there has been unacceptable hypoglycaemic events with a 3 month trial of an insulin regimen; or d) Type 2 diabetes who require insulin therapy and who require assistance from a carer or healthcare professional to administer their insulin injections. L Inj 100 u per ml, 10 ml ......................................................................63.00 1 Lantus L Inj 100 u per ml, 3 ml ........................................................................94.50 5 Lantus L Inj 100 u per ml, 3 ml disposable pen ...............................................94.50 5 Lantus SoloStar

Insulin - Rapid Acting Preparations

INSULIN ASPART L Inj 100 u per ml, 3 ml ........................................................................51.19 L Inj 100 u per ml, 10 ml ......................................................................30.03 INSULIN GLULISINE L Inj 100 u per ml, 10 ml ......................................................................27.03 L Inj 100 u per ml, 3 ml ........................................................................46.07 L Inj 100 u per ml, 3 ml disposable pen ...............................................46.07 5 1 1 5 5

NovoRapid Penﬁll NovoRapid Apidra Apidra Apidra SoloStar

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

INSULIN LISPRO L Inj 100 u per ml, 10 ml ......................................................................34.92 L Inj 100 u per ml, 3 ml ........................................................................59.52

10 ml OP 5

Humalog Humalog

Alpha Glucosidase Inhibitors

ACARBOSE F Tab 50 mg .........................................................................................16.50 F Tab 100 mg .......................................................................................26.70 90 90

Glucobay Glucobay

Oral Hypoglycaemic Agents

GLIBENCLAMIDE F Tab 5 mg .............................................................................................5.00 GLICLAZIDE F Tab 80 mg .........................................................................................17.60 GLIPIZIDE F Tab 5 mg .............................................................................................3.50 METFORMIN HYDROCHLORIDE F Tab immediate-release 500 mg ..........................................................8.09 F Tab immediate-release 850 mg ..........................................................6.67 PIOGLITAZONE – Special Authority see SA0959 below – Retail pharmacy Tab 15 mg ...........................................................................................2.61 Tab 30 mg ...........................................................................................5.23 Tab 45 mg ...........................................................................................7.80 100 500 100 500 250 28 28 28

Daonil Apo-Gliclazide Minidiab Apotex Apotex Pizaccord Pizaccord Pizaccord

¾SA0959 Special Authority for Subsidy Initial application — (Patients with type 2 diabetes) from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Either: 1 Patient has not achieved glycaemic control on maximum doses of metformin or a sulphonylurea or where either or both are contraindicated or not tolerated; or 2 Patient is on insulin.

Diabetes Management Ketone Testing

KETONE BLOOD BETA-KETONE ELECTRODES – Maximum of 20 strip per prescription Test strip – Not on a BSO...................................................................7.07 10 strip OP SODIUM NITROPRUSSIDE – Maximum of 50 strip per prescription F Test strip – Not on a BSO.................................................................14.14

Optium Blood

Ketone Test Strips

50 strip OP

Ketostix

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Blood Glucose Testing

BLOOD GLUCOSE DIAGNOSTIC TEST METER – Subsidy by endorsement a) Maximum of 1 meter per prescription b) 1) A diagnostic blood glucose test meter is subsidised for patients who begin insulin or sulphonylurea therapy after 1 March 2005 or is prescribed for a pregnant woman with diabetes. 2) Only one meter per patient. No further prescriptions will be subsidised. The prescription must be endorsed accordingly. Meter ..................................................................................................6.00 1 CareSens POP 9.00 CareSens II FreeStyle Lite On Call Advanced Optium Xceed 19.00 Accu-Chek Performa BLOOD GLUCOSE DIAGNOSTIC TEST STRIP The number of test strips available on a prescription is restricted to 50 unless: 1) Prescribed with insulin or a sulphonylurea but are on a different prescription and the prescription is endorsed accordingly; or 2) Prescribed on the same prescription as insulin or a sulphonylurea in which case the prescription is deemed to be endorsed; or 3) Prescribed for a pregnant woman with diabetes and endorsed accordingly. SensoCard blood glucose test strips are subsidised only if prescribed for a patient who is severely visually impaired and is using a SensoCard Plus Talking Blood Glucose Monitor. Blood glucose test strips ..................................................................21.65 50 test OP Accu-Chek Performa FreeStyle Lite Optium 5 second test 26.20 SensoCard Blood glucose test strips × 50 and lancets × 5 ...............................19.10 50 test OP On Call Advanced 19.60 CareSens

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Insulin Syringes and Needles

Subsidy is available for disposable insulin syringes, needles, and pen needles if prescribed on the same form as the one used for the supply of insulin or when prescribed for an insulin patient and the prescription is endorsed accordingly. INSULIN PEN NEEDLES – Maximum of 100 dev per prescription F 29 g × 12.7 mm ..................................................................................3.15 30 B-D Micro-Fine 10.50 100 B-D Micro-Fine ABM 11.75 SC Proﬁ-Fine F 31 g × 5 mm .....................................................................................11.75 100 B-D Micro-Fine SC Proﬁ-Fine F 31 g × 6 mm .....................................................................................10.50 100 ABM 11.75 Fine Ject 10.50 (26.00) NovoFine F 31 g × 8 mm .......................................................................................3.15 30 B-D Micro-Fine 10.50 100 B-D Micro-Fine ABM 11.75 SC Proﬁ-Fine F 32 g × 4 mm .....................................................................................10.50 100 B-D Micro-Fine INSULIN SYRINGES, DISPOSABLE WITH ATTACHED NEEDLE – Maximum of 100 dev per prescription F Syringe 0.3 ml with 29 g × 12.7 mm needle ....................................13.00 100 ABM 1.30 10 (1.99) B-D Ultra Fine 13.00 100 B-D Ultra Fine DM Ject F Syringe 0.3 ml with 31 g × 8 mm needle .........................................13.00 100 ABM 1.30 10 (1.99) B-D Ultra Fine II 13.00 100 B-D Ultra Fine II DM Ject F Syringe 0.5 ml with 29 g × 12.7 mm needle ....................................13.00 100 ABM 1.30 10 (1.99) B-D Ultra Fine 13.00 100 B-D Ultra Fine DM Ject F Syringe 0.5 ml with 31 g × 8 mm needle .........................................13.00 100 ABM 1.30 10 (1.99) B-D Ultra Fine II 13.00 100 B-D Ultra Fine II DM Ject F Syringe 1 ml with 29 g × 12.7 mm needle .......................................13.00 100 ABM DM Ject 1.30 10 (1.99) B-D Ultra Fine 13.00 100 B-D Ultra Fine F Syringe 1 ml with 31 g × 8 mm needle ............................................13.00 100 ABM 1.30 10 (1.99) B-D Ultra Fine II 13.00 100 B-D Ultra Fine II DM Ject

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Digestives Including Enzymes

PANCREATIC ENZYME Cap EC 10,000 BP u lipase, 9,000 BP u amylase and 210 BP u protease .....................................................................34.93 Cap EC 25,000 BP u lipase, 18,000 BP u amylase, 1,000 BP u protease ..................................................................94.38 Cap EC 25,000 BP u lipase, 22,500 BP u amylase, 1,250 BP u protease ..................................................................94.40

100 100 100

Creon 10000 Creon Forte Panzytrat

URSODEOXYCHOLIC ACID – Special Authority see SA1003 below – Retail pharmacy Cap 300 mg – For ursodeoxycholic acid oral liquid formulation refer, page 172................................................................... 179.00 100

Actigall

¾SA1003 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 6 months for applications meeting the following criteria: Either: 1 Patient diagnosed with cholestasis of pregnancy; or 2 Both: 2.1 Primary biliary cirrhosis conﬁrmed by antimitochondrial antibody titre (AMA) > 1:80, and raised cholestatic liver enzymes with or without raised serum IgM or, if AMA is negative, by liver biopsy; and 2.2 Patient not requiring a liver transplant (bilirubin > 170umol/l; decompensated cirrhosis). Note: Liver biopsy is not usually required for diagnosis but is helpful to stage the disease. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment. Note: Ursodeoxycholic acid is not an appropriate therapy for patients requiring a liver transplant (bilirubin > 170 micromol/l; decompensated cirrhosis). These patients should be referred to an appropriate transplant centre. Treatment failure – doubling of serum bilirubin levels, absence of a signiﬁcant decrease in ALP or ALT and AST, development of varices, ascites or encephalopathy, marked worsening of pruritus or fatigue, histological progression by two stages, or to cirrhosis, need for transplantation.

Laxatives Bulk-forming Agents

MUCILAGINOUS LAXATIVES – Only on a prescription F Dry ......................................................................................................6.02 F Sugar Free ..........................................................................................3.31 (10.60) MUCILAGINOUS LAXATIVES WITH STIMULANTS F Dry ......................................................................................................2.41 (8.72) 6.02 (17.32) 500 g OP 275 g OP

Konsyl-D

Mucilax

200 g OP Normacol Plus 500 g OP Normacol Plus

Faecal Softeners

DOCUSATE SODIUM – Only on a prescription F Cap 50 mg ..........................................................................................2.57 F Cap 120 mg ........................................................................................3.48 F Enema conc 18% ...............................................................................5.40 DOCUSATE SODIUM WITH SENNOSIDES F Tab 50 mg with total sennosides 8 mg ...............................................6.38 100 100 100 ml OP 200

Laxofast 50 Laxofast 120 Coloxyl Laxsol

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

POLOXAMER – Only on a prescription Not funded for use in the ear. F Oral drops 10% ...................................................................................3.78

30 ml OP

Coloxyl

Osmotic Laxatives

GLYCEROL F Suppos 3.6 g – Only on a prescription ...............................................6.00 LACTULOSE – Only on a prescription F Oral liq 10 g per 15 ml ........................................................................7.68 MACROGOL 3350 – Special Authority see SA0891 below – Retail pharmacy Powder 13.125 g, sachets – Maximum of 60 sach per prescription ...................................................................................... 18.14 20 1,000 ml

PSM Laevolac

Movicol

¾SA0891 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 6 months where the patient has problematic constipation requiring intervention with a per rectal preparation despite an adequate trial of other oral pharmacotherapies including lactulose where lactulose is not contraindicated. Renewal from any relevant practitioner. Approvals valid for 12 months where the patient is compliant and is continuing to gain beneﬁt from treatment. SODIUM ACID PHOSPHATE – Only on a prescription Enema 16% with sodium phosphate 8% ............................................2.50 1 Fleet Phosphate Enema SODIUM CITRATE WITH SODIUM LAURYL SULPHOACETATE – Only on a prescription Enema 90 mg with sodium lauryl sulphoacetate 9 mg per ml, 5 ml ............................................................................................ 25.00 50

Micolette

Stimulant Laxatives

BISACODYL – Only on a prescription F Tab 5 mg .............................................................................................4.99 F Suppos 5 mg ......................................................................................3.00 F Suppos 10 mg ....................................................................................3.00 DANTHRON WITH POLOXAMER – Only on a prescription Note: Only for the prevention or treatment of constipation in the terminally ill. Oral liq 25 mg with poloxamer 200 mg per 5 ml .................................9.50 Oral liq 75 mg with poloxamer 1 g per 5 ml ......................................13.95 SENNA – Only on a prescription F Tab, standardised ...............................................................................0.43 (1.72) 2.17 (6.16) 200 6 6

Lax-Tab Dulcolax Dulcolax

300 ml 300 ml 20

Pinorax Pinorax Forte

Senokot 100 Senokot

Metabolic Disorder Agents Gaucher’s Disease

IMIGLUCERASE – Special Authority see SA0473 on the next page – Retail pharmacy Inj 40 iu per ml, 200 iu vial ...........................................................1,072.00 1 Inj 40 iu per ml, 400 iu vial ...........................................................2,144.00 1

Cerezyme Cerezyme

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA0473 Special Authority for Subsidy Special Authority approved by the Gaucher’s Treatment Panel Notes: Subject to a budgetary cap. Applications will be considered and approved subject to funding availability. Application details may be obtained from PHARMAC’s website http://www.pharmac.govt.nz or: The Co-ordinator, Gaucher’s Treatment Panel Phone: (04) 460 4990 PHARMAC, PO Box 10 254 Facsimile: (04) 916 7571 Wellington Email: gaucherpanel@pharmac.govt.nz

Mouth and Throat Agents Used in Mouth Ulceration

BENZYDAMINE HYDROCHLORIDE Soln 0.15% .........................................................................................3.60 (7.14) 9.00 (15.36) CHLORHEXIDINE GLUCONATE Mouthwash 0.2% ................................................................................3.87 CHOLINE SALICYLATE WITH CETALKONIUM CHLORIDE F Adhesive gel 8.7% with cetalkonium chloride 0.01% .........................2.06 (5.62) SODIUM CARBOXYMETHYLCELLULOSE With pectin and gelatin paste ...........................................................17.20 1.52 (3.60) 4.55 (7.90) With pectin and gelatin powder ..........................................................8.48 (10.95) TRIAMCINOLONE ACETONIDE 0.1% in Dental Paste USP ..................................................................4.34 200 ml Difﬂam 500 ml Difﬂam 200 ml OP 15 g OP Bonjela 56 g OP 5 g OP 15 g OP Orabase 28 g OP Stomahesive 5 g OP

Rivacol

Stomahesive

Orabase

Oracort

Oropharyngeal Anti-infectives

AMPHOTERICIN B Lozenges 10 mg .................................................................................5.86 MICONAZOLE Oral gel 20 mg per g ...........................................................................8.70 NYSTATIN Oral liq 100,000 u per ml ....................................................................3.19 20 40 g OP 24 ml OP

Fungilin Daktarin Nilstat

Other Oral Agents

For folinic mouthwash, pilocarpine oral liquid or saliva substitute formula refer, page 175 HYDROGEN PEROXIDE F Soln 10 vol – Maximum of 200 ml per prescription.............................1.28 100 ml THYMOL GLYCERIN F Compound, BPC .................................................................................9.15 500 ml

PSM PSM

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Vitamins

Alpha tocopheryl acetate is available fully subsidised for speciﬁc patients at the Medical Director of PHARMAC’s discretion. Refer to PHARMAC website www.pharmac.govt.nz for the “Alpha tocopheryl acetate information sheet and application form”.

Vitamin A

VITAMIN A WITH VITAMINS D AND C Soln 1000 u with Vitamin D 400 u and ascorbic acid 30 mg per 10 drops ................................................................................4.50

10 ml OP

Vitadol C

Vitamin B

HYDROXOCOBALAMIN F Inj 1 mg per ml, 1 ml – Up to 6 inj available on a PSO .......................6.15 PYRIDOXINE HYDROCHLORIDE a) No more than 100 mg per dose b) Only on a prescription F Tab 25 mg – No patient co-payment payable .....................................2.20 F Tab 50 mg .........................................................................................12.16 THIAMINE HYDROCHLORIDE – Only on a prescription F Tab 50 mg ...........................................................................................5.62 VITAMIN B COMPLEX F Tab, strong, BPC ................................................................................4.70 3

ABM

Hydroxocobalamin

90 500 100 500

PyridoxADE Apo-Pyridoxine Apo-Thiamine B-PlexADE

Vitamin C

ASCORBIC ACID a) No more than 100 mg per dose b) Only on a prescription F Tab 100 mg .......................................................................................13.80

500

Vitala-C

Vitamin D

ALFACALCIDOL Cap 0.25 µg ......................................................................................26.32 Cap 1 µg ...........................................................................................87.98 Oral drops 2 µg per ml ......................................................................60.68 CALCITRIOL F Cap 0.25 µg ........................................................................................3.03 F Cap 0.5 µg ..........................................................................................5.62 F Oral liq 1 µg per ml ...........................................................................39.40 CHOLECALCIFEROL F Tab 1.25 mg (50,000 iu) – Maximum of 12 tab per prescription .........7.76 100 100 20 ml OP 30 30 10 ml OP 12

One-Alpha One-Alpha One-Alpha Airﬂow Airﬂow Rocaltrol solution Cal-d-Forte

Multivitamin Preparations

MULTIVITAMINS – Special Authority see SA1036 on the next page – Retail pharmacy Powder ..............................................................................................72.00 200 g OP

Paediatric Seravit

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA1036 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid without further renewal unless notiﬁed where the patient has inborn errors of metabolism. Renewal from any relevant practitioner. Approvals valid without further renewal unless notiﬁed where patient has had a previous approval for multivitamins. VITAMINS F Tab (BPC cap strength) ......................................................................8.00 1,000 MultiADE F Cap (fat soluble vitamins A, D, E, K) – Special Authority see SA1002 below – Retail pharmacy .............................................23.40 60 Vitabdeck ¾SA1002 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Either: 1 Patient has cystic ﬁbrosis with pancreatic insufﬁciency; or 2 Patient is an infant or child with liver disease or short gut syndrome.

Minerals Calcium

CALCIUM CARBONATE F Tab eff 1.75 g (1 g elemental) .............................................................6.21 F Tab 1.25 g (500 mg elemental) ...........................................................6.38 F Tab 1.5 g (600 mg elemental) .............................................................7.66 CALCIUM GLUCONATE F Inj 10%, 10 ml ...................................................................................21.40 30 250 250 10

Calsource Arrow-Calcium Calci-Tab 500 Calci-Tab 600 Mayne

Fluoride

SODIUM FLUORIDE Tab 1.1 mg (0.5 mg elemental) ...........................................................5.00 100

PSM

Iodine

POTASSIUM IODATE Tab 256 µg (150 µg elemental iodine) ................................................7.55 90

NeuroKare

Iron

FERROUS FUMARATE Tab 200 mg (65 mg elemental) ...........................................................4.35 FERROUS FUMARATE WITH FOLIC ACID Tab 310 mg (100 mg elemental) with folic acid 350 µg ......................4.75 FERROUS SULPHATE F Tab long-acting 325 mg (105 mg elemental) ......................................1.01 (4.26) 5.06 (15.58) F‡ Oral liq 30 mg per 1 ml (6 mg elemental per 1 ml) ...........................10.30 100 60 30 Ferrograd 150 Ferrograd 500 ml

Ferro-tab Ferro-F-Tabs

Ferodan

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ALIMENTARY TRACT AND METABOLISM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

FERROUS SULPHATE WITH FOLIC ACID F Tab long-acting 325 mg (105 mg elemental) with folic acid 350 µg .........................................................................................1.80 (3.73) IRON POLYMALTOSE Inj 50 mg per ml, 2 ml .......................................................................19.90

30 Ferrograd-Folic 5

Ferrum H

Magnesium

For magnesium hydroxide mixture refer, page 175 MAGNESIUM SULPHATE Inj 49.3%, 5 ml ..................................................................................26.60

Mayne

Zinc

ZINC SULPHATE F Cap 137.4 mg (50 mg elemental) .....................................................11.00 100

Zincaps

Agents Used in the Treatment of Poisonings

CHARCOAL F Tab 300 mg .........................................................................................7.13 (9.77) F Oral liq 50 g per 250 ml ....................................................................43.50 a) Up to 250 ml available on a PSO b) Only on a PSO SODIUM CALCIUM EDETATE F Inj 200 mg per ml, 5 ml .....................................................................53.31 (156.71) 100 Red Seal 250 ml OP

Carbosorb-X

6 Calcium Disodium Versenate

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

BLOOD AND BLOOD FORMING ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Antianaemics Hypoplastic and Haemolytic

¾SA0922 Special Authority for Subsidy Initial application only from a relevant specialist. Approvals valid for 2 years for applications meeting the following criteria: Both: 1 Both: 1.1 patient in chronic renal failure; and 1.2 Haemoglobin ≤ 100g/L; and 2 Any of the following: 2.1 Both: 2.1.1 patient is not diabetic; and 2.1.2 glomerular ﬁltration rate ≤ 30ml/min; or 2.2 Both: 2.2.1 patient is diabetic; and 2.2.2 glomerular ﬁltration rate ≤ 45ml/min; or 2.3 patient is on haemodialysis or peritoneal dialysis. Renewal only from a relevant specialist. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment. Notes: Erythropoietin beta is indicated in the treatment of anaemia associated with chronic renal failure (CRF) where no cause for anaemia other than CRF is detected and there is adequate monitoring of iron stores and iron replacement therapy. The Cockroft-Gault Formula may be used to estimate glomerular ﬁltration rate (GFR) in persons 18 years and over: GFR (ml/min) (male) = (140 - age) × Ideal Body Weight (kg) / 814 × serum creatinine (mmol/l) GFR (ml/min) (female) = Estimated GFR (male) × 0.85 ERYTHROPOIETIN ALPHA – Special Authority see SA0922 above – Retail pharmacy Inj human recombinant 1,000 iu preﬁlled syringe .............................48.68 6 Eprex Inj human recombinant 2,000 iu, preﬁlled syringe ..........................120.18 6 Eprex Inj human recombinant 3,000 iu, preﬁlled syringe ..........................166.87 6 Eprex Inj human recombinant 4,000 iu, preﬁlled syringe ..........................193.13 6 Eprex Inj human recombinant 5,000 iu, preﬁlled syringe ..........................243.26 6 Eprex Inj human recombinant 6,000 iu, preﬁlled syringe ..........................291.92 6 Eprex Inj human recombinant 10,000 iu, preﬁlled syringe ........................395.18 6 Eprex ERYTHROPOIETIN BETA – Special Authority see SA0922 above – Retail pharmacy Inj 2,000 iu, preﬁlled syringe ...........................................................120.18 Inj 3,000 iu, preﬁlled syringe ...........................................................166.87 Inj 4,000 iu, preﬁlled syringe ...........................................................193.13 Inj 5,000 iu, preﬁlled syringe ...........................................................243.26 Inj 6,000 iu, preﬁlled syringe ...........................................................291.29 Inj 10,000 iu, preﬁlled syringe .........................................................395.18 6 6 6 6 6 6

NeoRecormon NeoRecormon NeoRecormon NeoRecormon NeoRecormon NeoRecormon

Megaloblastic

FOLIC ACID F Tab 0.8 mg ........................................................................................19.80 F Tab 5 mg ...........................................................................................10.21 Oral liq 50 µg per ml .........................................................................21.05 1,000 500 25 ml OP

Apo-Folic Acid Apo-Folic Acid Biomed

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

BLOOD AND BLOOD FORMING ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Antiﬁbrinolytics, Haemostatics and Local Sclerosants

SODIUM TETRADECYL SULPHATE F Inj 0.5% 2 ml .....................................................................................23.20 (45.52) F Inj 1% 2 ml ........................................................................................25.00 (48.98) F Inj 3% 2 ml ........................................................................................28.50 (55.91) TRANEXAMIC ACID Tab 500 mg .......................................................................................32.92 5 Fibro-vein 5 Fibro-vein 5 Fibro-vein 100

Cyklokapron

Vitamin K

PHYTOMENADIONE Inj 2 mg per 0.2 ml – Up to 5 inj available on a PSO..........................8.00 Inj 10 mg per ml, 1 ml – Up to 5 inj available on a PSO .....................9.21 5 5

Konakion MM Konakion MM

Antithrombotic Agents Antiplatelet Agents

ASPIRIN F Tab 100 mg .......................................................................................14.00 CLOPIDOGREL Tab 75 mg – For clopidogrel oral liquid formulation refer, page 172 ............................................................................................. 16.25 DIPYRIDAMOLE F Tab 25 mg – For dipyridamole oral liquid formulation refer, page 172 ......................................................................................8.36 F Tab long-acting 150 mg ....................................................................11.52 990

Ethics Aspirin EC

Apo-Clopidogrel

84 60

Persantin Pytazen SR

Heparin and Antagonist Preparations

ENOXAPARIN SODIUM – Special Authority see SA1174 below – Retail pharmacy Inj 20 mg ...........................................................................................39.20 Inj 40 mg ...........................................................................................52.30 Inj 60 mg ...........................................................................................78.85 Inj 80 mg .........................................................................................105.12 Inj 100 mg .......................................................................................135.20 Inj 120 mg .......................................................................................168.00 Inj 150 mg .......................................................................................192.00 10 10 10 10 10 10 10

Clexane Clexane Clexane Clexane Clexane Clexane Clexane

¾SA1174 Special Authority for Subsidy Initial application — (Pregnancy or Malignancy) from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: Either: 1 Low molecular weight heparin treatment is required during a patients pregnancy; or 2 For the treatment of venous thromboembolism where the patient has a malignancy. Initial application — (Venous thromboembolism other than in pregnancy or malignancy) from any relevant practitioner. Approvals valid for 1 month for applications meeting the following criteria: continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

BLOOD AND BLOOD FORMING ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . Any of the following: 1 For the short-term treatment of venous thromboembolism prior to establishing a therapeutic INR with oral anti-coagulant treatment; or 2 For the prophylaxis and treatment of venous thromboembolism in high risk surgery; or 3 To enable cessation/re-establishment of existing oral anticoagulant treatment pre/post surgery; or 4 For the prophylaxis and treatment of venous thromboembolism in Acute Coronary Syndrome surgical intervention; or 5 To be used in association with cardioversion of atrial ﬁbrillation. Renewal — (Pregnancy or Malignancy) from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: Either: 1 Low molecular weight heparin treatment is required during a patient’s pregnancy; or 2 For the treatment of venous thromboembolism where the patient has a malignancy. Renewal — (Venous thromboembolism other than in pregnancy or malignancy) from any relevant practitioner. Approvals valid for 1 month where low molecular weight heparin treatment or prophylaxis is required for a second or subsequent event (surgery, ACS, cardioversion, or prior to oral anti-coagulation). HEPARIN SODIUM Inj 1,000 iu per ml, 5 ml ....................................................................13.36 10 Mayne 66.80 50 Mayne 11.44 10 Pﬁzer 46.30 50 Pﬁzer Inj 1,000 iu per ml, 35 ml ..................................................................16.00 1 Mayne Inj 5,000 iu per ml, 1 ml ....................................................................14.20 5 Mayne Inj 5,000 iu per ml, 5 ml ..................................................................118.50 50 Pﬁzer Inj 25,000 iu per ml, 0.2 ml .................................................................9.50 5 Mayne HEPARINISED SALINE F Inj 10 iu per ml, 5 ml .........................................................................32.50 PROTAMINE SULPHATE F Inj 10 mg per ml, 5 ml .......................................................................22.40 (95.87) 50 10 Artex

Pﬁzer

Oral Anticoagulants

DABIGATRAN Dabigatran will not be funded Close Control in amounts less than 4 weeks of treatment. Cap 75 mg – No more than 2 cap per day .....................................148.00 60 OP Cap 110 mg ....................................................................................148.00 60 OP Cap 150 mg ....................................................................................148.00 60 OP RIVAROXABAN – Special Authority see SA1066 on the next page – Retail pharmacy Tab 10 mg .......................................................................................153.00 15 306.00 30

Pradaxa Pradaxa Pradaxa Xarelto Xarelto

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

BLOOD AND BLOOD FORMING ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA1066 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 5 weeks for applications meeting the following criteria: Either: 1 For the prophylaxis of venous thromboembolism following a total hip replacement; or 2 For the prophylaxis of venous thromboembolism following a total knee replacement. Note: Rivaroxaban is only currently indicated and subsidised for up to 5 weeks therapy for prophylaxis of venous thromboembolism following a total hip replacement and up to 2 weeks therapy for prophylaxis of venous thromboembolism following a total knee replacement. Renewal from any relevant practitioner. Approvals valid for 5 weeks where prophylaxis for venous thromboembolism is required for patients following a subsequent total hip or knee replacement. WARFARIN SODIUM Note: Marevan and Coumadin are not interchangeable. F Tab 1 mg .............................................................................................3.46 50 Coumadin 5.69 100 Marevan F Tab 2 mg .............................................................................................4.31 50 Coumadin F Tab 3 mg .............................................................................................8.00 100 Marevan F Tab 5 mg .............................................................................................5.93 50 Coumadin 9.64 100 Marevan

Fluids and Electrolytes Intravenous Administration

DEXTROSE F Inj 50%, 10 ml – Up to 5 inj available on a PSO...............................19.50 F Inj 50%, 90 ml – Up to 5 inj available on a PSO...............................11.25 POTASSIUM CHLORIDE F Inj 75 mg per ml, 10 ml .....................................................................55.00 5 1 50

Biomed Biomed AstraZeneca

SODIUM BICARBONATE Inj 8.4%, 50 ml ..................................................................................19.95 1 Biomed a) Up to 5 inj available on a PSO b) Not in combination Inj 8.4%, 100 ml ................................................................................20.50 1 Biomed a) Up to 5 inj available on a PSO b) Not in combination SODIUM CHLORIDE Not funded for use as a nasal drop. Only funded for nebuliser use when in conjunction with an antibiotic intended for nebuliser use. Inf 0.9% – Up to 2000 ml available on a PSO ....................................3.06 500 ml Baxter 4.06 1,000 ml Baxter Only if prescribed on a prescription for renal dialysis, maternity or post-natal care in the home of the patient, or on a PSO for emergency use. (500 ml and 1,000 ml packs) Inj 23.4%, 20 ml ................................................................................31.25 5 Biomed Inj 0.9%, 5 ml – Up to 5 inj available on a PSO................................10.85 50 Multichem 15.50 Pﬁzer Inj 0.9%, 10 ml – Up to 5 inj available on a PSO..............................15.50 50 Pﬁzer 16.10 Multichem Inj 0.9%, 20 ml ....................................................................................4.72 6 Pharmacia 11.79 30 Pharmacia 8.41 20 Multichem

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

BLOOD AND BLOOD FORMING ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

TOTAL PARENTERAL NUTRITION (TPN) – Retail pharmacy-Specialist Infusion .............................................................................................CBS WATER 1) On a prescription or Practitioner’s Supply Order only when on the same form Schedule requiring a solvent or diluent; or 2) On a bulk supply order; or 3) When used in the extemporaneous compounding of eye drops. Puriﬁed for inj, 5 ml – Up to 5 inj available on a PSO .........................9.20 Puriﬁed for inj, 10 ml – Up to 5 inj available on a PSO .....................10.20 Puriﬁed for inj, 20 ml – Up to 5 inj available on a PSO .......................5.00

1 OP

TPN

as an injection listed in the Pharmaceutical

50 50 20

Multichem Multichem Multichem

Oral Administration

CALCIUM POLYSTYRENE SULPHONATE Powder ............................................................................................169.85 COMPOUND ELECTROLYTES Powder for soln for oral use 4.4 g – Up to 10 sach available on a PSO...................................................................................... 1.12 DEXTROSE WITH ELECTROLYTES Soln with electrolytes ..........................................................................6.60 300 g OP

Calcium Resonium

5 1,000 ml OP

Electral Pedialyte Bubblegum

6.75 POTASSIUM BICARBONATE Tab eff 315 mg with sodium acid phosphate 1.937 g and sodium bicarbonate 350 mg ......................................................82.50 For phosphate supplementation POTASSIUM CHLORIDE F Tab eff 548 mg (14 m eq) with chloride 285 mg (8 m eq) ...................5.26 (11.85) F Tab long-acting 600 mg ......................................................................7.00 SODIUM BICARBONATE Cap 840 mg ........................................................................................8.52 SODIUM POLYSTYRENE SULPHONATE Powder ..............................................................................................89.10

Pedialyte - Fruit Pedialyte - Plain

100

Phosphate-Sandoz

60 Chlorvescent 200 100 450 g OP

Span-K Sodibic Resonium-A

Lipid Modifying Agents Fibrates

BEZAFIBRATE F Tab 200 mg .........................................................................................9.75 F Tab long-acting 400 mg ......................................................................5.70 GEMFIBROZIL Tab 600 mg .......................................................................................14.00 90 30 60

Fibalip Bezalip Retard Lipazil

Other Lipid Modifying Agents

ACIPIMOX F Cap 250 mg ......................................................................................18.75 30

Olbetam

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

BLOOD AND BLOOD FORMING ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

NICOTINIC ACID F Tab 50 mg ...........................................................................................4.17 F Tab 500 mg .......................................................................................16.54

100 100

Apo-Nicotinic Acid Apo-Nicotinic Acid

Resins

CHOLESTYRAMINE WITH ASPARTAME Sachets 4 g with aspartame .............................................................19.25 (52.68) COLESTIPOL HYDROCHLORIDE Sachets 5 g .......................................................................................20.00 50 Questran-Lite 30

Colestid

HMG CoA Reductase Inhibitors (Statins)

Prescribing Guidelines Treatment with HMG CoA Reductase Inhibitors (statins) is recommended for patients cardiovascular risk of 15% or greater. ATORVASTATIN – See prescribing guideline below F Tab 10 mg .........................................................................................18.32 F Tab 20 mg .........................................................................................26.70 F Tab 40 mg .........................................................................................37.02 F Tab 80 mg .......................................................................................110.50 PRAVASTATIN – See prescribing guideline below Tab 10 mg ........................................................................................27.46 Tab 20 mg ...........................................................................................5.44 (42.58) Tab 40 mg ...........................................................................................9.28 (65.31) (Pravachol Tab 10 mg to be delisted 1 March 2012) (Pravachol Tab 20 mg to be delisted 1 February 2012) (Pravachol Tab 40 mg to be delisted 1 February 2012) SIMVASTATIN – See prescribing guideline below F Tab 10 mg ...........................................................................................1.40 F Tab 20 mg ...........................................................................................1.95 F Tab 40 mg ...........................................................................................3.18 F Tab 80 mg ...........................................................................................9.31 with dyslipidaemia and an absolute 5 year

30 30 30 30 30 30 30

Lipitor Lipitor Lipitor Lipitor Pravachol Cholvastin

Pravachol

Cholvastin

Pravachol

90 90 90 90

Arrow-Simva 10mg Arrow-Simva 20mg Arrow-Simva 40mg Arrow-Simva 80mg

Selective Cholesterol Absorption Inhibitors

EZETIMIBE – Special Authority see SA1045 below – Retail pharmacy Tab 10 mg .........................................................................................45.90 30

Ezetrol

¾SA1045 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 2 years for applications meeting the following criteria: All of the following: 1 Patient has a calculated absolute risk of cardiovascular disease of at least 15% over 5 years; and 2 Patient’s LDL cholesterol is 2.0 mmol/litre or greater; and 3 Any of the following: 3.1 The patient has rhabdomyolysis (deﬁned as muscle aches and creatine kinase more than 10 × normal) when treated with one statin; or 3.2 The patient is intolerant to both simvastatin and atorvastatin; or continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

BLOOD AND BLOOD FORMING ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 3.3 The patient has not reduced their LDL cholesterol to less than 2.0 mmol/litre with the use of the maximal tolerated dose of atorvastatin. Notes: A patient who has failed to reduce their LDL cholesterol to < 2.0 mmol/litre with the use of a less potent statin should use a more potent statin prior to consideration being given to the use of non-statin therapies. Other treatment options including ﬁbrates, resins and nicotinic acid should be considered after failure of statin therapy. If a patient’s LDL cholesterol cannot be calculated because the triglyceride level is too high then a repeat test should be performed and if the LDL cholesterol again cannot be calculated then it can be considered that the LDL cholesterol is greater than 2.0 mmol/litre. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment. EZETIMIBE WITH SIMVASTATIN – Special Authority see SA1046 below – Retail pharmacy Tab 10 mg with simvastatin 10 mg ...................................................48.90 30 Vytorin Tab 10 mg with simvastatin 20 mg ...................................................51.60 30 Vytorin Tab 10 mg with simvastatin 40 mg ...................................................55.20 30 Vytorin Tab 10 mg with simvastatin 80 mg ...................................................60.60 30 Vytorin ¾SA1046 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 2 years for applications meeting the following criteria: All of the following: 1 Patient has a calculated absolute risk of cardiovascular disease of at least 15% over 5 year; and 2 Patient’s LDL cholesterol is 2.0 mmol/litre or greater; and 3 The patient has not reduced their LDL cholesterol to less than 2.0 mmol/litre with the use of the maximal tolerated dose of atorvastatin. Notes: A patient who has failed to reduce their LDL cholesterol to ≤ 2.0 mmol/litre with the use of a less potent statin should use a more potent statin prior to consideration being given to the use of non-statin therapies. Other treatment options including ﬁbrates, resins and nicotinic acid should be considered after failure of statin therapy. If a patient’s LDL cholesterol cannot be calculated because the triglyceride level is too high then a repeat test should be performed and if the LDL cholesterol again cannot be calculated then it can be considered that the LDL cholesterol is greater than 2.0 mmol/litre. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment.

Iron Overload

DEFERIPRONE – Special Authority see SA1042 below – Retail pharmacy Tab 500 mg .....................................................................................533.17 Oral liq 100 mg per 1 ml .................................................................266.59 100 250 ml OP

Ferriprox Ferriprox

¾SA1042 Special Authority for Subsidy Initial application only from a relevant specialist. Approvals valid without further renewal unless notiﬁed where the patient has been diagnosed with chronic transfusional iron overload due to congenital inherited anaemia. Note: For the purposes of this Special Authority, a relevant specialist is deﬁned as a haematologist. DESFERRIOXAMINE MESYLATE F Inj 500 mg .........................................................................................99.00 10 Mayne

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

CARDIOVASCULAR SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Alpha Adrenoceptor Blockers

DOXAZOSIN MESYLATE F Tab 2 mg .............................................................................................8.23 F Tab 4 mg ...........................................................................................12.40 PHENOXYBENZAMINE HYDROCHLORIDE F Cap 10 mg ..........................................................................................7.82 26.05 PHENTOLAMINE MESYLATE F Inj 10 mg per ml, 1 ml .......................................................................17.97 (31.65) PRAZOSIN HYDROCHLORIDE F Tab 1 mg .............................................................................................5.53 F Tab 2 mg .............................................................................................7.00 F Tab 5 mg ...........................................................................................11.70 TERAZOSIN HYDROCHLORIDE F Tab 1 mg .............................................................................................1.50 F Tab 2 mg .............................................................................................0.80 F Tab 5 mg .............................................................................................1.00 500 500 30 100 5 Regitine 100 100 100 28 28 28

Apo-Doxazosin Apo-Doxazosin Dibenyline S29 Dibenyline S29

Apo-Prazo Apo-Prazo Apo-Prazo Arrow Arrow Arrow

Agents Affecting the Renin-Angiotensin System

Perindopril and trandolapril will be funded to the level of the ex-manufacturer price listed in the Schedule for patients who were taking these ACE inhibitors for the treatment of congestive heart failure prior to 1 June 1998. The prescription must be endorsed accordingly. We recommend that the words used to indicate eligibility are “certiﬁed condition” or an appropriate description of the patient such as “congestive heart failure”, “CHF”, “congestive cardiac failure” or “CCF”. Deﬁnition of Congestive Heart Failure At the request of some prescribers the PTAC Cardiovascular subcommittee has provided a deﬁnition of congestive heart failure for the purposes of the funding of the manufacturer’s surcharge: “Clinicians should use their clinical judgement. Existing patients would be eligible for the funding of the surcharge if the patient shows signs and symptoms of congestive heart failure, and requires or has in the past required concomitant treatment with a diuretic. The deﬁnition could also be considered to include patients post myocardial infarction with an ejection fraction of less than 40%.”

ACE Inhibitors

CAPTOPRIL F Tab 12.5 mg ........................................................................................2.00 F Tab 25 mg ...........................................................................................2.40 F Tab 50 mg ...........................................................................................3.50 F‡ Oral liq 5 mg per ml ..........................................................................94.99 Oral liquid restricted to children under 12 years of age. CILAZAPRIL F Tab 0.5 mg ..........................................................................................0.95 F Tab 2.5 mg ..........................................................................................6.18 F Tab 5 mg .............................................................................................9.84 ENALAPRIL F Tab 5 mg .............................................................................................1.98 F Tab 10 mg ...........................................................................................2.44 F Tab 20 mg – For enalapril oral liquid formulation refer, page 172 ...............................................................................................3.24 100 100 100 95 ml OP

m-Captopril m-Captopril m-Captopril Capoten

30 90 90 90 90 90

Zapril Zapril Zapril Arrow-Enalapril Arrow-Enalapril Arrow-Enalapril

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

CARDIOVASCULAR SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

LISINOPRIL F Tab 5 mg .............................................................................................2.06 F Tab 10 mg ...........................................................................................2.36 F Tab 20 mg ...........................................................................................2.87 PERINDOPRIL F Tab 2 mg – Higher subsidy of $18.50 per 30 tab with Endorsement..................................................................................... 3.00 (18.50) F Tab 4 mg – Higher subsidy of $25.00 per 30 tab with Endorsement..................................................................................... 4.05 (25.00) QUINAPRIL F Tab 5 mg .............................................................................................1.60 F Tab 10 mg ...........................................................................................1.75 F Tab 20 mg ...........................................................................................2.35 TRANDOLAPRIL F Cap 1 mg – Higher subsidy of $18.67 per 28 cap with Endorsement..................................................................................... 3.06 (18.67) F Cap 2 mg – Higher subsidy of $27.00 per 28 cap with Endorsement..................................................................................... 4.43 (27.00)

30 30 30

Arrow-Lisinopril Arrow-Lisinopril Arrow-Lisinopril

30 Coversyl 30 Coversyl 30 30 30

Accupril Accupril Accupril

28 Gopten 28 Gopten

ACE Inhibitors with Diuretics

CILAZAPRIL WITH HYDROCHLOROTHIAZIDE F Tab 5 mg with hydrochlorothiazide 12.5 mg .......................................5.36 ENALAPRIL WITH HYDROCHLOROTHIAZIDE F Tab 20 mg with hydrochlorothiazide 12.5 mg .....................................3.32 (8.70) QUINAPRIL WITH HYDROCHLOROTHIAZIDE F Tab 10 mg with hydrochlorothiazide 12.5 mg .....................................3.37 F Tab 20 mg with hydrochlorothiazide 12.5 mg .....................................4.57 28 30 Co-Renitec 30 30

Inhibace Plus

Accuretic 10 Accuretic 20

Angiotension II Antagonists

CANDESARTAN – Special Authority see SA0933 on the next page – Retail pharmacy F Tab 4 mg – No more than 1.5 tab per day ........................................16.22 48.66 F Tab 8 mg – No more than 1.5 tab per day ........................................19.30 57.90 F Tab 16 mg – No more than 1 tab per day .........................................23.54 70.62 F Tab 32 mg – No more than 1 tab per day .........................................38.50 115.50 30 90 30 90 30 90 30 90

Atacand Candestar Atacand Candestar Atacand Candestar Atacand Candestar

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

CARDIOVASCULAR SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA0933 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Either: 1 Both: 1.1 Patient with congestive heart failure; and 1.2 Either: 1.2.1 Has been treated with, and cannot tolerate, two ACE inhibitors, due to persistent cough; or 1.2.2 Has experienced angioedema on an ACE inhibitor at any time in the past or who have experienced angioedema (even if not using an ACE inhibitor) in the last 2 years; or 2 All of the following: 2.1 Patient with raised blood pressure; and 2.2 Use of fully funded beta blockers or diuretics are contraindicated; or not well tolerated; or insufﬁcient to control blood pressure adequately at appropriate doses; and 2.3 Either: 2.3.1 Has been treated with, and cannot tolerate, two ACE inhibitors, due to persistent cough; or 2.3.2 Has experienced angioedema on an ACE inhibitor at any time in the past or who have experienced angioedema (even if not using an ACE inhibitor) in the last 2 years. LOSARTAN F Tab 12.5 mg ........................................................................................2.88 90 Lostaar 0.96 30 (10.45) Cozaar F Tab 25 mg ...........................................................................................3.20 90 Lostaar 1.07 30 (10.45) Cozaar F Tab 50 mg ...........................................................................................5.22 90 Lostaar 1.74 30 (8.70) Cozaar Tab 50 mg with hydrochlorothiazide 12.5 mg .....................................4.89 30 Arrow-Losartan & Hydrochlorothiazide (10.45) Hyzaar F Tab 100 mg .........................................................................................8.68 90 Lostaar 2.89 30 (10.45) Cozaar (Cozaar Tab 12.5 mg to be delisted 1 March 2012) (Cozaar Tab 25 mg to be delisted 1 March 2012) (Cozaar Tab 50 mg to be delisted 1 March 2012) (Hyzaar Tab 50 mg with hydrochlorothiazide 12.5 mg to be delisted 1 March 2012) (Cozaar Tab 100 mg to be delisted 1 March 2012)

Antiarrhythmics

For lignocaine hydrochloride refer to NERVOUS SYSTEM, Anaesthetics, Local, page 114 AMIODARONE HYDROCHLORIDE L Tab 100 mg – Retail pharmacy-Specialist ........................................18.65 30 L Tab 200 mg – Retail pharmacy-Specialist ........................................30.52 Inj 50 mg per ml, 3 ml – Up to 5 inj available on a PSO ...................60.84 30 10

Aratac Cordarone-X Aratac Cordarone-X Cordarone-X

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

CARDIOVASCULAR SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

DIGOXIN F Tab 62.5 µg – Up to 30 tab available on a PSO..................................5.56 6.67 F Tab 250 µg – Up to 30 tab available on a PSO...................................6.05 14.52 F‡ Oral liq 50 µg per ml .........................................................................16.60 DISOPYRAMIDE PHOSPHATE L Cap 100 mg ......................................................................................15.00 (23.87) L Cap 150 mg ......................................................................................26.21 FLECAINIDE ACETATE – Retail pharmacy-Specialist L Tab 50 mg .........................................................................................45.82 L Tab 100 mg – For ﬂecainide acetate oral liquid formulation refer, page 172 ...........................................................................80.92 L Cap long-acting 100 mg ...................................................................45.82 L Cap long-acting 200 mg ...................................................................80.92 Inj 10 mg per ml, 15 ml .....................................................................52.45 PROPAFENONE HYDROCHLORIDE – Retail pharmacy-Specialist L Tab 150 mg .......................................................................................40.90

200 240 100 240 60 ml 100

Lanoxin PG Lanoxin PG Lanoxin Lanoxin Lanoxin

Rythmodan 100 60 60 30 30 5 50

Rythmodan Tambocor Tambocor Tambocor CR Tambocor CR Tambocor Rytmonorm

Antihypotensives

MIDODRINE – Special Authority see SA0934 below – Retail pharmacy Tab 2.5 mg ........................................................................................53.00 Tab 5 mg ...........................................................................................79.00 100 100

Gutron Gutron

¾SA0934 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 2 years for applications meeting the following criteria: All of the following: 1 Disabling orthostatic hypotension not due to drugs; and 2 Patient has tried ﬂudrocortisone (unless contra-indicated) with unsatisfactory results; and 3 Patient has tried non pharmacological treatments such as support hose, increased salt intake, exercise, and elevation of head and trunk at night. Notes: Treatment should be started with small doses and titrated upwards as necessary. Hypertension should be avoided, and the usual target is a standing systolic blood pressure of 90 mm Hg. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment.

Beta Adrenoceptor Blockers

ATENOLOL F Tab 50 mg ...........................................................................................6.18 12.36 F Tab 100 mg .......................................................................................10.73 21.46 CARVEDILOL Tab 6.25 mg ......................................................................................21.00 Tab 12.5 mg ......................................................................................27.00 Tab 25 mg – For carvedilol oral liquid formulation refer, page 172 .............................................................................................33.75 CELIPROLOL F Tab 200 mg .......................................................................................19.00

fully subsidised [HP4] refer page 9

500 1,000 500 1,000 30 30 30 180

Paciﬁc Atenolol Atenolol Tablet USP Paciﬁc Atenolol Atenolol Tablet USP Dilatrend Dilatrend Dilatrend Celol

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

CARDIOVASCULAR SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

LABETALOL F Tab 50 mg ...........................................................................................8.23 F Tab 100 mg – For labetalol oral liquid formulation refer, page 172 ............................................................................................. 10.06 F Tab 200 mg .......................................................................................17.55 F Inj 5 mg per ml, 20 ml .......................................................................59.06 (88.60) METOPROLOL SUCCINATE F Tab long-acting 23.75 mg ...................................................................2.18

100 100 100 5

Hybloc Hybloc Hybloc

Trandate

F Tab long-acting 47.5 mg .....................................................................2.74

F Tab long-acting 95 mg ........................................................................4.71

F Tab long-acting 190 mg ......................................................................8.51

Betaloc CR Metoprolol - AFT CR Myloc CR Betaloc CR Metoprolol - AFT CR Myloc CR Betaloc CR Metoprolol - AFT CR Myloc CR Betaloc CR Metoprolol - AFT CR Myloc CR

METOPROLOL TARTRATE F Tab 50 mg – For metoprolol tartrate oral liquid formulation refer, page 172 ........................................................................... 16.50 F Tab 100 mg .......................................................................................21.80 F Tab long-acting 200 mg ....................................................................18.40 F Inj 1 mg per ml, 5 ml .........................................................................24.00 24.08 (34.00) NADOLOL F Tab 40 mg .........................................................................................14.97 F Tab 80 mg .........................................................................................22.19 PINDOLOL F Tab 5 mg .............................................................................................5.40 F Tab 10 mg ...........................................................................................9.19 F Tab 15 mg .........................................................................................13.80 PROPRANOLOL F Tab 10 mg ...........................................................................................3.55 F Tab 40 mg ...........................................................................................4.65 F Cap long-acting 160 mg ...................................................................16.06 SOTALOL F Tab 80 mg – For sotalol oral liquid formulation refer, page 172 .........27.50 F Tab 160 mg .......................................................................................10.50 F Inj 10 mg per ml, 4 ml .......................................................................65.39 TIMOLOL MALEATE F Tab 10 mg .........................................................................................10.55

100 60 28 5

Lopresor Lopresor Slow-Lopresor Lopresor

Betaloc

100 100 100 100 100 100 100 100 500 100 5 100

Apo-Nadolol Apo-Nadolol Apo-Pindolol Apo-Pindolol Apo-Pindolol Cardinol Cardinol Cardinol LA Mylan Mylan Sotacor Apo-Timol

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

CARDIOVASCULAR SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Calcium Channel Blockers Dihydropyridine Calcium Channel Blockers (DHP CCBs)

AMLODIPINE F Tab 2.5 mg ..........................................................................................2.45 F Tab 5 mg – For amlodipine oral liquid formulation refer, page 172 ............................................................................................... 2.65 F Tab 10 mg ...........................................................................................4.15 FELODIPINE F Tab long-acting 2.5 mg – No more than 1 tab per day .....................10.38 F Tab long-acting 5 mg ........................................................................10.73 F Tab long-acting 10 mg ......................................................................15.60 ISRADIPINE Cap long-acting 2.5 mg ......................................................................7.50 Cap long-acting 5 mg .........................................................................7.85 NIFEDIPINE F Tab long-acting 10 mg ......................................................................17.72 F Tab long-acting 20 mg ........................................................................7.30 F Tab long-acting 30 mg ........................................................................8.56 5.50 (19.90) F Tab long-acting 60 mg ......................................................................12.28 8.00 (29.50) 100 100 100 30 90 90 30 30 60 100 30

Apo-Amlodipine Apo-Amlodipine Apo-Amlodipine Plendil ER Felo 5 ER Felo 10 ER Dynacirc-SRO Dynacirc-SRO Adalat 10 Nyefax Retard Adeﬁn XL Arrow-Nifedipine XR

Adalat Oros

Adeﬁn XL Arrow-Nifedipine XR

Adalat Oros

Other Calcium Channel Blockers

DILTIAZEM HYDROCHLORIDE F Tab 30 mg ...........................................................................................4.60 F Tab 60 mg – For diltiazem hydrochloride oral liquid formulation refer, page 172....................................................................... 8.50 F Cap long-acting 120 mg .....................................................................4.34 F Cap long-acting 180 mg .....................................................................6.50 F Cap long-acting 240 mg .....................................................................8.67 100 100 30 30 30

Dilzem Dilzem Cardizem CD Cardizem CD Cardizem CD Pexsig

PERHEXILINE MALEATE – Special Authority see SA0256 below – Retail pharmacy F Tab 100 mg .......................................................................................62.90 100

¾SA0256 Special Authority for Subsidy Initial application only from a cardiologist or general physician. Approvals valid for 2 years for applications meeting the following criteria: Both: 1 Refractory angina; and 2 Patient is already on maximal anti-anginal therapy. Renewal only from a cardiologist or general physician. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment.

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

CARDIOVASCULAR SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

VERAPAMIL HYDROCHLORIDE F Tab 40 mg ...........................................................................................7.01 F Tab 80 mg – For verapamil hydrochloride oral liquid formulation refer, page 172..................................................................... 11.74 F Tab long-acting 120 mg ....................................................................15.20 F Tab long-acting 240 mg ....................................................................25.00 F Inj 2.5 mg per ml, 2 ml – Up to 5 inj available on a PSO ....................7.54

100 100 250 250 5

Isoptin Isoptin Verpamil SR Verpamil SR Isoptin

Centrally Acting Agents

CLONIDINE F TDDS 2.5 mg, 100 µg per day – Only on a prescription...................23.30 F TDDS 5 mg, 200 µg per day – Only on a prescription......................32.80 F TDDS 7.5 mg, 300 µg per day – Only on a prescription...................41.20 CLONIDINE HYDROCHLORIDE F Tab 150 µg ........................................................................................33.00 F Inj 150 µg per ml, 1 ml ......................................................................15.45 METHYLDOPA F Tab 125 mg .......................................................................................12.00 F Tab 250 mg .......................................................................................13.10 F Tab 500 mg .......................................................................................20.85 4 4 4 100 5 100 100 100

Catapres-TTS-1 Catapres-TTS-2 Catapres-TTS-3 Catapres Catapres Prodopa Prodopa Prodopa

Diuretics Loop Diuretics

BUMETANIDE F Tab 1 mg ...........................................................................................16.36 F Inj 500 µg per ml, 4 ml ........................................................................7.95 FUROSEMIDE F Tab 40 mg – Up to 30 tab available on a PSO..................................10.75 F Tab 500 mg .......................................................................................25.00 F‡ Oral liq 10 mg per ml ........................................................................10.66 F Infusion 10 mg per ml, 25 ml ............................................................48.14 F Inj 10 mg per ml, 2 ml – Up to 5 inj available on a PSO .....................1.30 100 5 1,000 50 30 ml OP 5 5

Burinex Burinex Diurin 40 Urex Forte Lasix Lasix Frusemide-Claris

Potassium Sparing Diuretics

AMILORIDE ‡ Oral liq 1 mg per ml ..........................................................................26.20 SPIRONOLACTONE F Tab 25 mg ...........................................................................................4.60 F Tab 100 mg .......................................................................................15.15 ‡ Oral liq 5 mg per ml ..........................................................................26.80 25 ml OP 100 100 25 ml OP

Biomed Spirotone Spirotone Biomed

Potassium Sparing Combination Diuretics

AMILORIDE WITH FRUSEMIDE F Tab 5 mg with frusemide 40 mg .........................................................8.63 AMILORIDE WITH HYDROCHLOROTHIAZIDE F Tab 5 mg with hydrochlorothiazide 50 mg ..........................................5.00 28 50

Frumil Moduretic

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

CARDIOVASCULAR SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Thiazide and Related Diuretics

BENDROFLUAZIDE F Tab 2.5 mg – Up to 150 tab available on a PSO.................................6.48 May be supplied on a PSO for reasons other than emergency. F Tab 5 mg .............................................................................................9.95 CHLOROTHIAZIDE ‡ Oral liq 50 mg per ml ........................................................................22.60 CHLORTHALIDONE F Tab 25 mg ...........................................................................................8.00 INDAPAMIDE F Tab 2.5 mg ..........................................................................................2.95 500 500

ArrowBendroﬂuazide

25 ml OP 50 90

Biomed Hygroton Dapa-Tabs

Nitrates

GLYCERYL TRINITRATE F Tab 600 µg – Up to 100 tab available on a PSO.................................8.00 F Oral pump spray 400 µg per dose – Up to 250 dose available on a PSO...................................................................................... 5.16 F TDDS 5 mg .......................................................................................16.56 F TDDS 10 mg .....................................................................................19.50 ISOSORBIDE MONONITRATE F Tab 20 mg .........................................................................................17.10 F Tab long-acting 40 mg ........................................................................7.50 F Tab long-acting 60 mg ........................................................................3.94 100 OP 250 dose OP 30 30 100 30 90

Lycinate Nitrolingual

Pumpspray

Nitroderm TTS Nitroderm TTS Ismo 20 Corangin Duride

Sympathomimetics

ADRENALINE Inj 1 in 1,000, 1 ml – Up to 5 inj available on a PSO ..........................4.98 5.25 Inj 1 in 10,000, 10 ml – Up to 5 inj available on a PSO ....................27.00 ISOPRENALINE HYDROCHLORIDE F Inj 200 µg per ml, 1 ml ......................................................................36.80 (135.00) 5 5 25 Isuprel

Aspen Adrenaline Mayne Mayne

Vasodilators

AMYL NITRITE F Ampoule, 0.3 ml crushable ...............................................................62.92 (73.40) HYDRALAZINE F Inj 20 mg per ml, 1 ml .......................................................................25.90 OXYPENTIFYLLINE Tab 400 mg .......................................................................................36.94 (42.26) PAPAVERINE HYDROCHLORIDE F Inj 12 mg per ml, 10 ml .....................................................................73.12

fully subsidised [HP4] refer page 9

12 Baxter 5 50 Trental 400 5

Apresoline

Mayne

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

CARDIOVASCULAR SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Endothelin Receptor Antagonists

¾SA0967 Special Authority for Subsidy Special Authority approved by the Pulmonary Arterial Hypertension Panel Notes: Application details may be obtained from PHARMAC’s website http://www.pharmac.govt.nz or: The Coordinator, PAH Panel PHARMAC, PO Box 10-254, WELLINGTON Tel: (04) 916 7512, Fax: (04) 974 4858, Email: PAH@pharmac.govt.nz AMBRISENTAN – Special Authority see SA0967 above – Retail pharmacy Tab 5 mg ......................................................................................4,585.00 Tab 10 mg ....................................................................................4,585.00 BOSENTAN – Special Authority see SA0967 above – Retail pharmacy Tab 62.5 mg .................................................................................4,585.00 Tab 125 mg ..................................................................................4,585.00 30 30 60 60

Volibris Volibris Tracleer Tracleer

Phosphodiesterase Type 5 Inhibitors

¾SA1086 Special Authority for Subsidy Special Authority approved by the Pulmonary Arterial Hypertension Panel Notes: Application details may be obtained from PHARMAC’s website http://www.pharmac.govt.nz or: The Coordinator, PAH Panel PHARMAC, PO Box 10-254, WELLINGTON Tel: (04) 916 7512, Fax: (04) 974 4858, Email: PAH@pharmac.govt.nz SILDENAFIL – Special Authority see SA1086 above – Retail pharmacy Tab 25 mg .........................................................................................39.00 Tab 50 mg .........................................................................................43.50 Tab 100 mg – For sildenaﬁl oral liquid formulation refer, page 172 ............................................................................................. 47.00 4 4 4

Viagra Viagra Viagra

Prostacyclin Analogues

¾SA0969 Special Authority for Subsidy Special Authority approved by the Pulmonary Arterial Hypertension Panel Notes: Application details may be obtained from PHARMAC’s website http://www.pharmac.govt.nz or: The Coordinator, PAH Panel PHARMAC, PO Box 10-254, WELLINGTON Tel: (04) 916 7512, Fax: (04) 974 4858, Email: PAH@pharmac.govt.nz ILOPROST – Special Authority see SA0969 above – Retail pharmacy Nebuliser soln 10 µg per ml, 2 ml ................................................1,185.00 30

Ventavis

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

DERMATOLOGICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Antiacne Preparations

For systemic antibacterials, refer to INFECTIONS, Antibacterials, page 79 ADAPALENE a) Maximum of 30 g per prescription b) Only on a prescription Crm 0.1% .........................................................................................22.89 Gel 0.1% ...........................................................................................22.89 ISOTRETINOIN – Special Authority see SA0955 below – Retail pharmacy Cap 10 mg ........................................................................................48.48 Cap 20 mg ........................................................................................69.70

30 g OP 30 g OP 180 180

Differin Differin Oratane Oratane

¾SA0955 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 Patient has had an adequate trial on other available treatments and has received an inadequate response from these treatments or these are contraindicated; and 2 Applicant is a vocationally registered dermatologist, vocationally registered general practitioner, or nurse practitioner working in a relevant scope of practice; and 3 Applicant has an up to date knowledge of the treatment options for acne and is aware of the safety issues around isotretinoin and is competent to prescribe isotretinoin; and 4 Either: 4.1 Patient is female and has been counselled and understands the risk of teratogenicity if isotretinoin is used during pregnancy and the applicant has ensured that the possibility of pregnancy has been excluded prior to the commencement of the treatment and that the patient is informed that she must not become pregnant during treatment and for a period of one month after the completion of the treatment; or 4.2 Patient is male. Note: Applicants are recommended to either have used or be familiar with using a decision support tool accredited by their professional body. Renewal from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 Patient has had an adequate trial on other available treatments and has received an inadequate response from these treatments or these are contraindicated; and 2 Applicant is a vocationally registered dermatologist, vocationally registered general practitioner, or nurse practitioner working in a relevant scope of practice; and 3 Applicant has an up to date knowledge of the treatment options for acne and is aware of the safety issues around isotretinoin and is competent to prescribe isotretinoin; and 4 Either: 4.1 Patient is female and has been counselled and understands the risk of teratogenicity if isotretinoin is used during pregnancy and the applicant has ensured that the possibility of pregnancy has been excluded prior to the commencement of the treatment and that the patient is informed that she must not become pregnant during treatment and for a period of one month after the completion of the treatment; or 4.2 Patient is male. Note: Applicants are recommended to either have used or be familiar with using a decision support tool accredited by their professional body. TRETINOIN Crm 0.5 mg per g – Maximum of 50 g per prescription ....................13.90 50 g OP ReTrieve

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

DERMATOLOGICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Antibacterials Topical

For systemic antibacterials, refer to INFECTIONS, Antibacterials, page 79 FUSIDIC ACID Crm 2% .............................................................................................3.25 a) Maximum of 15 g per prescription b) Only on a prescription c) Not in combination Oint 2% ..............................................................................................3.25 a) Maximum of 15 g per prescription b) Only on a prescription c) Not in combination HYDROGEN PEROXIDE F Crm 1% ..............................................................................................8.56 MUPIROCIN Oint 2% ...............................................................................................6.60 (9.26) a) Only on a prescription b) Not in combination SILVER SULPHADIAZINE Crm 1% ............................................................................................12.30 a) Up to 250 g available on a PSO b) Not in combination

15 g OP

Foban

15 g OP

Foban

10 g OP 15 g OP

Crystacide

Bactroban

50 g OP

Flamazine

Antifungals Topical

For systemic antifungals, refer to INFECTIONS, Antifungals, page 84 AMOROLFINE a) Only on a prescription b) Not in combination Nail soln 5% ......................................................................................37.86 (61.87) CICLOPIROXOLAMINE a) Only on a prescription b) Not in combination Nail soln 8% ......................................................................................19.85 Soln 1% ..............................................................................................4.36 (11.54) CLOTRIMAZOLE F Crm 1% ..............................................................................................0.54 a) Only on a prescription b) Not in combination F Soln 1% ..............................................................................................4.36 (7.55) a) Only on a prescription b) Not in combination

5 ml OP Loceryl

3.5 ml OP 20 ml OP

Batrafen

20 g OP

Clomazol

20 ml OP Canesten

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

DERMATOLOGICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

ECONAZOLE NITRATE Crm 1% ..............................................................................................1.00 (7.48) a) Only on a prescription b) Not in combination Foaming soln 1%, 10 ml sachets ........................................................9.89 (17.23) a) Only on a prescription b) Not in combination MICONAZOLE NITRATE F Crm 2% ..............................................................................................0.46 a) Only on a prescription b) Not in combination F Lotn 2% ..............................................................................................4.36 (10.03) a) Only on a prescription b) Not in combination F Tinct 2% ..............................................................................................4.36 (12.10) a) Only on a prescription b) Not in combination NYSTATIN Crm 100,000 u per g ..........................................................................1.00 (7.90) a) Only on a prescription b) Not in combination

20 g OP Pevaryl

3 Pevaryl

15 g OP

Multichem

30 ml OP Daktarin

15 g OP Mycostatin

Antipruritic Preparations

CALAMINE a) Only on a prescription b) Not in combination Crm, aqueous, BP ..............................................................................2.78 Lotn, BP ............................................................................................16.70 CROTAMITON a) Only on a prescription b) Not in combination Crm 10% ............................................................................................3.79

100 g 2,000 ml

healthE API

20 g OP

Itch-Soothe

MENTHOL – Only in combination Only in combination with aqueous cream, 10% urea cream, wool fat with mineral oil lotion, 1% hydrocortisone with wool fat and mineral oil lotion, and glycerol, parafﬁn and cetyl alcohol lotion Crystals ..............................................................................................6.50 25 g PSM 6.92 MidWest 29.60 100 g MidWest

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

DERMATOLOGICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Corticosteroids Topical

For systemic corticosteroids, refer to CORTICOSTEROIDS AND RELATED AGENTS, page 72

Corticosteroids - Plain

BETAMETHASONE DIPROPIONATE Crm 0.05% .........................................................................................2.96 (6.91) 8.97 (18.36) Crm 0.05% in propylene glycol base ..................................................4.33 (13.83) Oint 0.05% ..........................................................................................2.96 (6.51) 8.97 (17.11) Oint 0.05% in propylene glycol base ..................................................4.33 (13.83) BETAMETHASONE VALERATE F Crm 0.1% ...........................................................................................3.20 F Oint 0.1% ............................................................................................3.20 F Lotn 0.1% .........................................................................................10.05 CLOBETASOL PROPIONATE F Crm 0.05% .........................................................................................3.48 F Oint 0.05% ..........................................................................................3.48 CLOBETASONE BUTYRATE Crm 0.05% .........................................................................................5.38 (7.09) 16.13 (22.00) DIFLUCORTOLONE VALERATE Crm 0.1% ...........................................................................................8.97 (15.86) Fatty oint 0.1% ....................................................................................8.97 (15.86) 15 g OP Diprosone 50 g OP Diprosone 30 g OP Diprosone OV 15 g OP Diprosone 50 g OP Diprosone 30 g OP Diprosone OV 50 g OP 50 g OP 50 ml OP 30 g OP 30 g OP 30 g OP Eumovate 100 g OP Eumovate 50 g OP Nerisone 50 g OP Nerisone

Beta Cream Beta Ointment Betnovate Dermol Dermol

HYDROCORTISONE F Crm 1% – Only on a prescription .....................................................14.00 500 g F Powder – Only in combination .........................................................44.00 25 g Up to 5% in a dermatological base (not proprietary Topical Corticosteriod – Plain) with galenicals. Refer, page 171 HYDROCORTISONE BUTYRATE Lipocream 0.1% ..................................................................................2.30 30 g OP 6.85 100 g OP Oint 0.1% ............................................................................................6.85 100 g OP Milky emul 0.1% .................................................................................6.85 100 ml OP HYDROCORTISONE WITH WOOL FAT AND MINERAL OIL Lotn 1% with wool fat hydrous 3% and mineral oil – Only on a prescription................................................................................9.95

Pharmacy Health ABM

or without other dermatological

Locoid Lipocream Locoid Lipocream Locoid Locoid Crelo

250 ml

DP Lotn HC

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

DERMATOLOGICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

METHYLPREDNISOLONE ACEPONATE Crm 0.1% ...........................................................................................4.95 Oint 0.1% ............................................................................................4.95 MOMETASONE FUROATE Crm 0.1% ...........................................................................................2.38 4.55 Oint 0.1% ............................................................................................2.38 4.55 Lotn 0.1% ...........................................................................................7.35 TRIAMCINOLONE ACETONIDE Crm 0.02% .........................................................................................6.63 Oint 0.02% ..........................................................................................6.69

15 g OP 15 g OP 15 g OP 45 g OP 15 g OP 45 g OP 30 ml OP 100 g OP 100 g OP

Advantan Advantan m-Mometasone m-Mometasone m-Mometasone m-Mometasone Elocon Aristocort Aristocort

Corticosteroids - Combination

BETAMETHASONE VALERATE WITH CLIOQUINOL – Only on a prescription Crm 0.1% with clioquinol 3% ..............................................................3.49 (4.90) Oint 0.1% with clioquinol 3% ..............................................................3.49 (4.90) BETAMETHASONE VALERATE WITH FUSIDIC ACID Crm 0.1% with fusidic acid 2% ...........................................................3.49 (10.45) a) Maximum of 15 g per prescription b) Only on a prescription HYDROCORTISONE WITH MICONAZOLE – Only on a prescription F Crm 1% with miconazole nitrate 2% ...................................................2.10 15 g OP Betnovate-C 15 g OP Betnovate-C 15 g OP Fucicort

15 g OP

Micreme H Pimafucort Pimafucort

HYDROCORTISONE WITH NATAMYCIN AND NEOMYCIN – Only on a prescription Crm 1% with natamycin 1% and neomycin sulphate 0.5% ................2.79 15 g OP Oint 1% with natamycin 1% and neomycin sulphate 0.5% .................2.79 15 g OP TRIAMCINOLONE ACETONIDE WITH GRAMICIDIN, NEOMYCIN AND NYSTATIN Crm 1 mg with nystatin 100,000 u, neomycin sulphate 2.5 mg and gramicidin 250 µg per g – Only on a prescription ................. 3.49 15 g OP (6.60)

Viaderm KC

Disinfecting and Cleansing Agents

CHLORHEXIDINE GLUCONATE – Subsidy by endorsement a) No more than 500 ml per month b) Only if prescribed for a dialysis patient and the prescription is endorsed accordingly. F Handrub 1% with ethanol 70% ...........................................................4.60 500 ml F Soln 4% ..............................................................................................5.90 500 ml

healthE Orion

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

DERMATOLOGICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

TRICLOSAN – Subsidy by endorsement a) Maximum of 500 ml per prescription b) a) Only if prescribed for a patient identiﬁed with Methicillin-resistant Staphylococcus aureus (MRSA) prior to elective surgery in hospital and the prescription is endorsed accordingly; or b) Only if prescribed for a patient with recurrent Staphylococcus aureus infection and the prescription is endorsed accordingly Soln 1% ..............................................................................................4.50 500 ml OP Pharmacy Health 5.90 healthE

Barrier Creams and Emollients Barrier Creams

ZINC AND CASTOR OIL Oint BP ...............................................................................................5.11 500 g

PSM

Emollients

AQUEOUS CREAM F Crm .....................................................................................................1.96 CETOMACROGOL F Crm BP ...............................................................................................3.15 EMULSIFYING OINTMENT F Oint BP ...............................................................................................3.04 OIL IN WATER EMULSION F Crm .....................................................................................................2.80 UREA F Crm 10% ............................................................................................3.07 WOOL FAT WITH MINERAL OIL – Only on a prescription F Lotn hydrous 3% with mineral oil ........................................................1.40 (3.50) 5.60 (10.90) 1.40 (3.50) 5.60 (9.54) (20.53) 1.40 (7.73) 5.60 (23.91) 500 g 500 g 500 g 500 g 100 g OP 250 ml OP DP Lotion 1,000 ml DP Lotion 250 ml OP Hydroderm Lotion 1,000 ml Hydroderm Lotion Alpha-Keri Lotion 250 ml OP BK Lotion 1,000 ml BK Lotion

AFT PSM AFT healthE Fatty Cream Nutraplus

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

DERMATOLOGICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Other Dermatological Bases

PARAFFIN White soft – Only in combination .......................................................3.58 500 g (7.78) IPW 20.20 2,500 g IPW 3.58 500 g (8.69) PSM Only in combination with a dermatological galenical or as a diluent for a proprietary Topical Corticosteroid – Plain.

Minor Skin Infections

POVIDONE IODINE Oint 10% .............................................................................................3.27 a) Maximum of 100 g per prescription b) Only on a prescription Antiseptic soln 10% ............................................................................0.19 (3.27) 1.28 (6.01) 6.20 1.28 (4.20) 6.20 Skin preparation, povidone iodine 10% with 30% alcohol ..................1.63 (3.60) 10.00 Skin preparation, povidone iodine 10% with 70% alcohol ..................1.63 (6.04) 8.13 (18.63) 25 g OP

Betadine

15 ml Betadine 100 ml Betadine 500 ml 100 ml 500 ml 100 ml 500 ml 100 ml 500 ml Orion

Betadine

Riodine

Betadine Skin Prep

Orion

Parasiticidal Preparations

GAMMA BENZENE HEXACHLORIDE Crm 1% ..............................................................................................3.50 MALATHION Liq 0.5% ..............................................................................................3.79 Shampoo 1% ......................................................................................2.83 PERMETHRIN Crm 5% ..............................................................................................4.20 Lotn 5% ..............................................................................................3.24 50 g OP 200 ml OP 30 ml OP 30 g OP 30 ml OP

Benhex A-Lices A-Lices Lyderm A-Scabies

Psoriasis and Eczema Preparations

ACITRETIN – Special Authority see SA0954 on the next page – Retail pharmacy Cap 10 mg ........................................................................................38.66 75.80 Cap 25 mg ........................................................................................83.11 162.96 60 100 60 100

Novatretin Neotigason Novatretin Neotigason

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

DERMATOLOGICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA0954 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 Applicant is a vocationally registered dermatologist, vocationally registered general practitioner, or nurse practitioner working in a relevant scope of practice; and 2 Applicant has an up to date knowledge of the treatment options for psoriasis and of disorders of keratinisation and is aware of the safety issues around acitretin and is competent to prescribe acitretin; and 3 Either: 3.1 Patient is female and has been counselled and understands the risk of teratogenicity if acitretin is used during pregnancy and the applicant has ensured that the possibility of pregnancy has been excluded prior to the commencement of the treatment and that the patient is informed that she must not become pregnant during treatment and for a period of two years after the completion of the treatment; or 3.2 Patient is male. Renewal from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 Applicant is a vocationally registered dermatologist, vocationally registered general practitioner, or nurse practitioner working in a relevant scope of practice; and 2 Applicant has an up to date knowledge of the treatment options for psoriasis and of disorders of keratinisation and is aware of the safety issues around acitretin and is competent to prescribe acitretin; and 3 Either: 3.1 Patient is female and has been counselled and understands the risk of teratogenicity if acitretin is used during pregnancy and the applicant has ensured that the possibility of pregnancy has been excluded prior to the commencement of the treatment and that the patient is informed that she must not become pregnant during treatment and for a period of two years after the completion of the treatment; or 3.2 Patient is male. BETAMETHASONE DIPROPIONATE WITH CALCIPOTRIOL Oint 500 µg with calcipotriol 50 µg ...................................................26.12 30 g OP Daivobet Topical gel 500 µg with calcipotriol 50 µg .........................................26.12 30 g OP Daivobet CALCIPOTRIOL Crm 50 µg per g ...............................................................................16.00 45.00 Oint 50 µg per g ................................................................................20.20 45.00 Soln 50 µg per ml .............................................................................16.00 33.79 30 g OP 100 g OP 30 g OP 100 g OP 30 ml OP 60 ml OP

Daivonex Daivonex Daivonex Daivonex Daivonex Daivonex

COAL TAR Soln BP – Only in combination ........................................................12.95 200 ml Midwest Up to 10 % Only in combination with a dermatological base or proprietary Topical Corticosteriod – Plain, refer, page 171 With or without other dermatological galenicals. COAL TAR WITH ALLANTOIN, MENTHOL, PHENOL AND SULPHUR Soln 5% with sulphur 0.5%, menthol 0.75%, phenol 0.5% and allantoin crm 2.5% .......................................................................3.43 30 g OP (4.35) Egopsoryl TA 6.59 75 g OP (8.00) Egopsoryl TA COAL TAR WITH SALICYLIC ACID AND SULPHUR Soln 12% with salicylic acid 2% and sulphur 4% oint .........................7.95 40 g OP

Coco-Scalp

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

DERMATOLOGICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

SALICYLIC ACID Powder – Only in combination .........................................................18.88 250 g PSM 1) Only in combination with a dermatological base or proprietary Topical Corticosteroid – Plain or collodion ﬂexible, refer, page 171 2) With or without other dermatological galenicals. 3) Maximum 20 g or 20 ml per prescription when prescribed with white soft parafﬁn or collodion ﬂexible. SULPHUR Precipitated – Only in combination ....................................................6.35 100 g Midwest 1) Only in combination with a dermatological base or proprietary Topical Corticosteroid – Plain, refer, page 171 2) With or without other dermatological galenicals. TAR WITH TRIETHANOLAMINE LAURYL SULPHATE AND FLUORESCEIN – Only on a prescription F Soln 2.3% with triethanolamine lauryl sulphate and ﬂuorescein sodium ................................................................................. 3.05 500 ml Pinetarsol 5.82 1,000 ml Pinetarsol

Scalp Preparations

BETAMETHASONE VALERATE F Scalp app 0.1% ..................................................................................7.22 CLOBETASOL PROPIONATE F Scalp app 0.05% ................................................................................6.36 HYDROCORTISONE BUTYRATE Scalp lotn 0.1% ...................................................................................3.65 KETOCONAZOLE Shampoo 2% ......................................................................................3.08 a) Maximum of 100 ml per prescription b) Only on a prescription 100 ml OP 30 ml OP 100 ml OP 100 ml OP

Beta Scalp Dermol Locoid Sebizole

Sunscreens

SUNSCREENS, PROPRIETARY – Subsidy by endorsement Only if prescribed for a patient with severe photosensitivity secondary to a deﬁned clinical condition and the prescription is endorsed accordingly. Crm .....................................................................................................2.55 100 g OP (5.89) Hamilton Sunscreen Lotn ....................................................................................................2.55 100 ml OP Marine Blue Lotion SPF 30+ 5.10 200 ml OP Marine Blue Lotion SPF 30+ 3.19 125 ml OP (6.94) Aquasun 30+

Wart Preparations

For salicylic acid preparations refer to PSORIASIS AND ECZEMA PREPARATIONS, page 62 IMIQUIMOD – Special Authority see SA0923 on the next page – Retail pharmacy Crm 5% ............................................................................................62.00 12

Aldara

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

DERMATOLOGICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA0923 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 4 months for applications meeting the following criteria: Any of the following: 1 The patient has external anogenital warts and podophyllotoxin has been tried and failed (or is contraindicated); or 2 The patient has external anogenital warts and podophyllotoxin is unable to be applied accurately to the site; or 3 The patient has conﬁrmed superﬁcial basal cell carcinoma where other standard treatments, including surgical excision, are contraindicated or inappropriate. Notes: Superﬁcial basal cell carcinoma G Surgical excision remains ﬁrst-line treatment for superﬁcial basal cell carcinoma as it has a higher cure rate than imiquimod and allows histological assessment of tumour clearance. G Imiquimod has not been evaluated for the treatment of superﬁcial basal cell carcinoma within 1 cm of the hairline, eyes, nose, mouth or ears. G Imiquimod is not indicated for recurrent, invasive, inﬁltrating, or nodular basal cell carcinoma. External anogenital warts G Imiquimod is only indicated for external genital and perianal warts (condyloma acuminata). Renewal from any relevant practitioner. Approvals valid for 4 months for applications meeting the following criteria: Any of the following: 1 Inadequate response to initial treatment for anogenital warts; or 2 New conﬁrmed superﬁcial basal cell carcinoma where other standard treatments, including surgical excision, are contraindicated or inappropriate; or 3 Inadequate response to initial treatment for superﬁcial basal cell carcinoma. Note: Every effort should be made to biopsy the lesion to conﬁrm that it is a superﬁcial basal cell carcinoma. PODOPHYLLOTOXIN Soln 0.5% .........................................................................................33.60 3.5 ml OP Condyline a) Maximum of 3.5 ml per prescription b) Only on a prescription

Other Skin Preparations Antineoplastics

FLUOROURACIL SODIUM Crm 5% ............................................................................................26.49 20 g OP

Efudix

Topical Analgesia

For aspirin & chloroform application refer, page 175 CAPSAICIN – Subsidy by endorsement Subsidised only if prescribed for post-herpetic neuralgia or diabetic peripheral neuropathy and the prescription is endorsed accordingly. Crm 0.075% .....................................................................................12.50 45 g OP Zostrix HP

Wound Management Products

MAGNESIUM SULPHATE Paste ..................................................................................................2.98 (4.90) 80 g PSM

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

GENITO-URINARY SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Contraceptives - Non-hormonal Condoms

CONDOMS F 49 mm – Up to 144 dev available on a PSO.......................................1.11 13.36 12 144

F 52 mm – Up to 144 dev available on a PSO.....................................13.36

144

F 52 mm extra strength – Up to 144 dev available on a PSO..............13.36 F 53 mm – Up to 144 dev available on a PSO.......................................1.11 13.36 1.11 13.36

144 12 144 12 144

F 53 mm (chocolate) – Up to 144 dev available on a PSO....................1.11 13.36 F 53 mm (strawberry) – Up to 144 dev available on a PSO ..................1.11 13.36 F 53 mm extra strength – Up to 144 dev available on a PSO................1.11 13.36 F 54 mm, shaped – Up to 144 dev available on a PSO.........................1.12 (1.24) 13.36 (14.84) F 55 mm – Up to 144 dev available on a PSO.......................................1.11 13.36 F 56 mm – Up to 144 dev available on a PSO.....................................13.36

12 144 12 144 12 144 12 144

Gold Knight Gold Knight MarquisTantiliza Shield 49 Marquis Selecta Marquis Sensolite Marquis Supalite Marquis Protecta Shield Blue Shield Blue Gold Knight Gold Knight Marquis Black Marquis Titillata Gold Knight Gold Knight Gold Knight Gold Knight Gold Knight Gold Knight

Lifestyles Flared Lifestyles Flared

12 144 144

Gold Knight Gold Knight Marquis Conforma Durex Extra Safe Durex Select

Flavours

F 56 mm, shaped – Up to 144 dev available on a PSO.........................1.11 13.36 F 60 mm – Up to 144 dev available on a PSO.....................................13.36

12 144 144

Durex Conﬁdence Durex Conﬁdence Shield XL

Contraceptive Devices

DIAPHRAGM – Up to 1 dev available on a PSO One of each size is permitted on a PSO. F 65 mm ...............................................................................................42.90 F 70 mm ...............................................................................................42.90 F 75 mm ...............................................................................................42.90 F 80 mm ...............................................................................................42.90 INTRA-UTERINE DEVICE a) Up to 40 dev available on a PSO b) Only on a PSO F IUD ...................................................................................................39.50

1 1 1 1

Ortho All-ﬂex Ortho All-ﬂex Ortho All-ﬂex Ortho All-ﬂex

Multiload Cu 375 Multiload Cu 375 SL

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

GENITO-URINARY SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Contraceptives - Hormonal Combined Oral Contraceptives

¾SA0500 Special Authority for Alternate Subsidy Initial application from any medical practitioner. Approvals valid for 2 years for applications meeting the following criteria: Both: 1 Either: 1.1 Patient is on a Social Welfare beneﬁt; or 1.2 Patient has an income no greater than the beneﬁt; and 2 Has tried at least one of the fully funded options and has been unable to tolerate it. Renewal from any medical practitioner. Approvals valid for 2 years for applications meeting the following criteria: Either: 1 Patient is on a Social Welfare beneﬁt; or 2 Patient has an income no greater than the beneﬁt. Notes: The approval numbers of Special Authorities approved after 1 November 1999 are interchangeable between Mercilon and Marvelon. The additional subsidy will fund Mercilon and Marvelon up to the manufacturer’s price for each of these products as identiﬁed on the Schedule at 1 November 1999. Special Authorities approved before 1 November 1999 remain valid until the expiry date and can be renewed providing that women are still either: G on a Social Welfare beneﬁt; or G have an income no greater than the beneﬁt. The approval numbers of Special Authorities approved before 1 November 1999 are interchangeable for products within the combined oral contraceptives and progestogen-only contraceptives groups, except Loette and Microgynon 20 ED ETHINYLOESTRADIOL WITH DESOGESTREL F Tab 20 µg with desogestrel 150 µg .....................................................6.62 63 (16.50) Mercilon 21 a) Higher subsidy of $13.80 per 63 tab with Special Authority see SA0500 above b) Up to 63 tab available on a PSO F Tab 20 µg with desogestrel 150 µg and 7 inert tab .............................6.62 84 (16.50) Mercilon 28 a) Higher subsidy of $13.80 per 84 tab with Special Authority see SA0500 above b) Up to 84 tab available on a PSO F Tab 30 µg with desogestrel 150 µg .....................................................6.62 63 (16.50) Marvelon 21 a) Higher subsidy of $13.80 per 63 tab with Special Authority see SA0500 above b) Up to 63 tab available on a PSO F Tab 30 µg with desogestrel 150 µg and 7 inert tab .............................6.62 84 (16.50) Marvelon 28 a) Higher subsidy of $13.80 per 84 tab with Special Authority see SA0500 above b) Up to 84 tab available on a PSO

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

GENITO-URINARY SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

ETHINYLOESTRADIOL WITH LEVONORGESTREL F Tab 50 µg with levonorgestrel 125 µg and 7 inert tab – Up to 84 tab available on a PSO............................................................ 9.45 84 Microgynon 50 ED F Tab 30 µg with levonorgestrel 150 µg .................................................6.62 63 (16.50) Microgynon 30 a) Higher subsidy of $15.00 per 63 tab with Special Authority see SA0500 on the preceding page b) Up to 63 tab available on a PSO F Tab 30 µg with levonorgestrel 150 µg and 7 inert tab .........................6.62 84 Levlen ED Monofeme (14.49) Nordette 28 (16.50) Microgynon 30 ED a) Higher subsidy of up to $15.00 per 84 tab with Special Authority see SA0500 on the preceding page b) Up to 84 tab available on a PSO ETHINYLOESTRADIOL WITH NORETHISTERONE F Tab 35 µg with norethisterone 1 mg – Up to 63 tab available on a PSO...................................................................................... 6.62 63 Brevinor 1/21 F Tab 35 µg with norethisterone 1 mg and 7 inert tab – Up to 84 tab available on a PSO............................................................ 6.62 84 Brevinor 1/28 F Tab 35 µg with norethisterone 500 µg – Up to 63 tab available on a PSO...................................................................................... 6.62 63 Brevinor 21 F Tab 35 µg with norethisterone 500 µg and 7 inert tab – Up to 84 tab available on a PSO............................................................ 6.62 84 Norimin NORETHISTERONE WITH MESTRANOL F Tab 1 mg with mestranol 50 µg and 7 inert tab ..................................6.62 84 (13.80) Norinyl-1/28 a) Higher subsidy of $13.80 per 84 tab with Special Authority see SA0500 on the preceding page b) Up to 84 tab available on a PSO

Combined Oral Contraceptives - Other

ETHINYLOESTRADIOL WITH LEVONORGESTREL F Tab 20 µg with levonorgestrel 100 µg and 7 inert tab – Up to 84 tab available on a PSO............................................................ 6.62 (16.50) (16.50)

84 Loette Microgynon 20 ED

Progestogen-only Contraceptives

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

GENITO-URINARY SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . Notes: The approval numbers of Special Authorities approved after 1 November 1999 are interchangeable between Mercilon and Marvelon. The additional subsidy will fund Mercilon and Marvelon up to the manufacturer’s price for each of these products as identiﬁed on the Schedule at 1 November 1999. Special Authorities approved before 1 November 1999 remain valid until the expiry date and can be renewed providing that women are still either: G on a Social Welfare beneﬁt; or G have an income no greater than the beneﬁt. The approval numbers of Special Authorities approved before 1 November 1999 are interchangeable for products within the combined oral contraceptives and progestogen-only contraceptives groups, except Loette and Microgynon 20 ED LEVONORGESTREL F Tab 30 µg ............................................................................................6.62 84 (16.50) Microlut a) Higher subsidy of $13.80 per 84 tab with Special Authority see SA0500 on the preceding page b) Up to 84 tab available on a PSO F Subdermal implant (2 × 75 mg rods) .............................................133.65 1 Jadelle MEDROXYPROGESTERONE ACETATE F Inj 150 mg per ml, 1 ml syringe – Up to 5 inj available on a PSO .........7.15 NORETHISTERONE F Tab 350 µg – Up to 84 tab available on a PSO...................................7.15 1 84

Depo-Provera Noriday 28

Emergency Contraceptives

LEVONORGESTREL F Tab 1.5 mg ........................................................................................12.50 a) Up to 5 tab available on a PSO b) Maximum of 2 tab per prescription 1

Postinor-1

Antiandrogen Oral Contraceptives

Prescribers may code prescriptions “contraceptive” (code “O”) when used as indicated for contraception. The period of supply and prescription charge will be as per other contraceptives, as follows: G $3.00 prescription charge (patient co-payment) will apply. G prescription may be written for up to six months supply. Prescriptions coded in any other way are subject to the non contraceptive prescription charges, and the non-contraceptive period of supply. ie. Prescriptions may be written for up to three months supply. CYPROTERONE ACETATE WITH ETHINYLOESTRADIOL F Tab 2 mg with ethinyloestradiol 35 µg and 7 inert tabs ......................3.89 84 Ginet 84

Gynaecological Anti-infectives

ACETIC ACID WITH HYDROXYQUINOLINE AND RICINOLEIC ACID Jelly with glacial acetic acid 0.94%, hydroxyquinoline sulphate 0.025%, glycerol 5% and ricinoleic acid 0.75% with applicator .....................................................................................8.43 (24.00) CLOTRIMAZOLE F Vaginal crm 1% with applicators .........................................................1.30 F Vaginal crm 2% with applicators .........................................................2.50

100 g OP Aci-Jel 35 g OP 20 g OP

Clomazol Clomazol

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

GENITO-URINARY SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

MICONAZOLE NITRATE F Vaginal crm 2% with applicator ..........................................................2.75 (3.70) NYSTATIN Vaginal crm 100,000 u per 5 g with applicator(s) ...............................4.71

40 g OP Micreme 75 g OP

Nilstat

Myometrial and Vaginal Hormone Preparations

ERGOMETRINE MALEATE Inj 500 µg per ml, 1 ml – Up to 5 inj available on a PSO ..................31.00 OESTRIOL F Crm 1 mg per g with applicator ..........................................................6.30 F Pessaries 500 µg ................................................................................6.53 OXYTOCIN – Up to 5 inj available on a PSO Inj 5 iu per ml, 1 ml .............................................................................5.94 Inj 10 iu per ml, 1 ml ...........................................................................7.48 Inj 5 iu with ergometrine maleate 500 µg per ml, 1 ml ......................10.12 5 15 g OP 15 5 5 5

DBL Ergometrine Ovestin Ovestin Syntocinon Syntocinon Syntometrine

Pregnancy Tests - hCG Urine

PREGNANCY TESTS - HCG URINE a) Up to 200 test available on a PSO b) Only on a PSO Cassette ...........................................................................................22.80

40 test OP

Innovacon hCG One

Step Pregnancy Test

Urinary Agents

For urinary tract Infections refer to INFECTIONS, Antibacterials, page 93

5-Alpha Reductase Inhibitors

FINASTERIDE – Special Authority see SA0928 below – Retail pharmacy Tab 5 mg ............................................................................................5.10 (Fintral Tab 5 mg to be delisted 1 February 2012) ¾SA0928 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Both: 1 Patient has symptomatic benign prostatic hyperplasia; and 2 Either: 2.1 The patient is intolerant of non-selective alpha blockers or these are contraindicated; or 2.2 Symptoms are not adequately controlled with non-selective alpha blockers. Note: Patients with enlarged prostates are the appropriate candidates for therapy with ﬁnasteride. 30

Fintral Rex Medical

Alpha-1A Adrenoreceptor Blockers

TAMSULOSIN HYDROCHLORIDE – Special Authority see SA1032 on the next page – Retail pharmacy Cap 400 µg .........................................................................................5.98 30 Tamsulosin-Rex

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

GENITO-URINARY SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA1032 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Both: 1 Patient has symptomatic benign prostatic hyperplasia; and 2 The patient is intolerant of non-selective alpha blockers or these are contraindicated.

Other Urinary Agents

OXYBUTYNIN F Tab 5 mg ...........................................................................................44.79 F Oral liq 5 mg per 5 ml .......................................................................50.40 POTASSIUM CITRATE Oral liq 3 mmol per ml – Special Authority see SA1083 below – Retail pharmacy ..................................................................... 30.00 500 473 ml OP

Apo-Oxybutynin Apo-Oxybutynin

200 ml OP

Biomed

¾SA1083 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 The patient has recurrent calcium oxalate urolithiasis; and 2 The patient has had more than two renal calculi in the two years prior to the application. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁtting from the treatment. SODIUM CITRO-TARTRATE F Grans eff 4 g sachets .........................................................................2.71 28 Ural SOLIFENACIN SUCCINATE – Special Authority see SA0998 below – Retail pharmacy Tab 5 mg ...........................................................................................56.50 30 Tab 10 mg .........................................................................................56.50 30

Vesicare Vesicare

¾SA0998 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid without further renewal unless notiﬁed where the patient has overactive bladder and a documented intolerance of oxybutynin.

Detection of Substances in Urine

ORTHO-TOLIDINE F Compound diagnostic sticks ...............................................................7.50 (8.25) TETRABROMOPHENOL F Blue diagnostic strips .........................................................................7.02 (13.92) 50 test OP Hemastix 100 test OP Albustix

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

HORMONE PREPARATIONS - SYSTEMIC EXCLUDING CONTRACEPTIVE HORMONES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Anabolic Agents

NANDROLONE DECANOATE – Retail pharmacy-Specialist Inj 50 mg per ml, 1 ml .......................................................................21.16 1

Deca-Durabolin

Orgaject S29

Corticosteroids and Related Agents for Systemic Use

BETAMETHASONE SODIUM PHOSPHATE WITH BETAMETHASONE ACETATE F Inj 3.9 mg with betamethasone acetate 3 mg per ml, 1 ml ...............19.20 (33.60) 5 Celestone Chronodose

DEXAMETHASONE F Tab 1 mg – Retail pharmacy-Specialist ............................................16.08 100 Up to 30 tab available on a PSO F Tab 4 mg – Retail pharmacy-Specialist ............................................61.89 100 Up to 30 tab available on a PSO Oral liq 1 mg per ml – Retail pharmacy-Specialist ...........................39.90 25 ml OP Oral liq prescriptions: 1) Must be written by a Paediatrician or Paediatric Cardiologist; or 2) On the recommendation of a Paediatrician or Paediatric Cardiologist. DEXAMETHASONE SODIUM PHOSPHATE Dexamethasone sodium phosphate injection will not be funded for oral use. F Inj 4 mg per ml, 1 ml – Up to 5 inj available on a PSO .....................21.50 5 F Inj 4 mg per ml, 2 ml – Up to 5 inj available on a PSO .....................31.00 5 FLUDROCORTISONE ACETATE F Tab 100 µg ........................................................................................14.32 HYDROCORTISONE F Tab 5 mg .............................................................................................8.35 F Tab 20 mg – For hydrocortisone oral liquid formulation refer, page 172 ....................................................................................20.95 F Inj 50 mg per ml, 2 ml .........................................................................3.99 a) Up to 5 inj available on a PSO b) Only on a PSO METHYLPREDNISOLONE – Retail pharmacy-Specialist F Tab 4 mg ...........................................................................................48.57 F Tab 100 mg .....................................................................................166.52 METHYLPREDNISOLONE ACETATE Inj 40 mg per ml, 1 ml .........................................................................6.03 METHYLPREDNISOLONE ACETATE WITH LIGNOCAINE Inj 40 mg per ml with lignocaine 1 ml .................................................6.03 METHYLPREDNISOLONE SODIUM SUCCINATE – Retail pharmacy-Specialist Inj 40 mg per ml, 1 ml .........................................................................6.06 151.40 Inj 62.5 mg per ml, 2 ml ....................................................................16.50 412.59 Inj 500 mg .........................................................................................20.80 Inj 1 g ................................................................................................42.57 100 100 100 1

Douglas Douglas Biomed

Hospira Hospira Florinef Douglas Douglas Solu-Cortef

100 20 1 1

Medrol Medrol Depo-Medrol Depo-Medrol with

Lidocaine

1 25 1 25 1 1

Solu-Medrol Solu-Medrol Solu-Medrol Solu-Medrol Solu-Medrol Solu-Medrol

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

HORMONE PREPARATIONS - SYSTEMIC EXCLUDING CONTRACEPTIVE HORMONES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

PREDNISOLONE SODIUM PHOSPHATE F Oral liq 5 mg per ml – Up to 30 ml available on a PSO ......................9.95 Restricted to children under 12 years of age. PREDNISONE F Tab 1 mg ...........................................................................................10.68 F Tab 2.5 mg ........................................................................................12.09 F Tab 5 mg – Up to 30 tab available on a PSO....................................11.09 F Tab 20 mg .........................................................................................29.03 TETRACOSACTRIN F Inj 250 µg ........................................................................................177.18 F Inj 1 mg per ml, 1 ml .........................................................................29.56 TRIAMCINOLONE ACETONIDE Inj 10 mg per ml, 1 ml .......................................................................11.11 Inj 40 mg per ml, 1 ml .......................................................................28.09

30 ml OP

Redipred

500 500 500 500 10 1 5 5

Apo-Prednisone Apo-Prednisone Apo-Prednisone Apo-Prednisone Synacthen Synacthen Depot Kenacort-A Kenacort-A40

Sex Hormones Non Contraceptive Androgen Agonists and Antagonists

CYPROTERONE ACETATE – Retail pharmacy-Specialist Tab 50 mg .........................................................................................21.10 Tab 100 mg .......................................................................................41.50 TESTOSTERONE Transdermal patch, 2.5 mg per day ..................................................80.00 TESTOSTERONE CYPIONATE – Retail pharmacy-Specialist Inj long-acting 100 mg per ml, 10 ml ................................................76.50 TESTOSTERONE ESTERS – Retail pharmacy-Specialist Inj 250 mg per ml, 1 ml .....................................................................12.98 TESTOSTERONE UNDECANOATE – Retail pharmacy-Specialist Cap 40 mg ........................................................................................79.92 50 50 60 1 1 100

Siterone Siterone Androderm Depo-Testosterone Sustanon Ampoules Arrow-Testosterone

Hormone Replacement Therapy - Systemic

¾SA1018 Special Authority for Alternate Subsidy Initial application from any relevant practitioner. Approvals valid for 5 years for applications meeting the following criteria: Any of the following: 1 acute or signiﬁcant liver disease - where oral oestrogens are contraindicated as determined by a gastroenterologist or general physician. The applicant must keep written conﬁrmation from such a specialist with the patient’s record; or 2 oestrogen induced hypertension requiring antihypertensive therapy - documented evidence must be kept on ﬁle that raised blood pressure levels or inability to control blood pressure adequately occurred post oral oestrogens; or 3 hypertriglyceridaemia - documented evidence must be kept on ﬁle that triglyceride levels increased to at least 2 × normal triglyceride levels post oral oestrogens; or 4 Somatropin co-therapy - patient is being prescribed somatropin with subsidy provided under a valid approval issued under Special Authority. Note: Prescriptions with a valid Special Authority (CHEM) number will be reimbursed at the level of the lowest priced TDDS product within the speciﬁed dose group. Renewal from any relevant practitioner. Approvals valid for 5 years where the treatment remains appropriate and the patient is beneﬁting from treatment, or the patient remains on subsidised somatropin co-therapy.

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

HORMONE PREPARATIONS - SYSTEMIC EXCLUDING CONTRACEPTIVE HORMONES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Prescribing Guideline HRT should be taken at the lowest dose for the shortest period of time necessary to control symptoms. Patients should be reviewed 6 monthly in line with the updated NZGG “Evidence-based Best Practice Guideline on Hormone Replacement Therapy March 2004”.

Oestrogens

OESTRADIOL – See prescribing guideline below F Tab 1 mg .............................................................................................4.12 28 OP (10.55) Estrofem F Tab 2 mg .............................................................................................4.12 28 OP (10.55) Estrofem F TDDS 25 µg per day .........................................................................3.01 8 (10.86) Estraderm TTS 25 (10.86) Estradot a) Higher subsidy of $10.86 per 8 patch with Special Authority see SA1018 on the preceding page b) No more than 2 patch per week c) Only on a prescription F TDDS 3.9 mg (releases 50 µg of oestradiol per day) ........................4.12 4 (13.18) Climara 50 (32.50) Femtran 50 a) Higher subsidy of $13.18 per 4 patch with Special Authority see SA1018 on the preceding page b) No more than 1 patch per week c) Only on a prescription F TDDS 50 µg per day .........................................................................4.12 8 (13.18) Estraderm TTS 50 (13.18) Estradot 50 µg a) Higher subsidy of $13.18 per 8 patch with Special Authority see SA1018 on the preceding page b) No more than 2 patch per week c) Only on a prescription F TDDS 7.8 mg (releases 100 µg of oestradiol per day) ......................7.05 4 (16.14) Climara 100 (35.00) Femtran 100 a) Higher subsidy of $16.14 per 4 patch with Special Authority see SA1018 on the preceding page b) No more than 1 patch per week c) Only on a prescription F TDDS 100 µg per day .......................................................................7.05 8 (16.14) Estraderm TTS 100 (16.14) Estradot a) Higher subsidy of $16.14 per 8 patch with Special Authority see SA1018 on the preceding page b) No more than 2 patch per week c) Only on a prescription (Estraderm TTS 25 TDDS 25 µg per day to be delisted 1 January 2012) (Estraderm TTS 50 TDDS 50 µg per day to be delisted 1 January 2012) (Estraderm TTS 100 TDDS 100 µg per day to be delisted 1 January 2012) OESTRADIOL VALERATE – See prescribing guideline below F Tab 1 mg .............................................................................................8.24 F Tab 2 mg .............................................................................................8.24 56 56

Progynova Progynova

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

HORMONE PREPARATIONS - SYSTEMIC EXCLUDING CONTRACEPTIVE HORMONES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

OESTROGENS – See prescribing guideline on the preceding page F Conjugated, equine tab 300 µg ..........................................................3.01 (11.48) F Conjugated, equine tab 625 µg ..........................................................4.12 (11.48)

28 Premarin 28 Premarin

Progestogens

MEDROXYPROGESTERONE ACETATE – See prescribing guideline on the preceding page F Tab 2.5 mg ..........................................................................................3.09 30 F Tab 5 mg ...........................................................................................13.06 100 F Tab 10 mg ...........................................................................................6.85 30

Provera Provera Provera

Progestogen and Oestrogen Combined Preparations

OESTRADIOL WITH NORETHISTERONE – See prescribing guideline on the preceding page F Tab 1 mg with 0.5 mg norethisterone acetate .....................................5.40 28 OP (14.52) F Tab 2 mg with 1 mg norethisterone acetate ........................................5.40 28 OP (14.52) F Tab 2 mg with 1 mg norethisterone acetate (10), and 2 mg oestradiol tab (12) and 1 mg oestradiol tab (6) ............................5.40 28 OP (14.52)

Kliovance Kliogest

Trisequens

OESTROGENS WITH MEDROXYPROGESTERONE – See prescribing guideline on the preceding page F Tab 625 µg conjugated equine with 2.5 mg medroxyprogesterone acetate tab (28) ................................................................5.40 28 OP (22.96) Premia 2.5 Continuous F Tab 625 µg conjugated equine with 5 mg medroxyprogesterone acetate tab (28) ................................................................5.40 28 OP (22.96) Premia 5 Continuous

Other Oestrogen Preparations

ETHINYLOESTRADIOL F Tab 10 µg ..........................................................................................17.60 OESTRIOL F Tab 2 mg .............................................................................................7.00 100

NZ Medical and

Scientiﬁc

Ovestin

Other Progestogen Preparations

LEVONORGESTREL F Levonorgestrel - releasing intrauterine system 20 µg/24 hr – Special Authority see SA0782 on the next page – Retail pharmacy ................................................................................. 269.50

Mirena

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

HORMONE PREPARATIONS - SYSTEMIC EXCLUDING CONTRACEPTIVE HORMONES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA0782 Special Authority for Subsidy Initial application — (No previous use) only from a relevant specialist or general practitioner. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 The patient has a clinical diagnosis of heavy menstrual bleeding; and 2 The patient has failed to respond to or is unable to tolerate other appropriate pharmaceutical therapies as per the Heavy Menstrual Bleeding Guidelines; and 3 Either: 3.1 serum ferritin level < 16 µg/l (within the last 12 months); or 3.2 haemoglobin level < 120 g/l. Note: Applications are not to be made for use in patients as contraception except where they meet the above criteria. Initial application — (Previous use before 1 October 2002) only from a relevant specialist or general practitioner. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 The patient had a clinical diagnosis of heavy menstrual bleeding; and 2 Patient demonstrated clinical improvement of heavy menstrual bleeding; and 3 Applicant to state date of the previous insertion. Note: Applications are not to be made for use in patients as contraception except where they meet the above criteria. Renewal only from a relevant specialist or general practitioner. Approvals valid for 6 months for applications meeting the following criteria: Both: 1 Either: 1.1 Patient demonstrated clinical improvement of heavy menstrual bleeding; or 1.2 Previous insertion was removed or expelled within 3 months of insertion; and 2 Applicant to state date of the previous insertion. MEDROXYPROGESTERONE ACETATE F Tab 100 mg – Retail pharmacy-Specialist ........................................96.50 100 Provera F Tab 200 mg – Retail pharmacy-Specialist ........................................70.50 30 Provera NORETHISTERONE F Tab 5 mg – Up to 30 tab available on a PSO....................................26.50 100

Primolut N

Thyroid and Antithyroid Agents

CARBIMAZOLE F Tab 5 mg ...........................................................................................10.80 LEVOTHYROXINE F Tab 25 µg ............................................................................................3.89 43.24 ‡ Safety cap for extemporaneously compounded oral liquid preparations. F Tab 50 µg ............................................................................................1.71 4.05 45.00 64.28 ‡ Safety cap for extemporaneously compounded oral liquid preparations. F Tab 100 µg ..........................................................................................1.78 4.21 66.78 ‡ Safety cap for extemporaneously compounded oral liquid preparations. 100 90 1,000 28 90 1,000

Neo-Mercazole Synthroid Synthroid Goldshield Synthroid Synthroid Eltroxin Goldshield Synthroid Eltroxin

28 90 1,000

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

HORMONE PREPARATIONS - SYSTEMIC EXCLUDING CONTRACEPTIVE HORMONES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Trophic Hormones Growth Hormones

¾SA0755 Special Authority for Subsidy Special Authority approved by the Growth Hormone Committee Notes: Subject to budgetary cap. Applications will be considered and approved subject to funding availability. Application details may be obtained from PHARMAC’s website http://www.pharmac.govt.nz or: NZGHC Coordinator PHARMAC, PO Box 10-254, WELLINGTON Tel: 0800 808 476, Fax: (09) 929 3221, Email: growthhormone@pharmac.govt.nz SOMATROPIN – Special Authority see SA0755 above F Inj cartridge 16 iu (5.3 mg) .............................................................160.00 F Inj cartridge 36 iu (12 mg) ..............................................................360.00 1 1

Genotropin Genotropin

GnRH Analogues

GOSERELIN ACETATE Inj 3.6 mg ........................................................................................166.20 Inj 10.8 mg ......................................................................................443.76 LEUPRORELIN Inj 3.75 mg ......................................................................................221.60 Inj 3.75 mg preﬁlled syringe ...........................................................221.60 Inj 7.5 mg ........................................................................................166.20 Inj 11.25 mg ....................................................................................591.68 Inj 11.25 mg preﬁlled syringe .........................................................591.68 Inj 22.5 mg ......................................................................................443.76 Inj 30 mg .........................................................................................591.68 Inj 30 mg preﬁlled syringe ...........................................................1,109.40 Inj 45 mg .........................................................................................832.05 1 1 1 1 1 1 1 1 1 1 1

Zoladex Zoladex Lucrin Depot Lucrin Depot PDS Eligard Lucrin Depot Lucrin Depot PDS Eligard Eligard Lucrin Depot PDS Eligard

Vasopressin Agonists

DESMOPRESSIN L Nasal drops 100 µg per ml – Retail pharmacy-Specialist.................39.03 L Nasal spray 10 µg per dose – Retail pharmacy-Specialist ...............27.48 Inj 4 µg per ml, 1 ml – Special Authority see SA0090 below – Retail pharmacy ........................................................................ 67.18 2.5 ml OP 6 ml OP

Minirin DesmopressinPH&T

Minirin

¾SA0090 Special Authority for Subsidy Initial application only from a relevant specialist. Approvals valid for 2 years where the patient cannot use desmopressin nasal spray or nasal drops. Renewal only from a relevant specialist. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment.

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

HORMONE PREPARATIONS - SYSTEMIC EXCLUDING CONTRACEPTIVE HORMONES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Other Endocrine Agents

CABERGOLINE Tab 0.5 mg – Maximum of 2 tab per prescription; can be waived by Special Authority see SA1031 below.........................16.50 66.00 16.50 66.00

2 8 2 8

Dostinex Dostinex Arrow-Cabergoline Arrow-Cabergoline

¾SA1031 Special Authority for Waiver of Rule Initial application only from an obstetrician, endocrinologist or gynaecologist. Approvals valid without further renewal unless notiﬁed where the patient has pathological hyperprolactinemia. Renewal only from an obstetrician, endocrinologist or gynaecologist. Approvals valid without further renewal unless notiﬁed where the patient has previously held a valid Special Authority which has expired and the treatment remains appropriate and the patient is beneﬁting from treatment. CLOMIPHENE CITRATE 10 Serophene Tab 50 mg .........................................................................................29.84 DANAZOL – Retail pharmacy-Specialist Cap 100 mg ......................................................................................68.33 Cap 200 mg ......................................................................................97.83 GESTRINONE – Retail pharmacy-Specialist Cap 2.5 mg .....................................................................................101.87 METYRAPONE Cap 250 mg – Retail pharmacy-Specialist .....................................238.00 100 100 8 OP 50

Azol Azol Dimetriose Metopirone

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Anthelmintics

MEBENDAZOLE – Only on a prescription Tab 100 mg .......................................................................................24.19 Oral liq 100 mg per 5 ml .....................................................................2.18 (7.17) 24 15 ml

De-Worm

Vermox

Antibacterials

a) For topical antibacterials, refer to DERMATOLOGICALS, page 57 b) For anti-infective eye preparations, refer to SENSORY ORGANS, page 166

Cephalosporins and Cephamycins

CEFACLOR MONOHYDRATE Cap 250 mg ......................................................................................24.57 28.90 Grans for oral liq 125 mg per 5 ml ......................................................3.53 100 100 ml

Cefaclor Sandoz Ranbaxy-Cefaclor Ranbaxy-Cefaclor

CEFAZOLIN SODIUM – Subsidy by endorsement Only if prescribed for dialysis or cystic ﬁbrosis patient and the prescription is endorsed accordingly. Inj 500 mg ...........................................................................................5.00 5 Hospira Inj 1 g ..................................................................................................8.00 5 Hospira CEFOXITIN SODIUM – Retail pharmacy-Specialist – Subsidy by endorsement Only if prescribed for dialysis or cystic ﬁbrosis patient and the prescription is endorsed accordingly. Inj 1 g ................................................................................................55.00 5 Mayne CEFTRIAXONE SODIUM – Subsidy by endorsement a) Up to 5 inj available on a PSO b) Subsidised only if prescribed for a dialysis or cystic ﬁbrosis patient, or the treatment of conﬁrmed ciproﬂoxacin-resistant gonorrhoea, or the treatment of suspected meningitis in patients who have a known allergy to penicillin, and the prescription or PSO is endorsed accordingly. Inj 500 mg ...........................................................................................2.70 1 Veracol Inj 1 g ................................................................................................10.49 5 Aspen Ceftriaxone CEFUROXIME AXETIL – Subsidy by endorsement Only if prescribed for prophylaxis of endocarditis and the prescription is endorsed accordingly. Tab 250 mg .......................................................................................29.40 50 Zinnat CEFUROXIME SODIUM Inj 250 mg – Maximum of 3 inj per prescription; can be waived by endorsement.......................................................................... 20.97 10 Mayne Inj 750 mg – Maximum of 1 inj per prescription; can be waived by endorsement.......................................................................... 10.71 5 Zinacef Inj 1.5 g – Retail pharmacy-Specialist – Subsidy by endorsement..............................................................................................4.04 1 Zinacef Only if prescribed for dialysis or cystic ﬁbrosis patient and the prescription is endorsed accordingly. CEPHALEXIN MONOHYDRATE Cap 500 mg ........................................................................................8.90 20 Cephalexin ABM Grans for oral liq 125 mg per 5 ml ......................................................8.50 100 ml Cefalexin Sandoz Grans for oral liq 250 mg per 5 ml ....................................................11.50 100 ml Cefalexin Sandoz

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Macrolides

AZITHROMYCIN – Subsidy by endorsement; can be waived by Special Authority see SA1130 below a) Maximum of 2 tab per prescription; can be waived by Special Authority see SA1130 below b) Up to 8 tab available on a PSO c) Subsidised only if prescribed for patients with uncomplicated urethritis or cervicitis proven or presumed to be due to chlamydia trachomatis and their sexual contacts and prescription or PSO is endorsed accordingly; can be waived by Special Authority see SA1130. Tab 500 mg .........................................................................................5.95 2 OP Arrow-Azithromycin ¾SA1130 Special Authority for Waiver of Rule Initial application — (Cystic Fibrosis) only from a respiratory specialist or paediatrician. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: All of the following: 1 The applicant is part of multidisciplinary team experienced in the management of cystic ﬁbrosis; and 2 The patient has been deﬁnitively diagnosed with cystic ﬁbrosis*; and 3 The patient has chronic infection with Pseudomonas aeruginosa or Pseudomonas related gram negative organisms as deﬁned by two positive respiratory tract cultures at least three months apart*; and 4 The patient has negative cultures for non-tuberculous mycobacteria. Notes: Caution is advised if using azithromycin as an antibiotic in the treatment of cystic ﬁbrosis patients with pneumonia. Testing for non-tuberculosis mycobacteria should occur annually. Initial application — (bronchiolitis obliterans syndrome) only from a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: All of the following: 1 Patient has received a lung transplant; and 2 Azithromycin is to be used for prophylaxis of bronchiolitis obliterans syndrome*; and 3 The applicant is experienced in managing patients who have received a lung transplant. Renewal — (bronchiolitis obliterans syndrome) only from a relevant specialist. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Both: 1 The patient remains well and free from bronchiolits obliterans syndrome*; and 2 The applicant is experienced in managing patients who have received a lung transplant. Note: Indications marked with * are Unapproved Indications CLARITHROMYCIN – Maximum of 500 mg per prescription; can be waived by Special Authority see SA1131 below Tab 250 mg .........................................................................................4.19 14 Apo-Clarithromycin 7.75 Klacid Klamycin Grans for oral liq 125 mg per 5 ml ....................................................23.12 70 ml Klacid ¾SA1131 Special Authority for Waiver of Rule Initial application — (Mycobacterial infections) only from a respiratory specialist, infectious disease specialist or paediatrician. Approvals valid for 2 years for applications meeting the following criteria: Either: 1 Atypical mycobacterial infection; or 2 Mycobacterium tuberculosis infection where there is drug-resistance or intolerance to standard pharmaceutical agents. Renewal — (Mycobacterial infections) only from a respiratory specialist, infectious disease specialist or paediatrician. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment.

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

ERYTHROMYCIN ETHYL SUCCINATE Tab 400 mg – Up to 30 tab available on a PSO................................16.95 Grans for oral liq 200 mg per 5 ml – Up to 200 ml available on a PSO......................................................................................4.35 Grans for oral liq 400 mg per 5 ml – Up to 200 ml available on a PSO......................................................................................5.85 ERYTHROMYCIN LACTOBIONATE Inj 1 g ................................................................................................10.93 ERYTHROMYCIN STEARATE Tab 250 mg – Up to 30 tab available on a PSO................................14.95 (22.29) Tab 500 mg .......................................................................................29.90 (44.58) ROXITHROMYCIN Tab 150 mg .........................................................................................8.98 Tab 300 mg .......................................................................................16.48

100 100 ml 100 ml 1 100

E-Mycin E-Mycin E-Mycin Erythrocin IV

ERA 100 ERA 50 50

ArrowRoxithromycin

Penicillins

AMOXYCILLIN Cap 250 mg – Up to 30 cap available on a PSO..............................16.18 Cap 500 mg ......................................................................................26.50 Grans for oral liq 125 mg per 5 ml – Up to 200 ml available on a PSO......................................................................................1.55 Grans for oral liq 250 mg per 5 ml – Up to 200 ml available on a PSO......................................................................................1.10 Drops 125 mg per 1.25 ml ..................................................................4.00 Inj 250 mg .........................................................................................12.96 Inj 500 mg .........................................................................................15.08 Inj 1 g – Up to 5 inj available on a PSO............................................21.94 AMOXYCILLIN CLAVULANATE Tab amoxycillin 500 mg with potassium clavulanate 125 mg – Up to 30 tab available on a PSO ............................................. 26.00 Grans for oral liq amoxycillin 125 mg with potassium clavulanate 31.25 mg per 5 ml – Up to 200 ml available on a PSO..............................................................................................2.20 Grans for oral liq amoxycillin 250 mg with potassium clavulanate 62.5 mg per 5 ml – Up to 200 ml available on a PSO..............................................................................................3.85 BENZATHINE BENZYLPENICILLIN Inj 1.2 mega u per 2.3 ml – Up to 5 inj available on a PSO............315.00 BENZYLPENICILLIN SODIUM (PENICILLIN G) Inj 600 mg – Up to 5 inj available on a PSO.....................................11.50 500 500 100 ml 100 ml 30 ml OP 10 10 10

Alphamox Alphamox Ospamox Ospamox Ospamox Paediatric

Drops

Ibiamox Ibiamox Ibiamox

100

Synermox Curam Curam Bicillin LA Sandoz

100 ml

100 ml 10 10

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

FLUCLOXACILLIN SODIUM Cap 250 mg – Up to 30 cap available on a PSO..............................32.00 Cap 500 mg ....................................................................................110.00 Grans for oral liq 125 mg per 5 ml – Up to 200 ml available on a PSO...................................................................................... 3.12 Grans for oral liq 250 mg per 5 ml – Up to 200 ml available on a PSO...................................................................................... 3.55 Inj 250 mg .........................................................................................10.86 Inj 500 mg .........................................................................................11.32 Inj 1 g – Up to 5 inj available on a PSO............................................14.28 PHENOXYMETHYLPENICILLIN (PENICILLIN V) Cap potassium salt 250 mg – Up to 30 cap available on a PSO .........9.71 Cap potassium salt 500 mg ..............................................................11.70 Grans for oral liq 125 mg per 5 ml – Up to 200 ml available on a PSO...................................................................................... 1.68 Grans for oral liq 250 mg per 5 ml – Up to 200 ml available on a PSO...................................................................................... 1.78 PROCAINE PENICILLIN Inj 1.5 mega u – Up to 5 inj available on a PSO.............................123.50

250 500 100 ml 100 ml 10 10 10 50 50 100 ml 100 ml 5

AFT AFT AFT AFT Flucloxin Flucloxin Flucloxin Cilicaine VK Cilicaine VK AFT AFT Cilicaine

Tetracyclines

DOXYCYCLINE HYDROCHLORIDE F Tab 50 mg – Up to 30 tab available on a PSO....................................2.90 (6.00) F Tab 100 mg – Up to 30 tab available on a PSO..................................7.95 MINOCYCLINE HYDROCHLORIDE F Tab 50 mg ...........................................................................................5.79 (12.05) F Cap 100 mg ......................................................................................19.32 (52.04) 30 Doxy-50 250 60 Mino-tabs 100 Minomycin

Doxine

Other Antibiotics

For topical antibiotics, refer to DERMATOLOGICALS, page 57 CIPROFLOXACIN Tab 250 mg – Up to 5 tab available on a PSO....................................2.20 2.36 (3.35) Tab 500 mg – Up to 5 tab available on a PSO....................................3.00 3.21 (4.90) Tab 750 mg – Retail pharmacy-Specialist ..........................................5.15 5.52 (7.54) (Rex Medical Tab 250 mg to be delisted 1 March 2012) (Rex Medical Tab 500 mg to be delisted 1 March 2012) (Rex Medical Tab 750 mg to be delisted 1 March 2012)

28 30 28 30 28 30

Cipﬂox

Rex Medical

Cipﬂox

Rex Medical

Cipﬂox

Rex Medical

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

CLINDAMYCIN Cap hydrochloride 150 mg – Maximum of 4 cap per prescription; can be waived by endorsement - Retail pharmacy Specialist .................................................................................... 11.39 Inj phosphate 150 mg per ml, 4 ml – Retail pharmacySpecialist .................................................................................. 160.00 CO-TRIMOXAZOLE F Tab trimethoprim 80 mg and sulphamethoxazole 400 mg – Up to 30 tab available on a PSO ................................................ 20.97 F Oral liq trimethoprim 40 mg and sulphamethoxazole 200 mg per 5 ml – Up to 200 ml available on a PSO................................2.15

16 10

Dalacin C Dalacin C

500 100 ml

Trisul Deprim

COLISTIN SULPHOMETHATE – Retail pharmacy-Specialist – Subsidy by endorsement Only if prescribed for dialysis or cystic ﬁbrosis patient and the prescription is endorsed accordingly. Inj 150 mg .........................................................................................65.00 1 Colistin-Link FUSIDIC ACID Tab 250 mg – Retail pharmacy-Specialist ........................................34.50 12 Fucidin Inj 500 mg sodium fusidate per 10 ml – Retail pharmacySpecialist – Subsidy by endorsement......................................... 12.87 1 (17.80) Fucidin Only if prescribed for a dialysis or cystic ﬁbrosis patient and the prescription is endorsed accordingly. GENTAMICIN SULPHATE Inj 10 mg per ml, 1 ml – Subsidy by endorsement ..............................8.56 5 Mayne Only if prescribed for a dialysis or cystic ﬁbrosis patient or for prophylaxis of endocarditis and the prescription is endorsed accordingly. Inj 40 mg per ml, 2 ml – Subsidy by endorsement ..............................9.00 10 Pﬁzer Only if prescribed for a dialysis or cystic ﬁbrosis patient or for prophylaxis of endocarditis and the prescription is endorsed accordingly. LINCOMYCIN – Retail pharmacy-Specialist Inj 300 mg per ml, 2 ml .....................................................................80.00 5 Lincocin MOXIFLOXACIN – Special Authority see SA1065 below – Retail pharmacy No patient co-payment payable Tab 400 mg .......................................................................................52.00

Avelox

¾SA1065 Special Authority for Subsidy Initial application only from a respiratory specialist or infectious disease specialist. Approvals valid for 1 year for applications meeting the following criteria: Either: 1 Both: 1.1 Active tuberculosis*; and 1.2 Any of the following: 1.2.1 Documented resistance to one or more ﬁrst-line medications; or 1.2.2 Suspected resistance to one or more ﬁrst-line medications (tuberculosis assumed to be contracted in an area with known resistance), as part of regimen containing other second-line agents; or 1.2.3 Impaired visual acuity (considered to preclude ethambutol use); or 1.2.4 Signiﬁcant pre-existing liver disease or hepatotoxicity from tuberculosis medications; or 1.2.5 Signiﬁcant documented intolerance and/or side effects following a reasonable trial of ﬁrst-line medications; or 2 Mycobacterium avium-intracellulare complex not responding to other therapy or where such therapy is contraindicated.*. continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . Note: Indications marked with * are Unapproved Indications (refer to Section A: General Rules, Part I (Interpretations and Deﬁnitions) and Part IV (Miscellaneous Provisions) rule 4.6). Renewal only from a respiratory specialist or infectious disease specialist. Approvals valid for 1 year where the treatment remains appropriate and the patient is beneﬁting from treatment. TOBRAMYCIN Inj 40 mg per ml, 2 ml – Subsidy by endorsement ............................29.32 5 DBL Tobramycin Only if prescribed for dialysis or cystic ﬁbrosis patient and the prescription is endorsed accordingly. TRIMETHOPRIM F Tab 300 mg – Up to 30 tab available on a PSO..................................8.69 50 TMP VANCOMYCIN HYDROCHLORIDE – Subsidy by endorsement Only if prescribed for a dialysis or cystic ﬁbrosis patient or in the treatment of pseudomembranous colitis or for prophylaxis of endocarditis and the prescription is endorsed accordingly. Inj 500 mg ...........................................................................................3.58 1 Mylan

Antifungals

a) For topical antifungals refer to DERMATOLOGICALS, page 57 b) For topical antifungals refer to GENITO URINARY, page 69 FLUCONAZOLE Cap 50 mg – Retail pharmacy-Specialist ...........................................4.77 28 Ozole 6.82 Paciﬁc Cap 150 mg – Subsidy by endorsement .............................................0.91 1 Ozole 1.30 Paciﬁc a) Maximum of 1 cap per prescription; can be waived by endorsement - Retail pharmacy - Specialist b) Patient has vaginal candida albicans and the practitioner considers that a topical imidazole (used intr-vaginally) is not recommended and the prescription is endorsed accordingly; can be waived by endorsement - Retail pharmacy - Specialist. Cap 200 mg – Retail pharmacy-Specialist .......................................13.34 28 Ozole 19.05 Paciﬁc Powder for oral suspension 10 mg per ml – Special Authority see SA1148 below – Retail pharmacy ......................................34.56 35 ml Diﬂucan ¾SA1148 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 6 weeks for applications meeting the following criteria: Both: 1 Patient requires prophlaxis for, or treatment of systemic candidiasis; and 2 Patient is unable to swallow capsules. Renewal from any relevant practitioner. Approvals valid for 6 weeks for applications meeting the following criteria: Both: 1 Patient requires prophlaxis for, or treatment of systemic candidiasis; and 2 Patient is unable to swallow capsules. ITRACONAZOLE – Retail pharmacy-Specialist Cap 100 mg ........................................................................................4.25 15 Itrazole KETOCONAZOLE Tab 200 mg – Retail pharmacy-Specialist ........................................38.12 NYSTATIN Tab 500,000 u ...................................................................................14.16 Cap 500,000 u ..................................................................................12.81 30 50 50

Nizoral Nilstat Nilstat

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

TERBINAFINE Tab 250 mg – For terbinaﬁne oral liquid formulation refer, page 172 ......................................................................................1.78 12.75 (25.50) (Apo-Terbinaﬁne Tab 250 mg to be delisted 1 February 2012)

14 100

Dr Reddy’s

Terbinaﬁne Apo-Terbinaﬁne

Antimalarials

HYDROXYCHLOROQUINE SULPHATE F Tab 200 mg .......................................................................................22.50 100

Plaquenil

Antitrichomonal Agents

METRONIDAZOLE Tab 200 mg – Up to 30 tab available on a PSO..................................9.50 Tab 400 mg .......................................................................................17.50 Oral liq benzoate 200 mg per 5 ml ...................................................25.00 Suppos 500 mg ................................................................................24.48 ORNIDAZOLE Tab 500 mg ......................................................................................12.38 16.50 (Tiberal Tab 500 mg to be delisted 1 May 2012) 100 100 100 ml 10 10

Trichozole Trichozole Flagyl-S Flagyl Tiberal Arrow-Ornidazole

Antituberculotics and Antileprotics

Note: There is no co-payment charge for all pharmaceuticals listed in the Antituberculotics and Antileprotics group regardless of immigration status. DAPSONE – No patient co-payment payable Tab 25 mg .........................................................................................95.00 100 Dapsone Tab 100 mg .....................................................................................110.00 100 Dapsone ETHAMBUTOL HYDROCHLORIDE – No patient co-payment payable Tab 100 mg .......................................................................................48.01 Tab 400 mg .......................................................................................49.34 ISONIAZID – Retail pharmacy-Specialist No patient co-payment payable F Tab 100 mg .......................................................................................20.00 F Tab 100 mg with rifampicin 150 mg ..................................................90.04 F Tab 150 mg with rifampicin 300 mg ................................................179.57 PYRAZINAMIDE – Retail pharmacy-Specialist No patient co-payment payable F Tab 500 mg – For pyrazinamide oral liquid formulation refer, page 172 .................................................................................... 59.00 RIFABUTIN – Retail pharmacy-Specialist No patient co-payment payable F Cap 150 mg – For rifabutin oral liquid formulation refer, page 172 ........................................................................................... 213.19 56 56

Myambutol Myambutol

100 100 100

PSM Riﬁnah Riﬁnah

100

AFT-Pyrazinamide

Mycobutin

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

RIFAMPICIN – Retail pharmacy-Specialist No patient co-payment payable F Tab 600 mg .....................................................................................114.40 F Cap 150 mg ......................................................................................58.66 F Cap 300 mg ....................................................................................122.36 F Oral liq 100 mg per 5 ml ...................................................................12.66

30 100 100 60 ml

Rifadin Rifadin Rifadin Rifadin

Antivirals

For eye preparations refer to Eye Preparations, Anti-Infective Preparations, page 166

Hepatitis B Treatment

ADEFOVIR DIPIVOXIL – Special Authority see SA0829 below – Retail pharmacy Tab 10 mg .......................................................................................670.00 30

Hepsera

¾SA0829 Special Authority for Subsidy Initial application only from a gastroenterologist or infectious disease specialist. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 Patient has conﬁrmed Hepatitis B infection (HBsAg+); and Documented resistance to lamivudine, deﬁned as: 2 Patient has raised serum ALT (> 1 × ULN); and 3 Patient has HBV DNA greater than 100,000 copies per mL, or viral load ≥ 10 fold over nadir; and 4 Detection of M204I or M204V mutation; and 5 Either: 5.1 Both: 5.1.1 Patient is cirrhotic; and 5.1.2 adefovir dipivoxil to be used in combination with lamivudine; or 5.2 Both: 5.2.1 Patient is not cirrhotic; and 5.2.2 adefovir dipivoxil to be used as monotherapy. Renewal only from a gastroenterologist or infectious disease specialist. Approvals valid for 2 years where in the opinion of the treating physician, treatment remains appropriate and patient is beneﬁting from treatment. Notes: Lamivudine should be added to adefovir dipivoxil if a patient develops documented resistance to adefovir dipivoxil, deﬁned as: i) raised serum ALT (> 1 × ULN); and ii) HBV DNA greater than 100,000 copies per mL, or viral load ≥ 10 fold over nadir; and iii) Detection of N236T or A181T/V mutation. Adefovir dipivoxil should be stopped 6 months following HBeAg seroconversion for patients who were HBeAg+ prior to commencing adefovir dipivoxil. The recommended dose of adefovir dipivoxil is no more than 10mg daily. In patients with renal insufﬁciency adefovir dipivoxil dose should be reduced in accordance with the datasheet guidelines. Adefovir dipivoxil should be avoided in pregnant women and children. ENTECAVIR – Special Authority see SA0977 on the next page – Retail pharmacy Tab 0.5 mg ......................................................................................400.00 30 Baraclude

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA0977 Special Authority for Subsidy Initial application only from a gastroenterologist or infectious disease specialist. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: All of the following: 1 Patient has conﬁrmed Hepatitis B infection (HBsAg positive for more than 6 months); and 2 Patient is Hepatitis B nucleoside analogue treatment-naive; and 3 Entecavir dose 0.5 mg/day; and 4 Either: 4.1 ALT greater than upper limit of normal; or 4.2 Bridging ﬁbrosis or cirrhosis (Metavir stage 3 or greater) on liver histology; and 5 Either: 5.1 HBeAg positive; or 5.2 patient has ≥ 2,000 IU HBV DNA units per ml and ﬁbrosis (Metavir stage 2 or greater) on liver histology; and 6 No continuing alcohol abuse or intravenous drug use; and 7 Not co-infected with HCV, HIV or HDV; and 8 Neither ALT nor AST greater than 10 times upper limit of normal; and 9 No history of hypersensitivity to entecavir; and 10 No previous documented lamivudine resistance (either clinical or genotypic). Notes: G Entecavir should be continued for 6 months following documentation of complete HBeAg seroconversion (deﬁned as loss of HBeAg plus appearance of anti-HBe plus loss of serum HBV DNA) for patients who were HBeAg positive prior to commencing this agent. This period of consolidation therapy should be extended to 12 months in patients with advanced ﬁbrosis (Metavir Stage F3 or F4). G Entecavir should be taken on an empty stomach to improve absorption. LAMIVUDINE – Special Authority see SA0832 below – Retail pharmacy Tab 100 mg .....................................................................................143.00 28 Zefﬁx Oral liq 5 mg per ml ..........................................................................90.00 240 ml Zefﬁx

¾SA0832 Special Authority for Subsidy Initial application only from a gastroenterologist, infectious disease specialist, paediatrician or general physician. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 Any of the following: 1.1 All of the following: 1.1.1 HBsAg positive for more than 6 months; and 1.1.2 HBeAg positive or HBV DNA positive deﬁned as > 100,000 copies per ml by quantitative PCR at a reference laboratory; and 1.1.3 ALT greater than twice upper limit of normal or bridging ﬁbrosis or cirrhosis (Metavir stage 3 or 4 or equivalent) on liver histology clinical/radiological evidence of cirrhosis; or 1.2 HBV DNA positive cirrhosis prior to liver transplantation; or 1.3 HBsAg positive and have had a liver, kidney, heart, lung or bone marrow transplant; or 1.4 Hepatitis B surface antigen positive (HbsAg) patient who is receiving chemotherapy for a malignancy, or who has received such treatment within the previous two months; and 2 All of the following: 2.1 No continuing alcohol abuse or intravenous drug use; and 2.2 Not coinfected with HCV or HDV; and 2.3 Neither ALT nor AST greater than 10 times upper limit of normal; and 2.4 No history of hypersensitivity to lamivudine; and 2.5 No previous lamivudine therapy with genotypically proven lamivudine resistance. continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . Renewal only from a gastroenterologist, infectious disease specialist, paediatrician or general physician. Approvals valid for 2 years for applications meeting the following criteria: Any of the following: Renewal for patients who have maintained continuous treatment and response to lamivudine 1 All of the following: 1.1 Have maintained continuous treatment with lamivudine; and 1.2 Most recent test result shows continuing biochemical response (normal ALT); and 1.3 HBV DNA <100,00 copies per ml by quantitative PCR at a reference laboratory; or Renewal when given in combination with adefovir dipivoxil for patients with cirrhosis and resistance to lamivudine 2 All of the following: 2.1 Lamivudine to be used in combination with adefovir dipivoxil; and 2.2 Patient is cirrhotic; and Documented resistance to lamivudine, deﬁned as: 2.3 Patient has raised serum ALT (> 1 × ULN); and 2.4 Patient has HBV DNA greater than 100,000 copies per mL, or viral load = 10 fold over nadir; and 2.5 Detection of M204I or M204V mutation; or Renewal when given in combination with adefovir dipivoxil for patients with resistance to adefovir dipivoxil 3 All of the following: 3.1 Lamivudine to be used in combination with adefovir dipivoxil; and Documented resistance to adefovir, deﬁned as: 3.2 Patient has raised serum ALT (> 1 × ULN); and 3.3 Patient has HBV DNA greater than 100,000 copies per mL, or viral load = 10 fold over nadir; and 3.4 Detection of N236T or A181T/V mutation.

Herpesvirus Treatments

ACICLOVIR F Tab dispersible 200 mg .......................................................................1.98 F Tab dispersible 400 mg .......................................................................6.64 F Tab dispersible 800 mg .......................................................................7.38 VALACICLOVIR – Special Authority see SA0957 below – Retail pharmacy Tab 500 mg .....................................................................................102.72 25 56 35 30

Lovir Lovir Lovir Valtrex

¾SA0957 Special Authority for Subsidy Initial application — (recurrent genital herpes) from any medical practitioner. Approvals valid for 12 months where the patient has genital herpes with 2 or more breakthrough episodes in any 6 month period while treated with aciclovir 400 mg twice daily. Renewal — (recurrent genital herpes) from any medical practitioner. Approvals valid for 12 months where the treatment remains appropriate and the patient is beneﬁting from treatment. Initial application — (ophthalmic zoster) from any medical practitioner. Approvals valid without further renewal unless notiﬁed where the patient has previous history of ophthalmic zoster and the patient is at risk of vision impairment. Initial application — (CMV prophylaxis) from any medical practitioner. Approvals valid for 3 months where the patient has undergone organ transplantation.

Hepatitis B/ HIV/AIDS Treatment

TENOFOVIR DISOPROXIL FUMARATE – Subsidy by endorsement; can be waived by Special Authority see SA1047 on the next page Endorsement for treatment of HIV/AIDS: Prescription is deemed to be endorsed if tenofovir disoproxil fumarate is co-prescribed with another anti-retroviral subsidised under Special Authority SA1025 and the prescription is annotated accordingly by the Pharmacist or endorsed by the prescriber. Note: Tenofovir disoproxil fumarate prescribed under endorsement for the treatment of HIV/AIDS is included in the count of up to 4 subsidised antiretrovirals for the purposes of Special Authority SA1025, page 90 Tab 300 mg .....................................................................................531.00 30 Viread

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA1047 Special Authority for Waiver of Rule Initial application — (Conﬁrmed Hepatitis B) only from a gastroenterologist, infectious disease specialist or general physician. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Either: 1 All of the following: 1.1 Patient has conﬁrmed Hepatitis B infection (HBsAg positive for more than 6 months); and 1.2 Patient has had previous lamivudine, adefovir or entecavir therapy; and 1.3 HBV DNA greater than 20,000 IU/mL or increased ≥ 10 fold over nadir; and 1.4 Any of the following: 1.4.1 Lamivudine resistance - detection of M204I/V mutation; or 1.4.2 Adefovir resistance - detection of A181T/V or N236T mutation; or 1.4.3 Entecavir resistance - detection of relevant mutations including I169T, L180M T184S/A/I/L/G/C/M, S202C/G/I, M204V or M250I/V mutation; or 2 Patient is either listed or has undergone liver transplantation for HBV. Initial application — (Pregnant) only from a gastroenterologist, infectious disease specialist or general physician. Approvals valid for 4 months for applications meeting the following criteria: Both: 1 Patient is HBsAg positive and pregnant; and 2 Either: 2.1 HBV DNA > 20,000 IU/mL and ALT > ULN; or 2.2 HBV DNA > 100 million IU/mL and ALT normal. Renewal — (Conﬁrmed Hepatitis B following funded tenofovir treatment for pregnancy within the previous two years) only from a gastroenterologist, infectious disease specialist or general physician. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Either: 1 All of the following: 1.1 Patient has conﬁrmed Hepatitis B infection (HBsAg positive for more than 6 months); and 1.2 Patient has had previous lamivudine, adefovir or entecavir therapy; and 1.3 HBV DNA greater than 20,000 IU/mL or increased ≥ 10 fold over nadir; and 1.4 Any of the following: 1.4.1 Lamivudine resistance - detection of M204I/V mutation; or 1.4.2 Adefovir resistance - detection of A181T/V or N236T mutation; or 1.4.3 Entecavir resistance - detection of relevant mutations including I169T, L180M T184S/A/I/L/G/C/M, S202C/G/I, M204V or M250I/V mutation; or 2 Patient is either listed or has undergone liver transplantation for HBV. Renewal — (Subsequent Pregnancy) only from a gastroenterologist, infectious disease specialist or general physician. Approvals valid for 4 months for applications meeting the following criteria: Both: 1 Patient is HBsAg positive and pregnant; and 2 Either: 2.1 HBV DNA > 20,000 IU/mL and ALT > ULN; or 2.2 HBV DNA > 100 million IU/mL and ALT normal. Notes: G Tenofovir disoproxil fumarate should be stopped 6 months following HBeAg seroconversion for patients who were HBeAg positive prior to commencing this agent and 6 months following HBsAg seroconversion for patients who were HBeAg negative prior to commencing this agent. G The recommended dose of Tenofovir disoproxil fumarate for the treatment of all three indications is 300 mg once daily. G In patients with renal insufﬁciency (calculated creatinine clearance less than 50ml/min), Tenofovir disoproxil fumarate dose should be reduced in accordance with the approved Medsafe datasheet guidelines. G Tenofovir disoproxil fumarate is not approved for use in children.

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Antiretrovirals

¾SA1025 Special Authority for Subsidy Initial application — (Conﬁrmed HIV/AIDS) only from a named specialist. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Both: 1 Conﬁrmed HIV infection; and 2 Any of the following: 2.1 Symptomatic patient; or 2.2 Patient aged 12 months and under; or 2.3 Both: 2.3.1 Patient aged 1 to 5 years; and 2.3.2 Any of the following: 2.3.2.1 CD4 counts < 1000 cells/mm3 ; or 2.3.2.2 CD4 counts < 0.25 × total lymphocyte count; or 2.3.2.3 Viral load counts > 100000 copies per ml; or 2.4 Both: 2.4.1 Patient aged 6 years and over; and 2.4.2 CD4 counts < 350 cells/mm3 . Notes: Tenofovir disoproxil fumarate prescribed under endorsement for HIV/AIDS is included in the count of up to 4 subsidised antiretrovirals. Subsidies for a combination of up to four antiretroviral medications. The combination of a protease inhibitor and low-dose ritonavir given as a booster (either as part of a combination product or separately) will be counted as one protease inhibitor for the purpose of accessing funding to antiretrovirals. Renewal — (Conﬁrmed HIV/AIDS) only from a named specialist. Approvals valid without further renewal unless notiﬁed where the treatment remains appropriate and the patient is beneﬁting from treatment. Initial application — (Prevention of maternal transmission) only from a named specialist. Approvals valid for 1 year for applications meeting the following criteria: Either: 1 Prevention of maternal foetal transmission; or 2 Treatment of the newborn for up to eight weeks. Notes: Tenofovir disoproxil fumarate prescribed under endorsement for HIV/AIDS is included in the count of up to 4 subsidised antiretrovirals. Subsidies for a combination of up to four antiretroviral medications. The combination of a protease inhibitor and low-dose ritonavir given as a booster (either as part of a combination product or separately) will be counted as one protease inhibitor for the purpose of accessing funding to antiretrovirals. Some antiretrovirals are unapproved or contraindicated for this indication. Practitioners prescribing these medications should exercise their own skill, judgement, expertise and discretion, and make their own prescribing decisions with respect to the use of a Pharmaceutical for an indication for which it is not approved or contraindicated. Initial application — (post-exposure prophylaxis following non-occupational exposure to HIV) only from a named specialist. Approvals valid for 4 weeks for applications meeting the following criteria: Both: 1 Treatment course to be initiated within 72 hours post exposure; and 2 Either: 2.1 Patient has had unprotected receptive anal intercourse with a known HIV positive person; or 2.2 Patient has shared intravenous injecting equipment with a known HIV positive person. Notes: Tenofovir disoproxil fumarate prescribed under endorsement for HIV/AIDS is included in the count of up to 4 subsidised antiretrovirals. continued. . .

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . Subsidies for a combination of up to four antiretroviral medications. The combination of a protease inhibitor and low-dose ritonavir given as a booster (either as part of a combination product or separately) will be counted as one protease inhibitor for the purpose of accessing funding to antiretrovirals. Renewal — (second or subsequent post-exposure prophylaxis) only from a named specialist. Approvals valid for 4 weeks for applications meeting the following criteria: Both: 1 Treatment course to be initiated within 72 hours post exposure; and 2 Either: 2.1 Patient has had unprotected receptive anal intercourse with a known HIV positive person; or 2.2 Patient has shared intravenous injecting equipment with a known HIV positive person. Initial application — (Percutaneous exposure) only from a named specialist. Approvals valid for 6 weeks where the patient has percutaneous exposure to blood known to be HIV positive. Notes: Tenofovir disoproxil fumarate prescribed under endorsement for HIV/AIDS is included in the count of up to 4 subsidised antiretrovirals. Subsidies for a combination of up to four antiretroviral medications. The combination of a protease inhibitor and low-dose ritonavir given as a booster (either as part of a combination product or separately) will be counted as one protease inhibitor for the purpose of accessing funding to antiretrovirals. Renewal — (Second or subsequent percutaneous exposure) only from a named specialist. Approvals valid for 6 weeks where the patient has percutaneous exposure to blood known to be HIV positive.

Non-nucleosides Reverse Transcriptase Inhibitors

EFAVIRENZ – Special Authority see SA1025 on the preceding page – Retail pharmacy Tab 50 mg .......................................................................................158.33 30 Tab 200 mg .....................................................................................474.99 90 Tab 600 mg .....................................................................................474.99 30 ETRAVIRINE – Special Authority see SA1025 on the preceding page – Retail pharmacy Tab 100 mg .....................................................................................770.00 120 NEVIRAPINE – Special Authority see SA1025 on the preceding page – Retail pharmacy Tab 200 mg .....................................................................................319.80 60 Oral suspension 10 mg per ml ........................................................134.55 240 ml

Stocrin S29 Stocrin Stocrin Intelence Viramune Viramune

Suspension

Nucleosides Reverse Transcriptase Inhibitors

ABACAVIR SULPHATE – Special Authority see SA1025 on the preceding page – Retail pharmacy Tab 300 mg .....................................................................................229.00 60 Ziagen Oral liq 20 mg per ml ........................................................................50.00 240 ml OP Ziagen ABACAVIR SULPHATE WITH LAMIVUDINE – Special Authority see SA1025 on the preceding page – Retail pharmacy Note: Kivexa counts as two anti-retroviral medications for the purposes of the anti-retroviral Special Authority. Tab 600 mg with lamivudine 300 mg ..............................................630.00 30 Kivexa DIDANOSINE [DDI] – Special Authority see SA1025 on the preceding page – Retail pharmacy Cap 125 mg ....................................................................................115.05 30 Cap 200 mg ....................................................................................184.08 30 Cap 250 mg ....................................................................................230.10 30 Cap 400 mg ....................................................................................368.16 30 EMTRICITABINE – Special Authority see SA1025 on the preceding page – Retail pharmacy Cap 200 mg ....................................................................................307.20 30

Videx EC Videx EC Videx EC Videx EC Emtriva

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

LAMIVUDINE – Special Authority see SA1025 on page 90 – Retail pharmacy Tab 150 mg .....................................................................................153.60 Oral liq 10 mg per ml ........................................................................50.00 STAVUDINE [D4T] – Special Authority see SA1025 on page 90 – Retail pharmacy Cap 30 mg ......................................................................................377.80 Cap 40 mg ......................................................................................503.80

60 240 ml OP 60 60

3TC 3TC Zerit Zerit Retrovir Retrovir

ZIDOVUDINE [AZT] – Special Authority see SA1025 on page 90 – Retail pharmacy Cap 100 mg ....................................................................................145.00 100 Oral liq 10 mg per ml ........................................................................29.00 200 ml OP

ZIDOVUDINE [AZT] WITH LAMIVUDINE – Special Authority see SA1025 on page 90 – Retail pharmacy Combivir counts as two anti-retroviral medications for the purposes of the anti-retroviral Special Authority. Tab 300 mg with lamivudine 150 mg ..............................................667.20 60 Combivir

Protease Inhibitors

ATAZANAVIR SULPHATE – Special Authority see SA1025 on page 90 – Retail pharmacy Cap 150 mg ....................................................................................568.34 60 Cap 200 mg ....................................................................................757.79 60 DARUNAVIR – Special Authority see SA1025 on page 90 – Retail pharmacy Tab 300 mg .................................................................................1,190.00 Tab 400 mg .....................................................................................837.50 Tab 600 mg ..................................................................................1,190.00 (Prezista Tab 300 mg to be delisted 1 January 2012) INDINAVIR – Special Authority see SA1025 on page 90 – Retail pharmacy Cap 200 mg ....................................................................................519.75 Cap 400 mg ....................................................................................519.75 120 60 60

Reyataz Reyataz Prezista Prezista Prezista

360 180

Crixivan Crixivan Kaletra Kaletra Kaletra Norvir Norvir

LOPINAVIR WITH RITONAVIR – Special Authority see SA1025 on page 90 – Retail pharmacy Tab 100 mg with ritonavir 25 mg .....................................................183.75 60 Tab 200 mg with ritonavir 50 mg .....................................................735.00 120 Oral liq 80 mg with ritonavir 20 mg per ml ......................................735.00 300 ml OP RITONAVIR – Special Authority see SA1025 on page 90 – Retail pharmacy Tab 100 mg .......................................................................................43.31 Oral liq 80 mg per ml ......................................................................103.98 30 90 ml OP

Strand Transfer Inhibitors

RALTEGRAVIR POTASSIUM – Special Authority see SA1025 on page 90 – Retail pharmacy Tab 400 mg ..................................................................................1,090.00 60

Isentress

Antiretrovirals - Additional Therapies HIV Fusion Inhibitors

ENFUVIRTIDE – Special Authority see SA0845 on the next page – Retail pharmacy Powder for inj 90 mg per ml × 60 ................................................2,380.00 1

Fuzeon

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA0845 Special Authority for Subsidy Initial application only from a named specialist. Approvals valid for 3 months for applications meeting the following criteria: All of the following: 1 Conﬁrmed HIV infection; and 2 Enfuvirtide to be given in combination with optimized background therapy (including at least 1 other antiretroviral drug that the patient has never previously been exposed to) for treatment failure; and 3 Either: 3.1 Patient has evidence of HIV replication, despite ongoing therapy; or 3.2 Patient has treatment-limiting toxicity to previous antiretroviral agents; and 4 Previous treatment with 3 different antiretroviral regimens has failed; and 5 All of the following: 5.1 Previous treatment with a non-nucleoside reverse transcriptase inhibitor has failed; and 5.2 Previous treatment with a nucleoside reverse transcriptase inhibitor has failed; and 5.3 Previous treatment with a protease inhibitor has failed. Renewal only from a named specialist. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 Evidence of at least a 10 fold reduction in viral load at 12; and 2 The treatment remains appropriate and the patient is beneﬁting from treatment.

Immune Modulators

Guidelines for the use of interferon in the treatment of hepatitis C: Physicians considering treatment of patients with hepatitis C should discuss cases with a gastroenterologist or an infectious disease physician. All subjects undergoing treatment require careful monitoring for side effects. Patients should be otherwise ﬁt. Hepatocellular carcinoma should be excluded by ultrasound examination and alpha-fetoprotein level. Criteria for Treatment 1) Diagnosis G Anti-HCV positive on at least two occasions with a positive PCR for HCV-RNA and preferably conﬁrmed by a supplementary RIBA test; or G PCR-RNA positive for HCV on at least 2 occasions if antibody negative; or G Anti-HCV positive on at least two occasions with a positive supplementary RIBA test with a negative PCR for HCV RNA but with a liver biopsy consistent with 2(b) following. 2) Establishing Active Chronic Liver Disease G Conﬁrmed HCV infection and serum ALT/AST levels measured on at least three occasions over six months averaging > 1.5 × upper limit of normal. (ALT is the preferable enzyme); or G Liver biopsy showing signiﬁcant inﬂammatory activity (active hepatitis) with or without cirrhosis. This is not a necessary requirement for those patients with coagulopathy. (Some patients have active disease on histology with normal transaminase enzymes). Exclusion Criteria 1) Autoimmune liver disease. (Interferon may exacerbate autoimmune liver disease as well as other autoimmune diseases such as thyroid disease). 2) Pregnancy. 3) Neutropenia (<2.0 × 109 ) and/or thrombocytopenia. 4) Continuing alcohol abuse and/or continuing intravenous drug users. Dosage The current recommended dosage is 3 million units of interferon alpha-2a or interferon alpha-2b administered subcutaneously 3 times a week for 52 weeks (twelve months) Exit Criteria The patient’s response to interferon treatment should be reviewed at either three or four months. Interferon treatment should be discontinued in patients who do not show a substantial reduction (50%) in their mean pre-treatment ALT level at this stage.

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

INTERFERON ALPHA-2A – PCT – Retail pharmacy-Specialist See prescribing guideline on the preceding page Inj 3 m iu preﬁlled syringe .................................................................31.32 Inj 6 m iu preﬁlled syringe .................................................................62.64 Inj 9 m iu preﬁlled syringe .................................................................93.96 INTERFERON ALPHA-2B – PCT – Retail pharmacy-Specialist See prescribing guideline on the preceding page Inj 18 m iu, 1.2 ml multidose pen ....................................................187.92 Inj 30 m iu, 1.2 ml multidose pen ....................................................313.20 Inj 60 m iu, 1.2 ml multidose pen ....................................................626.40

1 1 1

Roferon-A Roferon-A Roferon-A

1 1 1

Intron-A Intron-A Intron-A

PEGYLATED INTERFERON ALPHA-2A – Special Authority see SA1134 below – Retail pharmacy See prescribing guideline on the preceding page Inj 135 µg preﬁlled syringe .............................................................362.00 1 Pegasys 1,448.00 4 Pegasys Inj 180 µg preﬁlled syringe .............................................................450.00 1 Pegasys 1,800.00 4 Pegasys Inj 135 µg preﬁlled syringe × 4 with ribavirin tab 200 mg × 112 ....................................................................................... 1,799.68 1 OP Pegasys RBV Combination Pack Inj 135 µg preﬁlled syringe × 4 with ribavirin tab 200 mg × 168 ....................................................................................... 1,975.00 1 OP Pegasys RBV Combination Pack Inj 180 µg preﬁlled syringe × 4 with ribavirin tab 200 mg × 112 ....................................................................................... 2,059.84 1 OP Pegasys RBV Combination Pack Inj 180 µg preﬁlled syringe × 4 with ribavirin tab 200 mg × 168 ....................................................................................... 2,190.00 1 OP Pegasys RBV Combination Pack ¾SA1134 Special Authority for Subsidy Initial application — (chronic hepatitis C - genotype 1, 4, 5 or 6 infection or co-infection with HIV) from any specialist. Approvals valid for 18 months for applications meeting the following criteria: Both: 1 Either: 1.1 Patient has chronic hepatitis C, genotype 1, 4, 5 or 6 infection; or 1.2 Patient has chronic hepatitis C and is co-infected with HIV; and 2 Maximum of 48 weeks therapy. Notes: G Consider stopping treatment if there is absence of a virological response (deﬁned as at least a 2-log reduction in viral load) following 12 weeks of treatment since this is predictive of treatment failure. G Consider reducing treatment to 24 weeks if serum HCV RNA level at Week 4 is undetectable by sensitive PCR assay (less than 50IU/ml) AND Baseline serum HCV RNA is less than 400,000IU/ml Initial application — (chronic hepatitis C - genotype 2 or 3 infection without co-infection with HIV) from any specialist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 Patient has chronic hepatitis C, genotype 2 or 3 infection; and 2 Maximum of 6 months therapy. Initial application — (Hepatitis B) only from a gastroenterologist, infectious disease specialist or general physician. Approvals valid for 18 months for applications meeting the following criteria: All of the following: continued. . .

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 1 Patient has conﬁrmed Hepatitis B infection (HBsAg positive for more than 6 months); and 2 Patient is Hepatitis B treatment-naive; and 3 ALT > 2 times Upper Limit of Normal; and 4 HBV DNA < 10 log10 IU/ml; and 5 Either: 5.1 HBeAg positive; or 5.2 serum HBV DNA ≥ 2,000 units/ml and signiﬁcant ﬁbrosis (≥ Metavir Stage F2); and 6 Compensated liver disease; and 7 No continuing alcohol abuse or intravenous drug use; and 8 Not co-infected with HCV, HIV or HDV; and 9 Neither ALT nor AST > 10 times upper limit of normal; and 10 No history of hypersensitivity or contraindications to pegylated interferon; and 11 Maximum of 48 weeks therapy. Notes: G Approved dose is 180 µg once weekly. G The recommended dose of Pegylated Interferon-alpha 2a is 180 µg once weekly. G In patients with renal insufﬁciency (calculated creatinine clearance less than 50ml/min), Pegylated Interferon-alpha 2a dose should be reduced to 135 µg once weekly. G In patients with neutropaenia and thrombocytopaenia, dose should be reduced in accordance with the datasheet guidelines. G Pegylated Interferon-alpha 2a is not approved for use in children.

Urinary Tract Infections

HEXAMINE HIPPURATE F Tab 1 g ..............................................................................................18.40 (38.10) NITROFURANTOIN F Tab 50 mg – For nitrofurantoin oral liquid formulation refer, page 172 .................................................................................... 22.20 F Tab 100 mg .......................................................................................37.50 NORFLOXACIN Tab 400 mg – Maximum of 6 tab per prescription; can be waived by endorsement - Retail pharmacy - Specialist.............. 15.45 100 Hiprex

100 100

Nifuran Nifuran

100

Arrow-Norﬂoxacin

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

INFECTIONS - AGENTS FOR SYSTEMIC USE

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Vaccines Inﬂuenza vaccine

INFLUENZA VACCINE – Hospital pharmacy [Xpharm] A) is available 1 March until vaccine supplies are exhausted each year for patients who meet the following criteria, as set by the Ministry of Health: a) all people 65 years of age and over; b) people under 65 years of age with: i) the following cardiovascular disease: 1) ischaemic heart disease, 2) congestive heart disease, 3) rheumatic heart disease, 4) congenital heart disease, or 5) cerebo-vascular disease; ii) the following chronic respiratory disease: 1) asthma, if on a regular preventative therapy, or 2) other chronic respiratory disease with impaired lung function; iii) diabetes; iv) chronic renal disease; v) any cancer, excluding basal and squamous skin cancers if not invasive; vi) the following other conditions: a) autoimmune disease, b) immune suppression, c) HIV, d) transplant recipients, e) neuromuscular and CNS diseases, f) haemoglobinopathies, g) children on long term aspirin, or h) pregnancy. c) people under 18 years of age living within the boundaries of the Canterbury District Health Board. The following conditions are excluded from funding: a) asthma not requiring regular preventative therapy, b) hypertension and/or dyslipidaemia without evidence of end-organ disease, B) Doctors are the only Contractors entitled to claim payment from the Funder for the supply of inﬂuenza vaccine to patients eligible under the above criteria for subsidised immunisation and they may only do so in respect of the inﬂuenza vaccine listed in the Pharmaceutical Schedule. C) Individual DHBs may fund patients over and above the above criteria. The claiming process for these additional patients should be determined between the DHB and Contractor. D) Inﬂuenza Vaccine does not fall within the deﬁnition Community Pharmaceutical as it is not funded directly from the Pharmaceutical Budget. Pharmacists are unable to claim for the dispensing of inﬂuenza vaccine from the Funder. Inj ......................................................................................................90.00 10 Fluarix Fluvax

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Anticholinesterases

NEOSTIGMINE Inj 2.5 mg per ml, 1 ml ....................................................................140.00 PYRIDOSTIGMINE BROMIDE L Tab 60 mg .........................................................................................38.90 50 100

AstraZeneca Mestinon

Non-steroidal Anti-inﬂammatory Drugs (NSAIDs)

¾SA1038 Special Authority for Manufacturers Price Note: Subsidy for patients with existing approvals prior to 1 September 2010. Approvals valid without further renewal unless notiﬁed. No new approvals will be granted from 1 September 2010. DICLOFENAC SODIUM F Tab EC 25 mg .....................................................................................1.63 50 Diclofenac Sandoz F Tab 50 mg dispersible – Additional subsidy by Special Authority see SA1038 above – Retail pharmacy .............................1.50 20 (8.00) Voltaren D F Tab EC 50 mg .....................................................................................2.13 50 Diclofenac Sandoz F Tab long-acting 75 mg ......................................................................32.80 500 Diclax SR F Tab long-acting 100 mg ....................................................................63.22 500 Diclax SR F Inj 25 mg per ml, 3 ml .......................................................................12.00 5 Voltaren Up to 5 inj available on a PSO F Suppos 12.5 mg .................................................................................1.85 10 Voltaren F Suppos 25 mg ....................................................................................2.22 10 Voltaren F Suppos 50 mg ....................................................................................3.84 10 Voltaren Up to 10 supp available on a PSO F Suppos 100 mg ..................................................................................6.36 10 Voltaren IBUPROFEN – Additional subsidy by Special Authority see SA1038 above – Retail pharmacy F Tab 200 mg .......................................................................................12.75 1,000 16.00 F Tab 400 mg .........................................................................................1.07 30 (4.56) F Tab 600 mg .........................................................................................1.60 30 (6.84) F Tab long-acting 800 mg ......................................................................8.12 30 F‡ Oral liq 100 mg per 5 ml .....................................................................2.69 200 ml KETOPROFEN F Cap long-acting 100 mg ...................................................................21.56 F Cap long-acting 200 mg ...................................................................43.12 100 100

Arrowcare Ethics Ibuprofen

Brufen Brufen

Brufen SR Fenpaed Oruvail SR Oruvail SR

MEFENAMIC ACID – Additional subsidy by Special Authority see SA1038 above – Retail pharmacy F Cap 250 mg ........................................................................................0.50 20 (5.60) Ponstan 1.25 50 (9.16) Ponstan NAPROXEN F Tab 250 mg .......................................................................................23.70 F Tab 500 mg .......................................................................................24.88 F Tab long-acting 750 mg ....................................................................18.00 F Tab long-acting 1,000 mg .................................................................21.00 500 250 90 90

Noﬂam 250 Noﬂam 500 Naprosyn SR 750 Naprosyn SR 1000

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

SULINDAC – Additional subsidy by Special Authority see SA1038 on the preceding page – Retail pharmacy F Tab 100 mg .........................................................................................5.32 100 (17.10) Daclin F Tab 200 mg .........................................................................................6.72 100 (30.20) Daclin TENOXICAM F Tab 20 mg .........................................................................................23.75 F Inj 20 mg .............................................................................................9.95 TIAPROFENIC ACID F Tab 300 mg .......................................................................................19.26 100 1 60

Tilcotil AFT Surgam

NSAIDs Other

INDOMETHACIN F Suppos 100 mg ................................................................................14.50 MELOXICAM – Special Authority see SA1034 below – Retail pharmacy Tab 7.5 mg ........................................................................................11.50 30 30

Arthrexin Arrow-Meloxicam

¾SA1034 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: All of the following: 1 The patient has moderate to severe haemophilia with less than or equal to 5% of normal circulating functional clotting factor; and 2 The patient has haemophilic arthropathy; and 3 Pain and inﬂammation associated with haemophilic arthropathy is inadequately controlled by alternative funded treatment options, or alternative funded treatment options are contraindicated.

Antirheumatoid Agents

AURANOFIN Tab 3 mg ...........................................................................................68.99 LEFLUNOMIDE Tab 10 mg .........................................................................................55.00 79.27 Tab 20 mg .........................................................................................76.00 108.60 Tab 100 mg .......................................................................................54.44 PENICILLAMINE Tab 125 mg .......................................................................................61.93 Tab 250 mg .......................................................................................98.98 SODIUM AUROTHIOMALATE Inj 10 mg per 0.5 ml ..........................................................................76.87 Inj 20 mg per 0.5 ml ........................................................................113.17 Inj 50 mg per 0.5 ml ........................................................................217.23 60 30 30 3 100 100 10 10 10

Ridaura AFT-Leﬂunomide Arava AFT-Leﬂunomide Arava Arava D-Penamine D-Penamine Myocrisin Myocrisin Myocrisin

Tumour Necrosis Factor (TNF) Inhibitors

ADALIMUMAB – Special Authority see SA1156 on the next page – Retail pharmacy Inj 40 mg per 0.8 ml preﬁlled pen ................................................1,799.92 Inj 40 mg per 0.8 ml preﬁlled syringe ..........................................1,799.92 2 2

HumiraPen Humira

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA1156 Special Authority for Subsidy Initial application — (rheumatoid arthritis) only from a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has had an initial Special Authority approval for etanercept for rheumatoid arthritis; and 1.2 Either: 1.2.1 The patient has experienced intolerable side effects from etanercept; or 1.2.2 The patient has received insufﬁcient beneﬁt from etanercept to meet the renewal criteria for etanercept for rheumatoid arthritis; or 2 All of the following: 2.1 Patient has had severe and active erosive rheumatoid arthritis for six months duration or longer; and 2.2 Treatment is to be used as an adjunct to methotrexate therapy or monotherapy where use of methotrexate is limited by toxicity or intolerance; and 2.3 Patient has tried and not responded to at least three months of oral or parenteral methotrexate at a dose of at least 20 mg weekly or a maximum tolerated dose; and 2.4 Patient has tried and not responded to at least three months of oral or parenteral methotrexate in combination with sulphasalazine and hydroxychloroquine sulphate (at maximum tolerated doses); and 2.5 Any of the following: 2.5.1 Patient has tried and not responded to at least three months of oral or parenteral methotrexate in combination with the maximum tolerated dose of cyclosporin; or 2.5.2 Patient has tried and not responded to at least three months of oral or parenteral methotrexate in combination with intramuscular gold; or 2.5.3 Patient has tried and not responded to at least three months of therapy at the maximum tolerated dose of leﬂunomide alone or in combination with oral or parenteral methotrexate; and 2.6 Either: 2.6.1 Patient has persistent symptoms of poorly controlled and active disease in at least 20 swollen, tender joints; or 2.6.2 Patient has persistent symptoms of poorly controlled and active disease in at least four joints from the following: wrist, elbow, knee, ankle, and either shoulder or hip; and 2.7 Either: 2.7.1 Patient has a C-reactive protein level greater than 15 mg/L measured no more than one month prior to the date of this application; or 2.7.2 C-reactive protein levels not measured as patient is currently receiving prednisone therapy at a dose of greater than 5 mg per day and has done so for more than three months. Initial application — (Crohn’s disease) only from a gastroenterologist. Approvals valid for 3 months for applications meeting the following criteria: All of the following: 1 Patient has severe active Crohn’s disease; and 2 Any of the following: 2.1 Patient has a Crohn’s Disease Activity Index (CDAI) score of greater than or equal to 300; or 2.2 Patient has extensive small intestine disease affecting more than 50 cm of the small intestine; or 2.3 Patient has evidence of short gut syndrome or would be at risk of short gut syndrome with further bowel resection; or 2.4 Patient has an ileostomy or colostomy, and has intestinal inﬂammation; and 3 Patient has tried but had an inadequate response to, or has experienced intolerable side effects from, prior systemic therapy with immunomodulators at maximum tolerated doses (unless contraindicated) and corticosteroids; and 4 Surgery (or further surgery) is considered to be clinically inappropriate. Initial application — (severe chronic plaque psoriasis) only from a dermatologist. Approvals valid for 4 months for applications meeting the following criteria: Either: continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 1 Both: 1.1 The patient has had an initial Special Authority approval for etanercept for severe chronic plaque psoriasis; and 1.2 Either: 1.2.1 The patient has experienced intolerable side effects from etanercept; or 1.2.2 The patient has received insufﬁcient beneﬁt from etanercept to meet the renewal criteria for etanercept for severe chronic plaque psoriasis; or 2 All of the following: 2.1 Either: 2.1.1 Patient has "whole body" severe chronic plaque psoriasis with a Psoriasis Area and Severity Index (PASI) score of greater than 15, where lesions have been present for at least 6 months from the time of initial diagnosis; or 2.1.2 Patient has severe chronic plaque psoriasis of the face, or palm of a hand or sole of a foot, where the plaque or plaques have been present for at least 6 months from the time of initial diagnosis; and 2.2 Patient has tried, but had an inadequate response (see Note) to, or has experienced intolerable side effects from, at least three of the following (at maximum tolerated doses unless contraindicated): phototherapy, methotrexate, cyclosporin, or acitretin; and 2.3 A PASI assessment has been completed for at least the most recent prior treatment course (but preferably all prior treatment courses), preferably while still on treatment but no longer than 1 month following cessation of each prior treatment course; and 2.4 The most recent PASI assessment is no more than 1 month old at the time of application. Note: "Inadequate response" is deﬁned as: for whole body severe chronic plaque psoriasis, a PASI score of greater than 15, as assessed preferably while still on treatment but no longer than 1 month following cessation of the most recent prior treatment; for severe chronic plaque psoriasis of the face, hand or foot, at least 2 of the 3 PASI symptom subscores for erythema, thickness and scaling are rated as severe or very severe, and the skin area affected is 30% or more of the face, palm of a hand or sole of a foot, as assessed preferably while still on treatment but no longer than 1 month following cessation of the most recent prior treatment. Initial application — (ankylosing spondylitis) only from a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has had an initial Special Authority approval for etanercept for ankylosing spondylitis; and 1.2 Either: 1.2.1 The patient has experienced intolerable side effects from etanercept; or 1.2.2 The patient has received insufﬁcient beneﬁt from etanercept to meet the renewal criteria for etanercept for ankylosing spondylitis; or 2 All of the following: 2.1 Patient has a conﬁrmed diagnosis of ankylosing spondylitis for more than six months; and 2.2 Patient has low back pain and stiffness that is relieved by exercise but not by rest; and 2.3 Patient has bilateral sacroiliitis demonstrated by plain radiographs, CT or MRI scan; and 2.4 Patient’s ankylosing spondylitis has not responded adequately to treatment with two or more non-steroidal antiinﬂammatory drugs (NSAIDs), in combination with anti-ulcer therapy if indicated, while patient was undergoing at least 3 months of an exercise regime supervised by a physiotherapist; and 2.5 Either: 2.5.1 Patient has limitation of motion of the lumbar spine in the sagittal and the frontal planes as determined by the following Bath Ankylosing Spondylitis Metrology Index (BASMI) measures: a modiﬁed Schober’s test of less than or equal to 4 cm and lumbar side ﬂexion measurement of less than or equal to 10 cm (mean of left and right); or 2.5.2 Patient has limitation of chest expansion by at least 2.5 cm below the following average normal values corrected for age and gender (see Notes); and 2.6 A Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) of at least 6 on a 0-10 scale. continued. . .

100

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . .

Notes: The BASDAI must have been determined at the completion of the 3 month exercise trial, but prior to ceasing NSAID treatment. The BASDAI measure must be no more than 1 month old at the time of initial application. Average normal chest expansion corrected for age and gender: 18-24 years - Male: 7.0 cm; Female: 5.5 cm 25-34 years - Male: 7.5 cm; Female: 5.5 cm 35-44 years - Male: 6.5 cm; Female: 4.5 cm 45-54 years - Male: 6.0 cm; Female: 5.0 cm 55-64 years - Male: 5.5 cm; Female: 4.0 cm 65-74 years - Male: 4.0 cm; Female: 4.0 cm 75+ years - Male: 3.0 cm; Female: 2.5 cm Initial application — (psoriatic arthritis) only from a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has had an initial Special Authority approval for etanercept for psoriatic arthritis; and 1.2 Either: 1.2.1 The patient has experienced intolerable side effects from etanercept; or 1.2.2 The patient has received insufﬁcient beneﬁt from etanercept to meet the renewal criteria for etanercept for psoriatic arthritis; or 2 All of the following: 2.1 Patient has had severe active psoriatic arthritis for six months duration or longer; and 2.2 Patient has tried and not responded to at least three months of oral or parenteral methotrexate at a dose of at least 20 mg weekly or a maximum tolerated dose; and 2.3 Patient has tried and not responded to at least three months of sulphasalazine at a dose of at least 2 g per day or leﬂunomide at a dose of up to 20 mg daily (or maximum tolerated doses); and 2.4 Either: 2.4.1 Patient has persistent symptoms of poorly controlled and active disease in at least 15 swollen, tender joints; or 2.4.2 Patient has persistent symptoms of poorly controlled and active disease in at least four joints from the following: wrist, elbow, knee, ankle, and either shoulder or hip; and 2.5 Any of the following: 2.5.1 Patient has a C-reactive protein level greater than 15 mg/L measured no more than one month prior to the date of this application; or 2.5.2 Patient has an elevated erythrocyte sedimentation rate (ESR) greater than 25 mm per hour; or 2.5.3 ESR and CRP not measured as patient is currently receiving prednisone therapy at a dose of greater than 5 mg per day and has done so for more than three months. Renewal — (rheumatoid arthritis) only from a rheumatologist or Practitioner on the recommendation of a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Either: 1.1 Applicant is a rheumatologist; or 1.2 Applicant is a Practitioner and conﬁrms that a rheumatologist has provided a letter, email or fax recommending that the patient continues with adalimumab treatment; and 2 Treatment is to be used as an adjunct to methotrexate therapy or monotherapy where use of methotrexate is limited by toxicity or intolerance; and 3 Either: 3.1 Following 3 to 4 months’ initial treatment, the patient has at least a 50% decrease in active joint count from baseline and a clinically signiﬁcant response to treatment in the opinion of the physician; or continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

101

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 3.2 On subsequent reapplications, the patient demonstrates at least a continuing 30% improvement in active joint count from baseline and a clinically signiﬁcant response to treatment in the opinion of the physician; and 4 Either: 4.1 Adalimumab to be administered at doses no greater than 40 mg every 14 days; or 4.2 Patient cannot take concomitant methotrexate and requires doses of adalimumab higher than 40 mg every 14 days to maintain an adequate response. Renewal — (Crohn’s disease) only from a gastroenterologist or Practitioner on the recommendation of a gastroenterologist. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Either: 1.1 Applicant is a gastroenterologist; or 1.2 Applicant is a Practitioner and conﬁrms that a gastroenterologist has provided a letter, email or fax recommending that the patient continues with adalimumab treatment; and 2 Either: 2.1 Either: 2.1.1 CDAI score has reduced by 100 points from the CDAI score when the patient was initiated on adalimumab; or 2.1.2 CDAI score is 150 or less; or 2.2 Both: 2.2.1 The patient has demonstrated an adequate response to treatment but CDAI score cannot be assessed; and 2.2.2 Applicant to indicate the reason that CDAI score cannot be assessed; and 3 Adalimumab to be administered at doses no greater than 40 mg every 14 days. Renewal — (severe chronic plaque psoriasis) only from a dermatologist or Practitioner on the recommendation of a dermatologist. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Either: 1.1 Applicant is a dermatologist; or 1.2 Applicant is a Practitioner and conﬁrms that a dermatologist has provided a letter, email or fax recommending that the patient continues with adalimumab treatment; and 2 Either: 2.1 Both: 2.1.1 Patient had "whole body" severe chronic plaque psoriasis at the start of treatment; and 2.1.2 Following each prior adalimumab treatment course the patient has a PASI score which is reduced by 75% or more, or is sustained at this level, when compared with the pre-adalimumab treatment baseline value; or 2.2 Both: 2.2.1 Patient had severe chronic plaque psoriasis of the face, or palm of a hand or sole of a foot at the start of treatment; and 2.2.2 Either: 2.2.2.1 Following each prior adalimumab treatment course the patient has a reduction in the PASI symptom subscores for all 3 of erythema, thickness and scaling, to slight or better, or sustained at this level, as compared to the treatment course baseline values; or 2.2.2.2 Following each prior adalimumab treatment course the patient has a reduction of 75% or more in the skin area affected, or sustained at this level, as compared to the pre-adalimumab treatment baseline value; and 3 Adalimumab to be administered at doses no greater than 40 mg every 14 days. Note: A treatment course is deﬁned as a minimum of 12 weeks adalimumab treatment Renewal — (ankylosing spondylitis) only from a rheumatologist or Practitioner on the recommendation of a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Either: continued. . .

102

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 1.1 Applicant is a rheumatologist; or 1.2 Applicant is a Practitioner and conﬁrms that a rheumatologist has provided a letter, email or fax recommending that the patient continues with adalimumab treatment; and 2 Following 12 weeks of adalimumab treatment, BASDAI has improved by 4 or more points from pre-adalimumab baseline on a 10 point scale, or by 50%, whichever is less; and 3 Physician considers that the patient has beneﬁted from treatment and that continued treatment is appropriate; and 4 Adalimumab to be administered at doses no greater than 40 mg every 14 days. Renewal — (psoriatic arthritis) only from a rheumatologist or Practitioner on the recommendation of a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Either: 1.1 Applicant is a rheumatologist; or 1.2 Applicant is a Practitioner and conﬁrms that a rheumatologist has provided a letter, email or fax recommending that the patient continues with adalimumab treatment; and 2 Either: 2.1 Following 3 to 4 months’ initial treatment, the patient has at least a 50% decrease in active joint count from baseline and a clinically signiﬁcant response to treatment in the opinion of the physician; or 2.2 The patient demonstrates at least a continuing 30% improvement in active joint count from baseline and a clinically signiﬁcant response to prior adalimumab treatment in the opinion of the treating physician; and 3 Adalimumab to be administered at doses no greater than 40 mg every 14 days. ETANERCEPT – Special Authority see SA1157 below – Retail pharmacy 4 Enbrel Inj 25 mg .........................................................................................949.96 Inj 50 mg autoinjector ..................................................................1,899.92 4 Enbrel Inj 50 mg preﬁlled syringe ...........................................................1,899.92 4 Enbrel ¾SA1157 Special Authority for Subsidy Initial application — (juvenile idiopathic arthritis) only from a named specialist or rheumatologist. Approvals valid for 4 months for applications meeting the following criteria: All of the following: 1 To be used as an adjunct to methotrexate therapy or monotherapy where use of methotrexate is limited by toxicity or intolerance; and 2 Patient diagnosed with Juvenile Idiopathic Arthritis (JIA); and 3 Patient has had severe active polyarticular course JIA for 6 months duration or longer; and 4 Patient has tried and not responded to at least three months of oral or parenteral methotrexate (at a dose of 10-20 mg/m2 weekly or at the maximum tolerated dose) in combination with either oral corticosteroids (prednisone 0.25 mg/kg or at the maximum tolerated dose) or a full trial of serial intra-articular corticosteroid injections; and 5 Both: 5.1 Either: 5.1.1 Patient has persistent symptoms of poorly-controlled and active disease in at least 20 swollen, tender joints; or 5.1.2 Patient has persistent symptoms of poorly-controlled and active disease in at least four joints from the following: wrist, elbow, knee, ankle, shoulder, cervical spine, hip; and 5.2 Physician’s global assessment indicating severe disease. Initial application — (rheumatoid arthritis) only from a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has had an initial Special Authority approval for adalimumab for rheumatoid arthritis; and 1.2 Either: 1.2.1 The patient has experienced intolerable side effects from adalimumab; or continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

103

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 1.2.2 The patient has received insufﬁcient beneﬁt from adalimumab to meet the renewal criteria for adalimumab for rheumatoid arthritis; or 2 All of the following: 2.1 Patient has had severe and active erosive rheumatoid arthritis for six months duration or longer; and 2.2 Treatment is to be used as an adjunct to methotrexate therapy or monotherapy where use of methotrexate is limited by toxicity or intolerance; and 2.3 Patient has tried and not responded to at least three months of oral or parenteral methotrexate at a dose of at least 20 mg weekly or a maximum tolerated dose; and 2.4 Patient has tried and not responded to at least three months of oral or parenteral methotrexate in combination with sulphasalazine and hydroxychloroquine sulphate (at maximum tolerated doses); and 2.5 Any of the following: 2.5.1 Patient has tried and not responded to at least three months of oral or parenteral methotrexate in combination with the maximum tolerated dose of cyclosporin; or 2.5.2 Patient has tried and not responded to at least three months of oral or parenteral methotrexate in combination with intramuscular gold; or 2.5.3 Patient has tried and not responded to at least three months of therapy at the maximum tolerated dose of leﬂunomide alone or in combination with oral or parenteral methotrexate; and 2.6 Either: 2.6.1 Patient has persistent symptoms of poorly controlled and active disease in at least 20 swollen, tender joints; or 2.6.2 Patient has persistent symptoms of poorly controlled and active disease in at least four joints from the following: wrist, elbow, knee, ankle, and either shoulder or hip; and 2.7 Either: 2.7.1 Patient has a C-reactive protein level greater than 15 mg/L measured no more than one month prior to the date of this application; or 2.7.2 C-reactive protein levels not measured as patient is currently receiving prednisone therapy at a dose of greater than 5 mg per day and has done so for more than three months. Initial application — (severe chronic plaque psoriasis) only from a dermatologist. Approvals valid for 4 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has had an initial Special Authority approval for adalimumab for severe chronic plaque psoriasis; and 1.2 Either: 1.2.1 The patient has experienced intolerable side effects from adalimumab; or 1.2.2 The patient has received insufﬁcient beneﬁt from adalimumab to meet the renewal criteria for adalimumab for severe chronic plaque psoriasis; or 2 All of the following: 2.1 Either: 2.1.1 Patient has "whole body" severe chronic plaque psoriasis with a Psoriasis Area and Severity Index (PASI) score of greater than 15, where lesions have been present for at least 6 months from the time of initial diagnosis; or 2.1.2 Patient has severe chronic plaque psoriasis of the face, or palm of a hand or sole of a foot, where the plaque or plaques have been present for at least 6 months from the time of initial diagnosis; and 2.2 Patient has tried, but had an inadequate response (see Note) to, or has experienced intolerable side effects from, at least three of the following (at maximum tolerated doses unless contraindicated): phototherapy, methotrexate, cyclosporin, or acitretin; and 2.3 A PASI assessment has been completed for at least the most recent prior treatment course (but preferably all prior treatment courses), preferably while still on treatment but no longer than 1 month following cessation of each prior treatment course; and 2.4 The most recent PASI assessment is no more than 1 month old at the time of application. continued. . .

104

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . Note: "Inadequate response" is deﬁned as: for whole body severe chronic plaque psoriasis, a PASI score of greater than 15, as assessed preferably while still on treatment but no longer than 1 month following cessation of the most recent prior treatment; for severe chronic plaque psoriasis of the face, hand or foot, at least 2 of the 3 PASI symptom subscores for erythema, thickness and scaling are rated as severe or very severe, and the skin area affected is 30% or more of the face, palm of a hand or sole of a foot, as assessed preferably while still on treatment but no longer than 1 month following cessation of the most recent prior treatment. Initial application — (ankylosing spondylitis) only from a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has had an initial Special Authority approval for adalimumab for ankylosing spondylitis; and 1.2 Either: 1.2.1 The patient has experienced intolerable side effects from adalimumab; or 1.2.2 The patient has received insufﬁcient beneﬁt from adalimumab to meet the renewal criteria for adalimumab for ankylosing spondylitis; or 2 All of the following: 2.1 Patient has a conﬁrmed diagnosis of ankylosing spondylitis present for more than six months; and 2.2 Patient has low back pain and stiffness that is relieved by exercise but not by rest; and 2.3 Patient has bilateral sacroiliitis demonstrated by plain radiographs, CT or MRI scan; and 2.4 Patient’s ankylosing spondylitis has not responded adequately to treatment with two or more non-steroidal antiinﬂammatory drugs (NSAIDs), in combination with anti-ulcer therapy if indicated, while patient was undergoing at least 3 months of an exercise regime supervised by a physiotherapist; and 2.5 Either: 2.5.1 Patient has limitation of motion of the lumbar spine in the sagittal and the frontal planes as determined by the following Bath Ankylosing Spondylitis Metrology Index (BASMI) measures: a modiﬁed Schober’s test of less than or equal to 4 cm and lumbar side ﬂexion measurement of less than or equal to 10 cm (mean of left and right); or 2.5.2 Patient has limitation of chest expansion by at least 2.5 cm below the average normal values corrected for age and gender (see Notes); and 2.6 A Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) of at least 6 on a 0-10 scale. Notes: The BASDAI must have been determined at the completion of the 3 month exercise trial, but prior to ceasing NSAID treatment. The BASDAI measure must be no more than 1 month old at the time of initial application. Average normal chest expansion corrected for age and gender: 18-24 years - Male: 7.0 cm; Female: 5.5 cm 25-34 years - Male: 7.5 cm; Female: 5.5 cm 35-44 years - Male: 6.5 cm; Female: 4.5 cm 45-54 years - Male: 6.0 cm; Female: 5.0 cm 55-64 years - Male: 5.5 cm; Female: 4.0 cm 65-74 years - Male: 4.0 cm; Female: 4.0 cm 75+ years - Male: 3.0 cm; Female: 2.5 cm Initial application — (psoriatic arthritis) only from a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has had an initial Special Authority approval for adalimumab for psoriatic arthritis; and 1.2 Either: 1.2.1 The patient has experienced intolerable side effects from adalimumab; or 1.2.2 The patient has received insufﬁcient beneﬁt from adalimumab to meet the renewal criteria for adalimumab for psoriatic arthritis; or continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

105

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 2 All of the following: 2.1 Patient has had severe active psoriatic arthritis for six months duration or longer; and 2.2 Patient has tried and not responded to at least three months of oral or parenteral methotrexate at a dose of at least 20 mg weekly or a maximum tolerated dose; and 2.3 Patient has tried and not responded to at least three months of sulphasalazine at a dose of at least 2 g per day or leﬂunomide at a dose of up to 20 mg daily (or maximum tolerated doses); and 2.4 Either: 2.4.1 Patient has persistent symptoms of poorly controlled and active disease in at least 15 swollen, tender joints; or 2.4.2 Patient has persistent symptoms of poorly controlled and active disease in at least four joints from the following: wrist, elbow, knee, ankle, and either shoulder or hip; and 2.5 Any of the following: 2.5.1 Patient has a C-reactive protein level greater than 15 mg/L measured no more than one month prior to the date of this application; or 2.5.2 Patient has an elevated erythrocyte sedimentation rate (ESR) greater than 25 mm per hour; or 2.5.3 ESR and CRP not measured as patient is currently receiving prednisone therapy at a dose of greater than 5 mg per day and has done so for more than three months. Renewal — (juvenile idiopathic arthritis) only from a named specialist, rheumatologist or Practitioner on the recommendation of a named specialist or rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Either: 1.1 Applicant is a named specialist or rheumatologist; or 1.2 Applicant is a Practitioner and conﬁrms that a named specialist or rheumatologist has provided a letter, email or fax recommending that the patient continues with etanercept treatment; and 2 Subsidised as an adjunct to methotrexate therapy or monotherapy where use of methotrexate is limited by toxicity or intolerance; and 3 Either: 3.1 Following 3 to 4 months’ initial treatment, the patient has at least a 50% decrease in active joint count and an improvement in physician’s global assessment from baseline; or 3.2 On subsequent reapplications, the patient demonstrates at least a continuing 30% improvement in active joint count and continued improvement in physician’s global assessment from baseline. Renewal — (rheumatoid arthritis) only from a rheumatologist or Practitioner on the recommendation of a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Either: 1.1 Applicant is a rheumatologist; or 1.2 Applicant is a Practitioner and conﬁrms that a rheumatologist has provided a letter, email or fax recommending that the patient continues with etanercept treatment; and 2 Treatment is to be used as an adjunct to methotrexate therapy or monotherapy where use of methotrexate is limited by toxicity or intolerance; and 3 Either: 3.1 Following 3 to 4 months’ initial treatment, the patient has at least a 50% decrease in active joint count from baseline and a clinically signiﬁcant response to treatment in the opinion of the physician; or 3.2 On subsequent reapplications, the patient demonstrates at least a continuing 30% improvement in active joint count from baseline and a clinically signiﬁcant response to treatment in the opinion of the physician; and 4 Etanercept to be administered at doses no greater than 50 mg every 7 days. Renewal — (severe chronic plaque psoriasis) only from a dermatologist or Practitioner on the recommendation of a dermatologist. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Either: continued. . .

106

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 1.1 Applicant is a dermatologist; or 1.2 Applicant is a Practitioner and conﬁrms that a dermatologist has provided a letter, email or fax recommending that the patient continues with etanercept treatment; and 2 Either: 2.1 Both: 2.1.1 Patient had "whole body" severe chronic plaque psoriasis at the start of treatment; and 2.1.2 Following each prior etanercept treatment course the patient has a PASI score which is reduced by 75% or more, or is sustained at this level, when compared with the pre-treatment baseline value; or 2.2 Both: 2.2.1 Patient had severe chronic plaque psoriasis of the face, or palm of a hand or sole of a foot at the start of treatment; and 2.2.2 Either: 2.2.2.1 Following each prior etanercept treatment course the patient has a reduction in the PASI symptom subscores for all 3 of erythema, thickness and scaling, to slight or better, or sustained at this level, as compared to the treatment course baseline values; or 2.2.2.2 Following each prior etanercept treatment course the patient has a reduction of 75% or more in the skin area affected, or sustained at this level, as compared to the pre-treatment baseline value; and 3 Etanercept to be administered at doses no greater than 50 mg every 7 days. Note: A treatment course is deﬁned as a minimum of 12 weeks of etanercept treatment Renewal — (ankylosing spondylitis) only from a rheumatologist or Practitioner on the recommendation of a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Either: 1.1 Applicant is a rheumatologist; or 1.2 Applicant is a Practitioner and conﬁrms that a rheumatologist has provided a letter, email or fax recommending that the patient continues with etanercept treatment; and 2 Following 12 weeks of etanercept treatment, BASDAI has improved by 4 or more points from pre-treatment baseline on a 10 point scale, or by 50%, whichever is less; and 3 Physician considers that the patient has beneﬁted from treatment and that continued treatment is appropriate; and 4 Etanercept to be administered at doses no greater than 50 mg every 7 days. Renewal — (psoriatic arthritis) only from a rheumatologist or Practitioner on the recommendation of a rheumatologist. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Either: 1.1 Applicant is a rheumatologist; or 1.2 Applicant is a Practitioner and conﬁrms that a rheumatologist has provided a letter, email or fax recommending that the patient continues with etanercept treatment; and 2 Either: 2.1 Following 3 to 4 months’ initial treatment, the patient has at least a 50% decrease in active joint count from baseline and a clinically signiﬁcant response to treatment in the opinion of the physician; or 2.2 The patient demonstrates at least a continuing 30% improvement in active joint count from baseline and a clinically signiﬁcant response to prior etanercept treatment in the opinion of the treating physician; and 3 Etanercept to be administered at doses no greater than 50 mg every 7 days.

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

107

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Drugs Affecting Bone Metabolism Alendronate for Osteoporosis

¾SA1039 Special Authority for Subsidy Initial application — (Underlying cause – Osteoporosis) from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Any of the following: 1 History of one signiﬁcant osteoporotic fracture demonstrated radiologically and documented bone mineral density (BMD) ≥ 2.5 standard deviations below the mean normal value in young adults (i.e. T-Score ≤ -2.5) (see Note); or 2 History of one signiﬁcant osteoporotic fracture demonstrated radiologically, and either the patient is elderly, or densitometry scanning cannot be performed because of major logistical, technical or pathophysiological reasons. It is unlikely that this provision would apply to many patients under 75 years of age; or 3 History of two signiﬁcant osteoporotic fractures demonstrated radiologically; or 4 Documented T-Score ≤ -3.0 (see Note); or 5 A 10-year risk of hip fracture ≥ 3%, calculated using a published risk assessment algorithm (e.g. FRAX or Garvan) which incorporates BMD measurements (see Note); or 6 Patient has had a Special Authority approval for zoledronic acid (Underlying cause - Osteoporosis) or raloxifene. Initial application — (Underlying cause – glucocorticosteroid therapy) from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The patient is receiving systemic glucocorticosteriod therapy (≥ 5 mg per day prednisone equivalents) and has already received or is expected to receive therapy for at least three months; and 2 Any of the following: 2.1 The patient has documented BMD ≥ 1.5 standard deviations below the mean normal value in young adults (i.e. T-Score ≤ -1.5) (see Note); or 2.2 The patient has a history of one signiﬁcant osteoporotic fracture demonstrated radiologically; or 2.3 The patient has had a Special Authority approval for zoledronic acid (Underlying cause - glucocorticosteroid therapy) or raloxifene. Renewal — (Underlying cause was, and remains, glucocorticosteroid therapy) from any relevant practitioner. Approvals valid for 1 year where the patient is continuing systemic glucocorticosteriod therapy (≥ 5 mg per day prednisone equivalents). Renewal — (Underlying cause was glucocorticosteroid therapy but patient now meets the ‘Underlying cause - osteoporosis’ criteria) from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Any of the following: 1 History of one signiﬁcant osteoporotic fracture demonstrated radiologically and documented bone mineral density (BMD) ≥ 2.5 standard deviations below the mean normal value in young adults (i.e. T-Score ≤ -2.5) (see Note); or 2 History of one signiﬁcant osteoporotic fracture demonstrated radiologically, and either the patient is elderly, or densitometry scanning cannot be performed because of major logistical, technical or pathophysiological reasons. It is unlikely that this provision would apply to many patients under 75 years of age; or 3 History of two signiﬁcant osteoporotic fractures demonstrated radiologically; or 4 Documented T-Score ≤ -3.0 (see Note); or 5 A 10-year risk of hip fracture ≥ 3%, calculated using a published risk assessment algorithm (e.g. FRAX or Garvan) which incorporates BMD measurements (see Note); or 6 Patient has had a Special Authority approval for zoledronic acid (Underlying cause was glucocorticosteroid therapy but patient now meets the ‘Underlying cause - Osteoporosis’ criteria) or raloxifene. Notes: a) BMD (including BMD used to derive T-Score) must be measured using dual-energy x-ray absorptiometry (DXA). Quantitative ultrasound and quantitative computed tomography (QCT) are not acceptable. continued. . .

108

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . b) Evidence used by National Institute for Health and Clinical Excellence (NICE) guidance indicates that patients aged 75 years and over who have a history of signiﬁcant osteoporotic fracture demonstrated radiologically are very likely to have a T-Score ≤ -2.5 and, therefore, do not require BMD measurement for treatment with bisphosphonates. c) Osteoporotic fractures are the incident events for severe (established) osteoporosis, and can be deﬁned using the WHO deﬁnitions of osteoporosis and fragility fracture. The WHO deﬁnes severe (established) osteoporosis as a T-score below -2.5 with one or more associated fragility fractures. Fragility fractures are fractures that occur as a result of mechanical forces that would not ordinarily cause fracture (minimal trauma). The WHO has quantiﬁed this as forces equivalent to a fall from a standing height or less. d) In line with the Australian guidelines for funding alendronate, a vertebral fracture is deﬁned as a 20% or greater reduction in height of the anterior or mid portion of a vertebral body relative to the posterior height of that body, or a 20% or greater reduction in any of these heights compared to the vertebral body above or below the affected vertebral body. ALENDRONATE SODIUM – Special Authority see SA1039 on the preceding page – Retail pharmacy Tab 70 mg .........................................................................................22.90 4 Fosamax ALENDRONATE SODIUM WITH CHOLECALCIFEROL – Special Authority see SA1039 on the preceding page – Retail pharmacy Tab 70 mg with cholecalciferol 5,600 iu ............................................22.90 4 Fosamax Plus

Alendronate for Paget’s Disease

¾SA0949 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 6 months for applications meeting the following criteria: Both: 1 Paget’s disease; and 2 Any of the following: 2.1 Bone or articular pain; or 2.2 Bone deformity; or 2.3 Bone, articular or neurological complications; or 2.4 Asymptomatic disease, but risk of complications due to site (base of skull, spine, long bones of lower limbs); or 2.5 Preparation for orthopaedic surgery. Renewal from any relevant practitioner. Approvals valid for 6 months where the treatment remains appropriate and the patient is beneﬁting from treatment. ALENDRONATE SODIUM – Special Authority see SA0949 above – Retail pharmacy Tab 40 mg .......................................................................................133.00 30 Fosamax

Other Treatments

CALCITONIN F Inj 100 iu per ml, 1 ml .....................................................................110.00 5

Miacalcic

ETIDRONATE DISODIUM – See prescribing guideline below F Tab 200 mg .......................................................................................23.95 100 Arrow-Etidronate Prescribing Guidelines Etidronate for osteoporosis should be prescribed for 14 days (400 mg in the morning) and repeated every three months. It should not be taken at the same time of the day as any calcium supplementation (minimum dose – 500 mg per day of elemental calcium). Etidronate should be taken at least 2 hours before or after any food or ﬂuid, except water. PAMIDRONATE DISODIUM Inj 3 mg per ml, 5 ml .........................................................................18.75 1 Pamisol Inj 3 mg per ml, 10 ml .......................................................................37.50 1 Pamisol Inj 6 mg per ml, 10 ml .......................................................................75.00 1 Pamisol Inj 9 mg per ml, 10 ml .....................................................................112.50 1 Pamisol RALOXIFENE HYDROCHLORIDE – Special Authority see SA1138 on the next page – Retail pharmacy Tab 60 mg .........................................................................................53.76 28 Evista

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

109

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA1138 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Any of the following: 1 History of one signiﬁcant osteoporotic fracture demonstrated radiologically and documented bone mineral density (BMD) ≥ 2.5 standard deviations below the mean normal value in young adults (i.e. T-Score ≤ -2.5) (see Notes); or 2 History of one signiﬁcant osteoporotic fracture demonstrated radiologically, and either the patient is elderly, or densitometry scanning cannot be performed because of major logistical, technical or pathophysiological reasons. It is unlikely that this provision would apply to many patients under 75 years of age; or 3 History of two signiﬁcant osteoporotic fractures demonstrated radiologically; or 4 Documented T-Score ≤ -3.0 (see Notes); or 5 A 10-year risk of hip fracture ≥ 3%, calculated using a published risk assessment algorithm (e.g. FRAX or Garvan) which incorporates BMD measurements (see Notes); or 6 Patient has had a prior Special Authority approval for zoledronic acid (Underlying cause - Osteoporosis) or alendronate (Underlying cause - Osteoporosis). Notes: a) BMD (including BMD used to derive T-Score) must be measured using dual-energy x-ray absorptiometry (DXA). Quantitative ultrasound and quantitative computed tomography (QCT) are not acceptable. b) Evidence used by the UK National Institute for Health and Clinical Excellence (NICE) in developing its guidance indicates that patients aged 75 years and over who have a history of signiﬁcant osteoporotic fracture demonstrated radiologically are very likely to have a T-Score ≤ -2.5 and, therefore, do not require BMD measurement for raloxifene funding. c) Osteoporotic fractures are the incident events for severe (established) osteoporosis, and can be deﬁned using the WHO deﬁnitions of osteoporosis and fragility fracture. The WHO deﬁnes severe (established) osteoporosis as a T-score below -2.5 with one or more associated fragility fractures. Fragility fractures are fractures that occur as a result of mechanical forces that would not ordinarily cause fracture (minimal trauma). The WHO has quantiﬁed this as forces equivalent to a fall from a standing height or less. d) A vertebral fracture is deﬁned as a 20% or greater reduction in height of the anterior or mid portion of a vertebral body relative to the posterior height of that body, or a 20% or greater reduction in any of these heights compared to the vertebral body above or below the affected vertebral body. TERIPARATIDE – Special Authority see SA1139 below – Retail pharmacy Inj 250 µg per ml, 2.4 ml .................................................................490.00 1 Forteo ¾SA1139 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 18 months for applications meeting the following criteria: All of the following: 1 The patient has severe, established osteoporosis; and 2 The patient has a documented T-score less than or equal to -3.0 (see Notes); and 3 The patient has had two or more fractures due to minimal trauma; and 4 The patient has experienced at least one symptomatic new fracture after at least 12 months’ continuous therapy with a funded antiresorptive agent at adequate doses (see Notes). Notes: a) The bone mineral density (BMD) measurement used to derive the T-score must be made using dual-energy x-ray absorptiometry (DXA). Quantitative ultrasound and quantitative computed tomography (QCT) are not acceptable b) Antiresorptive agents and their adequate doses for the purposes of this Special Authority are deﬁned as: alendronate sodium tab 70 mg or tab 70 mg with cholecalciferol 5,600 iu once weekly; raloxifene hydrochloride tab 60 mg once daily; zoledronic acid 5 mg per year. If an intolerance of a severity necessitating permanent treatment withdrawal develops during the use of one antiresorptive agent, an alternate antiresorptive agent must be trialled so that the patient achieves the minimum requirement of 12 months’ continuous therapy. c) A vertebral fracture is deﬁned as a 20% or greater reduction in height of the anterior or mid portion of a vertebral body relative to the posterior height of that body, or a 20% or greater reduction in any of these heights compared to the vertebral body above or below the affected vertebral body. d) A maximum of 18 months of treatment (18 cartridges) will be subsidised.

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

110

fully subsidised [HP4] refer page 9

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

ZOLEDRONIC ACID – Special Authority see SA1035 below – Retail pharmacy Soln for infusion 5 mg in 100 ml .....................................................600.00

100 ml

Aclasta

¾SA1035 Special Authority for Subsidy Initial application — (Paget’s disease) from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 Paget’s disease; and 2 Any of the following: 2.1 Bone or articular pain; or 2.2 Bone deformity; or 2.3 Bone, articular or neurological complications; or 2.4 Asymptomatic disease, but risk of complications; or 2.5 Preparation for orthopaedic surgery; and 3 The patient will not be prescribed more than one infusion in the 12-month approval period. Initial application — (Underlying cause - Osteoporosis) from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Both: 1 Any of the following: 1.1 History of one signiﬁcant osteoporotic fracture demonstrated radiologically and documented bone mineral density (BMD) ≥ 2.5 standard deviations below the mean normal value in young adults (i.e. T-Score ≤ -2.5) (see Note); or 1.2 History of one signiﬁcant osteoporotic fracture demonstrated radiologically, and either the patient is elderly, or densitometry scanning cannot be performed because of major logistical, technical or pathophysiological reasons. It is unlikely that this provision would apply to many patients under 75 years of age; or 1.3 History of two signiﬁcant osteoporotic fractures demonstrated radiologically; or 1.4 Documented T-Score ≤ -3.0 (see Note); or 1.5 A 10-year risk of hip fracture ≥ 3%, calculated using a published risk assessment algorithm (e.g. FRAX or Garvan) which incorporates BMD measurements (see Note); or 1.6 Patient has had a Special Authority approval for alendronate (Underlying cause - Osteoporosis) or raloxifene; and 2 The patient will not be prescribed more than one infusion in a 12-month period. Initial application — (Underlying cause - glucocorticosteroid therapy) from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 The patient is receiving systemic glucocorticosteriod therapy (≥ 5 mg per day prednisone equivalents) and has already received or is expected to receive therapy for at least three months; and 2 Any of the following: 2.1 The patient has documented BMD ≥ 1.5 standard deviations below the mean normal value in young adults (i.e. T-Score ≤ -1.5) (see Note); or 2.2 The patient has a history of one signiﬁcant osteoporotic fracture demonstrated radiologically; or 2.3 The patient has had a Special Authority approval for alendronate (Underlying cause - glucocorticosteroid therapy) or raloxifene; and 3 The patient will not be prescribed more than one infusion in the 12-month approval period. Renewal — (Paget’s disease) from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 Any of the following: 1.1 The patient has relapsed (based on increases in serum alkaline phosphatase); or 1.2 The patient’s serum alkaline phosphatase has not normalised following previous treatment with zoledronic acid; or 1.3 Symptomatic disease (prescriber determined); and continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

111

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 2 The patient will not be prescribed more than one infusion in the 12-month approval period. The patient may not have had an approval in the past 12 months. Renewal — (Underlying cause was, and remains, glucocorticosteroid therapy) from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The patient is continuing systemic glucocorticosteriod therapy (≥ 5 mg per day prednisone equivalents); and 2 The patient will not be prescribed more than one infusion in the 12-month approval period. The patient may not have had an approval in the past 12 months. Renewal — (Underlying cause was glucocorticosteroid therapy but patient now meets the ‘Underlying cause - osteoporosis’ criteria) from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Both: 1 Any of the following: 1.1 History of one signiﬁcant osteoporotic fracture demonstrated radiologically and documented bone mineral density (BMD) ≥ 2.5 standard deviations below the mean normal value in young adults (i.e. T-Score ≤ -2.5) (see Note); or 1.2 History of one signiﬁcant osteoporotic fracture demonstrated radiologically, and either the patient is elderly, or densitometry scanning cannot be performed because of major logistical, technical or pathophysiological reasons. It is unlikely that this provision would apply to many patients under 75 years of age; or 1.3 History of two signiﬁcant osteoporotic fractures demonstrated radiologically; or 1.4 Documented T-Score ≤ -3.0 (see Note); or 1.5 A 10-year risk of hip fracture ≥ 3%, calculated using a published risk assessment algorithm (e.g. FRAX or Garvan) which incorporates BMD measurements (see Note); or 1.6 Patient has had a Special Authority approval for alendronate (Underlying cause was glucocorticosteroid therapy but patient now meets the ‘Underlying cause - Osteoporosis’ criteria) or raloxifene; and 2 The patient will not be prescribed more than one infusion in a 12-month period. Notes: a) BMD (including BMD used to derive T-Score) must be measured using dual-energy x-ray absorptiometry (DXA). Quantitative ultrasound and quantitative computed tomography (QCT) are not acceptable. b) Evidence used by National Institute for Health and Clinical Excellence (NICE) guidance indicates that patients aged 75 years and over who have a history of signiﬁcant osteoporotic fracture demonstrated radiologically are very likely to have a T-Score ≤ -2.5 and, therefore, do not require BMD measurement for treatment with bisphosphonates. c) Osteoporotic fractures are the incident events for severe (established) osteoporosis and can be deﬁned using the WHO deﬁnitions of osteoporosis and fragility fracture. The WHO deﬁnes severe (established) osteoporosis as a T-score below -2.5 with one or more associated fragility fractures. Fragility fractures are fractures that occur as a result of mechanical forces that would not ordinarily cause fracture (minimal trauma). The WHO has quantiﬁed this as forces equivalent to a fall from a standing height or less. d) A vertebral fracture is deﬁned as a 20% or greater reduction in height of the anterior or mid portion of a vertebral body relative to the posterior height of that body, or a 20% or greater reduction in any of these heights compared to the vertebral body above or below the affected vertebral body.

112

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

MUSCULOSKELETAL SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Hyperuricaemia and Antigout

ALLOPURINOL F Tab 100 mg ........................................................................................3.98 (5.44) 15.90 F Tab 300 mg – For allopurinol oral liquid formulation refer, page 172 ......................................................................................4.03 20.15 3.35 (4.03) 16.75 (Apo-Allopurinol Tab 100 mg to be delisted 1 March 2012) (Apo-Allopurinol S29 S29 Tab 300 mg to be delisted 1 March 2012) (Apo-Allopurinol Tab 300 mg to be delisted 1 March 2012) COLCHICINE F Tab 500 µg ..........................................................................................9.60 PROBENECID F Tab 500 mg .......................................................................................55.00 100 100 250 Apo-Allopurinol 1,000 100 500 100 Apo-Allopurinol 500

Apo-Allopurinol Apo-Allopurinol

S29 S29

Apo-Allopurinol

S29 S29

Apo-Allopurinol

Colgout Probenecid-AFT

Muscle Relaxants

BACLOFEN F Tab 10 mg – For baclofen oral liquid formulation refer, page 172 ...............................................................................................4.75 DANTROLENE SODIUM F Cap 25 mg ........................................................................................32.96 (65.00) F Cap 50 mg ........................................................................................51.70 (77.00) ORPHENADRINE CITRATE Tab 100 mg .......................................................................................18.54 QUININE SULPHATE F Tab 200 mg ......................................................................................15.95 (17.20) ‡ Safety cap for extemporaneously compounded oral liquid preparations. F Tab 300 mg .......................................................................................54.06 ‡ Safety cap for extemporaneously compounded oral liquid preparations. (Q 200 Tab 200 mg to be delisted 1 June 2012)

100 100

Pacifen

Dantrium 100 Dantrium 100 250 Q 200 500

Norﬂex

Q 300

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

113

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Agents for Parkinsonism and Related Disorders Dopamine Agonists and Related Agents

AMANTADINE HYDROCHLORIDE L Cap 100 mg ......................................................................................38.24 APOMORPHINE HYDROCHLORIDE L Inj 10 mg per ml, 2 ml .....................................................................110.00 BROMOCRIPTINE MESYLATE F Tab 2.5 mg ........................................................................................32.08 F Cap 5 mg ..........................................................................................60.43 ENTACAPONE L Tab 200 mg .....................................................................................116.00 LEVODOPA WITH BENSERAZIDE F Tab dispersible 50 mg with benserazide 12.5 mg .............................10.00 F F F F Cap 50 mg with benserazide 12.5 mg ................................................8.00 Cap 100 mg with benserazide 25 mg ...............................................12.50 Cap long-acting 100 mg with benserazide 25 mg ............................17.00 Cap 200 mg with benserazide 50 mg ...............................................25.00 60 5 100 100 100 100 100 100 100 100

Symmetrel Apomine Apo-Bromocriptine Apo-Bromocriptine Comtan Madopar

Dispersible

Madopar 62.5 Madopar 125 Madopar HBS Madopar 250

LEVODOPA WITH CARBIDOPA F Tab 100 mg with carbidopa 25 mg – For levodopa with carbidopa oral liquid formulation refer, page 172 ............................10.00 20.00 F Tab long-acting 200 mg with carbidopa 50 mg .................................47.50 F Tab 250 mg with carbidopa 25 mg ....................................................40.00 LISURIDE HYDROGEN MALEATE L Tab 200 µg ........................................................................................27.50 PERGOLIDE L Tab 0.25 mg ......................................................................................48.00 L Tab 1 mg .........................................................................................170.00 ROPINIROLE HYDROCHLORIDE L Tab 0.25 mg ........................................................................................6.20 L Tab 1 mg ...........................................................................................15.95 L Tab 2 mg ...........................................................................................24.95 L Tab 5 mg ...........................................................................................38.00 SELEGILINE HYDROCHLORIDE F Tab 5 mg ...........................................................................................16.06

50 100 100 100 30 100 100 84 84 84 84 100

Sindopa Sinemet Sinemet CR Sinemet Dopergin Permax Permax Ropin Ropin Ropin Ropin Apo-Selegiline Apo-Selegiline

S29 S29

(Apo-Selegiline S29

S29

Tab 5 mg to be delisted 1 March 2012) 100

TOLCAPONE L Tab 100 mg .....................................................................................126.20

Tasmar

114

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Anticholinergics

BENZTROPINE MESYLATE Tab 2 mg .............................................................................................7.99 Inj 1 mg per ml, 2 ml .........................................................................36.35 a) Up to 5 inj available on a PSO b) Only on a PSO ORPHENADRINE HYDROCHLORIDE Tab 50 mg .........................................................................................31.93 PROCYCLIDINE HYDROCHLORIDE Tab 5 mg .............................................................................................7.40 60 5

Benztrop Cogentin

250 100

Disipal Kemadrin

Agents for Essential Tremor, Chorea and Related Disorders

TETRABENAZINE Tab 25 mg .......................................................................................243.00 112

Xenazine 25

Anaesthetics Local

LIGNOCAINE Gel 2%, 10 ml urethral syringe – Subsidy by endorsement...............43.26 10 Pﬁzer a) Up to 5 each available on a PSO b) Subsidised only if prescribed for urethral or cervical administration and the prescription is endorsed accordingly. LIGNOCAINE HYDROCHLORIDE Viscous soln 2% ...............................................................................55.00 200 ml Xylocaine Viscous Inj 1%, 5 ml – Up to 5 inj available on a PSO...................................35.00 50 Xylocaine Inj 2%, 5 ml – Up to 5 inj available on a PSO...................................23.00 50 Xylocaine Inj 1%, 20 ml – Up to 5 inj available on a PSO.................................20.00 5 Xylocaine Inj 2%, 20 ml – Up to 5 inj available on a PSO.................................15.00 5 Xylocaine LIGNOCAINE WITH CHLORHEXIDINE Gel 2% with chlorhexidine 0.05%, 10 ml urethral syringes – Subsidy by endorsement ............................................................ 43.26 10 Pﬁzer a) Up to 5 each available on a PSO b) Subsidised only if prescribed for urethral or cervical administration and the prescription is endorsed accordingly. LIGNOCAINE WITH PRILOCAINE – Special Authority see SA0906 below – Retail pharmacy Crm 2.5% with prilocaine 2.5% ........................................................45.00 30 g OP EMLA Crm 2.5% with prilocaine 2.5% (5 g tubes) ......................................45.00 5 EMLA ¾SA0906 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 2 years where the patient is a child with a chronic medical condition requiring frequent injections or venepuncture. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment.

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

115

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Analgesics

For Anti-inﬂammatory NSAIDS refer to MUSCULOSKELETAL, page 97

Non-opioid Analgesics

ASPIRIN F Tab EC 300 mg ...................................................................................2.00 (8.10) F Tab dispersible 300 mg – Up to 30 tab available on a PSO ...............2.00 NEFOPAM HYDROCHLORIDE Tab 30 mg .........................................................................................23.40 PARACETAMOL F Tab 500 mg – Up to 30 tab available on a PSO..................................9.38 9.60 F‡ Oral liq 120 mg per 5 ml .....................................................................2.21 4.42 a) Up to 200 ml available on a PSO b) Not in combination F‡ Oral liq 250 mg per 5 ml .....................................................................6.70 a) Up to 100 ml available on a PSO b) Not in combination F Suppos 125 mg ..................................................................................7.49 F Suppos 250 mg ................................................................................14.40 F Suppos 500 mg ................................................................................20.50 (Paracare Junior Oral liq 120 mg per 5 ml to be delisted 1 March 2012) TRAMADOL HYDROCHLORIDE Cap 50 mg ..........................................................................................4.95 100 Aspec 300 100 90 1,000 500 ml 1,000 ml

Ethics Aspirin Acupan Parafast Pharmacare Ethics Paracetamol Paracare Junior Paracare Double

Strength

1,000 ml

20 20 50

Panadol Panadol Paracare

100

Arrow-Tramadol

Opioid Analgesics

CODEINE PHOSPHATE Tab 15 mg ...........................................................................................5.39 Tab 30 mg ...........................................................................................8.25 Tab 60 mg .........................................................................................17.76 DIHYDROCODEINE TARTRATE Tab long-acting 60 mg ......................................................................27.27 FENTANYL a) Only on a controlled drug form b) No patient co-payment payable Transdermal patch 12.5 µg per hour ..................................................8.90 Transdermal patch 25 µg per hour .....................................................9.15 Transdermal patch 50 µg per hour ...................................................11.50 Transdermal patch 75 µg per hour ...................................................13.60 Transdermal patch 100 µg per hour .................................................14.50 100 100 100 60

PSM PSM PSM DHC Continus

5 5 5 5 5

Mylan Fentanyl

Patch

Mylan Fentanyl

Patch

Mylan Fentanyl

Patch

Mylan Fentanyl

Patch

Mylan Fentanyl

Patch

116

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

FENTANYL CITRATE a) Only on a controlled drug form b) No patient co-payment payable Inj 50 µg per ml, 2 ml ..........................................................................6.43 Inj 50 µg per ml, 10 ml ......................................................................16.81

10 10

Boucher and Muir Boucher and Muir

METHADONE HYDROCHLORIDE a) Only on a controlled drug form b) No patient co-payment payable c) Extemporaneously compounded methadone will only be reimbursed at the rate of the cheapest form available (methadone powder, not methadone tablets). d) For methadone hydrochloride oral liquid refer, page 175 Tab 5 mg .............................................................................................1.85 10 Methatabs ‡ Oral liq 2 mg per ml ............................................................................5.95 200 ml Biodone ‡ Oral liq 5 mg per ml ............................................................................5.55 200 ml Biodone Forte ‡ Oral liq 10 mg per ml ..........................................................................8.95 200 ml Biodone Extra Forte Inj 10 mg per ml, 1 ml .......................................................................61.00 10 AFT MORPHINE HYDROCHLORIDE a) Only on a controlled drug form b) No patient co-payment payable ‡ Oral liq 1 mg per ml ............................................................................8.84 ‡ Oral liq 2 mg per ml ..........................................................................11.62 ‡ Oral liq 5 mg per ml ..........................................................................14.65 ‡ Oral liq 10 mg per ml ........................................................................21.55 MORPHINE SULPHATE a) Only on a controlled drug form b) No patient co-payment payable Tab immediate-release 10 mg ............................................................2.80 Tab long-acting 10 mg ........................................................................1.98 Tab immediate-release 20 mg ............................................................5.52 Tab long-acting 30 mg ........................................................................3.15 Tab long-acting 60 mg ........................................................................7.20 Tab long-acting 100 mg ......................................................................7.85 Cap long-acting 10 mg .......................................................................2.22 Cap long-acting 30 mg .......................................................................3.20 Cap long-acting 60 mg .......................................................................6.90 Cap long-acting 100 mg .....................................................................8.05 Inj 5 mg per ml, 1 ml – Up to 5 inj available on a PSO .......................5.51 Inj 10 mg per ml, 1 ml – Up to 5 inj available on a PSO .....................4.79 Inj 15 mg per ml, 1 ml – Up to 5 inj available on a PSO .....................5.01 Inj 30 mg per ml, 1 ml – Up to 5 inj available on a PSO .....................5.30 MORPHINE TARTRATE a) Only on a controlled drug form b) No patient co-payment payable Inj 80 mg per ml, 1.5 ml ....................................................................30.00 Inj 80 mg per ml, 5 ml .......................................................................75.00

200 ml 200 ml 200 ml 200 ml

RA-Morph RA-Morph RA-Morph RA-Morph

10 10 10 10 10 10 10 10 10 10 5 5 5 5

Sevredol Arrow-Morphine LA Sevredol Arrow-Morphine LA Arrow-Morphine LA Arrow-Morphine LA m-Eslon m-Eslon m-Eslon m-Eslon DBL Morphine

Sulphate

DBL Morphine

Sulphate

DBL Morphine

Sulphate

DBL Morphine

Sulphate

5 5

Hospira Hospira

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

117

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

OXYCODONE HYDROCHLORIDE a) Only on a controlled drug form b) See prescribing guideline below c) No patient co-payment payable Tab controlled-release 5 mg ...............................................................7.51 Tab controlled-release 10 mg ...........................................................11.14 Tab controlled-release 20 mg ...........................................................18.93 Tab controlled-release 40 mg ...........................................................33.29 Tab controlled-release 80 mg ...........................................................58.03 Cap 5 mg ............................................................................................2.83 Cap 10 mg ..........................................................................................5.58 Cap 20 mg ..........................................................................................9.77 ‡ Oral liq 5 mg per 5 ml .......................................................................11.20 Inj 10 mg per ml, 1 ml .......................................................................14.40 Inj 10 mg per ml, 2 ml .......................................................................28.80

20 20 20 20 20 20 20 20 250 ml 5 5

OxyContin OxyContin OxyContin OxyContin OxyContin OxyNorm OxyNorm OxyNorm OxyNorm OxyNorm OxyNorm

Prescribing Guideline Prescribers should note that oxycodone is signiﬁcantly more expensive than long-acting morphine sulphate and clinical advice suggests that it is reasonable to consider this as a second-line agent to be used after morphine. PARACETAMOL WITH CODEINE F Tab paracetamol 500 mg with codeine phosphate 8 mg ...................2.45 100 ParaCode 2.70 Paracetamol + Codeine (Relieve) (ParaCode Tab paracetamol 500 mg with codeine phosphate 8 mg to be delisted 1 February 2012) PETHIDINE HYDROCHLORIDE a) Only on a controlled drug form b) No patient co-payment payable Tab 50 mg ...........................................................................................3.20 Tab 100 mg .........................................................................................4.20 Inj 50 mg per ml, 1 ml – Up to 5 inj available on a PSO .....................5.51 Inj 50 mg per ml, 2 ml – Up to 5 inj available on a PSO .....................5.83

10 10 5 5

PSM PSM DBL Pethidine

Hydrochloride

DBL Pethidine

Hydrochloride

Antidepressants Cyclic and Related Agents

AMITRIPTYLINE Tab 10 mg ...........................................................................................2.77 Tab 25 mg ...........................................................................................1.85 Tab 50 mg ...........................................................................................3.60 CLOMIPRAMINE HYDROCHLORIDE Tab 10 mg .........................................................................................12.60 Tab 25 mg ...........................................................................................8.68 DOTHIEPIN HYDROCHLORIDE Tab 75 mg .........................................................................................10.50 Cap 25 mg ..........................................................................................6.17 50 100 100 100 100 100 100

Amirol Amitrip Amitrip Apo-Clomipramine Apo-Clomipramine Dopress Dopress

118

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

DOXEPIN HYDROCHLORIDE Cap 10 mg ..........................................................................................5.24 Cap 25 mg ..........................................................................................5.46 Cap 50 mg ..........................................................................................7.34 IMIPRAMINE HYDROCHLORIDE Tab 10 mg ...........................................................................................5.48 Tab 25 mg ...........................................................................................8.80 MAPROTILINE HYDROCHLORIDE Tab 25 mg .........................................................................................25.06 Tab 75 mg .........................................................................................21.01

100 100 100 50 50 100 30

Anten Anten Anten Tofranil Tofranil Ludiomil Ludiomil Tolvon

MIANSERIN HYDROCHLORIDE – Special Authority see SA1048 below – Retail pharmacy Tab 30 mg .........................................................................................24.86 30

¾SA1048 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 2 years for applications meeting the following criteria: Either: 1 Both: 1.1 Depression; and 1.2 Either: 1.2.1 Co-existent bladder neck obstruction; or 1.2.2 Cardiovascular disease; or 2 Both: 2.1 The patient has a severe major depressive episode; and 2.2 Either: 2.2.1 The patient must have had a trial of two different antidepressants and was unable to tolerate the treatments or failed to respond to an adequate dose over an adequate period of time (usually at least four weeks); or 2.2.2 Both: 2.2.2.1 The patient is currently a hospital in-patient as a result of an acute depressive episode; and 2.2.2.2 The patient must have had a trial of one other antidepressant and either could not tolerate it or failed to respond to an adequate dose over an adequate period of time. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment. NORTRIPTYLINE HYDROCHLORIDE Tab 10 mg ...........................................................................................5.94 100 Norpress Tab 25 mg .........................................................................................14.44 180 Norpress

Monoamine-Oxidase Inhibitors (MAOIs) - Non Selective

PHENELZINE SULPHATE Tab 15 mg .........................................................................................95.00 TRANYLCYPROMINE SULPHATE Tab 10 mg .........................................................................................22.94 100 50

Nardil Parnate

Monoamine-Oxidase Type A Inhibitors

MOCLOBEMIDE Note: There is a signiﬁcant cost differential between moclobemide and ﬂuoxetine (moclobemide being about three times more expensive). For depressive syndromes it is therefore more cost-effective to start treatment with ﬂuoxetine ﬁrst before considering prescribing moclobemide. Tab 150 mg .......................................................................................69.23 500 Apo-Moclobemide Tab 300 mg .......................................................................................31.33 100 Apo-Moclobemide

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

119

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Selective Serotonin Reuptake Inhibitors

CITALOPRAM HYDROBROMIDE F Tab 20 mg ...........................................................................................2.34 ESCITALOPRAM Tab 10 mg ...........................................................................................2.65 Tab 20 mg ...........................................................................................4.20 84 28 28

Arrow-Citalopram Loxalate Loxalate

FLUOXETINE HYDROCHLORIDE F Tab dispersible 20 mg, scored – Subsidy by endorsement .................2.50 30 Fluox Subsidised by endorsement 1) When prescribed for a patient who cannot swallow whole tablets or capsules and the prescription is endorsed accordingly; or 2) When prescribed in a daily dose that is not a multiple of 20 mg in which case the prescription is deemed to be endorsed. Note: Tablets should be combined with capsules to facilitate incremental 10 mg doses. F Cap 20 mg ..........................................................................................2.70 84 Fluox PAROXETINE HYDROCHLORIDE Tab 20 mg ...........................................................................................2.38 SERTRALINE Tab 50 mg ...........................................................................................5.40 Tab 100 mg .........................................................................................9.60 30 90 90

Loxamine Arrow-Sertraline Arrow-Sertraline

Other Antidepressants

MIRTAZAPINE – Special Authority see SA0994 below – Retail pharmacy Tab 30 mg .........................................................................................22.00 Tab 45 mg .........................................................................................35.00 30 30

Avanza Avanza

¾SA0994 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 2 years for applications meeting the following criteria: Both: 1 The patient has a severe major depressive episode; and 2 Either: 2.1 The patient must have had a trial of two different antidepressants and was unable to tolerate the treatments or failed to respond to an adequate dose over an adequate period of time (usually at least four weeks); or 2.2 Both: 2.2.1 The patient is currently a hospital in-patient as a result of an acute depressive episode; and 2.2.2 The patient must have had a trial of one other antidepressant and either could not tolerate it or failed to respond to an adequate dose over an adequate period of time. Renewal from any relevant practitioner. Approvals valid for 2 years where the patient has a high risk of relapse (prescriber determined). VENLAFAXINE – Special Authority see SA1061 on the next page – Retail pharmacy Tab 37.5 mg ......................................................................................18.64 28 Arrow-Venlafaxine XR Tab 75 mg .........................................................................................37.27 28 Arrow-Venlafaxine XR Tab 150 mg .......................................................................................45.68 28 Arrow-Venlafaxine XR Cap 37.5 mg .....................................................................................18.64 28 Efexor XR Cap 75 mg ........................................................................................37.27 28 Efexor XR 28 Efexor XR Cap 150 mg ......................................................................................45.68

120

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA1061 Special Authority for Subsidy Initial application only from a relevant specialist or vocationally registered general practitioner. Approvals valid for 2 years for applications meeting the following criteria: Both: 1 The patient has ’treatment-resistant’ depression; and 2 Either: 2.1 The patient must have had a trial of two different antidepressants and have had an inadequate response from an adequate dose over an adequate period of time (usually at least four weeks); or 2.2 Both: 2.2.1 The patient is currently a hospital in-patient as a result of an acute depressive episode; and 2.2.2 The patient must have had a trial of one other antidepressant and have had an inadequate response from an adequate dose over an adequate period of time. Renewal from any medical practitioner. Approvals valid for 2 years where the patient has a high risk of relapse (prescriber determined).

Antiepilepsy Drugs Agents for Control of Status Epilepticus

CLONAZEPAM Inj 1 mg per ml, 1 ml .........................................................................19.00 DIAZEPAM Inj 5 mg per ml, 2 ml – Subsidy by endorsement ...............................9.24 a) Up to 5 inj available on a PSO b) Only on a PSO c) PSO must be endorsed “not for anaesthetic procedures”. Rectal tubes 5 mg – Up to 5 tube available on a PSO .....................25.05 Rectal tubes 10 mg – Up to 5 tube available on a PSO ...................30.50 PARALDEHYDE F Inj 5 ml .........................................................................................1,500.00 PHENYTOIN SODIUM F Inj 50 mg per ml, 2 ml – Up to 5 inj available on a PSO ...................69.24 F Inj 50 mg per ml, 5 ml – Up to 5 inj available on a PSO ...................77.27 5 5

Rivotril Mayne

5 5 5 5 5

Stesolid Stesolid AFT Mayne Mayne

Control of Epilepsy

CARBAMAZEPINE F Tab 200 mg .......................................................................................14.53 F Tab long-acting 200 mg ....................................................................16.98 F Tab 400 mg .......................................................................................34.58 F Tab long-acting 400 mg ....................................................................39.17 F‡ Oral liq 100 mg per 5 ml ...................................................................26.37 CLOBAZAM Tab 10 mg ...........................................................................................9.12 ‡ Safety cap for extemporaneously compounded oral liquid preparations. CLONAZEPAM Tab 500 µg ..........................................................................................6.26 Tab 2 mg ...........................................................................................11.15 ‡ Oral drops 2.5 mg per ml ....................................................................7.38 100 100 100 100 250 ml 50

Tegretol Tegretol CR Tegretol Tegretol CR Tegretol Frisium

100 100 10 ml OP

Paxam Paxam Rivotril

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

121

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

ETHOSUXIMIDE F Cap 250 mg ......................................................................................32.90 F‡ Oral liq 250 mg per 5 ml ...................................................................13.60 GABAPENTIN – Special Authority see SA1071 below – Retail pharmacy L Cap 100 mg ........................................................................................7.16 L Cap 300 mg – For gabapentin oral liquid formulation refer, page 172 ....................................................................................11.50 L Cap 400 mg ......................................................................................14.75

200 200 ml 100 100 100

Zarontin Zarontin Nupentin Nupentin Nupentin

¾SA1071 Special Authority for Subsidy Initial application — (Epilepsy) from any relevant practitioner. Approvals valid for 15 months for applications meeting the following criteria: Either: 1 Seizures are not adequately controlled with optimal treatment with other antiepilepsy agents; or 2 Seizures are controlled adequately but the patient has experienced unacceptable side effects from optimal treatment with other antiepilepsy agents. Note: "Optimal treatment with other antiepilepsy agents" is deﬁned as treatment with other antiepilepsy agents which are indicated and clinically appropriate for the patient, given in adequate doses for the patient’s age, weight, and other features affecting the pharmacokinetics of the drug with good evidence of compliance. Initial application — (Neuropathic pain) from any relevant practitioner. Approvals valid for 3 months where the patient has tried and failed, or has been unable to tolerate, treatment with a tricyclic antidepressant. Renewal — (Epilepsy) from any relevant practitioner. Approvals valid without further renewal unless notiﬁed where the patient has demonstrated a signiﬁcant and sustained improvement in seizure rate or severity and/or quality of life. Note: As a guideline, clinical trials have referred to a notional 50% reduction in seizure frequency as an indicator of success with anticonvulsant therapy and have assessed quality of life from the patient’s perspective. Renewal — (Neuropathic pain) from any relevant practitioner. Approvals valid for 2 years for applications meeting the following criteria: Either: 1 The patient has demonstrated a marked improvement in their control of pain (prescriber determined); or 2 The patient has previously demonstrated clinical responsiveness to gabapentin and has now developed neuropathic pain in a new site. GABAPENTIN (NEURONTIN) – Special Authority see SA0973 below – Retail pharmacy L Tab 600 mg .......................................................................................67.50 100 Neurontin L Cap 100 mg ......................................................................................13.26 100 Neurontin L Cap 300 mg – For gabapentin (neurontin) oral liquid formulation refer, page 172..................................................................39.76 100 Neurontin L Cap 400 mg ......................................................................................53.01 100 Neurontin ¾SA0973 Special Authority for Subsidy Notes: Subsidy for patients pre-approved by PHARMAC on 1 August 2009. Approvals valid without further renewal unless notiﬁed. No new approvals will be granted from 1 August 2009. LACOSAMIDE – Special Authority see SA1125 on the next page – Retail pharmacy L Tab 50 mg .........................................................................................25.04 14 Vimpat L Tab 100 mg .......................................................................................50.06 14 Vimpat 200.24 56 Vimpat L Tab 150 mg .......................................................................................75.10 14 Vimpat 300.40 56 Vimpat L Tab 200 mg .....................................................................................400.55 56 Vimpat

122

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA1125 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 15 months for applications meeting the following criteria: Both: 1 Patient has partial-onset epilepsy; and 2 Seizures are not adequately controlled by, or patient has experienced unacceptable side effects from, optimal treatment with all of the following: sodium valproate, topiramate, levetiracetam and any two of carbamazepine, lamotrigine and phenytoin sodium (see Note). Note: "Optimal treatment" is deﬁned as treatment which is indicated and clinically appropriate for the patient, given in adequate doses for the patient’s age, weight and other features affecting the pharmacokinetics of the drug with good evidence of compliance. Women of childbearing age are not required to have a trial of sodium valproate. Renewal from any relevant practitioner. Approvals valid for 24 months where the patient has demonstrated a signiﬁcant and sustained improvement in seizure rate or severity and/or quality of life compared with that prior to starting lacosamide treatment (see Note). Note: As a guideline, clinical trials have referred to a notional 50% reduction in seizure frequency as an indicator of success with anticonvulsant therapy and have assessed quality of life from the patient’s perspective. LAMOTRIGINE L Tab dispersible 2 mg ...........................................................................6.74 30 Lamictal L Tab dispersible 5 mg ...........................................................................9.64 30 Lamictal 15.00 56 Arrow-Lamotrigine L Tab dispersible 25 mg .......................................................................19.38 56 Logem 20.40 Arrow-Lamotrigine Mogine 29.09 Lamictal L Tab dispersible 50 mg .......................................................................32.97 56 Logem 34.70 Arrow-Lamotrigine Mogine 47.89 Lamictal L Tab dispersible 100 mg .....................................................................56.91 56 Logem 59.90 Arrow-Lamotrigine Mogine 79.16 Lamictal LEVETIRACETAM Tab 250 mg .......................................................................................24.03 Tab 500 mg – For levetiracetam oral liquid formulation refer, page 172 .................................................................................... 28.71 Tab 750 mg .......................................................................................45.23 PHENOBARBITONE For phenobarbitone oral liquid refer, page 175 F Tab 15 mg .........................................................................................25.00 F Tab 30 mg .........................................................................................26.00 PHENYTOIN SODIUM F Tab 50 mg .........................................................................................42.09 F Cap 30 mg ........................................................................................19.13 F Cap 100 mg ......................................................................................17.21 F‡ Oral liq 30 mg per 5 ml .....................................................................19.16 PRIMIDONE F Tab 250 mg .......................................................................................17.25 60 60 60

Levetiracetam-Rex Levetiracetam-Rex Levetiracetam-Rex

500 500 200 200 200 500 ml 100

PSM PSM Dilantin Infatab Dilantin Dilantin Dilantin Apo-Primidone

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

123

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

SODIUM VALPROATE F Tab 100 mg .......................................................................................13.65 F Tab 200 mg EC .................................................................................27.44 F Tab 500 mg EC .................................................................................52.24 F‡ Oral liq 200 mg per 5 ml ...................................................................20.48 F Inj 100 mg per ml, 4 ml .....................................................................41.50 TOPIRAMATE L Tab 25 mg .........................................................................................11.07 26.04 L Tab 50 mg .........................................................................................18.81 44.26 L Tab 100 mg .......................................................................................31.99 75.25 L Tab 200 mg .......................................................................................55.19 129.85 L Sprinkle cap 15 mg ...........................................................................20.84 L Sprinkle cap 25 mg ...........................................................................26.04 VIGABATRIN – Special Authority see SA1072 below – Retail pharmacy L Tab 500 mg .....................................................................................119.30

100 100 100 300 ml 1 60 60 60 60 60 60 100

Epilim Crushable Epilim Epilim Epilim S/F Liquid Epilim Syrup Epilim IV Arrow-Topiramate Topamax Arrow-Topiramate Topamax Arrow-Topiramate Topamax Arrow-Topiramate Topamax Topamax Topamax Sabril

¾SA1072 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 15 months for applications meeting the following criteria: Both: 1 Either: 1.1 Patient has infantile spasms; or 1.2 Both: 1.2.1 Patient has epilepsy; and 1.2.2 Either: 1.2.2.1 Seizures are not adequately controlled with optimal treatment with other antiepilepsy agents; or 1.2.2.2 Seizures are controlled adequately but the patient has experienced unacceptable side effects from optimal treatment with other antiepilepsy agents; and 2 Either: 2.1 Patient is, or will be, receiving regular automated visual ﬁeld testing (ideally before starting therapy and on a 6-monthly basis thereafter); or 2.2 It is impractical or impossible (due to comorbid conditions) to monitor the patient’s visual ﬁelds. Notes: “Optimal treatment with other antiepilepsy agents” is deﬁned as treatment with other antiepilepsy agents which are indicated and clinically appropriate for the patient, given in adequate doses for the patient’s age, weight, and other features affecting the pharmacokinetics of the drug with good evidence of compliance. Vigabatrin is associated with a risk of irreversible visual ﬁeld defects, which may be asymptomatic in the early stages. Renewal from any relevant practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Both: 1 The patient has demonstrated a signiﬁcant and sustained improvement in seizure rate or severity and or quality of life; and 2 Either: 2.1 Patient is receiving regular automated visual ﬁeld testing (ideally every 6 months) on an ongoing basis for duration of treatment with vigabatrin; or 2.2 It is impractical or impossible (due to comorbid conditions) to monitor the patient’s visual ﬁelds. Notes: As a guideline, clinical trials have referred to a notional 50% reduction in seizure frequency as an indicator of success with anticonvulsant therapy and have assessed quality of life from the patient’s perspective. Vigabatrin is associated with a risk of irreversible visual ﬁeld defects, which may be asymptomatic in the early stages.

124

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Antimigraine Preparations

For Anti-inﬂammatory NSAIDS refer to MUSCULOSKELETAL, page 97

Acute Migraine Treatment

ERGOTAMINE TARTRATE WITH CAFFEINE Tab 1 mg with caffeine 100 mg .........................................................31.00 METOCLOPRAMIDE HYDROCHLORIDE WITH PARACETAMOL Tab 5 mg with paracetamol 500 mg ....................................................6.77 RIZATRIPTAN BENZOATE Wafer 10 mg .....................................................................................25.32 SUMATRIPTAN Tab 50 mg ...........................................................................................1.55 38.83 Tab 100 mg .........................................................................................1.55 77.66 Inj 12 mg per ml, 0.5 ml – Maximum of 10 inj per prescription .........36.00 100 60 3 4 100 2 100 2 OP

Cafergot Paramax Maxalt Melt Arrow-Sumatriptan Arrow-Sumatriptan Arrow-Sumatriptan Arrow-Sumatriptan Arrow-Sumatriptan

Prophylaxis of Migraine

For Beta Adrenoceptor Blockers refer to CARDIOVASCULAR SYSTEM, page 50 CLONIDINE HYDROCHLORIDE F Tab 25 µg ..........................................................................................19.25 PIZOTIFEN F Tab 500 µg ........................................................................................21.10

100 100

Dixarit Sandomigran

Antinausea and Vertigo Agents

For Antispasmodics refer to ALIMENTARY TRACT, page 28 APREPITANT – Special Authority see SA0987 below – Retail pharmacy Cap 2 × 80 mg and 1 × 125 mg ....................................................116.00

3 OP

Emend Tri-Pack

¾SA0987 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 12 months where the patient is undergoing highly emetogenic chemotherapy and/or anthracycline-based chemotherapy for the treatment of malignancy. Renewal from any relevant practitioner. Approvals valid for 12 months where the patient is undergoing highly emetogenic chemotherapy and/or anthracycline-based chemotherapy for the treatment of malignancy. BETAHISTINE DIHYDROCHLORIDE F Tab 16 mg ...........................................................................................9.26 84 Vergo 16 CYCLIZINE HYDROCHLORIDE Tab 50 mg ...........................................................................................1.59 CYCLIZINE LACTATE Inj 50 mg per ml, 1 ml .......................................................................14.95 DOMPERIDONE F Tab 10 mg – For domperidone oral liquid formulation refer, page 172 ......................................................................................7.99 10 5

Nausicalm Nausicalm

100

Motilium

HYOSCINE (SCOPOLAMINE) – Special Authority see SA0939 on the next page – Retail pharmacy Patch 1.5 mg ....................................................................................11.95 2 Scopoderm TTS

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

125

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA0939 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 Control of intractable nausea, vomiting, or inability to swallow saliva in the treatment of malignancy or chronic disease; and 2 Patient cannot tolerate or does not adequately respond to oral anti-nausea agents; and 3 The applicant must specify the underlying malignancy or chronic disease. Renewal from any relevant practitioner. Approvals valid for 1 year where the treatment remains appropriate and the patient is beneﬁting from treatment. HYOSCINE HYDROBROMIDE F Inj 400 µg per ml, 1 ml ........................................................................6.66 5 Mayne METOCLOPRAMIDE HYDROCHLORIDE F Tab 10 mg ...........................................................................................3.95 F Inj 5 mg per ml, 2 ml – Up to 5 inj available on a PSO .......................4.50 ONDANSETRON Tab 4 mg .............................................................................................5.10 Tab disp 4 mg .....................................................................................1.70 Tab 8 mg .............................................................................................1.70 Tab disp 8 mg .....................................................................................2.00 PROCHLORPERAZINE F Tab 3 mg buccal .................................................................................5.97 (15.00) F Tab 5 mg – Up to 30 tab available on a PSO....................................16.85 F Inj 12.5 mg per ml, 1 ml – Up to 5 inj available on a PSO ................25.81 F Suppos 25 mg ..................................................................................23.87 PROMETHAZINE THEOCLATE F Tab 25 mg ...........................................................................................1.20 (6.24) TROPISETRON a) Maximum of 6 cap per prescription b) Maximum of 3 cap per dispensing c) Not more than one prescription per month. Cap 5 mg ..........................................................................................77.41 100 10 30 10 10 10

Metamide Pﬁzer Dr Reddy’s

Ondansetron

Dr Reddy’s

Ondansetron

Dr Reddy’s

Ondansetron

Dr Reddy’s

Ondansetron

50 Buccastem 500 10 5 10 Avomine

Antinaus Stemetil Stemetil

Navoban

126

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Antipsychotics

Guidelines for the use of atypical antipsychotic agents Diagnosis: Schizophrenia and related psychoses when positive symptoms (delusions, hallucinations and thought disorder) are prominent and/or disabling or when both positive symptoms and negative symptoms (ﬂattened affect, emotional and social withdrawal and poverty of speech) are present. Treatment: Before initiating atypical antipsychotic therapy, physicians should consider whether the patient is likely to respond to and/or tolerate conventional antipsychotic therapy and, where appropriate, trial one or more conventional agent prior to use of an atypical agent.

General

AMISULPRIDE Tab 100 mg .......................................................................................22.52 Tab 200 mg .......................................................................................97.03 Tab 400 mg .....................................................................................185.44 Oral liq 100 mg per ml ......................................................................55.44 ARIPIPRAZOLE – Special Authority see SA0920 below – Retail pharmacy Tab 10 mg .......................................................................................123.54 Tab 15 mg .......................................................................................175.28 Tab 20 mg .......................................................................................213.42 Tab 30 mg .......................................................................................260.07 30 60 60 60 ml 30 30 30 30

Solian Solian Solian Solian Abilify Abilify Abilify Abilify

¾SA0920 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 2 years for applications meeting the following criteria: Both: 1 Patient is suffering from schizophrenia or related psychoses; and 2 Either: 2.1 An effective dose of risperidone or quetiapine has been trialled and has been discontinued, or is in the process of being discontinued, because of unacceptable side effects; or 2.2 An effective dose of risperidone or quetiapine has been trialled and has been discontinued, or is in the process of being discontinued, because of inadequate clinical response. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment. CHLORPROMAZINE HYDROCHLORIDE Tab 10 mg – Up to 30 tab available on a PSO..................................12.36 100 Largactil Tab 25 mg – Up to 30 tab available on a PSO..................................13.02 100 Largactil Tab 100 mg – Up to 30 tab available on a PSO................................30.61 100 Largactil Inj 25 mg per ml, 2 ml – Up to 5 inj available on a PSO ...................25.66 10 Largactil CLOZAPINE – Hospital pharmacy [HP4] Tab 25 mg .........................................................................................13.37 26.74 6.69 13.37 Tab 50 mg ...........................................................................................8.67 17.33 Tab 100 mg .......................................................................................34.65 69.30 17.33 34.65 Tab 200 mg .......................................................................................34.65 69.30 Suspension 50 mg per ml .................................................................17.33

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

50 100 50 100 50 100 50 100 50 100 50 100 100 ml

Clozaril Clozaril Clopine Clopine Clopine Clopine Clozaril Clozaril Clopine Clopine Clopine Clopine Clopine 127

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

HALOPERIDOL Tab 500 µg – Up to 30 tab available on a PSO...................................5.42 Tab 1.5 mg – Up to 30 tab available on a PSO...................................8.20 Tab 5 mg – Up to 30 tab available on a PSO....................................25.84 Oral liq 2 mg per ml – Up to 200 ml available on a PSO ..................19.87 Inj 5 mg per ml, 1 ml – Up to 5 inj available on a PSO .....................18.74 LEVOMEPROMAZINE Tab 25 mg .........................................................................................16.93 Tab 100 mg .......................................................................................43.96 Inj 25 mg per ml, 1 ml .......................................................................73.68 LITHIUM CARBONATE Tab 250 mg .......................................................................................36.10 Tab 400 mg .......................................................................................13.50 Tab long-acting 400 mg ....................................................................18.50 Cap 250 mg ........................................................................................9.42 OLANZAPINE Tab 2.5 mg ..........................................................................................2.00

100 100 100 100 ml 10 100 100 10 500 100 100 100 28

Serenace Serenace Serenace Serenace Serenace Nozinan Nozinan Nozinan Lithicarb Lithicarb Priadel Douglas Dr Reddy’s

Olanzapine

Olanzine

(51.07) Tab 5 mg .............................................................................................3.85 Zyprexa 28

Dr Reddy’s

Olanzapine

Olanzine

(101.21) Tab 10 mg ...........................................................................................6.35 Zyprexa 28

Dr Reddy’s

Olanzapine

Olanzine

(204.49) PERICYAZINE Tab 2.5 mg ........................................................................................12.49 Tab 10 mg .........................................................................................44.45 QUETIAPINE Tab 25 mg ...........................................................................................7.00 100 100 60 Zyprexa

Neulactil Neulactil Dr Reddy’s

Quetiapine

16.78 Tab 100 mg .......................................................................................14.00

90 60

Seroquel Quetapel Dr Reddy’s

Quetiapine

32.59 Tab 200 mg .......................................................................................24.00

90 60

Seroquel Quetapel Dr Reddy’s

Quetiapine

56.70 Tab 300 mg .......................................................................................40.00

90 60

Seroquel Quetapel Dr Reddy’s

Quetiapine

95.40

Seroquel Quetapel

128

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

RISPERIDONE Tab 0.5 mg ..........................................................................................3.51

Apo-Risperidone Dr Reddy’s

Risperidone

5.20 Tab 1 mg .............................................................................................6.00

20 60

Ridal Risperdal Apo-Risperidone Dr Reddy’s

Risperidone

30.77 Tab 2 mg ...........................................................................................11.00

Ridal Risperdal Apo-Risperidone Dr Reddy’s

Risperidone

61.53 Tab 3 mg ...........................................................................................15.00

Ridal Risperdal Apo-Risperidone Dr Reddy’s

Risperidone

92.32 Tab 4 mg ...........................................................................................20.00

Ridal Risperdal Apo-Risperidone Dr Reddy’s

Risperidone

123.05 Oral liq 1 mg per ml ..........................................................................18.35 45.92 TRIFLUOPERAZINE HYDROCHLORIDE Tab 1 mg .............................................................................................9.83 Tab 2 mg ...........................................................................................14.64 Tab 5 mg ...........................................................................................16.66

30 ml

Ridal Risperdal Apo-Risperidone Risperon Risperdal Stelazine Stelazine Stelazine

100 100 100

ZIPRASIDONE – Subsidy by endorsement Ziprasidone is subsidised for patients suffering from schizophrenia or related psychoses after a trial of an effective dose of risperidone or quetiapine that has been discontinued, or is in the process of being discontinued, because of unacceptable side effects or inadequate response, and the prescription is endorsed accordingly. Cap 20 mg ........................................................................................87.88 60 Zeldox Cap 40 mg ......................................................................................164.78 60 Zeldox Cap 60 mg ......................................................................................247.17 60 Zeldox Cap 80 mg ......................................................................................329.56 60 Zeldox ZUCLOPENTHIXOL HYDROCHLORIDE Tab 10 mg .........................................................................................31.45 100

Clopixol

Depot Injections

FLUPENTHIXOL DECANOATE Inj 20 mg per ml, 1 ml – Up to 5 inj available on a PSO ...................13.14 Inj 20 mg per ml, 2 ml – Up to 5 inj available on a PSO ...................20.90 Inj 100 mg per ml, 1 ml – Up to 5 inj available on a PSO .................40.87 5 5 5

Fluanxol Fluanxol Fluanxol

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

129

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

FLUPHENAZINE DECANOATE Inj 12.5 mg per 0.5 ml, 0.5 ml – Up to 5 inj available on a PSO .........17.60 Inj 25 mg per ml, 1 ml – Up to 5 inj available on a PSO ...................27.90 Inj 100 mg per ml, 1 ml – Up to 5 inj available on a PSO ...............154.50 HALOPERIDOL DECANOATE Inj 50 mg per ml, 1 ml – Up to 5 inj available on a PSO ...................28.39 Inj 100 mg per ml, 1 ml – Up to 5 inj available on a PSO .................55.90

5 5 5 5 5

Modecate Modecate Modecate Haldol Haldol Concentrate

OLANZAPINE PAMOATE MONOHYDRATE – Special Authority see SA1146 below – Retail pharmacy Inj 210 mg .......................................................................................280.00 1 Zyprexa Relprevv Inj 300 mg .......................................................................................460.00 1 Zyprexa Relprevv Inj 405 mg .......................................................................................560.00 1 Zyprexa Relprevv ¾SA1146 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 The patient has schizophrenia; and 2 The patient has tried but failed to comply with treatment using oral atypical antipsychotic agents; and 3 The patient has been admitted to hospital or treated in respite care, or intensive outpatient or home-based treatment for 30 days or more in the last 12 months. Renewal from any relevant practitioner. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has had less than 12 months’ treatment with olanzapine depot injection; and 1.2 There is no clinical reason to discontinue treatment; or 2 The initiation of olanzapine depot injection has been associated with fewer days of intensive intervention than was the case during a corresponding period of time prior to the initiation of olanzapine depot injection. Note: The patient should be monitored for post-injection syndrome for at least three hours after each injection. PIPOTHIAZINE PALMITATE Inj 50 mg per ml, 1 ml – Up to 5 inj available on a PSO .................178.48 10 Piportil Inj 50 mg per ml, 2 ml – Up to 5 inj available on a PSO .................353.32 10 Piportil RISPERIDONE – Special Authority see SA0926 below – Retail pharmacy Inj 25 mg per 2 ml ...........................................................................175.00 Inj 37.5 mg per 2 ml ........................................................................230.00 Inj 50 mg per 2 ml ...........................................................................280.00 1 1 1

Risperdal Consta Risperdal Consta Risperdal Consta

¾SA0926 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 The patient has schizophrenia or other psychotic disorder; and 2 Has tried but failed to comply with treatment using oral atypical antipsychotic agents; and 3 Has been admitted to hospital or treated in respite care, or intensive outpatient or home-based treatment for 30 days or more in last 12 months. Renewal from any relevant practitioner. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has had less than 12 months treatment with risperidone depot injection; and 1.2 There is no clinical reason to discontinue treatment; or 2 The initiation of risperidone depot injection has been associated with fewer days of intensive intervention than was the case during a corresponding period of time prior to the initiation of risperidone depot injection. Note: Risperidone depot injection should ideally be used as monotherapy (i.e. without concurrent use of any other antipsychotic medication). In some cases, it may be clinically appropriate to attempt to treat a patient with typical antipsychotic agents in depot injectable form before trialing risperidone depot injection.

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

130

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

ZUCLOPENTHIXOL DECANOATE Inj 200 mg per ml, 1 ml – Up to 5 inj available on a PSO .................19.80

Clopixol

Orodispersible Antipsychotics

OLANZAPINE Orodispersible tab 5 mg .....................................................................6.36 28

Dr Reddy’s

Olanzapine

Orodispersible tab 10 mg ...................................................................8.76

Olanzine-D Dr Reddy’s

Olanzapine

Olanzine-D

Wafer 5 mg .........................................................................................6.36 (102.19) Wafer 10 mg .......................................................................................8.76 (204.37) RISPERIDONE – Special Authority see SA0927 below – Retail pharmacy Orally-disintegrating tablets 0.5 mg ..................................................21.42 Orally-disintegrating tablets 1 mg .....................................................42.84 Orally-disintegrating tablets 2 mg .....................................................85.71 28 Zyprexa Zydis 28 Zyprexa Zydis 28 28 28

Risperdal Quicklet Risperdal Quicklet Risperdal Quicklet

¾SA0927 Special Authority for Subsidy Initial application — (Acute situations) from any relevant practitioner. Approvals valid for 6 weeks for applications meeting the following criteria: Both: 1 For a non-adherent patient on oral therapy with standard risperidone tablets or risperidone oral liquid; and 2 The patient is under direct supervision for administration of medicine. Initial application — (Chronic situations) from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The patient is unable to take standard risperidone tablets or oral liquid, or once stabilized refuses to take risperidone tablets or oral liquid; and 2 The patient is under direct supervision for administration of medicine. Renewal from any relevant practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The patient is unable to take standard risperidone tablets or oral liquid, or once stabilized refuses to take risperidone tablets or oral liquid; and 2 The patient is under direct supervision for administration of medicine. Note: Risperdal Quicklets cost signiﬁcantly more than risperidone tablets and should only be used where necessary.

Anxiolytics

ALPRAZOLAM Tab 250 µg ..........................................................................................3.15 50 Arrow-Alprazolam ‡ Safety cap for extemporaneously compounded oral liquid preparations. Tab 500 µg ..........................................................................................4.10 50 Arrow-Alprazolam ‡ Safety cap for extemporaneously compounded oral liquid preparations. Tab 1 mg .............................................................................................7.25 50 Arrow-Alprazolam ‡ Safety cap for extemporaneously compounded oral liquid preparations. BUSPIRONE HYDROCHLORIDE – Special Authority see SA0863 on the next page – Retail pharmacy Tab 5 mg ...........................................................................................28.00 100 Paciﬁc Buspirone Tab 10 mg .........................................................................................17.00 100 Paciﬁc Buspirone

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

131

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA0863 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 2 years for applications meeting the following criteria: Both: 1 For use only as an anxiolytic; and 2 Other agents are contraindicated or have failed. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment. DIAZEPAM Tab 2 mg ...........................................................................................11.44 500 Arrow-Diazepam ‡ Safety cap for extemporaneously compounded oral liquid preparations. Tab 5 mg ...........................................................................................13.71 500 Arrow-Diazepam ‡ Safety cap for extemporaneously compounded oral liquid preparations. LORAZEPAM Tab 1 mg ...........................................................................................16.42 250 Ativan ‡ Safety cap for extemporaneously compounded oral liquid preparations. Tab 2.5 mg ........................................................................................11.17 100 Ativan ‡ Safety cap for extemporaneously compounded oral liquid preparations. OXAZEPAM Tab 10 mg ...........................................................................................5.89 100 Ox-Pam ‡ Safety cap for extemporaneously compounded oral liquid preparations. Tab 15 mg ...........................................................................................8.13 100 Ox-Pam ‡ Safety cap for extemporaneously compounded oral liquid preparations.

Multiple Sclerosis Treatments

¾SA1062 Special Authority for Subsidy Special Authority approved by the Multiple Sclerosis Treatment Committee Notes: Budget managed by appointed clinicians on the Multiple Sclerosis Treatment Assessments Committee (MSTAC). Applications will be considered by MSTAC at its regular meetings and approved subject to eligibility according to the Entry and Stopping criteria (below). Application details may be obtained from PHARMAC’s website http://www.pharmac.govt.nz or: The coordinator Phone: 04 460 4990 Multiple Sclerosis Treatment Assessment Committee Facsimile: 04 916 7571 PHARMAC PO Box 10 254 Email: mstaccoordinator@pharmac.govt.nz Wellington Completed application forms must be sent to the coordinator for MSTAC and will be considered by MSTAC at the next practicable opportunity. Notiﬁcation of MSTAC’s decision will be sent to the patient, the applying clinician and the patient’s GP (if speciﬁed). These agents will NOT be subsidised if dispensed from a community or hospital pharmacy. Regular supplies will be distributed to all approved patients or their clinicians by courier. Prescribers must send quarterly prescriptions for approved patients to the MSTAC coordinator. Only prescriptions for 6 million iu of interferon beta-1-alpha per week, or 8 million iu of interferon beta-1-beta every other day, or 20 mg glatiramer acetate daily will be subsidised. Appeals against MSTAC’s decision and/or the processing of any application may be lodged with the MSTAC coordinator. Concerns that cannot be or have not been adequately addressed by MSTAC will be forwarded to a separate Appeal Committee if necessary. Switching between treatments is permitted within the 12 month approval period without reapproval by MSTAC. The MSTAC coordinator should be notiﬁed of the change and a new prescription provided. Entry Criteria continued. . .

132

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . .

1) Diagnosis of multiple sclerosis (MS) must be conﬁrmed by a neurologist. Diagnosis should as a rule include MRI conﬁrmation. For patients diagnosed before MRI was widely utilised in New Zealand, conﬁrmation of diagnosis via clinical assessment and laboratory/ancillary data must be provided; and 2) patients must have active relapsing MS (conﬁrmed by MR scan where necessary) with or without underlying progression; and 3) patients must have either: a) EDSS score 2.5 - 5.5 with 2+ relapses: G experienced at least 2 signiﬁcant relapses of MS in the previous 12 months, and G an EDSS score of between 2.5 and 5.5 inclusive; or b) EDSS score 2.0 with 3+ relapses: G experienced at least 3 signiﬁcant relapses of MS in the previous 12 months, and G an EDSS score of 2.0; and 4) Each relapse must: a) be conﬁrmed by a neurologist or general physician (the patient may not necessarily have been seen during the relapse but the neurologist/physician must be satisﬁed that the clinical features were characteristic and met the speciﬁed criteria); b) be associated with characteristic new symptom(s)/sign(s) or substantial worsening of previously experienced symptom(s)/sign(s); c) last at least one week; d) follow a period of stability of at least one month; e) be severe enough to change either the EDSS or at least one of the Kurtzke functional systems scores by at least 1 point; f) be distinguishable from the effects of general fatigue; and g) not be associated with a fever (T>37.5◦ C); and 5) applications must be made at least four weeks after the date of the onset of the last known relapse; and 6) patients must have no previous history of lack of response to beta-interferon or glatiramer acetate (see criteria for stopping). 7) applications must be submitted to the Multiple Sclerosis Treatment Assessment Committee (MSTAC) by the patient’s neurologist or a general physician; and 8) patients must agree (via informed consent) to co-operate if as a result of their meeting the stopping criteria, funding is withdrawn. Patients must agree to the collection of clinical data relating to their MS and use of those data by PHARMAC; and 9) patients must agree to allow clinical data to be collected and reviewed by MSTAC annually for each year in which they receive funding for beta-interferon or glatiramer acetate. Stopping Criteria 1) Conﬁrmed progression of disability that is sustained for six months during a minimum of one year of treatment. Progression of disability is deﬁned as any of: a) an increase of 2 EDSS points where starting EDSS was 2.0; or b) an increase of 1.5 EDSS points where starting EDSS was 2.5 or 3.0; or c) an increase of 1 EDSS point where starting EDSS 3.5 or greater; or d) an increase in EDSS score to 6.0 or more; or 2) stable or increasing relapse rate over 12 months of treatment (compared with the relapse rate on starting treatment)(see note); or 3) pregnancy and/or lactation; or 4) within the 12 month approval year, intolerance to interferon beta-1-alpha, and/or interferon beta-1-beta and/or glatiramer acetate; or 5) non-compliance with treatment, including refusal to undergo annual assessment or refusal to allow the results of the assessment to be submitted to MSTAC; or continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

133

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 6) patients may, subject to conclusions drawn from published evidence available at the time, be excluded if they develop a high titre of neutralising anti-bodies to beta-interferon or glatiramer acetate. Note: Patients who have a stable or increasing relapse rate over 12 months of treatment (compared with the relapse rate on starting treatment) and who do not meet any of the other Stopping Criteria at annual review may switch to a different class of funded treatment (i.e. patients may switch from either of the beta-interferons [interferon beta-1-beta or interferon beta-1-alpha] to glatiramer acetate or vice versa). Patients may switch classes of treatment for this reason only once, after which they will be required to stop funded treatment if they meet any of the Stopping Criteria at annual review (including the criterion relating to stable or increasing relapse rate over 12 months of treatment). GLATIRAMER ACETATE – Special Authority see SA1062 on page 132 Inj 20 mg preﬁlled syringe ...........................................................1,089.25 28 Copaxone INTERFERON BETA-1-ALPHA – Special Authority see SA1062 on page 132 Inj 6 million iu preﬁlled syringe ....................................................1,425.10 Inj 6 million iu per vial ..................................................................1,425.10 INTERFERON BETA-1-BETA – Special Authority see SA1062 on page 132 Inj 8 million iu per 1 ml .................................................................1,322.89 4 4 15

Avonex Avonex Betaferon

Sedatives and Hypnotics

LORMETAZEPAM Tab 1 mg .............................................................................................3.11 (23.50) ‡ Safety cap for extemporaneously compounded oral liquid preparations. MIDAZOLAM Tab 7.5 mg .......................................................................................10.38 (25.00) ‡ Safety cap for extemporaneously compounded oral liquid preparations. Inj 1 mg per ml, 5 ml .........................................................................10.75 (14.73) Inj 5 mg per ml, 3 ml .........................................................................11.90 (19.64) (Hypnovel Tab 7.5 mg to be delisted 1 March 2012) NITRAZEPAM Tab 5 mg .............................................................................................2.00 (4.98) ‡ Safety cap for extemporaneously compounded oral liquid preparations. TEMAZEPAM Tab 10 mg ...........................................................................................1.27 ‡ Safety cap for extemporaneously compounded oral liquid preparations. TRIAZOLAM Tab 125 µg ..........................................................................................5.10 (7.25) ‡ Safety cap for extemporaneously compounded oral liquid preparations. Tab 250 µg ..........................................................................................4.10 (8.70) ‡ Safety cap for extemporaneously compounded oral liquid preparations. ZOPICLONE Tab 7.5 mg ........................................................................................11.90 30 Noctamid

100 Hypnovel 10 5

Hypnovel

Pﬁzer

Hypnovel

Pﬁzer

100 Nitrados

Normison

100 Hypam 100 Hypam

500

Apo-Zopiclone

134

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Stimulants/ADHD Treatments Stimulants/ADHD treatments

ATOMOXETINE – Special Authority see SA0951 below – Retail pharmacy Cap 10 mg ......................................................................................107.03 Cap 18 mg ......................................................................................107.03 Cap 25 mg ......................................................................................107.03 Cap 40 mg ......................................................................................107.03 Cap 60 mg ......................................................................................107.03 Cap 80 mg ......................................................................................139.11 Cap 100 mg ....................................................................................139.11 28 28 28 28 28 28 28

Strattera Strattera Strattera Strattera Strattera Strattera Strattera

¾SA0951 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 Patient has ADHD (Attention Deﬁcit and Hyperactivity Disorder) diagnosed according to DSM-IV or ICD 10 criteria; and 2 Once-daily dosing; and 3 Any of the following: 3.1 Treatment with a subsidised formulation of a stimulant has resulted in the development or worsening of serious adverse reactions or where the combination of subsidised stimulant treatment with another agent would pose an unacceptable medical risk; or 3.2 Treatment with a subsidised formulation of a stimulant has resulted in worsening of co-morbid substance abuse or there is a signiﬁcant risk of diversion with subsidised stimulant therapy; or 3.3 An effective dose of a subsidised formulation of a stimulant has been trialled and has been discontinued because of inadequate clinical response; and 4 The patient will not be receiving treatment with atomoxetine in combination with a subsidised formulation of a stimulant, except for the purposes of transitioning from subsidised stimulant therapy to atomoxetine. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment. Note: A "subsidised formulation of a stimulant" refers to currently subsidised methylphenidate hydrochloride tablet formulations (immediate-release, sustained-release and extended-release) or dexamphetamine sulphate tablets. DEXAMPHETAMINE SULPHATE – Special Authority see SA1149 below – Retail pharmacy Only on a controlled drug form Tab 5 mg ...........................................................................................16.50 100 PSM ¾SA1149 Special Authority for Subsidy Initial application — (ADHD in patients 5 or over) only from a paediatrician, psychiatrist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 24 months for applications meeting the following criteria: All of the following: 1 ADHD (Attention Deﬁcit and Hyperactivity Disorder) patients aged 5 years or over; and 2 Diagnosed according to DSM-IV or ICD 10 criteria; and 3 Either: 3.1 Applicant is a paediatrician or psychiatrist; or 3.2 Applicant is a medical practitioner and conﬁrms that a relevant specialist has been consulted within the last 2 years and has recommended treatment for the patient. Initial application — (ADHD in patients under 5) only from a paediatrician or psychiatrist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 ADHD (Attention Deﬁcit and Hyperactivity Disorder) patients under 5 years of age; and continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

135

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 2 Diagnosed according to DSM-IV or ICD 10 criteria. Initial application — (Narcolepsy) only from a neurologist or respiratory specialist. Approvals valid for 24 months where the patient suffers from narcolepsy. Renewal — (ADHD in patients 5 or over) only from a paediatrician, psychiatrist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 24 months for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 Either: 2.1 Applicant is a paediatrician or psychiatrist; or 2.2 Applicant is a medical practitioner and conﬁrms that a relevant specialist has been consulted within the last 2 years and has recommended treatment for the patient. Renewal — (ADHD in patients under 5) only from a paediatrician or psychiatrist. Approvals valid for 12 months where the treatment remains appropriate and the patient is beneﬁting from treatment. Renewal — (Narcolepsy) only from a neurologist or respiratory specialist. Approvals valid for 24 months where the treatment remains appropriate and the patient is beneﬁting from treatment. METHYLPHENIDATE HYDROCHLORIDE – Special Authority see SA1150 below – Retail pharmacy Only on a controlled drug form Tab immediate-release 5 mg ..............................................................3.20 30 Rubifen Tab immediate-release 10 mg ............................................................3.00 30 Ritalin Rubifen Tab immediate-release 20 mg ............................................................7.85 30 Rubifen Tab sustained-release 20 mg ...........................................................10.95 30 Rubifen SR 50.00 100 Ritalin SR ¾SA1150 Special Authority for Subsidy Initial application — (ADHD in patients 5 or over) only from a paediatrician, psychiatrist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 24 months for applications meeting the following criteria: All of the following: 1 ADHD (Attention Deﬁcit and Hyperactivity Disorder) patients aged 5 years or over; and 2 Diagnosed according to DSM-IV or ICD 10 criteria; and 3 Either: 3.1 Applicant is a paediatrician or psychiatrist; or 3.2 Applicant is a medical practitioner and conﬁrms that a relevant specialist has been consulted within the last 2 years and has recommended treatment for the patient. Initial application — (ADHD in patients under 5) only from a paediatrician or psychiatrist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 ADHD (Attention Deﬁcit and Hyperactivity Disorder) patients under 5 years of age; and 2 Diagnosed according to DSM-IV or ICD 10 criteria. Initial application — (Narcolepsy) only from a neurologist or respiratory specialist. Approvals valid for 24 months where the patient suffers from narcolepsy. Renewal — (ADHD in patients 5 or over) only from a paediatrician, psychiatrist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 24 months for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 Either: 2.1 Applicant is a paediatrician or psychiatrist; or 2.2 Applicant is a medical practitioner and conﬁrms that a relevant specialist has been consulted within the last 2 years and has recommended treatment for the patient. continued. . .

136

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . Renewal — (ADHD in patients under 5) only from a paediatrician or psychiatrist. Approvals valid for 12 months where the treatment remains appropriate and the patient is beneﬁting from treatment. Renewal — (Narcolepsy) only from a neurologist or respiratory specialist. Approvals valid for 24 months where the treatment remains appropriate and the patient is beneﬁting from treatment. METHYLPHENIDATE HYDROCHLORIDE EXTENDED-RELEASE – Special Authority see SA1151 below – Retail pharmacy Only on a controlled drug form Tab extended-release 18 mg ............................................................58.96 30 Concerta Tab extended-release 27 mg ............................................................65.44 30 Concerta Tab extended-release 36 mg ............................................................71.93 30 Concerta Tab extended-release 54 mg ............................................................86.24 30 Concerta Cap modiﬁed-release 10 mg ............................................................19.50 30 Ritalin LA Cap modiﬁed-release 20 mg ............................................................25.50 30 Ritalin LA Cap modiﬁed-release 30 mg ............................................................31.90 30 Ritalin LA Cap modiﬁed-release 40 mg ............................................................38.25 30 Ritalin LA ¾SA1151 Special Authority for Subsidy Initial application only from a paediatrician, psychiatrist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 24 months for applications meeting the following criteria: All of the following: 1 ADHD (Attention Deﬁcit and Hyperactivity Disorder); and 2 Diagnosed according to DSM-IV or ICD 10 criteria; and 3 Either: 3.1 Applicant is a paediatrician or psychiatrist; or 3.2 Applicant is a medical practitioner and conﬁrms that a relevant specialist has been consulted within the last 2 years and has recommended treatment for the patient; and 4 Either: 4.1 Patient is taking a currently subsidised formulation of methylphenidate hydrochloride (immediate-release or sustainedrelease) which has not been effective due to signiﬁcant administration and/or compliance difﬁculties; or 4.2 There is signiﬁcant concern regarding the risk of diversion or abuse of immediate-release methylphenidate hydrochloride. Renewal only from a paediatrician, psychiatrist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 24 months for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 Either: 2.1 Applicant is a paediatrician or psychiatrist; or 2.2 Applicant is a medical practitioner and conﬁrms that a relevant specialist has been consulted within the last 2 years and has recommended treatment for the patient. MODAFINIL – Special Authority see SA1126 below – Retail pharmacy Tab 100 mg .......................................................................................72.50 30 Modavigil

¾SA1126 Special Authority for Subsidy Initial application only from a neurologist or respiratory specialist. Approvals valid for 24 months for applications meeting the following criteria: All of the following: 1 The patient has a diagnosis of narcolepsy and has excessive daytime sleepiness associated with narcolepsy occurring almost daily for three months or more; and 2 Either: continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

137

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 2.1 The patient has a multiple sleep latency test with a mean sleep latency of less than or equal to 10 minutes and 2 or more sleep onset rapid eye movement periods; or 2.2 The patient has at least one of: cataplexy, sleep paralysis or hypnagogic hallucinations; and 3 Either: 3.1 An effective dose of a subsidised formulation of methylphenidate or dexamphetamine has been trialled and discontinued because of intolerable side effects; or 3.2 Methylphenidate and dexamphetamine are contraindicated. Renewal only from a neurologist or respiratory specialist. Approvals valid for 24 months where the treatment remains appropriate and the patient is beneﬁting from treatment.

Treatments for Dementia

DONEPEZIL HYDROCHLORIDE F Tab 5 mg .............................................................................................7.71 F Tab 10 mg .........................................................................................14.06 90 90

Donepezil-Rex Donepezil-Rex

Treatments for Opioid Overdose

NALOXONE HYDROCHLORIDE a) Up to 5 inj available on a PSO b) Only on a PSO F Inj 400 µg per ml, 1 ml ......................................................................33.00

Mayne

Treatments for Substance Dependence

BUPROPION HYDROCHLORIDE Tab modiﬁed-release 150 mg ...........................................................65.00 DISULFIRAM Tab 200 mg .......................................................................................24.30 30 100

Zyban Antabuse Naltraccord

NALTREXONE HYDROCHLORIDE – Special Authority see SA0909 below – Retail pharmacy Tab 50 mg .......................................................................................123.00 30

¾SA0909 Special Authority for Subsidy Initial application from any medical practitioner. Approvals valid for 3 months for applications meeting the following criteria: Both: 1 Patient is currently enrolled in a recognised comprehensive treatment programme for alcohol dependence; and 2 Applicant works in or with a community Alcohol and Drug Service contracted to one of the District Health Boards or accredited against the New Zealand Alcohol and Other Drug Sector Standard or the National Mental Health Sector Standard. Renewal from any medical practitioner. Approvals valid for 3 months for applications meeting the following criteria: Both: 1 Compliance with the medication (prescriber determined); and 2 Any of the following: 2.1 Patient is still unstable and requires further treatment; or 2.2 Patient achieved signiﬁcant improvement but requires further treatment; or 2.3 Patient is well controlled but requires maintenance therapy. The patient may not have had more than 1 prior approval in the last 12 months.

138

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

NERVOUS SYSTEM

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

NICOTINE Nicotine will not be funded Close Control in amounts less than 4 weeks of treatment. Patch 7 mg – Up to 28 patch available on a PSO ............................18.13 28 Patch 14 mg – Up to 28 patch available on a PSO ..........................18.81 28 Patch 21 mg – Up to 28 patch available on a PSO ..........................19.14 28 Lozenge 1 mg – Up to 216 loz available on a PSO..........................19.94 216 Lozenge 2 mg – Up to 216 loz available on a PSO..........................24.27 216 Gum 2 mg (Classic) – Up to 384 piece available on a PSO.............36.47 384 Gum 2 mg (Fruit) – Up to 384 piece available on a PSO .................36.47 384 Gum 2 mg (Mint) – Up to 384 piece available on a PSO..................36.47 384 Gum 4 mg (Classic) – Up to 384 piece available on a PSO.............42.04 384 Gum 4 mg (Fruit) – Up to 384 piece available on a PSO .................42.04 384 Gum 4 mg (Mint) – Up to 384 piece available on a PSO..................42.04 384

Habitrol Habitrol Habitrol Habitrol Habitrol Habitrol Habitrol Habitrol Habitrol Habitrol Habitrol

VARENICLINE TARTRATE – Special Authority see SA1161 below – Retail pharmacy a) Varenicline will not be funded Close Control in amounts less than 2 weeks of treatment. b) A maximum of 3 months’ varenicline will be subsidised on each Special Authority approval. Tab 1 mg ...........................................................................................67.74 28 Champix 135.48 56 Champix Tab 0.5 mg × 11 and 1 mg × 14 ......................................................60.48 25 OP Champix ¾SA1161 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 5 months for applications meeting the following criteria: All of the following: 1 Short-term therapy as an aid to achieving abstinence in a patient who has indicated that they are ready to cease smoking; and 2 The patient is part of, or is about to enrol in, a comprehensive support and counselling smoking cessation programme, which includes prescriber or nurse monitoring; and 3 Either: 3.1 The patient has tried but failed to quit smoking after at least two separate trials of nicotine replacement therapy, at least one of which included the patient receiving comprehensive advice on the optimal use of nicotine replacement therapy; or 3.2 The patient has tried but failed to quit smoking using bupropion or nortriptyline; and 4 The patient has not used funded varenicline in the last 12 months; and 5 Varenicline is not to be used in combination with other pharmacological smoking cessation treatments and the patient has agreed to this; and 6 The patient is not pregnant; and 7 The patient will not be prescribed more than 3 months’ funded varenicline (see note). Renewal from any relevant practitioner. Approvals valid for 5 months for applications meeting the following criteria: All of the following: 1 Short-term therapy as an aid to achieving abstinence in a patient who has indicated that they are ready to cease smoking; and 2 The patient is part of, or is about to enrol in, a comprehensive support and counselling smoking cessation programme, which includes prescriber or nurse monitoring; and 3 The patient has not used funded varenicline in the last 12 months; and 4 Varenicline is not to be used in combination with other pharmacological smoking cessation treatments and the patient has agreed to this; and 5 The patient is not pregnant; and 6 The patient will not be prescribed more than 3 months’ funded varenicline (see note). The patient may not have had an approval in the past 12 months. Note: a maximum of 3 months’ varenicline will be subsidised on each Special Authority approval.

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

139

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Chemotherapeutic Agents Alkylating Agents

BUSULPHAN – PCT – Retail pharmacy-Specialist Tab 2 mg ...........................................................................................59.50 CARBOPLATIN – PCT only – Specialist Inj 10 mg per ml, 5 ml .......................................................................20.00 Inj 10 mg per ml, 15 ml .....................................................................22.50 Inj 10 mg per ml, 45 ml .....................................................................50.00 Inj 10 mg per ml, 100 ml .................................................................105.00 Inj 1 mg for ECP .................................................................................0.15 CARMUSTINE – PCT only – Specialist Inj 100 mg .......................................................................................204.13 Inj 100 mg for ECP .........................................................................204.13 CHLORAMBUCIL – PCT – Retail pharmacy-Specialist Tab 2 mg ...........................................................................................22.35 CISPLATIN – PCT only – Specialist Inj 1 mg per ml, 50 ml .......................................................................15.00 19.00 Inj 1 mg per ml, 100 ml .....................................................................21.00 38.00 Inj 1 mg for ECP .................................................................................0.27 CYCLOPHOSPHAMIDE Tab 50 mg – PCT – Retail pharmacy-Specialist..............................25.71 Inj 1 g – PCT – Retail pharmacy-Specialist.....................................26.70 127.80 Inj 2 g – PCT only – Specialist.........................................................56.90 Inj 1 mg for ECP – PCT only – Specialist ..........................................0.03 IFOSFAMIDE – PCT only – Specialist Inj 1 g ................................................................................................96.00 Inj 2 g ..............................................................................................180.00 Inj 1 mg for ECP .................................................................................0.10 LOMUSTINE – PCT only – Specialist Cap 10 mg ......................................................................................132.59 Cap 40 mg ......................................................................................399.15 MELPHALAN Tab 2 mg – PCT – Retail pharmacy-Specialist................................31.31 Inj 50 mg – PCT only – Specialist....................................................52.15 100 1 1 1 1 1 mg 1 100 mg OP 25 1 1 1 mg 50 1 6 1 1 mg 1 1 1 mg 20 20 25 1

Myleran Carboplatin Ebewe Carboplatin Ebewe Carboplatin Ebewe Carboplatin Ebewe Baxter BiCNU Baxter Leukeran FC Cisplatin Ebewe Mayne Cisplatin Ebewe Mayne Baxter Cycloblastin Endoxan Cytoxan Endoxan Baxter Holoxan Holoxan Baxter CeeNU CeeNU Alkeran Alkeran Oxaliplatin Ebewe Eloxatin Oxaliplatin Ebewe Eloxatin Baxter

OXALIPLATIN – PCT only – Specialist – Special Authority see SA0900 on the next page Inj 50 mg ...........................................................................................55.00 1 200.00 Inj 100 mg .......................................................................................110.00 1 400.00 1 mg Inj 1 mg for ECP .................................................................................1.20

140

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA0900 Special Authority for Subsidy Initial application only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has metastatic colorectal cancer; and 1.2 To be used for ﬁrst or second line use as part of a combination chemotherapy regimen; or 2 Both: 2.1 The patient has stage III (Duke’s C) colorectal* cancer; and 2.2 Adjuvant oxaliplatin to be given in combination with a ﬂuoropyrimidine (ﬂuorouracil or capecitabine). Renewal only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 The patient requires continued therapy; or 2 The tumour has relapsed and requires re-treatment. Note: Indications marked with * are Unapproved Indications, oxaliplatin is indicated for adjuvant treatment of stage III (Duke’s C) colon cancer after complete resection of the primary tumour. THIOTEPA – PCT only – Specialist Inj 15 mg ...........................................................................................CBS 1 Bedford S29

Antimetabolites

CALCIUM FOLINATE Tab 15 mg – PCT – Retail pharmacy-Specialist..............................82.45 Inj 3 mg per ml, 1 ml – PCT – Retail pharmacy-Specialist ..............17.10 Inj 50 mg – PCT – Retail pharmacy-Specialist................................24.50 Inj 100 mg – PCT only – Specialist....................................................9.75 Inj 300 mg – PCT only – Specialist..................................................30.00 Inj 1 g – PCT only – Specialist.........................................................90.00 Inj 1 mg for ECP – PCT only – Specialist ..........................................0.10 10 5 5 1 1 1 1 mg

DBL Leucovorin

Calcium

Mayne Calcium Folinate

Ebewe

Calcium Folinate

Ebewe

Calcium Folinate

Ebewe

Calcium Folinate

Ebewe

Baxter Xeloda Xeloda

CAPECITABINE – Retail pharmacy-Specialist – Special Authority see SA1049 below Tab 150 mg .....................................................................................115.00 60 Tab 500 mg .....................................................................................705.00 120

¾SA1049 Special Authority for Subsidy Initial application only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Any of the following: 1 The patient has advanced gastrointestinal malignancy; or 2 The patient has metastatic breast cancer; or 3 The patient has stage III (Duke’s stage C) colorectal*# cancer and undergone surgery; or 4 Both: 4.1 The patient has stage II (Dukes’ stage B) colorectal* cancer and has undergone surgery; and 4.2 Any of the following: 4.2.1 The patient has stage T4 disease; or continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

141

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 4.2.2 The patient has vascular invasion; or 4.2.3 Fewer than 10 lymph nodes were examined at resection; or 5 All of the following: 5.1 The patient has locally advanced (clinically or radiologically staged T3/T4: N0,1,2) rectal cancer; and 5.2 Surgery is planned; and 5.3 Capecitabine to be given prior to surgery (neoadjuvant); and 5.4 Capecitabine to be given at a maximum dose of 825 mg/m2 twice daily in combination with radiation therapy for a maximum of 6 weeks; or 6 Both: 6.1 The patient has poor venous access or needle phobia*; and 6.2 The patient requires a substitute for single agent ﬂuoropyrimidine*. Note: Indications marked with * are Unapproved Indications, # capecitabine is approved for stage III (Duke’s stage C) colon cancer. Renewal only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 The patient requires continued therapy; or 2 The tumour has relapsed and requires re-treatment. CLADRIBINE – PCT only – Specialist Inj 2 mg per ml, 5 ml .......................................................................873.00 1 Litak S29 Inj 1 mg per ml, 10 ml ..................................................................5,249.72 7 Leustatin Inj 10 mg for ECP ...........................................................................749.96 10 mg OP Baxter CYTARABINE Inj 100 mg – PCT – Retail pharmacy-Specialist..............................76.00 80.00 Inj 500 mg – PCT – Retail pharmacy-Specialist..............................18.15 95.36 Inj 1 g – PCT – Retail pharmacy-Specialist.....................................37.00 42.65 Inj 2 g – PCT – Retail pharmacy-Specialist.....................................31.00 34.47 Inj 1 mg for ECP – PCT only – Specialist ..........................................0.27 Inj 100 mg intrathecal syringe for ECP – PCT only – Specialist .........15.20 FLUDARABINE PHOSPHATE – PCT only – Specialist Tab 10 mg .......................................................................................867.00 Inj 50 mg .........................................................................................525.00 1,430.00 Inj 50 mg for ECP ...........................................................................105.00 FLUOROURACIL SODIUM Inj 50 mg per ml, 10 ml – PCT only – Specialist..............................26.25 Inj 50 mg per ml, 20 ml – PCT only – Specialist................................7.50 Inj 25 mg per ml, 100 ml – PCT only – Specialist............................13.55 Inj 50 mg per ml, 50 ml – PCT only – Specialist..............................18.00 Inj 50 mg per ml, 100 ml – PCT only – Specialist............................34.50 Inj 1 mg for ECP – PCT only – Specialist ..........................................0.77 5 1 5 1 1 10 mg 100 mg OP 20 5 50 mg OP 5 1 1 1 1 100 mg

Pﬁzer Mayne Pﬁzer Mayne Pﬁzer Mayne Pﬁzer Mayne Baxter Baxter Fludara Oral Fludarabine Ebewe Fludara Baxter Fluorouracil Ebewe Fluorouracil Ebewe Mayne Fluorouracil Ebewe Fluorouracil Ebewe Baxter

142

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

GEMCITABINE HYDROCHLORIDE – PCT only – Specialist – Special Authority see SA1087 below Inj 1 g ................................................................................................62.50 1 Gemcitabine Ebewe 349.20 Gemzar Inj 200 mg .........................................................................................12.50 1 Gemcitabine Ebewe 78.00 Gemzar Inj 1 mg for ECP .................................................................................0.07 1 mg Baxter ¾SA1087 Special Authority for Subsidy Initial application — (Hodgkin’s Disease) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: All of the following: 1 The patient has Hodgkin’s Disease*; and 2 Any of the following: 2.1 Disease has failed to respond to second line salvage chemotherapy treatment; or 2.2 Disease has relapsed following transplant; or 2.3 The patient is unsuitable for, or intolerant to, second-line salvage chemotherapy or high dose chemotherapy and transplant; and 3 Gemcitabine to be given for a maximum of 6 treatment cycles. Note: Indications marked with a * are Unapproved Indications. Initial application — (T-Cell Lymphoma) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 The patient has T-cell Lymphoma*; and 2 Gemcitabine to be given for a maximum of 6 treatment cycles. Note: Indications marked with a * are Unapproved Indications. Initial application — (Cholangiocarcinoma) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 The patient has locally advanced or metastatic, cholangiocarcinoma*; and 2 Gemcitabine to be given for a maximum of 8 treatment cycles. Notes: Cholangiocarcinoma encompasses epithelial tumours of the hepatobiliary tree, including tumours of bile ducts, ampulla of vater and gallbladder. Indications marked with a * are Unapproved Indications. Initial application — (Pancreatic Cancer) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has macroscopically resected (R0) pancreatic carcinoma*; and 1.2 Adjuvant gemcitabine to be administered for a maximum of 6 cycles; or 2 Both: 2.1 The patient has advanced pancreatic carcinoma; and 2.2 The patient is gemcitabine treatment naive. Note: Indications marked with a * are Unapproved Indications. Renewal — (Pancreatic Cancer) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: All of the following: 1 The patient has received gemcitabine for advanced pancreatic carcinoma; and 2 The patient has not received gemcitabine for adjuvant treatment pancreatic carcinoma; and 3 The patient requires continued therapy. continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

143

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . Initial application — (Other indications) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Any of the following: 1 1 The patient has non small cell lung carcinoma (stage IIIa, or above); or 2 The patient has advanced malignant mesothelioma; or 3 The patient has ovarian, fallopian tube* or primary peritoneal carcinoma*; or 4 The patient has advanced transitional cell carcinoma of the urothelial tract (locally advanced or metastatic). Note: Indications marked with a * are Unapproved Indications. Renewal — (Other indications) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 The patient requires continued therapy; or 2 The tumour has relapsed and requires re-treatment. IRINOTECAN – PCT only – Specialist – Special Authority see SA0878 below Inj 20 mg per ml, 2 ml .......................................................................41.00 1 Camptosar Irinotecan-Rex Inj 20 mg per ml, 5 ml .....................................................................100.00 1 Camptosar Irinotecan-Rex Inj 1 mg for ECP .................................................................................1.04 1 mg Baxter ¾SA0878 Special Authority for Subsidy Initial application only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 The patient has metastatic colorectal cancer; and 2 Either: 2.1 To be used for ﬁrst or second line use as part of a combination chemotherapy regimen; or 2.2 As single agent chemotherapy in ﬂuropyrimidine-relapsed disease. Renewal only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 The patient requires continued therapy; or 2 The tumour has relapsed and requires re-treatment. MERCAPTOPURINE – PCT – Retail pharmacy-Specialist Tab 50 mg .........................................................................................47.06 25 Purinethol METHOTREXATE F Tab 2.5 mg – PCT – Retail pharmacy-Specialist...............................5.22 F Tab 10 mg – PCT – Retail pharmacy-Specialist..............................40.93 F Inj 2.5 mg per ml, 2 ml – PCT – Retail pharmacy-Specialist ...........23.65 F Inj 25 mg per ml, 2 ml – PCT – Retail pharmacy-Specialist ............48.00 F Inj 25 mg per ml, 20 ml – PCT – Retail pharmacy-Specialist ..........90.00 F Inj 100 mg per ml, 10 ml – PCT – Retail pharmacy-Specialist .........25.00 F Inj 25 mg per ml, 40 ml – PCT – Retail pharmacy-Specialist ..........25.00 F Inj 100 mg per ml, 50 ml – PCT – Retail pharmacy-Specialist .........125.00 F Inj 1 mg for ECP – PCT only – Specialist ..........................................0.10 F Inj 5 mg intrathecal syringe for ECP – PCT only – Specialist............4.73 THIOGUANINE – PCT – Retail pharmacy-Specialist Tab 40 mg .........................................................................................97.16 30 50 5 5 1 1 1 1 1 mg 5 mg OP 25

Methoblastin Methoblastin Mayne Hospira Hospira Methotrexate Ebewe DBL

Methotrexate

S29

Methotrexate Ebewe Baxter Baxter Lanvis

144

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Other Cytotoxic Agents

AMSACRINE – PCT only – Specialist Inj 75 mg ...........................................................................................CBS 6

Amsidine S29

ANAGRELIDE HYDROCHLORIDE – PCT only – Specialist – Special Authority see SA0879 below Cap 0.5 mg .......................................................................................CBS 100 Agrylin S29 Teva S29 ¾SA0879 Special Authority for Subsidy Initial application only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 The patient has primary thrombocythaemia; and 2 Either: 2.1 is at high risk (previous thromboembolic disease, bleeding or platelet count >1500/ml); or 2.2 is intolerant or refractory to hydroxyurea or interferon. Renewal only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months where the treatment remains appropriate and the patient is beneﬁting from treatment. Note: It is recommended that treatment with anagrelide be initiated only on the recommendation of a haematologist. ARSENIC TRIOXIDE – PCT only – Specialist Inj 10 mg ......................................................................................4,817.00 10 AFT S29 BLEOMYCIN SULPHATE – PCT only – Specialist Inj 15,000 iu ....................................................................................120.00 Inj 1,000 iu for ECP ............................................................................9.28 BORTEZOMIB – PCT only – Specialist – Special Authority see SA1127 below Inj 1 mg ...........................................................................................540.70 Inj 3.5 mg .....................................................................................1,892.50 Inj 1 mg for ECP .............................................................................594.77 1 1,000 iu 1 1 1 mg

DBL Bleomycin

Sulfate

Baxter Velcade Velcade Baxter

¾SA1127 Special Authority for Subsidy Initial application — (Treatment naive multiple myeloma/amyloidosis) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 15 months for applications meeting the following criteria: Both: 1 Either: 1.1 The patient has treatment-naive symptomatic multiple myeloma; or 1.2 The patient has treatment-naive symptomatic systemic AL amyloidosis *; and 2 Maximum of 9 treatment cycles. Note: Indications marked with * are Unapproved Indications. Initial application — (Relapsed/refractory multiple myeloma/amyloidosis) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 8 months for applications meeting the following criteria: All of the following: 1 Either: 1.1 The patient has relapsed or refractory multiple myeloma; or 1.2 The patient has relapsed or refractory systemic AL amyloidosis *; and 2 The patient has received only one prior front line chemotherapy for multiple myeloma or amyloidosis; and 3 The patient has not had prior publicly funded treatment with bortezomib; and 4 Maximum of 4 further treatment cycles. Note: Indications marked with * are Unapproved Indications. continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

145

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . Renewal — (Relapsed/refractory multiple myeloma/amyloidosis) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 8 months for applications meeting the following criteria: Both: 1 The patient’s disease obtained at least a partial response from treatment with bortezomib at the completion of cycle 4; and 2 Maximum of 4 further treatment cycles (making a total maximum of 8 consecutive treatment cycles). Notes: Responding relapsed/refractory multiple myeloma patients should receive no more than 2 additional cycles of treatment beyond the cycle at which a conﬁrmed complete response was ﬁrst achieved. A line of therapy is considered to comprise either: a) a known therapeutic chemotherapy regimen and supportive treatments; or b) a transplant induction chemotherapy regimen, stem cell transplantation and supportive treatments. Refer to datasheet for recommended dosage and number of doses of bortezomib per treatment cycle. COLASPASE (L-ASPARAGINASE) – PCT only – Specialist Inj 10,000 iu ....................................................................................102.32 1 Leunase Inj 10,000 iu for ECP ......................................................................102.32 10,000 iu OP Baxter DACARBAZINE – PCT only – Specialist Inj 200 mg .........................................................................................48.00 Inj 200 mg for ECP ...........................................................................48.00 DACTINOMYCIN (ACTINOMYCIN D) – PCT only – Specialist Inj 0.5 mg ..........................................................................................13.52 Inj 0.5 mg for ECP ............................................................................13.52 DAUNORUBICIN – PCT only – Specialist Inj 2 mg per ml, 10 ml .....................................................................118.72 Inj 5 mg per ml, 4 ml ........................................................................99.00 Inj 20 mg for ECP ...........................................................................118.72 (Mayne Inj 5 mg per ml, 4 ml to be delisted 1 February 2012) DOCETAXEL – PCT only – Specialist Inj 20 mg ...........................................................................................48.75 460.00 Inj 80 mg .........................................................................................195.00 1,650.00 Inj 1 mg for ECP .................................................................................2.63 DOXORUBICIN – PCT only – Specialist Inj 10 mg ...........................................................................................10.00 Inj 50 mg ...........................................................................................40.00 1 200 mg OP 1 0.5 mg OP 1 1 20 mg OP

Hospira Baxter Cosmegen Baxter Pﬁzer Mayne Baxter

1 1 1 mg 1 1

Docetaxel Ebewe Taxotere Docetaxel Ebewe Taxotere Baxter Doxorubicin Ebewe DBL

Doxorubicin

S29

Inj 100 mg .........................................................................................80.00 Inj 200 mg .......................................................................................150.00 Inj 1 mg for ECP .................................................................................0.88 EPIRUBICIN – PCT only – Specialist Inj 2 mg per ml, 5 ml .........................................................................25.00 Inj 2 mg per ml, 25 ml .......................................................................87.50 Inj 2 mg per ml, 50 ml .....................................................................125.00 Inj 2 mg per ml, 100 ml ...................................................................210.00 Inj 1 mg for ECP .................................................................................1.80

1 1 1 mg 1 1 1 1 1 mg

Doxorubicin Ebewe Doxorubicin Ebewe Doxorubicin Ebewe Baxter Epirubicin Ebewe Epirubicin Ebewe Epirubicin Ebewe Epirubicin Ebewe Baxter

146

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

ETOPOSIDE Cap 50 mg – PCT – Retail pharmacy-Specialist ...........................340.73 Cap 100 mg – PCT – Retail pharmacy-Specialist .........................340.73 Inj 20 mg per ml, 5 ml – PCT – Retail pharmacy-Specialist ............25.00 612.20 Inj 1 mg for ECP – PCT only – Specialist ..........................................0.30 ETOPOSIDE PHOSPHATE – PCT only – Specialist Inj 100 mg (of etoposide base) .........................................................40.00 Inj 1 mg (of etoposide base) for ECP .................................................0.47 HYDROXYUREA – PCT – Retail pharmacy-Specialist Cap 500 mg ......................................................................................31.76 IDARUBICIN HYDROCHLORIDE – PCT only – Specialist Cap 5 mg ........................................................................................115.00 Cap 10 mg ......................................................................................144.50 Inj 5 mg ...........................................................................................170.00 Inj 10 mg .........................................................................................340.00 Inj 1 mg for ECP ...............................................................................37.74 MESNA – PCT only – Specialist Tab 400 mg .....................................................................................210.65 Tab 600 mg .....................................................................................314.40 Inj 100 mg per ml, 4 ml ...................................................................137.04 Inj 100 mg per ml, 10 ml .................................................................314.66 Inj 1 mg for ECP .................................................................................2.29 MITOMYCIN C – PCT only – Specialist Inj 5 mg .............................................................................................72.75 Inj 1 mg for ECP ...............................................................................16.13 MITOZANTRONE – PCT only – Specialist Inj 2 mg per ml, 5 ml .......................................................................110.00 Inj 2 mg per ml, 10 ml .....................................................................100.00 Inj 2 mg per ml, 12.5 ml ..................................................................407.50 Inj 1 mg for ECP .................................................................................5.65 PACLITAXEL – PCT only – Specialist Inj 30 mg .........................................................................................137.50 Inj 100 mg .........................................................................................91.67 Inj 150 mg .......................................................................................137.50

20 10 1 10 1 mg 1 1 mg 100 1 1 1 1 1 mg 50 50 15 15 100 mg 1 1 mg 1 1 1 1 mg 5 1 1

Vepesid Vepesid Mayne Vepesid Baxter Etopophos Baxter Hydrea Zavedos Zavedos Zavedos Zavedos Baxter Uromitexan Uromitexan Uromitexan Uromitexan Baxter Arrow Baxter Mitozantrone Ebewe Mitozantrone Ebewe Onkotrone Baxter Paclitaxel Ebewe Paclitaxel Actavis Paclitaxel Ebewe Anzatax Paclitaxel Actavis Paclitaxel Ebewe Anzatax Paclitaxel Actavis Paclitaxel Ebewe Paclitaxel Ebewe Baxter Nipent S29 Natulan S29

Inj 300 mg .......................................................................................275.00

Inj 600 mg .......................................................................................550.00 Inj 1 mg for ECP .................................................................................1.02 PENTOSTATIN (DEOXYCOFORMYCIN) – PCT only – Specialist Inj 10 mg ...........................................................................................CBS PROCARBAZINE HYDROCHLORIDE – PCT only – Specialist Cap 50 mg ......................................................................................225.00

1 1 mg 1 50

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

147

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

TEMOZOLOMIDE – Special Authority see SA1063 below – Retail pharmacy Cap 5 mg ..........................................................................................50.00 Cap 20 mg ......................................................................................170.00 Cap 100 mg ....................................................................................840.00 Cap 250 mg .................................................................................2,100.00

5 5 5 5

Temodal Temodal Temodal Temodal

¾SA1063 Special Authority for Subsidy Initial application only from a relevant specialist. Approvals valid for 10 months for applications meeting the following criteria: All of the following: 1 Either: 1.1 Patient has newly diagnosed glioblastoma multiforme; or 1.2 Patient has newly diagnosed anaplastic astrocytoma*; and 2 Temozolomide is to be (or has been) given concomitantly with radiotherapy; and 3 Following concomitant treatment temozolomide is to be used for a maximum of six cycles of 5 days treatment, at a maximum dose of 200 mg/m2 . Notes: Indication marked with a * is an Unapproved Indication. Temozolomide is not subsidised for the treatment of relapsed glioblastoma multiforme. Reapplications will not be approved. Studies of temozolomide show that its beneﬁt is predominantly in those patients with a good performance status (WHO grade 0 or 1 or Karnofsky score >80), and in patients who have had at least a partial resection of the tumour. THALIDOMIDE – PCT only – Specialist – Special Authority see SA1124 below Cap 50 mg ......................................................................................504.00 28 Thalomid Cap 100 mg .................................................................................1,008.00 28 Thalomid ¾SA1124 Special Authority for Subsidy Initial application only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 The patient has multiple myeloma; or 2 The patient has systemic AL amyloidosis*. Renewal only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid without further renewal unless notiﬁed where the patient has obtained a response from treatment during the initial approval period. Notes: Prescription must be written by a registered prescriber in the thalidomide risk management programme operated by the supplier. Maximum dose of 400 mg daily as monotherapy or in a combination therapy regimen. Indication marked with * is an Unapproved Indication. TRETINOIN Cap 10 mg – PCT – Retail pharmacy-Specialist ...........................435.90 100 Vesanoid VINBLASTINE SULPHATE Inj 10 mg – PCT – Retail pharmacy-Specialist................................27.50 137.50 Inj 1 mg for ECP – PCT only – Specialist ..........................................3.05 VINCRISTINE SULPHATE Inj 1 mg per ml, 1 ml – PCT – Retail pharmacy-Specialist ............108.00 Inj 1 mg per ml, 2 ml – PCT – Retail pharmacy-Specialist ............116.00 Inj 1 mg for ECP – PCT only – Specialist ........................................15.77 1 5 1 mg 5 5 1 mg

Mayne Mayne Baxter Hospira Hospira Baxter Navelbine Vinorelbine Ebewe Navelbine Vinorelbine Ebewe Baxter

VINORELBINE – PCT only – Specialist – Special Authority see SA1013 on the next page Inj 10 mg per ml, 1 ml .......................................................................24.00 1 42.00 Inj 10 mg per ml, 5 ml .....................................................................120.00 1 210.00 Inj 1 mg for ECP .................................................................................2.71 1 mg

fully subsidised [HP4] refer page 9

148

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

¾SA1013 Special Authority for Subsidy Initial application — (Hodgkin’s Disease) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: All of the following: 1 The patient has Hodgkin’s Disease*; and 2 Any of the following: 2.1 Disease has failed to respond to second-line salvage chemotherapy treatment; or 2.2 Disease has relapsed following transplant; or 2.3 The patient is unsuitable for, or intolerant to, second-line salvage chemotherapy or high dose chemotherapy and transplant; and 3 Vinorelbine to be given for a maximum of 6 treatment cycles. Initial application — (T-Cell Lymphoma) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 The patient has T-cell Lymphoma*; and 2 Vinorelbine to be given for a maximum of 6 treatment cycles. Initial application — (Other indications) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Any of the following: 1 The patient has metastatic breast cancer; or 2 The patient has non-small cell lung cancer (stage IIIa, or above); or 3 All of the following: 3.1 The patient has stage IB-IIIA non-small cell lung cancer; and 3.2 Vinorelbine is to be given as adjuvant treatment in combination with cisplatin; and 3.3 The patient has good performance status (WHO/ECOG grade 0-1). Renewal — (Other indications) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 The patient requires continued therapy; or 2 The tumour has relapsed and requires re-treatment. Note: Indications marked with a * are Unapproved Indications.

Protein-tyrosine Kinase Inhibitors

DASATINIB – Special Authority see SA0976 below Tab 20 mg ....................................................................................3,774.06 Tab 50 mg ....................................................................................6,214.20 Tab 70 mg ....................................................................................7,692.58 Tab 100 mg ..................................................................................6,214.20 60 60 60 30

Sprycel Sprycel Sprycel Sprycel

¾SA0976 Special Authority for Subsidy Special Authority approved by the CML/GIST Co-ordinator Notes: Application details may be obtained from PHARMAC’s website http://www.pharmac.govt.nz, and prescriptions should be sent to: The CML/GIST Co-ordinator Phone: (04) 460 4990 PHARMAC Facsimile: (04) 916 7571 PO Box 10 254 Email: mary.chesterﬁeld@pharmac.govt.nz Wellington Special Authority criteria for CML - access by application a) Funded for patients with diagnosis (conﬁrmed by a haematologist) of a chronic myeloid leukaemia (CML) in blast crisis, accelerated phase, or in chronic phase. continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

149

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . b) Maximum dose of 140 mg/day for accelerated or blast phase, and 100 mg/day for chronic phase CML. c) Subsidised for use as monotherapy only. d) Initial approvals valid seven months. e) Subsequent approval(s) are granted on application and are valid for six months. The ﬁrst reapplication (after seven months) should provide details of the haematological response. The third reapplication should provide details of the cytogenetic response after 14-18 months from initiating therapy. All other reapplications should provide details of haematological response, and cytogenetic response if such data is available. Applications to be made and subsequent prescriptions can be written by a haematologist or an oncologist. Note: Dasatinib is indicated for the treatment of adults with chronic, accelerated or blast phase CML with resistance or intolerance to prior therapy including imatinib. Guideline on discontinuation of treatment for patients with CML a) Prescribers should consider discontinuation of treatment if, after 6 months from initiating therapy, a patient did not obtain a haematological response as deﬁned as any one of the following three levels of response: 1) complete haematologic response (as characterised by an absolute neutrophil count (ANC) > 1.5 × 109 /L, platelets > 100 × 109 /L, absence of peripheral blood (PB) blasts, bone marrow (BM) blasts < 5% (or FISH Ph+ 0-35% metaphases), and absence of extramedullary disease); or 2) no evidence of leukaemia (as characterised by an absolute neutrophil count (ANC) > 1.0 × 109 /L, platelets > 20 × 109 /L, absence of peripheral blood (PB) blasts, bone marrow (BM) blasts < 5% (or FISH Ph+ 0-35% metaphases), and absence of extramedullary disease); or 3) return to chronic phase (as characterised by BM and PB blasts < 15%, BM and PB blasts and promyelocytes < 30%, PB basophils < 20% and absence of extramedullary disease other than spleen and liver). b) Prescribers should consider discontinuation of treatment if, after 18 months from initiating therapy, a patient did not obtain a major cytogenetic response deﬁned as 0-35% Ph+ metaphases. ERLOTINIB HYDROCHLORIDE – Retail pharmacy-Specialist – Special Authority see SA1044 below Tab 100 mg ..................................................................................3,100.00 30 Tarceva Tab 150 mg ..................................................................................3,950.00 30 Tarceva ¾SA1044 Special Authority for Subsidy Initial application only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 4 months for applications meeting the following criteria: All of the following: 1 Patient has advanced, unresectable, Non Small Cell Lung Cancer (NSCLC); and 2 Patient has documented disease progression following treatment with ﬁrst line platinum based chemotherapy; and 3 Erlotinib is to be given for a maximum of 3 months. Renewal only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 6 months where radiological assessment (preferably including CT scan) indicates NSCLC has not progressed. IMATINIB MESYLATE – Special Authority see SA0643 below Tab 100 mg ..................................................................................2,400.00 60 Glivec

¾SA0643 Special Authority for Subsidy Special Authority approved by the CML/GIST Co-ordinator Notes: Application details may be obtained from PHARMAC’s website http://www.pharmac.govt.nz, and prescriptions should be sent to: The CML/GIST Co-ordinator Phone: (04) 460 4990 PHARMAC Facsimile: (04) 916 7571 PO Box 10 254 Email: mary.chesterﬁeld@pharmac.govt.nz Wellington Special Authority criteria for CML – access by application continued. . .

150

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . a) Funded for patients with diagnosis (conﬁrmed by a haematologist) of a chronic myeloid leukaemia (CML) in blast crisis, accelerated phase, or in chronic phase. b) Maximum dose of 600 mg/day for accelerated or blast phase, and 400 mg/day for chronic phase CML. c) Subsidised for use as monotherapy only. d) Initial approvals valid seven months. e) Subsequent approval(s) are granted on application and are valid for six months. The ﬁrst reapplication (after seven months) should provide details of the haematological response. The third reapplication should provide details of the cytogenetic response after 14-18 months from initiating therapy. All other reapplications should provide details of haematological response, and cytogenetic response if such data is available. Applications to be made and subsequent prescriptions can be written by a haematologist or an oncologist. Guideline on discontinuation of treatment for patients with CML a) Prescribers should consider discontinuation of treatment if after 6 months from initiating therapy a patient did not obtain a haematological response as deﬁned as any one of the following three levels of response: 1) complete haematologic response (as characterised by an absolute neutrophil count (ANC) > 1.5 × 109 /L, platelets > 100 × 109 /L, absence of peripheral blood (PB) blasts, bone marrow (BM) blasts < 5% (or FISH Ph+ 0-35% metaphases), and absence of extramedullary disease); or 2) no evidence of leukaemia (as characterised by an absolute neutrophil count (ANC) > 1.0 × 109 /L, platelets > 20 × 109 /L, absence of peripheral blood (PB) blasts, bone marrow (BM) blasts < 5% (or FISH Ph+ 0-35% metaphases), and absence of extramedullary disease); or 3) return to chronic phase (as characterised by BM and PB blasts < 15%, BM and PB blasts and promyelocytes < 30%, PB basophils < 20% and absence of extramedullary disease other than spleen and liver). b) Prescribers should consider discontinuation of treatment if after 18 months from initiating therapy a patient did not obtain a major cytogenetic response deﬁned as 0-35% Ph+ metaphases. Special Authority criteria for GIST – access by application a) Funded for patients: 1) with a diagnosis (conﬁrmed by an oncologist) of unresectable and/or metastatic malignant gastrointestinal stromal tumour (GIST); and 2) who have immunohistochemical documentation of c-kit (CD117) expression by the tumour. b) Maximum dose of 400 mg/day. c) Applications to be made and subsequent prescriptions can be written by an oncologist. d) Initial and subsequent applications are valid for one year. The re-application criterion is an adequate clinical response to the treatment with imatinib (prescriber determined). SUNITINIB – Special Authority see SA1162 below – Retail pharmacy Cap 12.5 mg ................................................................................2,315.38 28 Sutent Cap 25 mg ...................................................................................4,630.77 28 Sutent Cap 50 mg ...................................................................................9,261.54 28 Sutent ¾SA1162 Special Authority for Subsidy Initial application only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 3 months for applications meeting the following criteria: All of the following: 1 The patient has metastatic renal cell carcinoma; and 2 Either: 2.1 The patient is sunitinib treatment naive; or 2.2 The patient received sunitinib prior to 1 November 2010 and disease has not progressed; and 3 The patient has good performance status (WHO/ECOG grade 0-2); and 4 The disease is of predominant clear cell histology; and The patient has intermediate or poor prognosis deﬁned as: 5 Any of the following: continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

151

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 5.1 Lactate dehydrogenase level > 1.5 times upper limit of normal; or 5.2 Haemoglobin level < lower limit of normal; or 5.3 Corrected serum calcium level > 10 mg/dL (2.5 mmol/L); or 5.4 Interval of < 1 year from original diagnosis to the start of systemic therapy; or 5.5 Karnofsky performance score of ≤ 70; or 5.6 ≥ 2 sites of organ metastasis; and 6 Sunitinib to be used for a maximum of 2 cycles. Renewal only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 3 months for applications meeting the following criteria: Both: 1 No evidence of disease progression; and 2 The treatment remains appropriate and the patient is beneﬁting from treatment. Notes: Sunitinib treatment should be stopped if disease progresses. Poor prognosis patients are deﬁned as having at least 3 of criteria 5.1-5.6. Intermediate prognosis patients are deﬁned as having 1 or 2 of criteria 5.1-5.6

Endocrine Therapy

For GnRH ANALOGUES – refer to HORMONE PREPARATIONS, Trophic Hormones, page 77 BICALUTAMIDE – Special Authority see SA0941 below – Retail pharmacy Tab 50 mg .........................................................................................10.00 28 10.71 30 (Bicalox Tab 50 mg to be delisted 1 February 2012)

Bicalaccord Bicalox

¾SA0941 Special Authority for Subsidy Initial application from any medical practitioner. Approvals valid without further renewal unless notiﬁed where the patient has advanced prostate cancer. FLUTAMIDE – Retail pharmacy-Specialist Tab 250 mg .......................................................................................55.00 100 Flutamin MEGESTROL ACETATE – Retail pharmacy-Specialist Tab 160 mg .......................................................................................57.92 30

Apo-Megestrol Megace

OCTREOTIDE (SOMATOSTATIN ANALOGUE) – Special Authority see SA1016 below – Retail pharmacy Inj 50 µg per ml, 1 ml ........................................................................25.65 5 Hospira 43.50 Sandostatin Inj 100 µg per ml, 1 ml ......................................................................48.50 5 Hospira 81.00 Sandostatin Inj 500 µg per ml, 1 ml ....................................................................175.00 5 Hospira 399.00 Sandostatin Inj LAR 10 mg preﬁlled syringe ...................................................1,772.50 1 Sandostatin LAR Inj LAR 20 mg preﬁlled syringe ...................................................2,358.75 1 Sandostatin LAR Inj LAR 30 mg preﬁlled syringe ...................................................2,951.25 1 Sandostatin LAR ¾SA1016 Special Authority for Subsidy Initial application — (Malignant Bowel Obstruction) from any relevant practitioner. Approvals valid for 2 months for applications meeting the following criteria: All of the following: 1 The patient has nausea* and vomiting* due to malignant bowel obstruction*; and 2 Treatment with antiemetics, rehydration, antimuscarinic agents, corticosteroids and analgesics for at least 48 hours has failed; and continued. . .

152

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 3 Octreotide to be given at a maximum dose 1500 µg daily for up to 4 weeks. Note: Indications marked with * are Unapproved Indications. Renewal — (Malignant Bowel Obstruction) from any relevant practitioner. Approvals valid for 3 months where the treatment remains appropriate and the patient is beneﬁting from treatment. Initial application — (Acromegaly) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 3 months for applications meeting the following criteria: Both: 1 The patient has acromegaly; and 2 Any of the following: 2.1 Treatment with surgery, radiotherapy and a dopamine agonist has failed; or 2.2 Treatment with octreotide is for an interim period while awaiting the effects of radiotherapy and a dopamine agonist has failed; or 2.3 The patient is unwilling, or unable, to undergo surgery and/or radiotherapy. Renewal — (Acromegaly) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 2 years for applications meeting the following criteria: Both: 1 IGF1 levels have decreased since starting octreotide; and 2 The treatment remains appropriate and the patient is beneﬁting from treatment. Note: In patients with Acromegaly octreotide treatment should be discontinued if IGF1 levels have not decreased after 3 months treatment. In patients treated with radiotherapy octreotide treatment should be withdrawn every 2 years, for 1 month, for assessment of remission. Octreotide treatment should be stopped where there is biochemical evidence of remission (normal IGF1 levels) following octreotide treatment withdrawal for at least 4 weeks Initial application — (Other Indications) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 2 years for applications meeting the following criteria: Any of the following: 1 VIPomas and Glucagonomas - for patients who are seriously ill in order to improve their clinical state prior to deﬁnitive surgery; or 2 Both: 2.1 Gastrinoma; and 2.2 Either: 2.2.1 Patient has failed surgery; or 2.2.2 Patient in metastatic disease after H2 antagonists (or proton pump inhibitors) have failed; or 3 Both: 3.1 Insulinomas; and 3.2 Surgery is contraindicated or has failed; or 4 For pre-operative control of hypoglycaemia and for maintenance therapy; or 5 Both: 5.1 Carcinoid syndrome (diagnosed by tissue pathology and/or urinary 5HIAA analysis); and 5.2 Disabling symptoms not controlled by maximal medical therapy. Note: The use of octreotide in patients with ﬁstulae, oesophageal varices, miscellaneous diarrhoea and hypotension will not be funded as a Special Authority item Renewal — (Other Indications) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment. TAMOXIFEN CITRATE F Tab 10 mg .........................................................................................10.80 100 Genox F Tab 20 mg ...........................................................................................8.75 100 Genox

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

153

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Aromatase Inhibitors

ANASTROZOLE Tab 1 mg ...........................................................................................26.55 30

Aremed Arimidex DP-Anastrozole Aromasin Letara

EXEMESTANE Tab 25 mg .........................................................................................22.57 LETROZOLE Tab 2.5 mg ........................................................................................26.55

30 30

Immunosuppressants Cytotoxic Immunosuppressants

AZATHIOPRINE – Retail pharmacy-Specialist F Tab 50 mg – For azathioprine oral liquid formulation refer, page 172 ....................................................................................18.45 F Inj 50 mg ...........................................................................................60.00

100 1

Imuprine Imuran

MYCOPHENOLATE MOFETIL – Special Authority see SA1041 below – Retail pharmacy Dispensing pharmacy should check which brand to dispense with the prescriber if prescribed generically. Tab 500 mg .......................................................................................60.00 50 Ceptolate 70.00 Cellcept 85.00 Myaccord Cap 250 mg ......................................................................................30.00 50 Ceptolate 70.00 100 Cellcept 85.00 Myaccord Powder for oral liq 1 g per 5 ml – Subsidy by endorsement ............285.00 165 ml OP Cellcept Mycophenolate powder for oral liquid is subsidised only for patients unable to swallow tablets and capsules, and when the prescription is endorsed accordingly. ¾SA1041 Special Authority for Subsidy Initial application only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Either: 1 Transplant recipient; or 2 Both: Patients with diseases where 2.1 Steroids and azathioprine have been trialled and discontinued because of unacceptable side effects or inadequate clinical response; and 2.2 Either: Patients with diseases where 2.2.1 Cyclophosphamide has been trialled and discontinued because of unacceptable side effects or inadequate clinical response; or 2.2.2 Cyclophosphamide treatment is contraindicated.

Immune Modulators

ANTITHYMOCYTE GLOBULIN (EQUINE) – PCT only – Specialist Inj 50 mg per ml, 5 ml ..................................................................2,137.50 5

ATGAM

154

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

BACILLUS CALMETTE-GUERIN (BCG) VACCINE – PCT only – Specialist Subsidised only for bladder cancer. Inj 2-8 × 100 million CFU ...............................................................187.37 RITUXIMAB – PCT only – Specialist – Special Authority see SA1152 below Inj 100 mg per 10 ml vial .............................................................1,075.50 Inj 500 mg per 50 ml vial .............................................................2,688.30 Inj 1 mg for ECP .................................................................................5.64

1 2 1 1 mg

OncoTICE Mabthera Mabthera Baxter

¾SA1152 Special Authority for Subsidy Initial application — (Post-transplant) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 The patient has B-cell post-transplant lymphoproliferative disorder*; and 2 To be used for a maximum of 8 treatment cycles. Note: Indications marked with * are Unapproved Indications. Initial application — (Indolent, Low-grade lymphomas) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 9 months for applications meeting the following criteria: Either: 1 Both: 1.1 The patient has indolent low grade NHL with relapsed disease following prior chemotherapy; and 1.2 To be used for a maximum of 6 treatment cycles; or 2 Both: 2.1 The patient has indolent, low grade lymphoma requiring ﬁrst-line systemic chemotherapy; and 2.2 To be used for a maximum of 6 treatment cycles. Note: ’Indolent, low-grade lymphomas’ includes follicular, mantle, marginal zone and lymphoplasmacytic/Waldenstrom macroglobulinaemia. Initial application — (Aggressive CD20 positive NHL) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Either: 1 All of the following: 1.1 The patient has treatment naive aggressive CD20 positive NHL; and 1.2 To be used with a multi-agent chemotherapy regimen given with curative intent; and 1.3 To be used for a maximum of 8 treatment cycles; or 2 Both: 2.1 The patient has aggressive CD20 positive NHL with relapsed disease following prior chemotherapy; and 2.2 To be used for a maximum of 6 treatment cycles. Note: ’Aggressive CD20 positive NHL’ includes large B-cell lymphoma and Burkitt’s lymphoma/leukaemia Initial application — (Chronic Lymphocytic Leukaemia) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: All of the following: 1 The patient has progressive Binet stage A, B or C chronic lymphocytic leukaemia (CLL) requiring treatment; and 2 The patient is rituximab treatment naive; and 3 Either: 3.1 The patient is chemotherapy treatment naive; or 3.2 Both: 3.2.1 The patient’s disease has relapsed following no more than three prior lines of chemotherapy treatment; and 3.2.2 The patient has had a treatment-free interval of 12 months or more if previously treated with ﬂudarabine and cyclophosphamide chemotherapy; and 4 The patient has good performance status; and 5 The patient has good renal function (creatinine clearance ≥ 30 ml/min); and continued. . .

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

155

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 6 The patient does not have chromosome 17p deletion CLL; and 7 Rituximab to be administered in combination with ﬂudarabine and cyclophosphamide for a maximum of 6 treatment cycles; and 8 It is planned that the patient receives full dose ﬂudarabine and cyclophosphamide (orally or dose equivalent intravenous administration). Note: ’Chronic lymphocytic leukaemia (CLL)’ includes small lymphocytic lymphoma. A line of chemotherapy treatment is considered to comprise a known standard therapeutic chemotherapy regimen and supportive treatments. ’Good performance status’ means ECOG score of 0-1, however, in patients temporarily debilitated by their CLL disease symptoms a higher ECOG (2 or 3) is acceptable where treatment with rituximab is expected to improve symptoms and improve ECOG score to <2. Renewal — (Post-transplant) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 9 months for applications meeting the following criteria: All of the following: 1 The patient has had a rituximab treatment-free interval of 12 months or more; and 2 The patient has B-cell post-transplant lymphoproliferative disorder*; and 3 To be used for no more than 6 treatment cycles. Note: Indications marked with * are Unapproved Indications. Renewal — (Indolent, Low-grade lymphomas) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 9 months for applications meeting the following criteria: All of the following: 1 The patient has had a rituximab treatment-free interval of 12 months or more; and 2 The patient has indolent, low-grade NHL with relapsed disease following prior chemotherapy; and 3 To be used for no more than 6 treatment cycles. Note: ’Indolent, low-grade lymphomas’ includes follicular, mantle, marginal zone and lymphoplasmacytic/Waldenstrom macroglobulinaemia. Renewal — (Aggressive CD20 positive NHL) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: All of the following: 1 The patient has had a rituximab treatment-free interval of 12 months or more; and 2 The patient has relapsed refractory/aggressive CD20 positive NHL; and 3 To be used with a multi-agent chemotherapy regimen given with curative intent; and 4 To be used for a maximum of 4 treatment cycles. Note: ’Aggressive CD20 positive NHL’ includes large B-cell lymphoma and Burkitt’s lymphoma/leukaemia TRASTUZUMAB – PCT only – Specialist – Special Authority see SA1163 below Inj 150 mg vial .............................................................................1,350.00 1 Herceptin Inj 440 mg vial .............................................................................3,875.00 1 Herceptin Inj 1 mg for ECP .................................................................................9.36 1 mg Baxter ¾SA1163 Special Authority for Subsidy Initial application — (metastatic breast cancer) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 The patient has metastatic breast cancer expressing HER-2 IHC 3+ or FISH+ (including FISH or other current technology); and 2 Trastuzumab to be discontinued at disease progression. Renewal — (metastatic breast cancer) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 The patient has metastatic breast cancer expressing HER-2 IHC 3+ or ISH+ (including FISH or other current technology); and continued. . .

156

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 2 The cancer has not progressed at any time point during the previous 12 months whilst on trastuzumab. Initial application — (early breast cancer) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 15 months for applications meeting the following criteria: All of the following: 1 The patient has early breast cancer expressing HER 2 IHC 3+ or ISH + (including FISH or other current technology); and 2 Maximum cumulative dose of 106 mg/kg (12 months’ treatment); and 3 Any of the following: 3.1 9 weeks’ concurrent treatment with adjuvant chemotherapy is planned; or 3.2 12 months’ concurrent treatment with adjuvant chemotherapy is planned; or 3.3 12 months’ sequential treatment following adjuvant chemotherapy is planned; or 3.4 Other treatment regimen, in association with adjuvant chemotherapy, is planned. Renewal — (early breast cancer*) only from a relevant specialist or medical practitioner on the recommendation of a relevant specialist. Approvals valid for 12 months for applications meeting the following criteria: Both: 1 The patient has metastatic breast cancer expressing HER-2 IHC 3+ or ISH+ (including FISH or other current technology); and 2 Either: 2.1 Both: 2.1.1 The patient received prior adjuvant trastuzumab treatment for early breast cancer; and 2.1.2 Trastuzumab to be discontinued at disease progression; or 2.2 The cancer has not progressed at any time point during the previous 12 months whilst on trastuzumab. Note: *For patients with relapsed HER-2 positive disease who have previously received adjuvant trastuzumab for early breast cancer.

Other Immunosuppressants

CYCLOSPORIN Cap 25 mg ........................................................................................59.50 Cap 50 mg ......................................................................................118.54 Cap 100 mg ....................................................................................237.08 Oral liq 100 mg per ml ....................................................................264.17 SIROLIMUS – Special Authority see SA0866 below – Retail pharmacy Tab 1 mg .........................................................................................813.00 Tab 2 mg ......................................................................................1,626.00 Oral liq 1 mg per ml ........................................................................487.80 50 50 50 50 ml OP 100 100 60 ml OP

Neoral Neoral Neoral Neoral Rapamune Rapamune Rapamune

¾SA0866 Special Authority for Subsidy Initial application from any medical practitioner. Approvals valid without further renewal unless notiﬁed where the drug is to be used for rescue therapy for an organ transplant recipient. Notes: Rescue therapy deﬁned as unresponsive to calcineurin inhibitor treatment as deﬁned by refractory rejection; or intolerant to calcineurin inhibitor treatment due to any of the following: G GFR<30 ml/min; or G Rapidly progressive transplant vasculopathy; or G Rapidly progressive obstructive bronchiolitis; or G HUS or TTP; or G Leukoencepthalopathy; or G Signiﬁcant malignant disease

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

157

ONCOLOGY AGENTS AND IMMUNOSUPPRESSANTS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

TACROLIMUS – Special Authority see SA0669 below – Retail pharmacy Cap 0.5 mg .....................................................................................214.00 Cap 1 mg ........................................................................................428.00 Cap 5 mg – For tacrolimus oral liquid formulation refer, page 172 ........................................................................................ 1,070.00

100 100 50

Prograf Prograf Prograf

¾SA0669 Special Authority for Subsidy Initial application only from a relevant specialist. Approvals valid without further renewal unless notiﬁed where the patient is an organ transplant recipient. Note: Subsidy applies for either primary or rescue therapy.

158

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

RESPIRATORY SYSTEM AND ALLERGIES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Antiallergy Preparations

BEE VENOM ALLERGY TREATMENT – Special Authority see SA0053 below – Retail pharmacy Maintenance kit - 6 vials 120 µg freeze dried venom, 6 diluent 1.8 ml ....................................................................................... 285.00 1 OP Albay Treatment kit - 1 vial 550 µg freeze dried venom, 1 diluent 9 ml, 3 diluent 1.8 ml ............................................................... 285.00 1 OP Albay ¾SA0053 Special Authority for Subsidy Initial application only from a relevant specialist. Approvals valid for 2 years for applications meeting the following criteria: Both: 1 RAST or skin test positive; and 2 Patient has had severe generalised reaction to the sensitising agent. Renewal only from a relevant specialist. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment. WASP VENOM ALLERGY TREATMENT – Special Authority see SA0053 below – Retail pharmacy Treatment kit (Paper wasp venom) - 1 vial 550 µg freeze dried polister venom, 1 diluent 9 ml, 1 diluent 1.8 ml ....................... 285.00 1 OP Albay Treatment kit (Yellow jacket venom) - 1 vial 550 µg freeze dried vespula venom, 1 diluent 9 ml, 1 diluent 1.8 ml .............. 285.00 1 OP Albay ¾SA0053 Special Authority for Subsidy Initial application only from a relevant specialist. Approvals valid for 2 years for applications meeting the following criteria: Both: 1 RAST or skin test positive; and 2 Patient has had severe generalised reaction to the sensitising agent. Renewal only from a relevant specialist. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment.

Antihistamines

CETIRIZINE HYDROCHLORIDE F Tab 10 mg ...........................................................................................1.59 F‡ Oral liq 1 mg per ml ............................................................................3.52 CHLORPHENIRAMINE MALEATE F‡ Oral liq 2 mg per 5 ml .........................................................................8.06 DEXTROCHLORPHENIRAMINE MALEATE F Tab 2 mg .............................................................................................1.01 (4.93) 2.02 (7.99) F‡ Oral liq 2 mg per 5 ml .........................................................................1.77 (10.29) FEXOFENADINE HYDROCHLORIDE F Tab 60 mg ...........................................................................................4.34 (11.53) F Tab 120 mg .........................................................................................4.74 (11.53) 14.22 (29.81) 100 200 ml 500 ml 20 Polaramine 40 Polaramine 100 ml Polaramine 20 Telfast 10 Telfast 30 Telfast

Zetop Cetirizine - AFT Histafen

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

159

RESPIRATORY SYSTEM AND ALLERGIES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

LORATADINE F Tab 10 mg ...........................................................................................2.09 F Oral liq 1 mg per ml ............................................................................3.10 PROMETHAZINE HYDROCHLORIDE F Tab 10 mg ...........................................................................................2.72 F Tab 25 mg ...........................................................................................4.44 F‡ Oral liq 5 mg per 5 ml .........................................................................3.10 F Inj 25 mg per ml, 2 ml – Up to 5 inj available on a PSO ...................11.00 TRIMEPRAZINE TARTRATE ‡ Oral liq 30 mg per 5 ml .......................................................................2.79 (8.06)

100 100 ml 50 50 100 ml 5 100 ml OP

Loraclear Hayfever

Relief

Lorapaed Allersoothe Allersoothe Promethazine

Winthrop Elixir

Mayne

Vallergan Forte

Inhaled Corticosteroids

BECLOMETHASONE DIPROPIONATE Aerosol inhaler, 100 µg per dose CFC-free ......................................12.50 Aerosol inhaler, 250 µg per dose CFC-free ......................................22.67 Aerosol inhaler, 50 µg per dose CFC-free ..........................................8.54 BUDESONIDE Powder for inhalation, 100 µg per dose ............................................17.00 Powder for inhalation, 200 µg per dose ............................................15.20 19.00 Powder for inhalation, 400 µg per dose ............................................25.60 32.00 FLUTICASONE Aerosol inhaler, 50 µg per dose CFC-free ..........................................7.50 Powder for inhalation, 50 µg per dose ................................................5.10 (8.67) Powder for inhalation, 100 µg per dose ..............................................7.50 (13.87) Aerosol inhaler, 125 µg per dose CFC-free ......................................13.60 Aerosol inhaler, 250 µg per dose CFC-free ......................................27.20 Powder for inhalation, 250 µg per dose ............................................13.60 (24.51) 200 dose OP 200 dose OP 200 dose OP 200 dose OP 200 dose OP

Beclazone 100 Beclazone 250 Beclazone 50 Pulmicort

Turbuhaler

Budenocort Pulmicort

Turbuhaler

200 dose OP

Budenocort Pulmicort

Turbuhaler

120 dose OP 60 dose OP 60 dose OP

Flixotide

Flixotide Accuhaler Flixotide Accuhaler

120 dose OP 120 dose OP 60 dose OP

Flixotide Flixotide

Flixotide Accuhaler

Inhaled Long-acting Beta-adrenoceptor Agonists

Prescribing Guideline for Inhaled Long-Acting Beta-Adrenoceptor Agonists The addition of inhaled long-acting beta-adrenoceptor agonists (LABAs) to inhaled corticosteroids is recommended: G For younger children (aged under 12 years) where asthma is poorly controlled despite using inhaled corticosteroids for at least three months at total daily doses of 200 µg beclomethasone or budesonide (or 100 µg ﬂuticasone). G For adults and older children (aged 12 years and over) where asthma is poorly controlled despite using inhaled corticosteroids for at least three months at total daily doses of 400 µg beclomethasone or budesonide (or 200 µg ﬂuticasone). Note: Further information on the place of inhaled corticosteroids and inhaled LABAs in the management of asthma can be found in the New Zealand guidelines for asthma in adults (www.nzgg.org.nz) and in the New Zealand guidelines for asthma in children aged 1-15 (www.paediatrics.org.nz).

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

160

RESPIRATORY SYSTEM AND ALLERGIES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

EFORMOTEROL FUMARATE – See prescribing guideline on the preceding page Additional subsidy by endorsement for Oxis Turbuhaler is available for patients where the initial dispensing was before 1 July 2011. Pharmacists may annotate prescriptions for patients who were being prescribed Oxis Turbuhaler prior to 1 July 2011 in which case the prescription is deemed to be endorsed. The pharmacist must be able to show a clear documented dispensing history for the patient. The prescription must been endorsed accordingly. Powder for inhalation, 6 µg per dose, breath activated – Higher subsidy of $16.90 per 60 dose with Endorsement .......... 14.60 60 dose OP (16.90) Oxis Turbuhaler Powder for inhalation, 12 µg per dose, and monodose device .........35.80 60 dose Foradil SALMETEROL – See prescribing guideline on the preceding page Aerosol inhaler CFC-free, 25 µg per dose ........................................26.46 Powder for inhalation, 50 µg per dose, breath activated ...................26.46 120 dose OP 60 dose OP

Serevent Serevent Accuhaler

Inhaled Corticosteroids with Long-Acting Beta-Adrenoceptor Agonists

¾SA0958 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 2 years for applications meeting the following criteria: Either: 1 All of the following: 1.1 Patient is a child under the age of 12; and 1.2 Both: Has, for 3 months of more, been treated with: 1.2.1 An inhaled long-acting beta adrenoceptor agonist; and 1.2.2 Inhaled corticosteroids at a dose of at least 400 µg per day beclomethasone or budesonide, or 200 µg per day ﬂuticasone; and 1.3 The prescriber considers that the patient would receive additional clinical beneﬁt from switching to a combination product; or 2 All of the following: 2.1 Patient is over the age of 12; and 2.2 Both: Has, for 3 months or more, been treated with: 2.2.1 An inhaled long-acting beta adrenoceptor agonist; and 2.2.2 Inhaled corticosteroids at a dose of at least 800 µg per day beclomethasone or budesonide, or 500 µg per day ﬂuticasone; and 2.3 The prescriber considers that the patient would receive additional clinical beneﬁt from switching to a combination product. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment.

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

161

RESPIRATORY SYSTEM AND ALLERGIES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

BUDESONIDE WITH EFORMOTEROL – Special Authority see SA0958 on the preceding page – Retail pharmacy Additional subsidy by endorsement for budesonide with eformoterol powder for inhalation (Symbicort Turbuhaler) is available for patients where the initial dispensing was before 1 July 2011. Pharmacists may annotate prescriptions for patients who were being prescribed budesonide with eformoterol powder for inhalation (Symbicort Turbuhaler) prior to 1 July 2011 in which case the prescription is deemed to be endorsed. The pharmacist must be able to show a clear documented dispensing history for the patient. The prescription must been endorsed accordingly. Aerosol inhaler 100 µg with eformoterol fumarate 6 µg ....................33.96 120 dose OP Vannair Powder for inhalation 100 µg with eformoterol fumarate 6 µg – Higher subsidy of $55.00 per 120 dose with Endorsement .........41.25 120 dose OP (55.00) Symbicort Turbuhaler 100/6 Aerosol inhaler 200 µg with eformoterol fumarate 6 µg ....................40.06 120 dose OP Vannair Powder for inhalation 200 µg with eformoterol fumarate 6 µg – Higher subsidy of $60.00 per 120 dose with Endorsement .........45.00 120 dose OP (60.00) Symbicort Turbuhaler 200/6 Powder for inhalation 400 µg with eformoterol fumarate 12 µg .........45.00 60 dose OP (60.00) Symbicort Turbuhaler 400/12 a) Higher subsidy of $60.00 per 60 dose with Endorsement b) No more than 2 dose per day FLUTICASONE WITH SALMETEROL – Special Authority see SA0958 on the preceding page – Retail pharmacy Aerosol inhaler 50 µg with salmeterol 25 µg .....................................37.48 120 dose OP Seretide Aerosol inhaler 125 µg with salmeterol 25 µg ...................................49.69 120 dose OP Seretide Powder for inhalation 100 µg with salmeterol 50 µg – No more than 2 dose per day....................................................................37.48 60 dose OP Seretide Accuhaler Powder for inhalation 250 µg with salmeterol 50 µg – No more than 2 dose per day....................................................................49.69 60 dose OP Seretide Accuhaler

Beta-Adrenoceptor Agonists

SALBUTAMOL ‡ Oral liq 2 mg per 5 ml .........................................................................1.99 Infusion 1 mg per ml, 5 ml ..............................................................118.38 (130.21) Inj 500 µg per ml, 1 ml – Up to 5 inj available on a PSO ..................12.90 150 ml 10 5

Salapin

Ventolin

Inhaled Beta-Adrenoceptor Agonists

SALBUTAMOL Aerosol inhaler, 100 µg per dose CFC free – Up to 1000 dose available on a PSO....................................................................... 3.80 (6.00) Nebuliser soln, 1 mg per ml, 2.5 ml – Up to 30 neb available on a PSO...................................................................................... 3.52 Nebuliser soln, 2 mg per ml, 2.5 ml – Up to 30 neb available on a PSO...................................................................................... 3.70 TERBUTALINE SULPHATE Powder for inhalation, 250 µg per dose, breath activated .................22.00

200 dose OP

Respigen Salamol

Ventolin

20 20 200 dose OP

Asthalin Asthalin Bricanyl Turbuhaler

162

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

RESPIRATORY SYSTEM AND ALLERGIES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Inhaled Anticholinergic Agents Inhaled Anticholinergic agents

IPRATROPIUM BROMIDE Aerosol inhaler, 20 µg per dose CFC-free ........................................16.20 Nebuliser soln, 250 µg per ml, 1 ml – Up to 40 neb available on a PSO......................................................................................3.79 Nebuliser soln, 250 µg per ml, 2 ml – Up to 40 neb available on a PSO......................................................................................4.06 200 dose OP 20 20

Atrovent Univent Univent Spiriva

TIOTROPIUM BROMIDE – Special Authority see SA0872 below – Retail pharmacy Powder for inhalation, 18 µg per dose ..............................................70.00 30 dose

¾SA0872 Special Authority for Subsidy Initial application only from a general practitioner or relevant specialist. Approvals valid for 2 years for applications meeting the following criteria: All of the following: 1 To be used for the long-term maintenance treatment of bronchospasm and dyspnoea associated with COPD; and 2 In addition to standard treatment, the patient has trialled a dose of at least 40 µg ipratropium q.i.d for one month; and 3 Either: The patient’s breathlessness according to the Medical Research Council (UK) dyspnoea scale is: 3.1 Grade 4 (stops for breath after walking about 100 meters or after a few minutes on the level); or 3.2 Grade 5 (too breathless to leave the house, or breathless when dressing or undressing); and 4 Actual FEV1 (litres) < 0.6 × predicted (litres); and 5 Either: 5.1 Patient is not a smoker (for reporting purposes only); or 5.2 Patient is a smoker and has been offered smoking cessation counselling; and 6 The patient has been offered annual inﬂuenza immunisation. Renewal only from a general practitioner or relevant specialist. Approvals valid for 2 years for applications meeting the following criteria: All of the following: 1 Patient is compliant with the medication; and 2 Patient has experienced improved COPD symptom control (prescriber determined); and 3 Applicant must state recent measurement of FEV1 (% of predicted).

Inhaled Beta-Adrenoceptor Agonists with Anticholinergic Agents

SALBUTAMOL WITH IPRATROPIUM BROMIDE Aerosol inhaler, 100 µg with ipratropium bromide, 20 µg per dose CFC-free ........................................................................... 12.19 Nebuliser soln, 2.5 mg with ipratropium bromide 0.5 mg per vial, 2.5 ml – Up to 20 neb available on a PSO ...........................4.29

200 dose OP 20

Duolin HFA Duolin

Mast Cell Stabilisers Mast cell stabilisers

NEDOCROMIL Aerosol inhaler, 2 mg per dose CFC-free .........................................28.07 SODIUM CROMOGLYCATE Powder for inhalation, 20 mg per dose .............................................17.94 Aerosol inhaler, 5 mg per dose CFC-free .........................................28.07 112 dose OP 50 dose 112 dose OP

Tilade Intal Spincaps Vicrom

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

163

RESPIRATORY SYSTEM AND ALLERGIES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Methylxanthines

AMINOPHYLLINE F Inj 25 mg per ml, 10 ml – Up to 5 inj available on a PSO .................53.75 THEOPHYLLINE F Tab long-acting 250 mg ....................................................................21.51 F‡ Oral liq 80 mg per 15 ml ...................................................................15.50 5 100 500 ml

DBL Aminophylline Nuelin-SR Nuelin

Mucolytics

DORNASE ALFA – Special Authority see SA0611 below – Retail pharmacy Nebuliser soln, 2.5 mg per 2.5 ml ampoule ....................................294.30 6

Pulmozyme

¾SA0611 Special Authority for Subsidy Special Authority approved by the Cystic Fibrosis Advisory Panel Notes: Application details may be obtained from PHARMAC’s website http://www.pharmac.govt.nz or: The Co-ordinator, Cystic Fibrosis Advisory Panel Phone: (04) 460 4990 PHARMAC, PO Box 10 254 Facsimile: (04) 916 7571 Wellington Email: CFPanel@pharmac.govt.nz Prescriptions for patients approved for treatment must be written by respiratory physicians or paediatricians who have experience and expertise in treating cystic ﬁbrosis. SODIUM CHLORIDE Not funded for use as a nasal drop. Only funded for nebuliser use when in conjunction with an antibiotic intended for nebuliser use. Soln 7% ............................................................................................23.50 90 ml OP Biomed

Nasal Preparations Allergy Prophylactics

BECLOMETHASONE DIPROPIONATE Metered aqueous nasal spray, 50 µg per dose ...................................2.35 (4.00) Metered aqueous nasal spray, 100 µg per dose .................................2.46 (4.81) BUDESONIDE Metered aqueous nasal spray, 50 µg per dose ...................................2.35 (4.00) Metered aqueous nasal spray, 100 µg per dose .................................2.61 (4.81) FLUTICASONE PROPIONATE Metered aqueous nasal spray, 50 µg per dose .................................13.34 IPRATROPIUM BROMIDE Aqueous nasal spray, 0.03% ..............................................................4.03 SODIUM CROMOGLYCATE Nasal spray, 4% ................................................................................15.85 200 dose OP Alanase 200 dose OP Alanase 200 dose OP Butacort Aqueous 200 dose OP Butacort Aqueous 120 dose OP

Flixonase Hayfever

& Allergy

15 ml OP 22 ml OP

Univent Rex

164

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

RESPIRATORY SYSTEM AND ALLERGIES

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Respiratory Devices

MASK FOR SPACER DEVICE a) Up to 20 dev available on a PSO b) Only on a PSO c) Only for children aged six years and under Size 2 ..................................................................................................2.99 PEAK FLOW METER a) Up to 10 dev available on a PSO b) Only on a PSO Low range .........................................................................................11.44 Normal range ....................................................................................11.44 SPACER DEVICE a) Up to 20 dev available on a PSO b) Only on a PSO 230 ml (single patient) .......................................................................4.72

EZ-ﬁt Paediatric

Mask

1 1

Breath-Alert Breath-Alert

Space Chamber Space Chamber

Plus

800 ml .................................................................................................8.50 (Space Chamber 230 ml (single patient) to be delisted 1 February 2012)

Volumatic

SPACER DEVICE AUTOCLAVABLE a) Up to 5 dev available on a PSO b) Only on a PSO 230 ml (autoclavable) – Subsidy by endorsement.............................11.60 1 Space Chamber Available where the prescriber requires a spacer device that is capable of sterilisation in an autoclave and the PSO is endorsed accordingly.

Respiratory Stimulants

CAFFEINE CITRATE Oral liq 20 mg per ml (10 mg base per ml) .......................................14.85 25 ml OP

Biomed

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

165

SENSORY ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Ear Preparations

ACETIC ACID WITH 1, 2- PROPANEDIOL DIACETATE AND BENZETHONIUM For Vosol ear drops with hydrocortisone powder refer, page 175 Ear drops 2% with 1, 2-Propanediol diacetate 3% and benzethonium chloride 0.02% ..................................................... 6.97 CHLORAMPHENICOL Ear drops 0.5% ...................................................................................2.20 FLUMETASONE PIVALATE Ear drops 0.02% with clioquinol 1% ...................................................4.46

35 ml OP 5 ml OP 7.5 ml OP

Vosol Chloromycetin Locacorten-Viaform

ED’s

Locorten-Vioform

TRIAMCINOLONE ACETONIDE WITH GRAMICIDIN, NEOMYCIN AND NYSTATIN Ear drops 1 mg with nystatin 100,000 u, neomycin sulphate 2.5 mg and gramicidin 250 µg per g ............................................ 5.16 7.5 ml OP

Kenacomb

Ear/Eye Preparations

DEXAMETHASONE WITH FRAMYCETIN AND GRAMICIDIN Ear/Eye drops 500 µg with framycetin sulphate 5 mg and gramicidin 50 µg per ml ............................................................... 4.50 (9.27) FRAMYCETIN SULPHATE Ear/Eye drops 0.5% ............................................................................4.13 (8.65)

8 ml OP Sofradex 8 ml OP Soframycin

Eye Preparations

Eye preparations are only funded for use in the eye. The exception is pilocarpine eye drops 1%, 2% and 4% which are subsidised for oral use pursuant to the Standard Formulae.

Anti-Infective Preparations

ACICLOVIR F Eye oint 3% ......................................................................................37.53 CHLORAMPHENICOL Eye oint 1% ........................................................................................2.37 Eye drops 0.5% ..................................................................................1.28 4.5 g OP 4 g OP 10 ml OP

Zovirax Chlorsig Chlorafast

CIPROFLOXACIN Eye Drops 0.3% ................................................................................12.43 5 ml OP Ciloxan For treatment of bacterial keratitis or severe bacterial conjunctivitis resistant to chloramphenicol. FUSIDIC ACID Eye drops 1% .....................................................................................4.50 5 g OP Fucithalmic GENTAMICIN SULPHATE Eye drops 0.3% ................................................................................11.40 PROPAMIDINE ISETHIONATE F Eye drops 0.1% ..................................................................................2.97 (7.99) 5 ml OP 10 ml OP Brolene

Genoptic

166

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

SENSORY ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

TOBRAMYCIN Eye oint 0.3% ...................................................................................10.45 Eye drops 0.3% ................................................................................11.48

3.5 g OP 5 ml OP

Tobrex Tobrex

Corticosteroids and Other Anti-Inﬂammatory Preparations

DEXAMETHASONE F Eye oint 0.1% .....................................................................................5.86 F Eye drops 0.1% ..................................................................................4.50 DEXAMETHASONE WITH NEOMYCIN AND POLYMYXIN B SULPHATE F Eye oint 0.1% with neomycin sulphate 0.35% and polymyxin B sulphate 6,000 u per g .............................................................5.39 F Eye drops 0.1% with neomycin sulphate 0.35% and polymyxin B sulphate 6,000 u per ml ......................................................4.50 DICLOFENAC SODIUM F Eye drops 1 mg per ml .....................................................................13.80 FLUOROMETHOLONE F Eye drops 0.1% ..................................................................................4.05 LEVOCABASTINE Eye drops 0.5 mg per ml ....................................................................8.71 (10.34) LODOXAMIDE TROMETAMOL Eye drops 0.1% ..................................................................................8.71 PREDNISOLONE ACETATE F Eye drops 0.12% ................................................................................4.50 F Eye drops 1% .....................................................................................4.50 SODIUM CROMOGLYCATE Eye drops 2% .....................................................................................1.18 3.5 g OP 5 ml OP

Maxidex Maxidex

3.5 g OP 5 ml OP 5 ml OP 5 ml OP 4 ml OP

Maxitrol Maxitrol Voltaren Ophtha FML

Livostin 10 ml OP 5 ml OP 5 ml OP 5 ml OP

Lomide Pred Mild Pred Forte Rexacrom

Glaucoma Preparations - Beta Blockers

BETAXOLOL HYDROCHLORIDE F Eye drops 0.25% ..............................................................................11.80 F Eye drops 0.5% ..................................................................................7.50 LEVOBUNOLOL F Eye drops 0.25% ................................................................................7.00 F Eye drops 0.5% ..................................................................................7.00 TIMOLOL MALEATE F Eye drops 0.25% ................................................................................2.08 2.37 F Eye drops 0.25%, gel forming ............................................................3.30 F Eye drops 0.5% ..................................................................................2.08 2.29 F Eye drops 0.5%, gel forming ..............................................................3.78 5 ml OP 5 ml OP 5 ml OP 5 ml OP 5 ml OP 2.5 ml OP 5 ml OP 2.5 ml OP

Betoptic S Betoptic Betagan Betagan Arrow-Timolol Apo-Timop Timoptol XE Arrow-Timolol Apo-Timop Timoptol XE

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

167

SENSORY ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Glaucoma Preparations - Carbonic Anhydrase Inhibitors

Prescribing Guidelines Trusopt, Cosopt and Azopt are subsidised for use as either monotherapy or as an adjunctive agent for the treatment of glaucoma. Trusopt, Cosopt and Azopt should not be prescribed for a person in whom less expensive ﬁrst line agents for the treatment of glaucoma are not contraindicated unless: 1) that person has previously trialled all other such subsidised agents (except brimonidine tartrate); and 2) those trials have indicated that that person does not respond adequately to treatment with those other agents. ACETAZOLAMIDE F Tab 250 mg – For acetazolamide oral liquid formulation refer, page 172 ....................................................................................17.03 100 Diamox BRINZOLAMIDE L Eye Drops 1% .....................................................................................9.77 DORZOLAMIDE HYDROCHLORIDE F Eye drops 2% .....................................................................................9.77 (13.95) DORZOLAMIDE HYDROCHLORIDE WITH TIMOLOL MALEATE F Eye drops 2% with timolol maleate 0.5% .........................................15.50 5 ml OP 5 ml OP Trusopt 5 ml OP

Azopt

Cosopt

Glaucoma Preparations - Prostaglandin Analogues

Prescribing Guideline Bimatoprost, lantanoprost and travoprost are subsidised for use in the treatment of glaucoma as either monotherapy or as an adjunctive agent for patients in whom prostaglandin analogue monotherapy has been ineffective in controlling intraocular pressure. Bimatoprost, lantanoprost and travoprost should not be prescribed for a person in whom less expensive ﬁrst line agents for the treatment of glaucoma are not contraindicated unless: 1) That person has previously trialled all other such subsidised agents (beta-blockers, pilocarpine, carbonic anhydrase inhibitors); and 2) Those trials have indicated that that person does not respond adequately to treatment with those other agents. BIMATOPROST – Retail pharmacy-Specialist See prescribing guideline below L Eye drops 0.03% ..............................................................................19.50 3 ml OP Lumigan LATANOPROST – Retail pharmacy-Specialist See prescribing guideline below L Eye drops 50 µg per ml, 2.5 ml ...........................................................9.75 TRAVOPROST – Retail pharmacy-Specialist See prescribing guideline below L Eye drops 0.004% ............................................................................19.50

2.5 ml OP

Hysite

2.5 ml OP

Travatan

Glaucoma Preparations - Other

BRIMONIDINE TARTRATE – See prescribing guideline below F Eye Drops 0.2% ..................................................................................7.93 5 ml OP AFT Prescribing Guidelines Brimonidine tartrate is subsidised for use as either monotherapy or as an adjunctive agent for the treatment of glaucoma. Brimonidine tartrate should not be prescribed for a person in whom less expensive ﬁrst line agents for the treatment of glaucoma are not contraindicated unless: G that person has previously trialled all other such subsidised agents (except dorzolamide hydrochloride); and G those trials have indicated that that person does not respond adequately to or does not tolerate treatment with those other agents.

168

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

SENSORY ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

BRIMONIDINE TARTRATE WITH TIMOLOL MALEATE – See prescribing guideline below L Eye drops 0.2% with timolol maleate 0.5% ......................................18.50 5 ml OP

Combigan

Prescribing Guidelines Combigan is subsidised for use as either monotherapy or as an adjunctive agent for the treatment of glaucoma. Combigan should only be prescribed when: 1) less expensive ﬁrst line agents for the treatment of glaucoma are contraindicated; or 2) the response to such subsidised agents is inadequate; or 3) the patient cannot tolerate such subsidised agents. PILOCARPINE F Eye drops 1% .....................................................................................4.26 15 ml OP Isopto Carpine F Eye drops 2% .....................................................................................5.35 15 ml OP Isopto Carpine F Eye drops 4% .....................................................................................7.99 15 ml OP Isopto Carpine F Eye drops 2% single dose – Special Authority see SA0895 below – Retail pharmacy ........................................................... 31.95 20 dose (32.72) Minims ¾SA0895 Special Authority for Subsidy Initial application from any relevant practitioner. Approvals valid for 2 years for applications meeting the following criteria: Either: 1 Patient has to use an unpreserved solution due to an allergy to the preservative; or 2 Patient wears soft contact lenses. Note: Minims for a general practice are considered to be “tools of trade” and are not approved as special authority items. Renewal from any relevant practitioner. Approvals valid for 2 years where the treatment remains appropriate and the patient is beneﬁting from treatment.

Mydriatics and Cycloplegics

ATROPINE SULPHATE F Eye drops 1% ...................................................................................17.36 CYCLOPENTOLATE HYDROCHLORIDE F Eye drops 1% .....................................................................................8.76 HOMATROPINE HYDROBROMIDE F Eye drops 2% .....................................................................................7.18 TROPICAMIDE F Eye drops 0.5% ..................................................................................7.15 F Eye drops 1% .....................................................................................8.66 15 ml OP 15 ml OP 15 ml OP 15 ml OP 15 ml OP

Atropt Cyclogyl Isopto Homatropine Mydriacyl Mydriacyl

Preparations for Tear Deﬁciency

For acetylcysteine eye drops refer, page 175 HYPROMELLOSE F Eye drops 0.3% ..................................................................................2.62 F Eye drops 0.5% ..................................................................................2.00 POLYVINYL ALCOHOL F Eye drops 1.4% ..................................................................................2.68 F Eye drops 3% .....................................................................................3.75 TYLOXAPOL F Eye drops 0.25% ................................................................................8.63

15 ml OP 15 ml OP 15 ml OP 15 ml OP 15 ml OP

Poly-Tears Methopt Vistil Vistil Forte Enuclene

‡ safety cap FThree months or six months, as applicable, dispensed all-at-once

LThree months supply may be dispensed at one time if endorsed “certiﬁed exemption” by the prescriber.

169

SENSORY ORGANS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Other Eye Preparations

NAPHAZOLINE HYDROCHLORIDE F Eye drops 0.1% ..................................................................................4.15 PARAFFIN LIQUID WITH SOFT WHITE PARAFFIN F Eye oint with soft white parafﬁn ..........................................................3.63 PARAFFIN LIQUID WITH WOOL FAT LIQUID F Eye oint 3% with wool fat liq 3% .........................................................3.63 PHENYLEPHRINE HYDROCHLORIDE F Eye drops 0.12% ................................................................................4.47 15 ml OP 3.5 g OP 3.5 g OP 15 ml OP

Naphcon Forte Lacri-Lube Poly-Visc Prefrin

170

fully subsidised [HP4] refer page 9

S29 Unapproved medicine supplied under Section 29 Sole Subsidised Supply

SECTION C: EXTEMPORANEOUSLY COMPOUNDED PRODUCTS & GALENICALS

INTRODUCTION

The following extemporaneously compounded products are eligible for subsidy:

G G G G

The “Standard Formulae”. Oral liquid mixtures for patients unable to swallow subsidised solid dose oral formulations. The preparation of syringe drivers when prescribed by a general practitioner. Dermatological preparations a) One or more subsidised dermatological galenical(s) in a subsidised dermatological base. b) Dilution of proprietary Topical Corticosteroid-Plain preparations with a dermatological base (Retail pharmacy-specialist). c) Menthol crystals only in the following bases: Aqueous cream Urea cream 10% Wool fat with mineral oil lotion Hydrocortisone 1% with wool fat and mineral oil lotion Glycerol, parafﬁn and cetyl alcohol lotion.

Glossary

Dermatological base: The products listed in the Barrier creams and Emollients section and the Topical Corticosteroids-Plain section of the Pharmaceutical Schedule are classiﬁed as dermatological bases for the purposes of extemporaneous compounding and are the bases to which the dermatological galenicals can be added. Also the dermatological bases in the Barrier Creams and Emollients section of the Pharmaceutical Schedule can be used for diluting proprietary Topical Corticosteroid-Plain preparations. The following products are dermatological bases:

G G G G G G G G G G G

Aqueous cream Cetomacrogol cream BP Collodion ﬂexible Emulsifying ointment BP Hydrocortisone with wool fat and mineral oil lotion Oil in water emulsion Urea cream 10% White soft parafﬁn Wool fat with mineral oil lotion Zinc and castor oil ointment BP Proprietary Topical Corticosteroid-Plain preparations

Dermatological galenical: Dermatological galenicals will only be subsidised when added to a dermatological base. More than one dermatological galenical can be added to a dermatological base. The following are dermatological galenicals:

G G G G G

Coal tar solution BP - up to 10% Hydrocortisone powder - up to 5% Menthol crystals Salicylic acid powder Sulphur precipitated powder

Standard formulae: Standard formulae are a list of fomulae for ECPs that are subsidised. Their ingredients are listed under the appropriate therapeutic heading in Section B of the Pharmaceutical Schedule and also in Section C.

171

Explanatory notes

Oral liquid mixtures Oral liquid mixtures are subsidised for patients unable to swallow subsidised solid oral dose forms where no suitable alternative proprietary formulation is subsidised. Suitable alternatives include dispersible and sublingual formulations, oral liquid formulations or rectal formulations. Before extemporaneously compounding an oral liquid mixture, other alternatives such as dispersing the solid dose form (if appropriate) or crushing the solid dose form in jam, honey or soft foods such as yoghurt should be explored. The Emixt website www.pharminfotech.co.nz has evidence-based formulations which are intended to standardise compounded oral liquids within New Zealand. Pharmaceuticals with standardised formula for compounding in Ora products Acetazolamide 25 mg/ml Allopurinol 20 mg/ml Amlodipine 1 mg/ml Azathioprine 50 mg/ml Baclofen 10 mg/ml Carvedilol 1 mg/ml Clopidogrel 5 mg/ml Diltiazem hydrochloride 12 mg/ml Dipyridamole 10 mg/ml Domperidone 1 mg/ml Enalapril 1 mg/ml *Note this is a DCS formulation PHARMAC endorses the recommendations of the Emixt website and encourages New Zealand pharmacists to use these formulations when compounding is appropriate. The Emixt website also provides stability and expiry data for compounded products. For the majority of products compounded with Ora-Blend, Ora-Blend SF, Ora-Plus, Ora-Sweet or Ora-Sweet SF a four week expiry is appropriate. Please note that no oral liquid mixture will be eligible for Subsidy unless all the requirements of Section B and C of the Schedule applicable to that pharmaceutical are met. Some community pharmacies may not have appropriate equipment to compound all of the listed products, please use appropriate clinical judgement. Subsidy for extemporaneously compounded oral liquid mixtures is based on: qs Solid dose form qs Preservative Suspending agent qs Water to 100% or qs Solid dose form Ora-Blend, Ora-Blend SF, Ora-Plus, Ora-Sweet and/or Ora-Sweet SF to 100% Prescribers may prescribe or pharmacists may add extra non-subsidised ingredients such as ﬂavouring and colouring agents, but these extra ingredients will not be reimbursed. The subsidised ingredients in the formula will be reimbursed and a compounding fee paid. The majority of extemporaneously compounded oral liquid mixtures should contain a preservative and suspending agent. G Ora-Blend, Ora-Blend SF, Ora-Plus, Ora-Sweet and Ora-Sweet SF when used correctly are an appropriate preservative and suspending agent. G Methylcellulose 3% is considered a suitable suspending agent and compound hydroxybenzoate solution or methyl hydroxybenzoate 10% solution are considered to be suitable preservatives. Usually 1 ml of these preservative solutions is added to 100 ml of oral liquid mixture. Some solid oral dose forms are not appropriate for compounding into oral liquid mixtures and should therefore not be used/considered for extemporaneously compounded oral liquid mixtures. This includes long-acting solid dose formulations, enteric coated tablets or capsules, sugar coated tablets, hard gelatin capsules and chemotherapeutic agents. Flecainide 20 mg/ml Gabapentin 100 mg/ml Gabapentin (Neurontin) 100 mg/ml Hydrocortisone 1 mg/ml Labetolol 10 mg/ml Levetiracetam 100 mg/ml Levodopa with carbidopa (5 mg levodopa + 1.25 mg carbidopa)/ml Metoprolol tartrate 10 mg/ml Nitrofurantoin 10 mg/ml Pyrazinamide 100 mg/ml Rifabutin 20 mg/ml Sildenaﬁl 2 mg/ml Sotalol 15 mg/ml Sulphasalazine 100 mg/ml Tacrolimus 1 mg/ml Terbinaﬁne 25 mg/ml Ursodeoxycholic acid 50 mg/ml Valganciclovir 60 mg/ml* Verapamil hydrochloride 50 mg/ml

172

EXTEMPORANEOUSLY COMPOUNDED PRODUCTS & GALENICALS

The following practices will not be subsidised: G Where a Standard Formula exists in the Pharmaceutical Schedule for a solid dose form, compounding the solid dose form in Ora-Blend, Ora-Blend SF, Ora-Plus, Ora-Sweet and/or Ora-Sweet SF. G Mixing one or more proprietary oral liquids (eg an antihistamine with pholcodine linctus). G Extemporaneously compounding an oral liquid with more than one solid dose chemical. G Mixing more than one extemporaneously compounded oral liquid mixture. G Mixing one or more extemporaneously compounded oral liquid mixtures with one or more proprietary oral liquids. G The addition of a chemical/powder/agent/solution to a proprietary oral liquid or extemporaneously compounded oral mixture. Standard formulae A list of standard formulae is contained in this section. All ingredients associated with a standard formula will be subsidised and an appropriate compounding fee paid. Prescribers may prescribe or pharmacists may add extra non-subsidised ingredients, but these extra ingredients will not be reimbursed. The subsidised ingredients in the formula will be reimbursed and a compounding fee paid. Dermatological Preparations Proprietary topical corticosteroid preparations may be diluted with a dermatological base (see page 171) from the Barrier Creams and Emollients section of the Pharmaceutical Schedule (Retail pharmacy-Specialist). Dilution of proprietary topical corticosteroid preparations should only be prescribed for withdrawing patients off higher strength proprietary topical corticosteroid products where there is no suitable proprietary product of a lower strength available or an extemporaneously compounded product with up to 5% hydrocortisone is not appropriate. (In general proprietary topical corticosteroid preparations should not be diluted because dilution effects can be unpredictable and may not be linear, and usually there is no stability data available for diluted products). One or more dermatological galenicals may be added to a dermatological base (including proprietary topical corticosteroid preparations). Prescribers may prescribe or pharmacists may add extra non-subsidised ingredients, but these extra ingredients will not be reimbursed. The subsidised ingredients in the formula will be reimbursed and a compounding fee paid. The addition of dermatological galenicals to diluted proprietary Topical Corticosteroids-Plain will not be subsidised. The ﬂow diagram on the next page may assist you in deciding whether or not a dermatological ECP is subsidised.

173

EXTEMPORANEOUSLY COMPOUNDED PRODUCTS & GALENICALS

Dermatological ECPs

Is it subsidised?

Does the formula contain a subsidised dermatological base? Yes Is there only one dermatological base (e.g. aqueous cream)? Yes Is the galenical(s) a subsidised dermatological galenical? Yes Is the second base a proprietary topical corticosteroid-plain? No Is prescription written by a specialist or on the recommendation of a specialist? Entire product is NSS

Yes

Entire product is NSS

This part of the product is subsidised

Yes

Has a non-subsidised ingredient been added: e.g. glycerol?

Has a dermatological galenical or other non-subsidised ingredient been added? Yes

Yes

The non-subsidised ingredient is not subsidised but the rest is

The dermatological galenicals & non-subsidised ingredients are NSS

174

EXTEMPORANEOUSLY COMPOUNDED PRODUCTS & GALENICALS

Standard Formulae

ACETYLCYSTEINE EYE DROPS Acetylcysteine inj 200 mg per ml, 10 ml qs Suitable eye drop base qs ASPIRIN AND CHLOROFORM APPLICATION Aspirin Soluble tabs 300 mg 12 tabs Chloroform to 100 ml CODEINE LINCTUS PAEDIATRIC (3 mg per 5 ml) Codeine phosphate 60 mg Glycerol 40 ml Preservative qs Water to 100 ml CODEINE LINCTUS DIABETIC (15 mg per 5 ml) Codeine phosphate 300 mg Glycerol 40 ml Preservative qs Water to 100 ml FOLINIC MOUTHWASH Calcium folinate 15 mg tab 1 tab Preservative qs Water to 500 ml (Preservative should be used if quantity supplied is for more than 5 days. Maximum 500 ml per prescription.) MAGNESIUM HYDROXIDE MIXTURE Magnesium hydroxide paste Methyl hydroxybenzoate Water METHADONE MIXTURE Methadone powder Glycerol Water

METHYL HYDROXYBENZOATE 10% SOLUTION Methyl hydroxybenzoate 10 g Propylene glycol to 100 ml (Use 1 ml of the 10% solution per 100 ml of oral liquid mixture) OMEPRAZOLE SUSPENSION Omeprazole capules or powder Sodium bicarbonate powder BP Water PHENOBARBITONE ORAL LIQUID Phenobarbitone Sodium Glycerol BP Water qs 8.4 g to 100 ml 1g 70 ml to 100 ml

PHENOBARBITONE SODIUM PAEDIATRIC ORAL LIQUID (10 mg per ml) Phenobarbitone Sodium 400 mg Glycerol BP 4 ml Water to 40 ml PILOCARPINE ORAL LIQUID Pilocarpine 4% eye drops qs Preservative qs Water to 500 ml (Preservative should be used if quantity supplied is for more than 5 days.) SALIVA SUBSTITUTE FORMULA Methylcellulose 5g Preservative qs Water to 500 ml (Preservative should be used if quantity supplied is for more than 5 days. Maximum 500 ml per prescription.) VOSOL EAR DROPS WITH HYDROCORTISONE POWDER 1% Hydrocortisone powder 1% Vosol Ear Drops to 35 ml

275 g 1.5 g 770 ml qs qs to 100 ml

175

EXTEMPORANEOUSLY COMPOUNDED PREPARATIONS AND GALENICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Extemporaneously Compounded Preparations and Galenicals

ACETYLCYSTEINE – Retail pharmacy-Specialist Inj 200 mg per ml, 10 ml .................................................................137.06 (219.75) (255.35) Inj 200 mg per ml, 30 ml .................................................................219.00 BENZOIN Tincture compound BP .......................................................................2.44 (5.10) 24.42 (38.00) CHLOROFORM – Only in combination Only in aspirin and chloroform application. Chloroform BP ..................................................................................25.50 10 Martindale Acetylcysteine Hospira Acetadote

4 50 ml

PSM 500 ml PSM

500 ml

PSM

CODEINE PHOSPHATE Powder – Only in combination .........................................................12.62 5g (25.46) Douglas 63.09 25 g (90.09) Douglas a) Only in extemporaneously compounded codeine linctus diabetic or codeine linctus paediatric. b) ‡ Safety cap for extemporaneously compounded oral liquid preparations. COLLODION FLEXIBLE Collodion ﬂexible ..............................................................................19.30 100 ml PSM COMPOUND HYDROXYBENZOATE – Only in combination Only in extemporaneously compounded oral mixtures. Soln ..................................................................................................34.18 GLYCERIN WITH SODIUM SACCHARIN – Only in combination Only in combination with Ora-Plus. Suspension .......................................................................................36.80 GLYCERIN WITH SUCROSE – Only in combination Only in combination with Ora-Plus. Suspension .......................................................................................36.80 GLYCEROL F Liquid – Only in combination ...........................................................17.86 Only in extemporaneously compounded oral liquid preparations. MAGNESIUM HYDROXIDE Paste ................................................................................................22.61

100 ml

David Craig

473 ml

Ora-Sweet SF

473 ml 2,000 ml

Ora-Sweet healthE

500 g

PSM

176

fully subsidised

[HP3], [HP4] refer page 9

EXTEMPORANEOUSLY COMPOUNDED PREPARATIONS AND GALENICALS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

METHYL HYDROXYBENZOATE Powder ................................................................................................8.00 8.98 METHYLCELLULOSE Powder ..............................................................................................14.00 (17.72) Suspension – Only in combination ..................................................36.80

25 g

PSM Midwest ABM

MidWest

100 g 473 ml

Ora-Plus Ora-Blend SF Ora-Blend MidWest MidWest

METHYLCELLULOSE WITH GLYCERIN AND SODIUM SACCHARIN – Only in combination Suspension .......................................................................................36.80 473 ml METHYLCELLULOSE WITH GLYCERIN AND SUCROSE – Only in combination Suspension .......................................................................................36.80 473 ml

PHENOBARBITONE SODIUM Powder – Only in combination .........................................................52.50 10 g 325.00 100 g a) Only in children up to 12 years b) ‡ Safety cap for extemporaneously compounded oral liquid preparations. PROPYLENE GLYCOL Only in extemporaneously compounded methyl hydroxybenzoate 10% solution. Liq .....................................................................................................10.50 500 ml 11.25 12.00 SODIUM BICARBONATE Powder BP – Only in combination .....................................................8.95 9.80 (29.50) Only in extemporaneously compounded omeprazole suspension. SYRUP (PHARMACEUTICAL GRADE) – Only in combination Only in extemporaneously compounded oral liquid preparations. Liq .....................................................................................................21.75 WATER Tap – Only in combination .................................................................0.00 500 g

PSM Midwest ABM Midwest

David Craig

2,000 ml 1 ml

Midwest Tap water

fully subsidised

[HP3], [HP4] refer page 9

177

SECTION D: SPECIAL FOODS

EXPLANATORY NOTES

The list of special foods to which Subsidies apply is contained in this section. The list of available products, guidelines for use, subsidies and charges is reviewed as required. Applications for new listings and changes to subsidies and access criteria will be considered by the special foods sub-committee of PTAC which meets as and when required. In all cases, subsidies are available by Special Authority only. This means that, unless a patient has a valid Special Authority number for their special food requirements, they must pay the full cost of the products themselves. Eligibility for Special Authority Special Authorities will be approved for patients meeting conditions speciﬁed under the Conditions and Guidelines for each product. In some cases there are also limits to how products can be prescribed (for example quantity, use or duration). Only those brands, presentations and ﬂavours of special foods listed in this section are subsidised. Who can apply for Special Authority? Only from a dietitian, relevant specialist or a vocationally registered general practitioner. Reapplications: Only from a dietitian, relevant specialist or a vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or a vocationally registered general practitioner. Other general practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and the date contacted. All applications must be made on an ofﬁcial form available from the PHARMAC website www.pharmac.govt.nz. All applications must include speciﬁc details as requested on the form relating to the application. Applications must be forwarded to: Ministry of Health Sector Services Private Bag 3015 WHANGANUI 4540 Freefax 0800 100 131 Initial Applications: Subsidies and manufacturer’s surcharges The Subsidies for some special foods are based on the lowest priced product within each group. Where this is so, or where special foods are otherwise not fully subsidised, a manufacturer’s surcharge may be payable by the patient. The manufacturer’s surcharge is the difference between the price of the product and the subsidy attached to it and may be subject to mark-ups applied at a pharmacy level. As a result the manufacturer’s surcharge may vary. Fully subsidised alternatives are available in most cases (as indicated by a tick in the left hand column). Patients should only have to pay a co-payment on these products. Where are special foods available from? Distribution arrangements for special foods vary from region to region. Special foods are available from hospital pharmacies providing an outpatient dispensing service as well as retail pharmacies in the Northern, Midland and Central (including Nelson and Blenheim) regions. Deﬁnitions Failure to thrive Growth deﬁciency An inability to gain or maintain weight resulting in physiological impairment. Where the weight of the child is less than the ﬁfth or possibly third percentile for their age, with evidence of malnutrition

178

SPECIAL FOODS

Dietitian Prescribing Prescriptions from Dietitians will be only valid for subsidy where they are for special foods, as listed in this section, or where they are for the following products: ASCORBIC ACID Tab 100 mg CALCIUM CARBONATE Tab eff 1.75 g (1 g elemental) Tab 1.25 g (500 mg elemental) Tab 1.5 g (600 mg elemental) COMPOUND ELECTROLYTES Powder for soln for oral use 4.4 g Powder for soln for oral use 5 g DEXTROSE WITH ELECTROLYTES Soln with electrolytes FERROUS FUMARATE Tab 200 mg (65 mg elemental) FERROUS FUMARATE WITH FOLIC ACID Tab 310 mg (100 mg elemental) with folic acid 350 µg FERROUS SULPHATE Tab long-acting 325 mg (105 mg elemental) Oral liq 30 mg per 1 ml (6 mg elemental per 1 ml) FERROUS SULPHATE WITH FOLIC ACID Tab long-acting 325 mg (105 mg elemental) with folic acid 350 µg MULTIVITAMINS Powder POTASSIUM BICARBONATE Tab eff 315 mg with sodium acid phosphate 1.937 g and sodium bicarbonate 350 mg POTASSIUM CHLORIDE Tab eff 548 mg (14 m eq) with chloride 285 mg (8 m eq) Tab long-acting 600 mg PYRIDOXINE HYDROCHLORIDE Tab 25 mg Tab 50 mg SODIUM FLUORIDE Tab 1.1 mg (0.5 mg elemental) THIAMINE HYDROCHLORIDE Tab 50 mg VITAMIN A WITH VITAMINS D AND C Soln 1000 u with Vitamin D 400 u and ascorbic acid 30 mg per 10 drops VITAMIN B COMPLEX Tab, strong, BPC VITAMINS Tab (BPC cap strength) Cap (fat soluble vitamins A, D, E, K)

179

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Nutrient Modules Carbohydrate

¾SA1090 Special Authority for Subsidy Initial application — (Cystic ﬁbrosis or renal failure) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: Either: 1 cystic ﬁbrosis; or 2 chronic renal failure or continuous ambulatory peritoneal dialysis (CAPD) patient. Initial application — (Indications other than cystic ﬁbrosis or renal failure) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Any of the following: 1 cancer in children; or 2 cancers affecting alimentary tract where there are malabsorption problems in patients over the age of 20 years; or 3 failure to thrive; or 4 growth deﬁciency; or 5 bronchopulmonary dysplasia; or 6 premature and post premature infant; or 7 inborn errors of metabolism. Renewal — (Cystic ﬁbrosis or renal failure) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian,relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. Renewal — (Indications other than cystic ﬁbrosis or renal failure) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. CARBOHYDRATE SUPPLEMENT – Special Authority see SA1090 above – Hospital pharmacy [HP3] Powder ................................................................................................5.29 400 g OP Polycal 36.50 5,000 g Morrex Maltodextrin 182.50 25,000 g Morrex Maltodextrin 1.30 368 g OP (12.00) Moducal (Morrex Maltodextrin Powder to be delisted 1 March 2012)

Carbohydrate And Fat

¾SA1091 Special Authority for Subsidy Initial application — (Cystic ﬁbrosis) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: Both: 1 infant aged four years or under; and 2 cystic ﬁbrosis. continued. . .

180

fully subsidised

[HP3], [HP4] refer page 9

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . Initial application — (Indications other than cystic ﬁbrosis) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 infant aged four years or under; and 2 Any of the following: 2.1 cancer in children; or 2.2 failure to thrive; or 2.3 growth deﬁciency; or 2.4 bronchopulmonary dysplasia; or 2.5 premature and post premature infants. Renewal — (Cystic ﬁbrosis) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. Renewal — (Indications other than cystic ﬁbrosis) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. CARBOHYDRATE AND FAT SUPPLEMENT – Special Authority see SA1091 on the preceding page – Hospital pharmacy [HP3] Powder (neutral) ...............................................................................60.31 400 g OP Duocal Super Soluble Powder

Fat

¾SA1092 Special Authority for Subsidy Initial application — (Inborn errors of metabolism) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years where the patient has inborn errors of metabolism. Initial application — (Indications other than inborn errors of metabolism) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Any of the following: 1 failure to thrive where other high calorie products are inappropriate or inadequate; or 2 growth deﬁciency; or 3 bronchopulmonary dysplasia; or 4 fat malabsorption; or 5 lymphangiectasia; or 6 short bowel syndrome; or 7 infants with necrotising enterocolitis; or 8 biliary atresia. Renewal — (Inborn errors of metabolism) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and continued. . .

fully subsidised

[HP3], [HP4] refer page 9

181

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. Renewal — (Indications other than inborn errors of metabolism) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. FAT SUPPLEMENT – Special Authority see SA1092 on the preceding page – Hospital pharmacy [HP3] Emulsion (neutral) ............................................................................12.30 200 ml OP Calogen 30.75 500 ml OP Calogen Emulsion (strawberry) .......................................................................12.30 200 ml OP Calogen Oil .....................................................................................................28.73 250 ml OP Liquigen 30.00 500 ml OP MCT oil (Nutricia)

Protein

¾SA1093 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Either: 1 protein losing enteropathy; or 2 high protein needs (eg burns). Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. PROTEIN SUPPLEMENT – Special Authority see SA1093 above – Hospital pharmacy [HP3] Powder ................................................................................................7.90 225 g OP Protifar 8.95 227 g OP Resource Beneprotein Powder (vanilla) ................................................................................12.90 275 g OP Promod

Oral Supplements/Complete Diet (Nasogastric/Gastrostomy Tube Feed) Respiratory Products

¾SA1094 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year where the patient has CORD and hypercapnia. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted.

182

fully subsidised

[HP3], [HP4] refer page 9

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

CORD ORAL FEED 1.5KCAL/ML – Special Authority see SA1094 on the preceding page – Hospital pharmacy [HP3] Liquid ..................................................................................................1.66 237 ml OP Pulmocare

Diabetic Products

¾SA1095 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year where the patient is a type I or and II diabetic who is suffering weight loss and malnutrition that requires nutritional support. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. DIABETIC ENTERAL FEED 1KCAL/ML – Special Authority see SA1095 above – Hospital pharmacy [HP3] Liquid ..................................................................................................7.50 1,000 ml OP Diason RTH Glucerna Select RTH DIABETIC ORAL FEED 1KCAL/ML – Special Authority see SA1095 above – Hospital pharmacy [HP3] Liquid (strawberry) ..............................................................................1.50 200 ml OP Diasip Liquid (vanilla) ....................................................................................1.50 200 ml OP Diasip 1.88 250 ml OP Glucerna Select 1.78 237 ml OP (2.10) Resource Diabetic

Fat Modiﬁed Products

¾SA1096 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Either: 1 Patient has metabolic disorders of fat metabolism; or 2 Patient has chylothorax. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. FAT MODIFIED FEED – Special Authority see SA1096 above – Hospital pharmacy [HP3] Powder ..............................................................................................60.48 400 g OP Monogen

High Protein Products

¾SA1097 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 Anorexia and weight loss; and continued. . .

fully subsidised

[HP3], [HP4] refer page 9

183

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 2 Either: 2.1 decompensating liver disease without encephalopathy; or 2.2 protein losing gastro-enteropathy. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. HIGH PROTEIN ORAL FEED 1KCAL/ML – Special Authority see SA1097 on the preceding page – Hospital pharmacy [HP3] Liquid ..................................................................................................1.90 200 ml OP Fortimel Regular

Paediatric Products For Children Awaiting Liver Transplant

¾SA1098 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years where the patient is a child (up to 18 years) who is awaiting liver transplant. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. ENTERAL/ORAL FEED 1KCAL/ML – Special Authority see SA1098 above – Hospital pharmacy [HP3] Powder ..............................................................................................78.97 400 g OP Generaid Plus

Paediatric Products For Children With Chronic Renal Failure

¾SA1099 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years where the patient is a child (up to 18 years) with chronic renal failure. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. ENTERAL/ORAL FEED 1KCAL/ML – Special Authority see SA1099 above – Hospital pharmacy [HP3] Liquid ................................................................................................54.00 400 g OP Kindergen

Paediatric Products

¾SA1100 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 Infant aged one to eight years; and continued. . .

184

fully subsidised

[HP3], [HP4] refer page 9

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 2 Any of the following: 2.1 any condition causing malabsorption; or 2.2 failure to thrive; or 2.3 increased nutritional requirements. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. PAEDIATRIC ENTERAL FEED 1.5KCAL/ML – Special Authority see SA1100 on the preceding page – Hospital pharmacy [HP3] Liquid ..................................................................................................6.00 500 ml OP Nutrini Energy RTH PAEDIATRIC ENTERAL FEED 1KCAL/ML – Special Authority see SA1100 on the preceding page – Hospital pharmacy [HP3] Liquid ..................................................................................................2.68 500 ml OP Nutrini RTH Pediasure RTH PAEDIATRIC ORAL FEED 1.5KCAL/ML – Special Authority see SA1100 on the preceding page – Hospital pharmacy [HP3] Liquid (strawberry) ..............................................................................1.60 200 ml OP Fortini NutriniDrink Liquid (vanilla) ....................................................................................1.60 200 ml OP Fortini NutriniDrink (NutriniDrink Liquid (strawberry) to be delisted 1 May 2012) (NutriniDrink Liquid (vanilla) to be delisted 1 May 2012) PAEDIATRIC ORAL FEED 1KCAL/ML – Special Authority see SA1100 on the preceding page – Hospital pharmacy [HP3] Liquid (chocolate) ...............................................................................1.07 200 ml OP Pediasure Liquid (strawberry) ..............................................................................1.07 200 ml OP Pediasure Liquid (vanilla) ....................................................................................1.07 200 ml OP Pediasure 1.27 237 ml OP Pediasure PAEDIATRIC ORAL FEED WITH FIBRE 1.5KCAL/ML – Special Authority see SA1100 on the preceding page – Hospital pharmacy [HP3] Liquid (chocolate) ...............................................................................1.60 200 ml OP Fortini Multi Fibre NutriniDrink Multiﬁbre Liquid (strawberry) ..............................................................................1.60 200 ml OP Fortini Multi Fibre NutriniDrink Multiﬁbre Liquid (vanilla) ....................................................................................1.60 200 ml OP Fortini Multi Fibre NutriniDrink Multiﬁbre (NutriniDrink Multiﬁbre Liquid (chocolate) to be delisted 1 May 2012) (NutriniDrink Multiﬁbre Liquid (strawberry) to be delisted 1 May 2012) (NutriniDrink Multiﬁbre Liquid (vanilla) to be delisted 1 May 2012)

fully subsidised

[HP3], [HP4] refer page 9

185

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Renal Products

¾SA1101 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years where the patient has acute or chronic renal failure. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. ENTERAL FEED 2KCAL/ML – Special Authority see SA1101 above – Hospital pharmacy [HP3] Liquid ..................................................................................................6.08 500 ml OP Nutrison Concentrated RENAL ORAL FEED 2KCAL/ML – Special Authority see SA1101 above – Hospital pharmacy [HP3] Liquid ..................................................................................................2.43 200 ml OP Nepro (strawberry) Nepro (vanilla) 2.88 237 ml OP (3.31) NovaSource Renal Liquid (apricot) ....................................................................................2.88 125 ml OP Renilon 7.5 Liquid (caramel) ..................................................................................2.88 125 ml OP Renilon 7.5

Specialised And Elemental Products

¾SA1102 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Any of the following: 1 malabsorption; or 2 short bowel syndrome; or 3 enterocutaneous ﬁstulas; or 4 pancreatitis. Notes: Each of these products is highly specialised and would be prescribed only by an expert for a speciﬁc disorder. The alternative is hospitalisation. Elemental 028 Extra is more expensive than other products listed in this section and should only be used where the alternatives have been tried ﬁrst and/or are unsuitable. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. ENTERAL/ORAL ELEMENTAL FEED 1KCAL/ML – Special Authority see SA1102 above – Hospital pharmacy [HP3] Powder ................................................................................................4.40 79 g OP Vital HN Alitraq 7.50 76 g OP ORAL ELEMENTAL FEED 0.8KCAL/ML – Special Authority see SA1102 above – Hospital pharmacy [HP3] Liquid (grapefruit) ...............................................................................9.50 250 ml OP Elemental 028 Extra Liquid (pineapple & orange) ...............................................................9.50 250 ml OP Elemental 028 Extra Liquid (summer fruit) ..........................................................................9.50 250 ml OP Elemental 028 Extra

186

fully subsidised

[HP3], [HP4] refer page 9

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

ORAL ELEMENTAL FEED 1KCAL/ML – Special Authority see SA1102 on the preceding page – Hospital pharmacy [HP3] Powder (unﬂavoured) .........................................................................4.50 80.4 g OP Vivonex TEN SEMI-ELEMENTAL ENTERAL FEED 1KCAL/ML – Special Authority see SA1102 on the preceding page – Hospital pharmacy [HP3] Liquid ................................................................................................12.04 1,000 ml OP Peptisorb

Undyalised End Stage Renal Failure

¾SA1103 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years where the patient has undialysed end stage renal failure. Note: Where possible, the requirements for oral supplementation should be established in conjunction with assessment by a dietitian. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. RENAL ORAL FEED 1KCAL/ML – Special Authority see SA1103 above – Hospital pharmacy [HP3] Liquid ..................................................................................................3.80 237 ml OP Suplena

Standard Supplements

¾SA1104 Special Authority for Subsidy Initial application — (Children) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 The patient is under 18 years of age; and 2 Any of the following: 2.1 The patient has a condition causing malabsorption; or 2.2 The patient has failure to thrive; or 2.3 The patient has increased nutritional requirements; and 3 Nutrition goal has been set (eg reach a speciﬁc weight or BMI). Renewal — (Children) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 The patient is under 18 years of age; and 2 The treatment remains appropriate and the patient is beneﬁting from treatment; and 3 A nutrition goal has been set (eg reach a speciﬁc weight or BMI). Initial application — (Adults (This category cannot be processed electonically - fax paper copy)) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 months for applications meeting the following criteria: All of the following: 1 Any of the following: Patient is Malnourished 1.1 Patient has a body mass index (BMI) of less than 18.5 kg/m2; or 1.2 Patient has unintentional weight loss greater than 10% within the last 3-6 months; or 1.3 Patient has a BMI of less than 20 kg/m2 and unintentional weight loss greater than 5% within the last 3-6 months; and continued. . .

fully subsidised

[HP3], [HP4] refer page 9

187

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 2 Any of the following: Patient has not responded to ﬁrst-line dietary measures over a 4 week period by: 2.1 Increasing their food intake frequency (eg snacks between meals); or 2.2 Using high-energy foods (e.g. milkshakes, full fat milk, butter, cream, cheese, sugar etc); or 2.3 Using over the counter supplements (e.g. Complan); and 3 A nutrition goal has been set (e.g. to reach a speciﬁc weight or BMI). Renewal — (Adults) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 6 months for applications meeting the following criteria: Both: 1 A nutrition goal has been set (eg reach a speciﬁc weight or BMI); and 2 Any of the following: Patient is Malnourished 2.1 Patient has a body mass index (BMI) of less than 18.5 kg/m2; or 2.2 Patient has unintentional weight loss greater than 10% within the last 3-6 months; or 2.3 Patient has a BMI of less than 20 kg/m2 and unintentional weight loss greater than 5% within the last 3-6 months. Initial application — (Adults transitioning from hospital Discretionary Community Supply) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 The patient has had up to a 30 day supply of a 1.0 or a 1.5 kcal/ml Standard Oral Supplement; and 2 A nutrition goal has been set (eg reach a speciﬁc weight or BMI); and 3 Any of the following: Patient is Malnourished 3.1 Patient has a body mass index (BMI) of less than 18.5 kg/m2; or 3.2 Patient has unintentional weight loss greater than 10% within the last 3-6 months; or 3.3 Patient has a BMI of less than 20 kg/m2 and unintentional weight loss greater than 5% within the last 3-6 months. Initial application — (Speciﬁc medical condition) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Any of the following: 1 Is being feed via a nasogastric tube or a nasogastric tube is to be inserted for feeding; or 2 Malignancy and is considered likely to develop malnutrition as a result; or 3 Is undergoing a bone marrow transplant; or 4 Tempomandibular surgery. Renewal — (Speciﬁc medical condition) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Any of the following: 1 Is being fed via a nasogastric tube; or 2 Malignancy and is considered likely to develop malnutrition as a result; or 3 Has undergone a bone marrow transplant; or 4 Tempomandibular surgery. Initial application — (Chronic disease OR tube feeding) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Any of the following: 1 Is being fed via a tube or a tube is to be inserted for the purpose of feeding (not nasogastric tube - refer to speciﬁc medical condition criteria); or 2 Cystic Fibrosis; or 3 Liver disease; or 4 Chronic Renal failure; or continued. . .

188

fully subsidised

[HP3], [HP4] refer page 9

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 5 Inﬂammatory bowel disease; or 6 Chronic obstructive pulmonary disease with hypercapnia; or 7 Short bowel syndrome; or 8 Bowel ﬁstula; or 9 Severe chronic neurological conditions. Renewal — (Chronic disease OR tube feeding for patients who have previously been funded under Special Authority forms SA0702 or SA0583) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Any of the following: 1 Is being fed via a tube or a tube is to be inserted for the purpose of feeding (not nasogastric tube - refer to speciﬁc medical condition criteria); or 2 Cystic Fibrosis; or 3 Liver disease; or 4 Chronic Renal failure; or 5 Inﬂammatory bowel disease; or 6 Chronic obstructive pulmonary disease with hypercapnia; or 7 Short bowel syndrome; or 8 Bowel ﬁstula; or 9 Severe chronic neurological conditions. ENTERAL FEED 1KCAL/ML – Special Authority see SA1104 on page 187 – Hospital pharmacy [HP3] Liquid ..................................................................................................1.24 250 ml OP Isosource Standard Osmolite 2.65 500 ml OP Nutrison Standard RTH 5.29 1,000 ml OP Nutrison Standard RTH Isosource Standard RTH 2.65 500 ml OP Osmolite RTH 5.29 1,000 ml OP Osmolite RTH ENTERAL FEED WITH FIBRE 1 KCAL/ML – Special Authority see SA1104 on page 187 – Hospital pharmacy [HP3] Liquid ..................................................................................................1.32 237 ml OP Jevity 2.65 500 ml OP Nutrison Multi Fibre 5.29 1,000 ml OP Nutrison Multi Fibre 2.65 500 ml OP Jevity RTH 5.29 1,000 ml OP Jevity RTH ENTERAL FEED WITH FIBRE 1.5KCAL/ML – Special Authority see SA1104 on page 187 – Hospital pharmacy [HP3] Liquid ..................................................................................................1.75 250 ml OP Ensure Plus HN 7.00 1,000 ml OP Ensure Plus RTH Nutrison Energy Multi Fibre

fully subsidised

[HP3], [HP4] refer page 9

189

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

ORAL FEED 1 KCAL/ML – Special Authority see SA1104 on page 187 – Hospital pharmacy [HP3] Powder (chocolate) .............................................................................9.50 900 g OP Ensure 10.22 Sustagen Hospital Formula Powder (strawberry) ..........................................................................4.22 400 g OP Ensure Powder (vanilla) ..................................................................................9.50 900 g OP Ensure 10.22 Sustagen Hospital Formula (Ensure Powder (strawberry) to be delisted 1 March 2012) ORAL FEED 1.5KCAL/ML – Special Authority see SA1104 on page 187 – Hospital pharmacy [HP3] Additional subsidy by endorsement is available for patients being bolus fed through a feeding tube. The prescription must be endorsed accordingly. Liquid (banana) – Higher subsidy of $1.26 per 200 ml with Endorsement ................................................................................ 0.72 200 ml OP (1.26) Ensure Plus (1.26) Fortisip Liquid (chocolate) – Higher subsidy of up to $1.33 per 237 ml with Endorsement......................................................................... 0.72 200 ml OP (1.26) Ensure Plus 0.85 237 ml OP (1.33) Ensure Plus 0.72 200 ml OP (1.26) Fortisip Liquid (coffee latte) – Higher subsidy of up to $1.33 per 237 ml with Endorsement............................................................. 0.85 237 ml OP (1.33) Ensure Plus Liquid (fruit of the forest) – Higher subsidy of $1.26 per 200 ml with Endorsement......................................................................... 0.72 200 ml OP (1.26) Ensure Plus Liquid (strawberry) – Higher subsidy of up to $1.33 per 237 ml with Endorsement............................................................. 0.72 200 ml OP (1.26) Ensure Plus 0.85 237 ml OP (1.33) Ensure Plus 0.72 200 ml OP (1.26) Fortisip Liquid (toffee) – Higher subsidy of $1.26 per 200 ml with Endorsement..................................................................................... 0.72 200 ml OP (1.26) Fortisip Liquid (tropical fruit) – Higher subsidy of $1.26 per 200 ml with Endorsement......................................................................... 0.72 200 ml OP (1.26) Fortisip Liquid (vanilla) – Higher subsidy of up to $1.33 per 237 ml with Endorsement......................................................................... 0.72 200 ml OP (1.26) Ensure Plus 0.85 237 ml OP (1.33) Ensure Plus 0.72 200 ml OP (1.26) Fortisip (Ensure Plus Liquid (coffee latte) to be delisted 1 March 2012)

190

fully subsidised

[HP3], [HP4] refer page 9

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

ORAL FEED WITH FIBRE 1.5 KCAL/ML – Special Authority see SA1104 on page 187 – Hospital pharmacy [HP3] Additional subsidy by endorsement is available for patients being bolus fed through a feeding tube. The prescription must be endorsed accordingly. Liquid (chocolate) – Higher subsidy of $1.26 per 200 ml with Endorsement ................................................................................0.72 200 ml OP (1.26) Fortisip Multi Fibre Liquid (strawberry) – Higher subsidy of $1.26 per 200 ml with Endorsement ................................................................................0.72 200 ml OP (1.26) Fortisip Multi Fibre Liquid (vanilla) – Higher subsidy of $1.26 per 200 ml with Endorsement ................................................................................0.72 200 ml OP (1.26) Fortisip Multi Fibre

Adult Products High Calorie

¾SA1105 Special Authority for Subsidy Initial application — (Cystic ﬁbrosis) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: All of the following: 1 Cystic ﬁbrosis; and 2 other lower calorie products have been tried; and 3 patient has substantially increased metabolic requirements. Initial application — (Indications other than cystic ﬁbrosis) only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: All of the following: 1 Any of the following: 1.1 any condition causing malabsorption; or 1.2 failure to thrive; or 1.3 increased nutritional requirements; and 2 other lower calorie products have been tried; and 3 patient has substantially increased metabolic requirements. Renewal — (Cystic ﬁbrosis) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 3 years for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. Renewal — (Indications other than cystic ﬁbrosis) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. ORAL FEED 2KCAL/ML – Special Authority see SA1105 above – Hospital pharmacy [HP3] Additional subsidy by endorsement is available for patients being bolus fed through a feeding tube. The prescription must be endorsed accordingly. Liquid (vanilla) – Higher subsidy of $2.25 per 237 ml with Endorsement ................................................................................1.14 237 ml OP (2.25) Two Cal HN

fully subsidised

[HP3], [HP4] refer page 9

191

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Food Thickeners

¾SA1106 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year where the patient has motor neurone disease with swallowing disorder. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. FOOD THICKENER – Special Authority see SA1106 above – Hospital pharmacy [HP3] Powder ................................................................................................7.25 380 g OP Karicare Food Thickener

Gluten Free Foods

The funding of gluten free foods is no longer being actively managed by PHARMAC from 1 April 2011. This means that we are no longer considering the listing of new products, or making subsidy, or other changes to the existing listings. As a result we anticipate that the range of funded items will reduce over time. Management of Coeliac disease with a gluten free diet is necessary for good outcomes. A range of gluten free options are available through retail outlets. ¾SA1107 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Either: 1 Gluten enteropathy has been diagnosed by biopsy; or 2 Patient suffers from dermatitis herpetiformis. GLUTEN FREE BAKING MIX – Special Authority see SA1107 above – Hospital pharmacy [HP3] Powder ................................................................................................2.81 1,000 g OP (5.15) Healtheries Simple Baking Mix GLUTEN FREE BREAD MIX – Special Authority see SA1107 above – Hospital pharmacy [HP3] Powder ................................................................................................3.93 1,000 g OP (7.32) 4.77 (8.71) 3.51 (10.87) GLUTEN FREE FLOUR – Special Authority see SA1107 above – Hospital pharmacy [HP3] Powder ................................................................................................5.62 2,000 g OP (18.10)

NZB Low Gluten Bread Mix Bakels Gluten Free Health Bread Mix Horleys Bread Mix

Horleys Flour

192

fully subsidised

[HP3], [HP4] refer page 9

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

GLUTEN FREE PASTA – Special Authority see SA1107 on the preceding page – Hospital pharmacy [HP3] Buckwheat Spirals ..............................................................................2.00 250 g OP (3.11) Orgran Corn and Vegetable Shells .................................................................2.00 250 g OP (2.92) Orgran Corn and Vegetable Spirals ................................................................2.00 250 g OP (2.92) Orgran Rice and Corn Lasagne Sheets .........................................................1.60 200 g OP (3.82) Orgran Rice and Corn Macaroni .....................................................................2.00 250 g OP (2.92) Orgran Rice and Corn Penne .........................................................................2.00 250 g OP (2.92) Orgran Rice and Maize Pasta Spirals .............................................................2.00 250 g OP (2.92) Orgran Rice and Millet Spirals ........................................................................2.00 250 g OP (3.11) Orgran Rice and corn spaghetti noodles ........................................................2.00 375 g OP (2.92) Orgran Vegetable and Rice Spirals ................................................................2.00 250 g OP (2.92) Orgran Italian long style spaghetti ..................................................................2.00 220 g OP (3.11) Orgran

Foods And Supplements For Inborn Errors Of Metabolism

¾SA1108 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid without further renewal unless notiﬁed for applications meeting the following criteria: Any of the following: 1 Dietary management of homocystinuria; or 2 Dietary management of maple syrup urine disease; or 3 Dietary management of phenylketonuria (PKU); or 4 For use as a supplement to the Ketogenic diet in patients diagnosed with epilepsy.

Supplements For Homocystinuria

AMINOACID FORMULA WITHOUT METHIONINE – Special Authority see SA1108 above – Hospital pharmacy [HP3] Powder ............................................................................................461.94 500 g OP XMET Maxamum

Supplements For MSUD

AMINOACID FORMULA WITHOUT VALINE, LEUCINE AND ISOLEUCINE – Special Authority see SA1108 above – Hospital pharmacy [HP3] Powder ............................................................................................300.54 500 g OP MSUD Maxamaid 437.22 MSUD Maxamum

fully subsidised

[HP3], [HP4] refer page 9

193

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

Supplements For PKU

AMINOACID FORMULA WITHOUT PHENYLALANINE – Special Authority see SA1108 on the preceding page – Hospital pharmacy [HP3] Tabs ..................................................................................................99.00 75 OP Phlexy 10 Sachets (pineapple/vanilla) 29 g ....................................................330.10 30 OP Minaphlex Sachets (tropical) ............................................................................324.00 30 Phlexy 10 Infant formula ..................................................................................174.72 400 g OP PKU Anamix Infant Powder (orange) .............................................................................221.00 500 g OP XP Maxamaid 320.00 XP Maxamum Powder (unﬂavoured) .....................................................................221.00 500 g OP XP Maxamaid 320.00 XP Maxamum Liquid (berry) ....................................................................................15.65 62.5 ml OP PKU Lophlex LQ 31.20 125 ml OP PKU Lophlex LQ Liquid (citrus) ....................................................................................15.65 62.5 ml OP PKU Lophlex LQ 31.20 125 ml OP PKU Lophlex LQ Liquid (forest berries) ........................................................................30.00 250 ml OP Easiphen Liquid Liquid (orange) .................................................................................15.65 62.5 ml OP PKU Lophlex LQ 31.20 125 ml OP PKU Lophlex LQ Liquid (tropical) ................................................................................30.00 250 ml OP Easiphen (Easiphen Liquid (tropical) to be delisted 1 May 2012)

Foods

LOW PROTEIN BAKING MIX – Special Authority see SA1108 on the preceding page – Hospital pharmacy [HP3] Powder ................................................................................................8.22 500 g OP Loproﬁn Mix LOW PROTEIN PASTA – Special Authority see SA1108 on the preceding page – Hospital pharmacy [HP3] Animal shapes ..................................................................................11.91 500 g OP Loproﬁn Lasagne ..............................................................................................5.95 250 g OP Loproﬁn Low protein rice pasta ......................................................................11.91 500 g OP Loproﬁn Macaroni .............................................................................................5.95 250 g OP Loproﬁn Penne ...............................................................................................11.91 500 g OP Loproﬁn Spaghetti ..........................................................................................11.91 500 g OP Loproﬁn Spirals ...............................................................................................11.91 500 g OP Loproﬁn

Multivitamin And Mineral Supplements

AMINOACID FORMULA WITH MINERALS WITHOUT PHENYLALANINE – Special Authority see SA1108 on the preceding page – Retail pharmacy Powder .............................................................................................23.38 100 g OP Metabolic Mineral Mixture (Metabolic Mineral Mixture Powder to be delisted 1 May 2012)

Infant Formulae For Premature Infants

¾SA1109 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 6 months where the patient is infant weighing less than 1.5 kg at birth. PREMATURE BIRTH FORMULA – Special Authority see SA1109 above – Hospital pharmacy [HP3] Liquid ..................................................................................................0.75 100 ml OP S26LBW Gold RTF

194

fully subsidised

[HP3], [HP4] refer page 9

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

For Williams Syndrome

¾SA1110 Special Authority for Subsidy Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year where the patient is an infant suffering from Williams Syndrome and associated hypercalcaemia. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 1 year for applications meeting the following criteria: Both: 1 The treatment remains appropriate and the patient is beneﬁting from treatment; and 2 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. LOW CALCIUM INFANT FORMULA – Special Authority see SA1110 above – Hospital pharmacy [HP3] Powder ..............................................................................................44.40 400 g OP Locasol

Gastrointestinal and Other Malabsorptive Problems

AMINO ACID FORMULA – Special Authority see SA1111 below – Hospital pharmacy [HP3] Powder ................................................................................................6.00 48.5 g OP 56.00 400 g OP Powder (tropical) ...............................................................................56.00 Powder (unﬂavoured) .......................................................................56.00 400 g OP 400 g OP

Powder (vanilla) ................................................................................56.00

400 g OP

Vivonex Pediatric Neocate Neocate LCP Neocate Advance Elecare Elecare LCP Neocate Advance Elecare

¾SA1111 Special Authority for Subsidy Initial application — (Transition from Old Form (SA0603)) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 The patient is currently receiving funded amino acid formula under Special Authority form SA0603; and 2 An assessment as to whether the infant can be transitioned to a cows milk protein, soy, or extensively hydrolysed infant formula has been undertaken; and 3 The outcome of the assessment is that the infant continues to require an amino acid infant formula; and 4 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and the date contacted. Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 6 months for applications meeting the following criteria: Any of the following: 1 Extensively hydrolysed formula has been reasonably trialled and is inappropriate due to documented severe intolerance or allergy or malabsorption; or 2 History of anaphylaxis to cows milk protein formula or dairy products; or 3 Eosinophilic oesophagitis. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 An assessment as to whether the infant can be transitioned to a cows milk protein, soy, or extensively hydrolysed infant formula has been undertaken; and continued. . .

fully subsidised

[HP3], [HP4] refer page 9

195

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 2 The outcome of the assessment is that the infant continues to require an amino acid infant formula; and 3 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. EXTENSIVELY HYDROLYSED FORMULA – Special Authority see SA1112 below – Hospital pharmacy [HP3] Powder ..............................................................................................15.21 450 g OP Pepti Junior Gold ¾SA1112 Special Authority for Subsidy Initial application — (Transition from Old Form (SA0603)) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 6 months for applications meeting the following criteria: Either: 1 All of the following: 1.1 The infant is currently receiving funded amino acid formula under Special Authority form SA0603; and 1.2 The infant is to be trialled on, or transitioned to, an extensively hydrolysed formula; and 1.3 General Practitioners must include the name of the relevant specialist or vocationally registered general practitioner and the date contacted; or 2 All of the following: 2.1 The patient is currently receiving funded extensively hydrolysed formula under Special Authority form SA0603; and 2.2 An assessment as to whether the infant can be transitioned to a cows milk protein or soy infant formula has been undertaken; and 2.3 The outcome of the assessment is that the infant continues to require an extensively hydrolysed infant formula; and 2.4 General Practitioners must include the name of the relevant specialist or vocationally registered general practitioner and the date contacted. Initial application only from a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 6 months for applications meeting the following criteria: Any of the following: 1 Both: 1.1 Cows milk formula is inappropriate due to severe intolerance or allergy to its protein content; and 1.2 Either: 1.2.1 Soy milk formula has been trialled without resolution of symptoms; or 1.2.2 Soy milk formula is considered clinically inappropriate or contraindicated; or 2 Severe malabsorption; or 3 Short bowel syndrome; or 4 Intractable diarrhea; or 5 Biliary atresia; or 6 Cholestatic liver diseases causing malsorption; or 7 Chylous ascite; or 8 Chylothorax; or 9 Cystic ﬁbrosis; or 10 Proven fat malabsorption; or 11 Severe intestinal motility disorders causing signiﬁcant malabsorption; or 12 Intestinal failure. Renewal only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 An assessment as to whether the infant can be transitioned to a cows milk protein or soy infant formula has been undertaken; and 2 The outcome of the assessment is that the infant continues to require an extensively hydrolysed infant formula; and continued. . .

196

fully subsidised

[HP3], [HP4] refer page 9

SPECIAL FOODS

Subsidy (Manufacturer’s Price) $ Fully Subsidised Per Brand or Generic Manufacturer

continued. . . 3 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and date contacted. Renewal — (Step Down from Amino Acid Formula) only from a dietitian, relevant specialist, vocationally registered general practitioner or general practitioner on the recommendation of a dietitian, relevant specialist or vocationally registered general practitioner. Approvals valid for 6 months for applications meeting the following criteria: All of the following: 1 The infant is currently receiving funded amino acid formula; and 2 The infant is to be trialled on, or transitioned to, an extensively hydrolysed formula; and 3 General Practitioners must include the name of the dietitian, relevant specialist or vocationally registered general practitioner and the date contacted.

fully subsidised

[HP3], [HP4] refer page 9

197

SECTION E PART I PRACTITIONER’S SUPPLY ORDERS Pharmaceuticals and quantities that may be obtained on a Practitioner’s Supply Order

ADRENALINE Inj 1 in 1,000, 1 ml ...................................................... 5 Inj 1 in 10,000, 10 ml .................................................. 5 AMINOPHYLLINE Inj 25 mg per ml, 10 ml ............................................... 5 AMIODARONE HYDROCHLORIDE Inj 50 mg per ml, 3 ml ................................................. 5 AMOXYCILLIN Cap 250 mg .............................................................. 30 Grans for oral liq 125 mg per 5 ml ..................... 200 ml Grans for oral liq 250 mg per 5 ml ..................... 200 ml Inj 1 g.......................................................................... 5 AMOXYCILLIN CLAVULANATE Tab amoxycillin 500 mg with potassium clavulanate 125 mg ..............................................30 Grans for oral liq amoxycillin 125 mg with potassium clavulanate 31.25 mg per 5 ml................................................................ 200 ml Grans for oral liq amoxycillin 250 mg with potassium clavulanate 62.5 mg per 5 ml................................................................ 200 ml ASPIRIN Tab dispersible 300 mg............................................. 30 ATROPINE SULPHATE Inj 600 µg, 1 ml ........................................................... 5 AZITHROMYCIN Tab 500 mg – Subsidy by endorsement – See note on page 80 ..............................................8 BENDROFLUAZIDE Tab 2.5 mg – See note on page 54......................... 150 BENZATHINE BENZYLPENICILLIN Inj 1.2 mega u per 2.3 ml ............................................ 5 BENZTROPINE MESYLATE Inj 1 mg per ml, 2 ml ................................................... 5 BENZYLPENICILLIN SODIUM (PENICILLIN G) Inj 600 mg ................................................................... 5 CEFTRIAXONE SODIUM Inj 500 mg – Subsidy by endorsement – See note on page 79 .....................................................5 Inj 1 g – Subsidy by endorsement – See note on page 79 .....................................................5 CHARCOAL Oral liq 50 g per 250 ml ..................................... 250 ml CHLORPROMAZINE HYDROCHLORIDE Tab 10 mg ................................................................. 30 Tab 25 mg ................................................................. 30 Tab 100 mg ............................................................... 30 Inj 25 mg per ml, 2 ml ................................................. 5 CIPROFLOXACIN Tab 250 mg ................................................................. 5 Tab 500 mg ................................................................. 5 CO-TRIMOXAZOLE Tab trimethoprim 80 mg and sulphamethoxazole 400 mg..................................30 Oral liq trimethoprim 40 mg and sulphamethoxazole 200 mg per 5 ml................................................................ 200 ml COMPOUND ELECTROLYTES Powder for soln for oral use 4.4 g ............................. 10 CONDOMS 49 mm..................................................................... 144 52 mm..................................................................... 144 52 mm extra strength.............................................. 144 53 mm..................................................................... 144 53 mm (chocolate) .................................................. 144 53 mm (strawberry)................................................. 144 53 mm extra strength.............................................. 144 54 mm, shaped ....................................................... 144 55 mm..................................................................... 144 56 mm..................................................................... 144 56 mm, shaped ....................................................... 144 60 mm..................................................................... 144 DEXAMETHASONE Tab 1 mg – Retail pharmacy-Specialist .................... 30 Tab 4 mg – Retail pharmacy-Specialist .................... 30 DEXAMETHASONE SODIUM PHOSPHATE Inj 4 mg per ml, 1 ml – See note on page 72.............. 5 Inj 4 mg per ml, 2 ml – See note on page 72.............. 5 DEXTROSE Inj 50%, 10 ml ............................................................. 5 Inj 50%, 90 ml ............................................................. 5 DIAPHRAGM 65 mm – See note on page 66 ................................... 1 70 mm – See note on page 66 ................................... 1 75 mm – See note on page 66 ................................... 1 80 mm – See note on page 66 ................................... 1 continued. . .

198

fully subsidised brand available Please refer to Section A for a deﬁnition, and conditions of supply, of Practitioner’s Supply Orders.

PRACTITIONER’S SUPPLY ORDERS

(continued) DIAZEPAM Inj 5 mg per ml, 2 ml – Subsidy by endorsement – See note on page 121 ...................5 Rectal tubes 5 mg....................................................... 5 Rectal tubes 10 mg..................................................... 5 DICLOFENAC SODIUM Inj 25 mg per ml, 3 ml ................................................. 5 Suppos 50 mg........................................................... 10 DIGOXIN Tab 62.5 µg ............................................................... 30 Tab 250 µg ................................................................ 30 DOXYCYCLINE HYDROCHLORIDE Tab 50 mg ................................................................. 30 Tab 100 mg ............................................................... 30 ERGOMETRINE MALEATE Inj 500 µg per ml, 1 ml ................................................ 5 ERYTHROMYCIN ETHYL SUCCINATE Tab 400 mg ............................................................... 30 Grans for oral liq 200 mg per 5 ml ..................... 200 ml Grans for oral liq 400 mg per 5 ml ..................... 200 ml ERYTHROMYCIN STEARATE Tab 250 mg ............................................................... 30 ETHINYLOESTRADIOL WITH DESOGESTREL Tab 20 µg with desogestrel 150 µg ........................... 63 Tab 20 µg with desogestrel 150 µg and 7 inert tab ................................................................84 Tab 30 µg with desogestrel 150 µg ........................... 63 Tab 30 µg with desogestrel 150 µg and 7 inert tab ................................................................84 ETHINYLOESTRADIOL WITH LEVONORGESTREL Tab 50 µg with levonorgestrel 125 µg and 7 inert tab ................................................................84 Tab 30 µg with levonorgestrel 150 µg ....................... 63 Tab 30 µg with levonorgestrel 150 µg and 7 inert tab ................................................................84 Tab 20 µg with levonorgestrel 100 µg and 7 inert tab ................................................................84 ETHINYLOESTRADIOL WITH NORETHISTERONE Tab 35 µg with norethisterone 1 mg.......................... 63 Tab 35 µg with norethisterone 1 mg and 7 inert tab ................................................................84 Tab 35 µg with norethisterone 500 µg....................... 63 Tab 35 µg with norethisterone 500 µg and 7 inert tab ................................................................84 FLUCLOXACILLIN SODIUM Cap 250 mg .............................................................. 30 Grans for oral liq 125 mg per 5 ml ..................... 200 ml Grans for oral liq 250 mg per 5 ml ..................... 200 ml Inj 1 g.......................................................................... 5 FLUPENTHIXOL DECANOATE Inj 20 mg per ml, 1 ml ................................................. 5 Inj 20 mg per ml, 2 ml ................................................. 5 Inj 100 mg per ml, 1 ml ............................................... 5 FLUPHENAZINE DECANOATE Inj 12.5 mg per 0.5 ml, 0.5 ml ..................................... 5 Inj 25 mg per ml, 1 ml ................................................. 5 Inj 100 mg per ml, 1 ml ............................................... 5 FUROSEMIDE Tab 40 mg ................................................................. 30 Inj 10 mg per ml, 2 ml ................................................. 5 GLUCAGON HYDROCHLORIDE Inj 1 mg syringe kit...................................................... 5 GLYCERYL TRINITRATE Tab 600 µg .............................................................. 100 Oral pump spray 400 µg per dose ................. 250 dose HALOPERIDOL Tab 500 µg ................................................................ 30 Tab 1.5 mg ................................................................ 30 Tab 5 mg ................................................................... 30 Oral liq 2 mg per ml ........................................... 200 ml Inj 5 mg per ml, 1 ml ................................................... 5 HALOPERIDOL DECANOATE Inj 50 mg per ml, 1 ml ................................................. 5 Inj 100 mg per ml, 1 ml ............................................... 5 HYDROCORTISONE Inj 50 mg per ml, 2 ml ................................................. 5 HYDROXOCOBALAMIN Inj 1 mg per ml, 1 ml ................................................... 6 HYOSCINE N-BUTYLBROMIDE Inj 20 mg, 1 ml ............................................................ 5 INTRA-UTERINE DEVICE IUD............................................................................ 40 IPRATROPIUM BROMIDE Nebuliser soln, 250 µg per ml, 1 ml .......................... 40 Nebuliser soln, 250 µg per ml, 2 ml .......................... 40 LEVONORGESTREL Tab 30 µg .................................................................. 84 Tab 1.5 mg .................................................................. 5 continued. . .

fully subsidised brand available Please refer to Section A for a deﬁnition, and conditions of supply, of Practitioner’s Supply Orders.

199

PRACTITIONER’S SUPPLY ORDERS

(continued) LIGNOCAINE Gel 2%, 10 ml urethral syringe – Subsidy by endorsement – See note on page 115 ...................5 LIGNOCAINE HYDROCHLORIDE Inj 1%, 5 ml ................................................................. 5 Inj 2%, 5 ml ................................................................. 5 Inj 1%, 20 ml ............................................................... 5 Inj 2%, 20 ml ............................................................... 5 LIGNOCAINE WITH CHLORHEXIDINE Gel 2% with chlorhexidine 0.05%, 10 ml urethral syringes – Subsidy by endorsement – See note on page 115 ...................5 LOPERAMIDE HYDROCHLORIDE Tab 2 mg ................................................................... 30 Cap 2 mg .................................................................. 30 MASK FOR SPACER DEVICE Size 2 – See note on page 165 ................................ 20 MEDROXYPROGESTERONE ACETATE Inj 150 mg per ml, 1 ml syringe................................... 5 METOCLOPRAMIDE HYDROCHLORIDE Inj 5 mg per ml, 2 ml ................................................... 5 METRONIDAZOLE Tab 200 mg ............................................................... 30 MORPHINE SULPHATE Inj 5 mg per ml, 1 ml – Only on a controlled drug form ................................................................5 Inj 10 mg per ml, 1 ml – Only on a controlled drug form ................................................................5 Inj 15 mg per ml, 1 ml – Only on a controlled drug form ................................................................5 Inj 30 mg per ml, 1 ml – Only on a controlled drug form ................................................................5 NALOXONE HYDROCHLORIDE Inj 400 µg per ml, 1 ml ................................................ 5 NICOTINE Patch 7 mg – See note on page 139 ........................ 28 Patch 14 mg – See note on page 139 ...................... 28 Patch 21 mg – See note on page 139 ...................... 28 Lozenge 1 mg – See note on page 139.................. 216 Lozenge 2 mg – See note on page 139.................. 216 Gum 2 mg (Classic) – See note on page 139......... 384 Gum 2 mg (Fruit) – See note on page 139 ............. 384 Gum 2 mg (Mint) – See note on page 139 ............. 384 Gum 4 mg (Classic) – See note on page 139......... 384 Gum 4 mg (Fruit) – See note on page 139 ............. 384 Gum 4 mg (Mint) – See note on page 139 ............. 384 NORETHISTERONE Tab 350 µg ................................................................ 84 Tab 5 mg ................................................................... 30 NORETHISTERONE WITH MESTRANOL Tab 1 mg with mestranol 50 µg and 7 inert tab......... 84 OXYTOCIN Inj 5 iu per ml, 1 ml ..................................................... 5 Inj 10 iu per ml, 1 ml ................................................... 5 Inj 5 iu with ergometrine maleate 500 µg per ml, 1 ml...................................................................5 PARACETAMOL Tab 500 mg ............................................................... 30 Oral liq 120 mg per 5 ml .................................... 200 ml Oral liq 250 mg per 5 ml .................................... 100 ml PEAK FLOW METER Low range ................................................................. 10 Normal range............................................................ 10 PETHIDINE HYDROCHLORIDE Inj 50 mg per ml, 1 ml – Only on a controlled drug form ................................................................5 Inj 50 mg per ml, 2 ml – Only on a controlled drug form ................................................................5 PHENOXYMETHYLPENICILLIN (PENICILLIN V) Cap potassium salt 250 mg ...................................... 30 Grans for oral liq 125 mg per 5 ml ..................... 200 ml Grans for oral liq 250 mg per 5 ml ..................... 200 ml PHENYTOIN SODIUM Inj 50 mg per ml, 2 ml ................................................. 5 Inj 50 mg per ml, 5 ml ................................................. 5 PHYTOMENADIONE Inj 2 mg per 0.2 ml ...................................................... 5 Inj 10 mg per ml, 1 ml ................................................. 5 PIPOTHIAZINE PALMITATE Inj 50 mg per ml, 1 ml ................................................. 5 Inj 50 mg per ml, 2 ml ................................................. 5 PREDNISOLONE SODIUM PHOSPHATE Oral liq 5 mg per ml – See note on page 73 ........................................................... 30 ml PREDNISONE Tab 5 mg ................................................................... 30 PREGNANCY TESTS - HCG URINE Cassette........................................................... 200 test PROCAINE PENICILLIN Inj 1.5 mega u ............................................................. 5 continued. . .

200

fully subsidised brand available Please refer to Section A for a deﬁnition, and conditions of supply, of Practitioner’s Supply Orders.

PRACTITIONER’S SUPPLY ORDERS

(continued) PROCHLORPERAZINE Tab 5 mg ................................................................... 30 Inj 12.5 mg per ml, 1 ml .............................................. 5 PROMETHAZINE HYDROCHLORIDE Inj 25 mg per ml, 2 ml ................................................. 5 SALBUTAMOL Inj 500 µg per ml, 1 ml ................................................ 5 Aerosol inhaler, 100 µg per dose CFC free .......................................................... 1000 dose Nebuliser soln, 1 mg per ml, 2.5 ml .......................... 30 Nebuliser soln, 2 mg per ml, 2.5 ml .......................... 30 SALBUTAMOL WITH IPRATROPIUM BROMIDE Nebuliser soln, 2.5 mg with ipratropium bromide 0.5 mg per vial, 2.5 ml ............................20 SILVER SULPHADIAZINE Crm 1%................................................................ 250 g SODIUM BICARBONATE Inj 8.4%, 50 ml ............................................................ 5 Inj 8.4%, 100 ml .......................................................... 5 SODIUM CHLORIDE Inf 0.9% – See note on page 43 ...................... 2000 ml Inj 0.9%, 5 ml – See note on page 43......................... 5 Inj 0.9%, 10 ml – See note on page 43....................... 5 SPACER DEVICE 230 ml (single patient) .............................................. 20 800 ml ....................................................................... 20 SPACER DEVICE AUTOCLAVABLE 230 ml (autoclavable) – Subsidy by endorsement – See note on page 165 ...................5 TRIMETHOPRIM Tab 300 mg ............................................................... 30 VERAPAMIL HYDROCHLORIDE Inj 2.5 mg per ml, 2 ml ................................................ 5 WATER Puriﬁed for inj, 5 ml – See note on page 44................ 5 Puriﬁed for inj, 10 ml – See note on page 44.............. 5 Puriﬁed for inj, 20 ml – See note on page 44.............. 5 ZUCLOPENTHIXOL DECANOATE Inj 200 mg per ml, 1 ml ............................................... 5

fully subsidised brand available Please refer to Section A for a deﬁnition, and conditions of supply, of Practitioner’s Supply Orders.

201

SECTION E PART II: RURAL AREAS

Rural Areas for Practitioner’s Supply Orders

NORTH ISLAND Northland DHB Dargaville Hikurangi Kaeo Kaikohe Kaitaia Kawakawa Kerikeri Mangonui Maungaturoto Moerewa Ngunguru Paihia Rawene Ruakaka Russell Tutukaka Waipu Whangaroa Waitemata DHB Helensville Huapai Kumeu Snells Beach Waimauku Warkworth Wellsford Auckland DHB Great Barrier Island Oneroa Ostend Counties Manukau DHB Tuakau Waiuku Waikato DHB Coromandel Huntly Kawhia Matamata Morrinsville Ngatea Otorohanga Paeroa Pauanui Beach Putaruru Raglan Tairua Taumarunui Te Aroha Te Kauwhata Te Kuiti Tokoroa Waihi Whangamata Whitianga Bay of Plenty DHB Edgecumbe Katikati Kawerau Murupara Opotiki Taneatua Te Kaha Waihi Beach Whakatane Lakes DHB Mangakino Turangi Tairawhiti DHB Ruatoria Te Araroa Te Karaka Te Puia Springs Tikitiki Tokomaru Bay Tolaga Bay Taranaki DHB Eltham Inglewood Manaia Oakura Okato Opunake Patea Stratford Waverley Hawkes Bay DHB Chatham Islands Waipawa Waipukurau Wairoa Whanganui DHB Bulls Marton Ohakune Raetihi Taihape Waiouru MidCentral DHB Dannevirke Foxton Levin Otaki Pahiatua Shannon Woodville Wairarapa DHB Carteron Featherston Greytown Martinborough SOUTH ISLAND Nelson/Marlborough DHB Havelock Mapua Motueka Murchison Picton Takaka Wakeﬁeld West Coast DHB Dobson Greymouth Hokitika Karamea Reefton South Westland Westport Whataroa Canterbury DHB Akaroa Amberley Amuri Cheviot Darﬁeld Diamond Harbour Hanmer Springs Kaikoura Leeston Lincoln Methven Oxford Rakaia Rolleston Rotherham Templeton Waikari

South Canterbury DHB Fairlie Geraldine Pleasant Point Temuka Twizel Waimate

Southern DHB Alexandra Balclutha Cromwell Gore Kurow Lawrence Lumsden Mataura Milton Oamaru Oban Otautau Outram Owaka Palmerston Queenstown Ranfurly Riverton Roxburgh Tapanui Te Anau Tokonui Tuatapere Wanaka Winton

202

fully subsidised brand available Please refer to Section A for a deﬁnition, and conditions of supply, of Practitioner’s Supply Orders.

SECTION F: COMMUNITY PHARMACEUTICALS DISPENSING PERIOD EXEMPTIONS SECTION F: PART I

A Community Pharmaceutical identiﬁed with a F within the other sections of the Pharmaceutical Schedule: a) is exempt from any requirement to dispense in Monthly Lots; b) will only be subsidised if it is dispensed in a 90 Day Lot unless it is Close Control. A Community Pharmaceutical that is an oral contraceptive and that is identiﬁed with a F within the other sections of the Pharmaceutical Schedule: a) is exempt from any requirement to dispense in Monthly Lots; b) will only be subsidised if it is dispensed in a 180 Day Lot unless it is Close Control.

SECTION F: PART II: CERTIFIED EXEMPTIONS AND ACCESS EXEMPTIONS TO MONTHLY DISPENSING

A Community Pharmaceutical, other than a Community Pharmaceutical identiﬁed with a F within the other sections of the Pharmaceutical Schedule, may be dispensed in a 90 Day Lot if: a) the Community Pharmaceutical is identiﬁed with a L within the other sections of the Pharmaceutical Schedule and the prescriber has endorsed the Prescription item(s) on the Prescription to which the exemption applies “certiﬁed exemption”. In endorsing the Prescription items for a certiﬁed exemption, the prescriber is certifying that: i) the patient wished to have the medicine dispensed in a quantity greater than a Monthly Lot; and ii) the patient has been stabilised on the same medicine for a reasonable period of time; and iii) the prescriber has reason to believe the patient will continue on the medicine and is compliant. b) a patient, who has difﬁculty getting to and from a pharmacy, signs the back of the Prescription to qualify for an Access Exemption. In signing the Prescription, the patient or his or her nominated representative must also certify which of the following criteria they meet: i) have limited physical mobility; ii) live and work more than 30 minutes from the nearest pharmacy by their normal form of transport; iii) are relocating to another area; iv) are travelling extensively and will be out of town when the repeat prescriptions are due. The following Community Pharmaceuticals are identiﬁed with a L within the other sections of the Pharmaceutical Schedule and may be dispensed in a 90 Day Lot if endorsed as a certiﬁed exemption in accordance with paragraph (a) in Section F Part II above.

203

SECTION F: PART II

ALIMENTARY TRACT AND METABOLISM INSULIN ASPART INSULIN GLARGINE INSULIN GLULISINE INSULIN ISOPHANE INSULIN ISOPHANE WITH INSULIN NEUTRAL INSULIN LISPRO INSULIN LISPRO WITH INSULIN LISPRO PROTAMINE INSULIN NEUTRAL

MUSCULOSKELETAL SYSTEM PYRIDOSTIGMINE BROMIDE

NERVOUS SYSTEM AMANTADINE HYDROCHLORIDE APOMORPHINE HYDROCHLORIDE ENTACAPONE GABAPENTIN GABAPENTIN (NEURONTIN) LACOSAMIDE

CARDIOVASCULAR SYSTEM AMIODARONE HYDROCHLORIDE Tab 100 mg Cordarone-X Tab 200 mg Cordarone-X DISOPYRAMIDE PHOSPHATE FLECAINIDE ACETATE Tab 50 mg Tab 100 mg Cap long-acting 100 mg Cap long-acting 200 mg Tambocor Tambocor Tambocor CR Tambocor CR

LAMOTRIGINE LISURIDE HYDROGEN MALEATE PERGOLIDE ROPINIROLE HYDROCHLORIDE TOLCAPONE TOPIRAMATE VIGABATRIN

PROPAFENONE HYDROCHLORIDE SENSORY ORGANS BIMATOPROST HORMONE PREPARATIONS - SYSTEMIC EXCLUDING CONTRACEPTIVE HORMONES DESMOPRESSIN Nasal drops 100 µg per Minirin ml Nasal spray 10 µg per Desmopressin-PH&T dose BRIMONIDINE TARTRATE WITH TIMOLOL MALEATE BRINZOLAMIDE LATANOPROST TRAVOPROST

204

SECTION G: SAFETY CAP MEDICINES

Pharmacists are required, under the Code of Ethics of the Pharmacy Council of New Zealand, to endeavour to use safety caps when dispensing any of the medicines listed in Section G in an oral liquid formulation pursuant to a prescription or Practitioner’s Supply Order. This includes all proprietary and extemporaneously compounded oral liquid preparations of those pharmaceuticals listed in Section G of the Pharmaceutical Schedule. These medicines will be identiﬁed throughout Section B of the Pharmaceutical Schedule with the symbol ‘‡’.

Exemptions

Oral liquid preparations of the pharmaceuticals listed in Section G of the Pharmaceutical Schedule will be dispensed in a container with a safety cap unless: G the practitioner has endorsed the Prescription or Practitioner’s Supply Order, stating that, the Pharmaceutical is not to be dispensed in a container with a safety cap; or G the Contractor has annotated the Prescription or Practitioner’s Supply Order stating that, because of inﬁrmity of the particular person, the Pharmaceutical to be used by that person should not be dispensed in a container with a safety cap; or G the Pharmaceutical is packaged in an Original Pack so designed that on the professional judgement of the Contractor, transfer to a container with a safety cap would be inadvisable or a retrograde procedure.

Reimbursment

Pharmacists will be reimbursed according to their agreement. Where an additional fee is paid on safety caps it will be paid on all dispensings of oral liquid preparations for those pharmaceuticals listed in Section G of the Pharmaceutical Schedule unless the practitioner has endorsed or the contractor has annotated the Prescription or Practitioner’s Supply Order that a safety cap has not been supplied.

Safety Caps (NZS 5825:1991)

20 mm.................................. .Clic-Loc, United Closures & Plastics PLC, England Kerr, Cormack Packaging, Sydney, under licence to Kerr USA 24 mm.................................. .Clic-Loc, United Closures & Plastics PLC, England Clic-Loc, ACI Closures under license to Owens-Illinois Kerr, Cormack Packaging, Sydney, under licence to Kerr USA 28 mm.................................. .Clic-Loc, United Closures & Plastics PLC, England Clic-Loc, ACI Closures under license to Owens-Illinois Kerr, Cormack Packaging, Sydney, under licence to Kerr USA PDL Squeezlok PDL FG

205

SAFETY CAP MEDICINES

ALIMENTARY TRACT AND METABOLISM FERROUS SULPHATE Oral liq 30 mg per 1 ml Ferodan (6 mg elemental per 1 ml) CARDIOVASCULAR SYSTEM AMILORIDE Oral liq 1 mg per ml Biomed CAPTOPRIL Oral liq 5 mg per ml CHLOROTHIAZIDE Oral liq 50 mg per ml DIGOXIN Oral liq 50 µg per ml FUROSEMIDE Oral liq 10 mg per ml SPIRONOLACTONE Oral liq 5 mg per ml Capoten Biomed Lanoxin Lasix Biomed LORMETAZEPAM Tab 1 mg Noctamid (Extemporaneously compounded oral liquid preparations) METHADONE HYDROCHLORIDE Oral liq 2 mg per ml Biodone Oral liq 5 mg per ml Biodone Forte Oral liq 10 mg per ml Biodone Extra Forte MIDAZOLAM Tab 7.5 mg Hypnovel (Extemporaneously compounded oral liquid preparations) MORPHINE HYDROCHLORIDE Oral liq 1 mg per ml RA-Morph Oral liq 2 mg per ml RA-Morph Oral liq 5 mg per ml RA-Morph Oral liq 10 mg per ml RA-Morph NITRAZEPAM Tab 5 mg Nitrados (Extemporaneously compounded oral liquid preparations) OXAZEPAM Tab 10 mg Ox-Pam Tab 15 mg Ox-Pam (Extemporaneously compounded oral liquid preparations) OXYCODONE HYDROCHLORIDE Oral liq 5 mg per 5 ml OxyNorm CLOBAZAM Tab 10 mg Frisium (Extemporaneously compounded oral liquid preparations) CLONAZEPAM Oral drops 2.5 mg per ml

Rivotril

DIAZEPAM Tab 2 mg Arrow-Diazepam Tab 5 mg Arrow-Diazepam (Extemporaneously compounded oral liquid preparations) ETHOSUXIMIDE Oral liq 250 mg per 5 ml

Zarontin

LORAZEPAM Tab 1 mg Ativan Tab 2.5 mg Ativan (Extemporaneously compounded oral liquid preparations)

HORMONE PREPARATIONS - SYSTEMIC EXCLUDING CONTRACEPTIVE HORMONES LEVOTHYROXINE Tab 25 µg Synthroid Tab 50 µg Eltroxin Goldshield Synthroid Tab 100 µg Eltroxin Goldshield Synthroid (Extemporaneously compounded oral liquid preparations) MUSCULOSKELETAL SYSTEM IBUPROFEN Oral liq 100 mg per 5 ml Fenpaed QUININE SULPHATE Tab 200 mg Q 200 Tab 300 mg Q 300 (Extemporaneously compounded oral liquid preparations) NERVOUS SYSTEM ALPRAZOLAM Tab 250 µg Arrow-Alprazolam Tab 500 µg Arrow-Alprazolam Tab 1 mg Arrow-Alprazolam (Extemporaneously compounded oral liquid preparations) CARBAMAZEPINE Oral liq 100 mg per 5 ml

Tegretol

206

SAFETY CAP MEDICINES

PARACETAMOL Oral liq 120 mg per 5 ml Oral liq 250 mg per 5 ml PHENYTOIN SODIUM Oral liq 30 mg per 5 ml SODIUM VALPROATE Oral liq 200 mg per 5 ml PROMETHAZINE HYDROCHLORIDE Oral liq 5 mg per 5 ml Promethazine Elixir SALBUTAMOL Oral liq 2 mg per 5 ml THEOPHYLLINE Oral liq 80 mg per 15 ml

Paracare Junior Ethics Paracetamol Paracare Double Strength Dilantin Epilim S/F Liquid Epilim Syrup

Winthrop

Salapin Nuelin

TEMAZEPAM Tab 10 mg Normison (Extemporaneously compounded oral liquid preparations) TRIAZOLAM Tab 125 µg Hypam Tab 250 µg Hypam (Extemporaneously compounded oral liquid preparations) RESPIRATORY SYSTEM AND ALLERGIES CETIRIZINE HYDROCHLORIDE Oral liq 1 mg per ml Cetirizine - AFT CHLORPHENIRAMINE MALEATE Oral liq 2 mg per 5 ml Histafen DEXTROCHLORPHENIRAMINE MALEATE Oral liq 2 mg per 5 ml Polaramine

TRIMEPRAZINE TARTRATE Oral liq 30 mg per 5 ml Vallergan Forte EXTEMPORANEOUSLY COMPOUNDED PREPARATIONS AND GALENICALS CODEINE PHOSPHATE Powder Douglas (Extemporaneously compounded oral liquid preparations) METHADONE HYDROCHLORIDE Powder AFT (Extemporaneously compounded oral liquid preparations) PHENOBARBITONE SODIUM Powder MidWest (Extemporaneously compounded oral liquid preparations)

207

INDEX Generic Chemicals and Brands

- Symbols 3TC .................................................92 -AA-Lices ............................................62 A-Scabies .......................................62 Abacavir sulphate ...........................91 Abacavir sulphate with lamivudine ................................. 91 Abilify ............................................127 ABM Hydroxocobalamin .................37 Acarbose ........................................31 Accu-Chek Performa ......................32 Accupril ...........................................48 Accuretic 10 ....................................48 Accuretic 20 ....................................48 Acetadote .....................................176 Acetazolamide ..............................168 Acetic acid with 1, 2- propanediol diacetate and benzethonium .......................... 166 Acetic acid with hydroxyquinoline and ricinoleic acid ...................... 69 Acetylcysteine ...............................176 Aci-Jel .............................................69 Aciclovir Infection ......................................88 Sensory ....................................166 Acidex .............................................26 Acipimox .........................................44 Acitretin ...........................................62 Aclasta ..........................................111 Actigall ............................................34 Actrapid ..........................................30 Actrapid Penﬁll ................................30 Acupan .........................................116 Adalat 10 ........................................52 Adalat Oros .....................................52 Adalimumab ....................................98 Adapalene ......................................56 Adeﬁn XL ........................................52 Adefovir dipivoxil .............................86 Adrenaline ......................................54 Advantan ........................................60 AFT-Leﬂunomide ............................98 AFT-Pyrazinamide ..........................85 Agents Affecting the Renin-Angiotensin System .........47 Agents for Parkinsonism and Related Disorders .................... 114 Agents Used in the Treatment of Poisonings ................................. 39 Agrylin ..........................................145 Alanase .........................................164 Albay .............................................159 Albustix ...........................................71 Aldara .............................................64 Alendronate sodium ......................109 Alendronate sodium with cholecalciferol .......................... 109 Alfacalcidol .....................................37 Alginic acid .....................................26 Alitraq ...........................................186 Alkeran .........................................140 Allersoothe ....................................160 Allopurinol .....................................113 Alpha Adrenoceptor Blockers .........47 Alpha-Keri Lotion ............................61 Alphamox ........................................81 Alprazolam ....................................131 Alu-Tab ...........................................26 Aluminium hydroxide ......................26 Amantadine hydrochloride ............114 Ambrisentan ...................................55 Amiloride ........................................53 Amiloride with frusemide ................53 Amiloride with hydrochlorothiazide ................... 53 Aminophylline ...............................164 Amiodarone hydrochloride ..............49 Amirol ...........................................118 Amisulpride ...................................127 Amitrip ..........................................118 Amitriptyline ..................................118 Amlodipine ......................................52 Amorolﬁne ......................................57 Amoxycillin ......................................81 Amoxycillin clavulanate ..................81 Amphotericin B ...............................36 Amsacrine ....................................145 Amsidine .......................................145 Amyl nitrite ......................................54 Anabolic Agents ..............................72 Anaesthetics .................................115 Anagrelide hydrochloride ..............145 Analgesics ....................................116 Anastrozole ...................................154 Androderm ......................................73 Antabuse ......................................138 Antacids and Antiﬂatulants .............26 Anten ............................................119 Anthelmintics ..................................79 Antiacne Preparations ....................56 Antiallergy Preparations ...............159 Antianaemics ..................................40 Antiandrogen Oral Contraceptives ........................... 69 Antiarrhythmics ...............................49 Antibacterials ..................................79 Antibacterials Topical ......................57 Anticholinesterases ........................97 Antidepressants ............................118 Antidiarrhoeals ................................26 Antiepilepsy Drugs .......................121 Antiﬁbrinolytics, Haemostatics and Local Sclerosants ............... 41 Antifungals ......................................84 Antifungals Topical ..........................57 Antihaemorrhoidals .........................28 Antihistamines ..............................159 Antihypotensives .............................50 Antimalarials ...................................85 Antimigraine Preparations ............125 Antinaus ........................................126 Antinausea and Vertigo Agents ..................................... 125 Antipruritic Preparations .................58 Antipsychotics ...............................127 Antiretrovirals ..................................90 Antiretrovirals - Additional Therapies ................................... 92 Antirheumatoid Agents ...................98 Antispasmodics and Other Agents Altering Gut Motility ....................................... 28 Antithrombotic Agents ....................41 Antithymocyte globulin (equine) ................................... 154 Antitrichomonal Agents ..................85 Antituberculotics and Antileprotics ............................... 85 Antiulcerants ...................................28 Antivirals .........................................86 Anxiolytics .....................................131 Anzatax .........................................147 Apidra .............................................30 Apidra SoloStar ..............................30 Apo-Allopurinol .............................113 Apo-Allopurinol S29 ......................113 Apo-Amlodipine ..............................52 Apo-Bromocriptine ........................114 Apo-Cimetidine ...............................28 Apo-Clarithromycin Alimentary ..................................28 Infection ......................................80 Apo-Clomipramine ........................118 Apo-Clopidogrel ..............................41

208

INDEX Generic Chemicals and Brands

Apo-Doxazosin ...............................47 Apo-Folic Acid ................................40 Apo-Gliclazide ................................31 Apo-Megestrol ..............................152 Apo-Moclobemide .........................119 Apo-Nadolol ....................................51 Apo-Nicotinic Acid ..........................45 Apo-Oxybutynin ..............................71 Apo-Pindolol ...................................51 Apo-Prazo .......................................47 Apo-Prednisone ..............................73 Apo-Primidone ..............................123 Apo-Pyridoxine ...............................37 Apo-Risperidone ...........................129 Apo-Selegiline ..............................114 Apo-Selegiline S29 .......................114 Apo-Terbinaﬁne ..............................85 Apo-Thiamine .................................37 Apo-Timol .......................................51 Apo-Timop ....................................167 Apo-Zopiclone ..............................134 Apomine .......................................114 Apomorphine hydrochloride .........114 Aprepitant .....................................125 Apresoline .......................................54 Aquasun 30+ ..................................64 Aqueous cream ..............................61 Aratac .............................................49 Arava ..............................................98 Aremed .........................................154 Arimidex ........................................154 Aripiprazole ...................................127 Aristocort ........................................60 Aromasin ......................................154 Arrow-Alprazolam .........................131 Arrow-Azithromycin ........................80 Arrow-Bendroﬂuazide .....................54 Arrow-Cabergoline ..........................78 Arrow-Calcium ................................38 Arrow-Citalopram ..........................120 Arrow-Diazepam ...........................132 Arrow-Enalapril ...............................47 Arrow-Etidronate ...........................109 Arrow-Lamotrigine ........................123 Arrow-Lisinopril ...............................48 Arrow-Losartan & Hydrochlorothiazide ................... 49 Arrow-Meloxicam ............................98 Arrow-Morphine LA ......................117 Arrow-Nifedipine XR .......................52 Arrow-Norﬂoxacin ...........................95 Arrow-Ornidazole ............................85 Arrow-Ranitidine .............................29 Arrow-Roxithromycin ......................81 Arrow-Sertraline ...........................120 Arrow-Simva 10mg .........................45 Arrow-Simva 20mg .........................45 Arrow-Simva 40mg .........................45 Arrow-Simva 80mg .........................45 Arrow-Sumatriptan ........................125 Arrow-Testosterone ........................73 Arrow-Timolol ...............................167 Arrow-Topiramate .........................124 Arrow-Tramadol ............................116 Arrow-Venlafaxine XR ...................120 Arrowcare .......................................97 Arsenic trioxide .............................145 Arthrexin .........................................98 Asacol .............................................27 Asamax ...........................................27 Ascorbic acid ..................................37 Aspec 300 .....................................116 Aspen Adrenaline ...........................54 Aspen Ceftriaxone ..........................79 Aspirin Blood ..........................................41 Nervous ....................................116 Asthalin .........................................162 Atacand ..........................................48 Atazanavir sulphate ........................92 Atenolol ...........................................50 Atenolol Tablet USP ........................50 ATGAM .........................................154 Ativan ............................................132 Atomoxetine ..................................135 Atorvastatin ....................................45 Atropine sulphate Alimentary ..................................28 Sensory ....................................169 Atropt ............................................169 Atrovent ........................................163 Auranoﬁn ........................................98 Avanza ..........................................120 Avelox .............................................83 Avomine ........................................126 Avonex ..........................................134 Azathioprine .................................154 Azithromycin ...................................80 Azol .................................................78 Azopt ............................................168 AZT .................................................92 -BB-D Micro-Fine ...............................33 B-D Ultra Fine .................................33 B-D Ultra Fine II ..............................33 B-PlexADE ......................................37 Bacillus calmette-guerin (BCG) vaccine .................................... 155 Baclofen ........................................113 Bactroban .......................................57 Bakels Gluten Free Health Bread Mix ........................................... 192 Baraclude .......................................86 Barrier Creams and Emollients .................................. 61 Batrafen ..........................................57 Beclazone 100 ..............................160 Beclazone 250 ..............................160 Beclazone 50 ................................160 Beclomethasone dipropionate ..................... 160, 164 Bee venom allergy treatment ................................. 159 Bendroﬂuazide ................................54 Benhex ...........................................62 Benzathine benzylpenicillin ............81 Benzoin .........................................176 Benztrop .......................................115 Benztropine mesylate ...................115 Benzydamine hydrochloride ...........36 Benzylpenicillin sodium (penicillin G) ............................................... 81 Beta Adrenoceptor Blockers ...........50 Beta Cream ....................................59 Beta Ointment .................................59 Beta Scalp ......................................64 Beta-Adrenoceptor Agonists .........162 Betadine .........................................62 Betadine Skin Prep .........................62 Betaferon ......................................134 Betagan ........................................167 Betahistine dihydrochloride ..........125 Betaloc ............................................51 Betaloc CR .....................................51 Betamethasone dipropionate ..........59 Betamethasone dipropionate with calcipotriol .......................... 63 Betamethasone sodium phosphate with betamethasone acetate ............. 72 Betamethasone valerate ...........59, 64 Betamethasone valerate with clioquinol .................................... 60 Betamethasone valerate with fusidic acid ................................. 60 Betaxolol hydrochloride ................167 Betnovate .......................................59 Betnovate-C ....................................60 Betoptic .........................................167

209

INDEX Generic Chemicals and Brands

Betoptic S .....................................167 Bezaﬁbrate .....................................44 Bezalip Retard ................................44 Bicalaccord ...................................152 Bicalox ..........................................152 Bicalutamide .................................152 Bicillin LA ........................................81 BiCNU ...........................................140 Bimatoprost ..................................168 Biodone ........................................117 Biodone Extra Forte ......................117 Biodone Forte ...............................117 Bisacodyl ........................................35 BK Lotion ........................................61 Bleomycin sulphate ......................145 Blood glucose diagnostic test meter ......................................... 32 Blood glucose diagnostic test strip ............................................ 32 Bonjela ............................................36 Bortezomib ...................................145 Bosentan ........................................55 Breath-Alert ..................................165 Brevinor 1/21 ..................................68 Brevinor 1/28 ..................................68 Brevinor 21 .....................................68 Bricanyl Turbuhaler .......................162 Brimonidine tartrate ......................168 Brimonidine tartrate with timolol maleate .................................... 169 Brinzolamide .................................168 Brolene .........................................166 Bromocriptine mesylate ................114 Brufen .............................................97 Brufen SR .......................................97 Buccastem ....................................126 Budenocort ...................................160 Budesonide Alimentary ..................................26 Respiratory .......................160, 164 Budesonide with eformoterol .............................. 162 Bumetanide ....................................53 Bupropion hydrochloride ...............138 Burinex ...........................................53 Buscopan ........................................28 Buspirone hydrochloride ...............131 Busulphan .....................................140 Butacort Aqueous .........................164 -CCabergoline ....................................78 Cafergot ........................................125 Caffeine citrate .............................165 Cal-d-Forte .....................................37 Calamine ........................................58 Calci-Tab 500 ..................................38 Calci-Tab 600 ..................................38 Calcipotriol ......................................63 Calcitonin ......................................109 Calcitriol ..........................................37 Calcium carbonate ..........................38 Calcium carbonate with aminoacetic acid ........................ 26 Calcium Channel Blockers .............52 Calcium Disodium Versenate .........39 Calcium folinate ............................141 Calcium Folinate Ebewe ...............141 Calcium gluconate ..........................38 Calcium polystyrene sulphonate ................................. 44 Calcium Resonium .........................44 Calogen ........................................182 Calsource .......................................38 Camptosar ....................................144 Candesartan ...................................48 Candestar .......................................48 Canesten ........................................57 Capecitabine .................................141 Capoten ..........................................47 Capsaicin ........................................65 Captopril .........................................47 Carafate ..........................................29 Carbamazepine ............................121 Carbimazole ...................................76 Carboplatin ...................................140 Carboplatin Ebewe .......................140 Carbosorb-X ...................................39 Cardinol ..........................................51 Cardinol LA .....................................51 Cardizem CD ..................................52 CareSens ........................................32 CareSens II .....................................32 CareSens POP ...............................32 Carmustine ...................................140 Carvedilol .......................................50 Catapres .........................................53 Catapres-TTS-1 ..............................53 Catapres-TTS-2 ..............................53 Catapres-TTS-3 ..............................53 CeeNU ..........................................140 Cefaclor monohydrate ....................79 Cefaclor Sandoz .............................79 Cefalexin Sandoz ............................79 Cefazolin sodium ............................79 Cefoxitin sodium .............................79 Ceftriaxone sodium ........................79 Cefuroxime axetil ............................79 Cefuroxime sodium .........................79 Celestone Chronodose ...................72 Celiprolol .........................................50 Cellcept .........................................154 Celol ...............................................50 Centrally Acting Agents ..................53 Cephalexin ABM .............................79 Cephalexin monohydrate ................79 Ceptolate ......................................154 Cerezyme .......................................35 Cetirizine - AFT ............................159 Cetirizine hydrochloride ................159 Cetomacrogol .................................61 Champix .......................................139 Charcoal .........................................39 Chemotherapeutic Agents ............140 Chlorafast .....................................166 Chlorambucil .................................140 Chloramphenicol ...........................166 Chlorhexidine gluconate Alimentary ..................................36 Dermatological ...........................60 Chloroform ....................................176 Chloromycetin ...............................166 Chlorothiazide .................................54 Chlorpheniramine maleate ...........159 Chlorpromazine hydrochloride ........................... 127 Chlorsig ........................................166 Chlorthalidone ................................54 Chlorvescent ..................................44 Cholecalciferol ................................37 Cholestyramine with aspartame ................................. 45 Choline salicylate with cetalkonium chloride .................. 36 Cholvastin .......................................45 Ciclopiroxolamine ...........................57 Cilazapril .........................................47 Cilazapril with hydrochlorothiazide ................... 48 Cilicaine ..........................................82 Cilicaine VK ....................................82 Ciloxan ..........................................166 Cimetidine .......................................28 Cipﬂox .............................................82 Ciproﬂoxacin Infection ......................................82 Sensory ....................................166 Cisplatin ........................................140 Cisplatin Ebewe ............................140 Citalopram hydrobromide .............120

210

INDEX Generic Chemicals and Brands

Cladribine .....................................142 Clarithromycin Alimentary ..................................28 Infection ......................................80 Clexane ..........................................41 Climara 100 ....................................74 Climara 50 ......................................74 Clindamycin ....................................83 Clobazam .....................................121 Clobetasol propionate ...............59, 64 Clobetasone butyrate .....................59 Clomazol Dermatological ...........................57 Genito-Urinary ............................69 Clomiphene citrate ..........................78 Clomipramine hydrochloride .........118 Clonazepam .................................121 Clonidine .........................................53 Clonidine hydrochloride Cardiovascular ...........................53 Nervous ....................................125 Clopidogrel .....................................41 Clopine .........................................127 Clopixol .................................129, 131 Clotrimazole Dermatological ...........................57 Genito-Urinary ............................69 Clozapine ......................................127 Clozaril .........................................127 Co-Renitec ......................................48 Co-trimoxazole ...............................83 Coal tar ...........................................63 Coal tar with allantoin, menthol, phenol and sulphur .................... 63 Coal tar with salicylic acid and sulphur ....................................... 63 Coco-Scalp .....................................63 Codeine phosphate Extemporaneous ......................176 Nervous ....................................116 Cogentin .......................................115 Colaspase (L-asparaginase) .........146 Colchicine .....................................113 Colestid ...........................................45 Colestipol hydrochloride .................45 Colgout .........................................113 Colifoam .........................................27 Colistin sulphomethate ...................83 Colistin-Link ....................................83 Collodion ﬂexible ..........................176 Colofac ...........................................28 Coloxyl ......................................34, 35 Combigan .....................................169 Combivir .........................................92 Compound electrolytes ...................44 Compound hydroxybenzoate ..................... 176 Comtan .........................................114 Concerta .......................................137 Condoms ........................................66 Condyline ........................................65 Contraceptives - Hormonal .............67 Contraceptives Non-hormonal ............................ 66 Copaxone .....................................134 Corangin .........................................54 Cordarone-X ...................................49 Corticosteroids and Related Agents for Systemic Use ........... 72 Corticosteroids Topical ...................59 Cosmegen ....................................146 Cosopt ..........................................168 Coumadin .......................................43 Coversyl ..........................................48 Cozaar ............................................49 Creon 10000 ...................................34 Creon Forte ....................................34 Crixivan ...........................................92 Crotamiton ......................................58 Crystacide ......................................57 Curam .............................................81 Cyclizine hydrochloride .................125 Cyclizine lactate ............................125 Cycloblastin ..................................140 Cyclogyl ........................................169 Cyclopentolate hydrochloride ........................... 169 Cyclophosphamide .......................140 Cyclosporin ...................................157 Cyklokapron ....................................41 Cyproterone acetate .......................73 Cyproterone acetate with ethinyloestradiol ......................... 69 Cytarabine ....................................142 Cytotec ...........................................28 Cytoxan ........................................140 -DD-Penamine ....................................98 d4T .................................................92 Dabigatran ......................................42 Dacarbazine .................................146 Daclin ..............................................98 Dactinomycin (actinomycin D) ............................................. 146 Daivobet .........................................63 Daivonex .........................................63 Daktarin Alimentary ..................................36 Dermatological ...........................58 Dalacin C ........................................83 Danazol ..........................................78 Danthron with poloxamer ................35 Dantrium .......................................113 Dantrolene sodium .......................113 Daonil .............................................31 Dapa-Tabs ......................................54 Dapsone .........................................85 Darunavir ........................................92 Dasatinib .......................................149 Daunorubicin ................................146 DBL Aminophylline .......................164 DBL Bleomycin Sulfate .................145 DBL Doxorubicin ...........................146 DBL Ergometrine ............................70 DBL Leucovorin Calcium ..............141 DBL Methotrexate .........................144 DBL Morphine Sulphate ...............117 DBL Pethidine Hydrochloride .......................... 118 DBL Tobramycin .............................84 DDI .................................................91 De-Worm ........................................79 Deca-Durabolin Orgaject ................72 Deferiprone .....................................46 Depo-Medrol ...................................72 Depo-Medrol with Lidocaine ...........72 Depo-Provera .................................69 Depo-Testosterone .........................73 Deprim ............................................83 Dermol ......................................59, 64 Desferrioxamine mesylate ..............46 Desmopressin .................................77 Desmopressin-PH&T ......................77 Detection of Substances in Urine .......................................... 71 Dexamethasone Hormone ....................................72 Sensory ....................................167 Dexamethasone sodium phosphate .................................. 72 Dexamethasone with framycetin and gramicidin ......................... 166 Dexamethasone with neomycin and polymyxin b sulphate .........167 Dexamphetamine sulphate ...........135 Dextrochlorpheniramine maleate .................................... 159 Dextrose .........................................43 Dextrose with electrolytes ...............44

211

INDEX Generic Chemicals and Brands

DHC Continus ...............................116 Diabetes .........................................29 Diabetes Management ...................31 Diamide Relief ................................26 Diamox .........................................168 Diaphragm ......................................66 Diasip ............................................183 Diason RTH ..................................183 Diastop ...........................................26 Diazepam .............................121, 132 Dibenyline .......................................47 Diclax SR ........................................97 Diclofenac Sandoz ..........................97 Diclofenac sodium Musculoskeletal System .............97 Sensory ....................................167 Didanosine [DDI] ............................91 Differin ............................................56 Difﬂam ............................................36 Diﬂucan ...........................................84 Diﬂucortolone valerate ....................59 Digestives Including Enzymes .................................... 34 Digoxin ............................................50 Dihydrocodeine tartrate ................116 Dilantin ..........................................123 Dilantin Infatab ..............................123 Dilatrend .........................................50 Diltiazem hydrochloride ..................52 Dilzem .............................................52 Dimetriose ......................................78 Dipentum ........................................27 Diphenoxylate hydrochloride with atropine sulphate ....................... 26 Diprosone .......................................59 Diprosone OV .................................59 Dipyridamole ...................................41 Disinfecting and Cleansing Agents ....................................... 60 Disipal ...........................................115 Disopyramide phosphate ................50 Disulﬁram ......................................138 Diuretics ..........................................53 Diurin 40 .........................................53 Dixarit ...........................................125 DM Ject ..........................................33 Docetaxel ......................................146 Docetaxel Ebewe ..........................146 Docusate sodium ............................34 Docusate sodium with sennosides ................................ 34 Domperidone ................................125 Donepezil hydrochloride ...............138 Donepezil-Rex ..............................138 Dopergin .......................................114 Dopress ........................................118 Dornase alfa .................................164 Dorzolamide hydrochloride ...........168 Dorzolamide hydrochloride with timolol maleate ........................ 168 Dostinex ..........................................78 Dothiepin hydrochloride ................118 Doxazosin mesylate .......................47 Doxepin hydrochloride ..................119 Doxine ............................................82 Doxorubicin ...................................146 Doxorubicin Ebewe .......................146 Doxy-50 ..........................................82 Doxycycline hydrochloride ..............82 DP Lotion ........................................61 DP Lotn HC ....................................59 DP-Anastrozole ............................154 Dr Reddy’s Olanzapine .........128, 131 Dr Reddy’s Omeprazole .................29 Dr Reddy’s Ondansetron ..............126 Dr Reddy’s Pantoprazole ................29 Dr Reddy’s Quetiapine .................128 Dr Reddy’s Risperidone ................129 Dr Reddy’s Terbinaﬁne ...................85 Drugs Affecting Bone Metabolism .............................. 108 Dulcolax ..........................................35 Duocal Super Soluble Powder ..................................... 181 Duolin ...........................................163 Duolin HFA ...................................163 Durex Conﬁdence ...........................66 Durex Extra Safe ............................66 Durex Select Flavours ....................66 Duride .............................................54 Dynacirc-SRO .................................52 -EE-Mycin ...........................................81 Ear Preparations ...........................166 Ear/Eye Preparations ...................166 Easiphen .......................................194 Easiphen Liquid ............................194 Econazole nitrate ............................58 Efavirenz .........................................91 Efexor XR .....................................120 Eformoterol fumarate ....................161 Efudix ..............................................65 Egopsoryl TA ..................................63 Elecare .........................................195 Elecare LCP .................................195 Electral ............................................44 Elemental 028 Extra .....................186 Eligard ............................................77 Elocon .............................................60 Eloxatin .........................................140 Eltroxin ............................................76 Emend Tri-Pack ............................125 EMLA ............................................115 Emtricitabine ...................................91 Emtriva ...........................................91 Emulsifying ointment ......................61 Enalapril .........................................47 Enalapril with hydrochlorothiazide ................... 48 Enbrel ...........................................103 Endocrine Therapy .......................152 Endoxan .......................................140 Enfuvirtide ......................................92 Enoxaparin sodium .........................41 Ensure ..........................................190 Ensure Plus ..................................190 Ensure Plus HN ............................189 Ensure Plus RTH ..........................189 Entacapone ..................................114 Entecavir .........................................86 Entocort CIR ...................................26 Enuclene .......................................169 Epilim ............................................124 Epilim Crushable ..........................124 Epilim IV .......................................124 Epilim S/F Liquid ...........................124 Epilim Syrup .................................124 Epirubicin ......................................146 Epirubicin Ebewe ..........................146 Eprex ..............................................40 ERA ................................................81 Ergometrine maleate ......................70 Ergotamine tartrate with caffeine .................................... 125 Erlotinib hydrochloride ..................150 Erythrocin IV ...................................81 Erythromycin ethyl succinate ..........81 Erythromycin lactobionate ..............81 Erythromycin stearate ....................81 Erythropoietin alpha .......................40 Erythropoietin beta .........................40 Escitalopram .................................120 Estraderm TTS 100 ........................74 Estraderm TTS 25 ..........................74 Estraderm TTS 50 ..........................74 Estradot ..........................................74 Estrofem .........................................74 Etanercept ....................................103 Ethambutol hydrochloride ...............85

212

INDEX Generic Chemicals and Brands

Ethics Aspirin ................................116 Ethics Aspirin EC ............................41 Ethics Ibuprofen ..............................97 Ethics Paracetamol .......................116 Ethinyloestradiol .............................75 Ethinyloestradiol with desogestrel ................................ 67 Ethinyloestradiol with levonorgestrel ............................ 68 Ethinyloestradiol with norethisterone ............................ 68 Ethosuximide ................................122 Etidronate disodium ......................109 Etopophos ....................................147 Etoposide ......................................147 Etoposide phosphate ....................147 Etravirine ........................................91 Eumovate .......................................59 Evista ............................................109 Exemestane ..................................154 Extemporaneously Compounded Preparations and Galenicals ................................ 176 Eye Preparations ..........................166 EZ-ﬁt Paediatric Mask ..................165 Ezetimibe ........................................45 Ezetimibe with simvastatin .............46 Ezetrol ............................................45 -FFamotidine ......................................28 Famox .............................................28 Felo 10 ER ......................................52 Felo 5 ER ........................................52 Felodipine .......................................52 Femtran 100 ...................................74 Femtran 50 .....................................74 Fenpaed .........................................97 Fentanyl ........................................116 Fentanyl citrate .............................117 Ferodan ..........................................38 Ferriprox .........................................46 Ferro-F-Tabs ...................................38 Ferro-tab .........................................38 Ferrograd ........................................38 Ferrograd-Folic ...............................39 Ferrous fumarate ............................38 Ferrous fumarate with folic acid ............................................ 38 Ferrous sulphate .............................38 Ferrous sulphate with folic acid ............................................ 39 Ferrum H ........................................39 Fexofenadine hydrochloride .........159 Fibalip .............................................44 Fibro-vein ........................................41 Finasteride ......................................70 Fine Ject .........................................33 Fintral ..............................................70 Flagyl ..............................................85 Flagyl-S ..........................................85 Flamazine .......................................57 Flecainide acetate ..........................50 Fleet Phosphate Enema .................35 Flixonase Hayfever & Allergy ...................................... 164 Flixotide ........................................160 Flixotide Accuhaler .......................160 Florinef ...........................................72 Fluanxol ........................................129 Fluarix .............................................96 Flucloxacillin sodium .......................82 Flucloxin .........................................82 Fluconazole ....................................84 Fludara .........................................142 Fludara Oral ..................................142 Fludarabine Ebewe .......................142 Fludarabine phosphate .................142 Fludrocortisone acetate ..................72 Fluids and Electrolytes ...................43 Flumetasone pivalate ...................166 Fluocortolone caproate with ﬂuocortolone pivalate and cinchocaine ................................ 28 Fluorometholone ...........................167 Fluorouracil Ebewe .......................142 Fluorouracil sodium Dermatological ...........................65 Oncology ..................................142 Fluox .............................................120 Fluoxetine hydrochloride ...............120 Flupenthixol decanoate ................129 Fluphenazine decanoate ..............130 Flutamide ......................................152 Flutamin ........................................152 Fluticasone ...................................160 Fluticasone propionate .................164 Fluticasone with salmeterol ..........162 Fluvax .............................................96 FML ..............................................167 Foban .............................................57 Folic acid ........................................40 Food Thickeners ...........................192 Foods And Supplements For Inborn Errors Of Metabolism .............................. 193 Foradil ...........................................161 Forteo ...........................................110 Fortimel Regular ...........................184 Fortini ...........................................185 Fortini Multi Fibre ..........................185 Fortisip ..........................................190 Fortisip Multi Fibre ........................191 Fosamax .......................................109 Fosamax Plus ...............................109 Framycetin sulphate .....................166 FreeStyle Lite .................................32 Frisium ..........................................121 Frumil ..............................................53 Frusemide-Claris ............................53 Fucicort ...........................................60 Fucidin ............................................83 Fucithalmic ...................................166 Fungilin ...........................................36 Furosemide .....................................53 Fusidic acid Dermatological ...........................57 Infection ......................................83 Sensory ....................................166 Fuzeon ............................................92 -GGabapentin ...................................122 Gabapentin (Neurontin) ................122 Gamma benzene hexachloride .............................. 62 Gastrosoothe ..................................28 Gaviscon Double Strength ..............26 Gaviscon Infant ...............................26 Gemcitabine Ebewe .....................143 Gemcitabine hydrochloride ...........143 Gemﬁbrozil .....................................44 Gemzar .........................................143 Generaid Plus ...............................184 Genoptic .......................................166 Genotropin ......................................77 Genox ...........................................153 Gentamicin sulphate Infection ......................................83 Sensory ....................................166 Gestrinone ......................................78 Ginet 84 ..........................................69 Glatiramer acetate ........................134 Glibenclamide .................................31 Gliclazide ........................................31 Glipizide ..........................................31 Glivec ............................................150 Glucagen Hypokit ...........................29 Glucagon hydrochloride ..................29 Glucerna Select ............................183 Glucerna Select RTH ....................183

213

INDEX Generic Chemicals and Brands

Glucobay ........................................31 Gluten Free Foods ........................192 Glycerin with sodium saccharin ................................. 176 Glycerin with sucrose ...................176 Glycerol Alimentary ..................................35 Extemporaneous ......................176 Glyceryl trinitrate ............................54 Gold Knight .....................................66 Gopten ............................................48 Goserelin acetate ...........................77 Gutron .............................................50 Gynaecological Anti-infectives ............................ 69 -HHabitrol .........................................139 Haldol ...........................................130 Haldol Concentrate .......................130 Haloperidol ...................................128 Haloperidol decanoate .................130 Hamilton Sunscreen .......................64 healthE Fatty Cream .......................61 Healtheries Simple Baking Mix ........................................... 192 Hemastix .........................................71 Heparin sodium ..............................42 Heparinised saline ..........................42 Hepsera ..........................................86 Herceptin ......................................156 Hexamine hippurate .......................95 Hiprex .............................................95 Histafen ........................................159 Holoxan ........................................140 Homatropine hydrobromide ..........169 Horleys Bread Mix ........................192 Horleys Flour ................................192 Hormone Replacement Therapy Systemic .................................... 73 Humalog .........................................31 Humalog Mix 25 ..............................30 Humalog Mix 50 ..............................30 Humira ............................................98 HumiraPen ......................................98 Humulin 30/70 ................................30 Humulin NPH ..................................30 Humulin R .......................................30 Hybloc .............................................51 Hydralazine .....................................54 Hydrea ..........................................147 Hydrocortisone Dermatological ...........................59 Hormone ....................................72 Hydrocortisone acetate ..................27 Hydrocortisone butyrate ...........59, 64 Hydrocortisone with cinchocaine ................................ 28 Hydrocortisone with miconazole ................................ 60 Hydrocortisone with natamycin and neomycin ............................ 60 Hydrocortisone with wool fat and mineral oil .................................. 59 Hydroderm Lotion ...........................61 Hydrogen peroxide Alimentary ..................................36 Dermatological ...........................57 Hydroxocobalamin ..........................37 Hydroxychloroquine sulphate .........85 Hydroxyurea .................................147 Hygroton .........................................54 Hyoscine (scopolamine) ...............125 Hyoscine hydrobromide ................126 Hyoscine N-butylbromide ...............28 Hypam ..........................................134 Hyperuricaemia and Antigout ................................... 113 Hypnovel .......................................134 Hypromellose ................................169 Hysite ............................................168 Hyzaar ............................................49 -IIbiamox ...........................................81 Ibuprofen ........................................97 Idarubicin hydrochloride ...............147 Ifosfamide .....................................140 Iloprost ............................................55 Imatinib mesylate ..........................150 Imiglucerase ...................................35 Imipramine hydrochloride .............119 Imiquimod .......................................64 Immune Modulators ........................93 Immunosuppressants ...................154 Imuprine .......................................154 Imuran ..........................................154 Indapamide .....................................54 Indinavir ..........................................92 Indomethacin ..................................98 Infant Formulae ............................194 Inﬂuenza vaccine ............................96 Inhaled Anticholinergic Agents ..................................... 163 Inhaled Corticosteroids .................160 Inhaled Long-acting Beta-adrenoceptor Agonists ................................... 160 Inhibace Plus ..................................48 Innovacon hCG One Step Pregnancy Test .......................... 70 Insulin aspart ..................................30 Insulin glargine ...............................30 Insulin glulisine ...............................30 Insulin isophane ..............................30 Insulin isophane with insulin neutral ........................................ 30 Insulin lispro ....................................31 Insulin lispro with insulin lispro protamine ................................... 30 Insulin neutral .................................30 Insulin pen needles .........................33 Insulin syringes, disposable with attached needle ......................... 33 Intal Spincaps ...............................163 Intelence .........................................91 Interferon alpha-2a .........................94 Interferon alpha-2b .........................94 Interferon beta-1-alpha .................134 Interferon beta-1-beta ...................134 Intra-uterine device .........................66 Intron-A ...........................................94 Ipratropium bromide .............163–164 Irinotecan ......................................144 Irinotecan-Rex ..............................144 Iron Overload ..................................46 Iron polymaltose .............................39 Isentress .........................................92 Ismo 20 ...........................................54 Isoniazid .........................................85 Isoprenaline hydrochloride .............54 Isoptin .............................................53 Isopto Carpine ..............................169 Isopto Homatropine ......................169 Isosorbide mononitrate ...................54 Isosource Standard ......................189 Isosource Standard RTH ..............189 Isotretinoin ......................................56 Isradipine ........................................52 Isuprel .............................................54 Itch-Soothe .....................................58 Itraconazole ....................................84 Itrazole ............................................84 -JJadelle ............................................69 Jevity ............................................189 Jevity RTH ....................................189 -KKaletra ............................................92

214

INDEX Generic Chemicals and Brands

Karicare Food Thickener ..............192 Kemadrin ......................................115 Kenacomb ....................................166 Kenacort-A ......................................73 Kenacort-A40 ..................................73 Ketoconazole Dermatological ...........................64 Infection ......................................84 Ketone blood beta-ketone electrodes .................................. 31 Ketoprofen ......................................97 Ketostix ...........................................31 Kindergen .....................................184 Kivexa .............................................91 Klacid ..............................................80 Klamycin Alimentary ..................................28 Infection ......................................80 Kliogest ...........................................75 Kliovance ........................................75 Konakion MM ..................................41 Konsyl-D .........................................34 -LLabetalol .........................................51 Lacosamide ..................................122 Lacri-Lube ....................................170 Lactulose ........................................35 Laevolac .........................................35 Lamictal ........................................123 Lamivudine ...............................87, 92 Lamotrigine ...................................123 Lanoxin ...........................................50 Lanoxin PG .....................................50 Lansoprazole ..................................29 Lantus .............................................30 Lantus SoloStar ..............................30 Lanvis ...........................................144 Lanzol Relief ...................................29 Largactil ........................................127 Lasix ...............................................53 Latanoprost ...................................168 Lax-Tab ...........................................35 Laxatives ........................................34 Laxofast 120 ...................................34 Laxofast 50 .....................................34 Laxsol .............................................34 Leﬂunomide ....................................98 Letara ...........................................154 Letrozole .......................................154 Leukeran FC .................................140 Leunase ........................................146 Leuprorelin ......................................77 Leustatin .......................................142 Levetiracetam ...............................123 Levetiracetam-Rex ........................123 Levlen ED .......................................68 Levobunolol ..................................167 Levocabastine ..............................167 Levodopa with benserazide ..........114 Levodopa with carbidopa ..............114 Levomepromazine ........................128 Levonorgestrel Genito-Urinary ............................69 Hormone ....................................75 Levothyroxine ..................................76 Lifestyles Flared .............................66 Lignocaine ....................................115 Lignocaine hydrochloride ..............115 Lignocaine with chlorhexidine ........................... 115 Lignocaine with prilocaine ............115 Lincocin ..........................................83 Lincomycin ......................................83 Lipazil .............................................44 Lipid Modifying Agents ...................44 Lipitor ..............................................45 Liquigen ........................................182 Lisinopril .........................................48 Lisuride hydrogen maleate ...........114 Litak ..............................................142 Lithicarb ........................................128 Lithium carbonate .........................128 Livostin .........................................167 Locacorten-Viaform ED’s ..............166 Locasol .........................................195 Loceryl ............................................57 Locoid .......................................59, 64 Locoid Crelo ...................................59 Locoid Lipocream ...........................59 Locorten-Vioform ..........................166 Lodoxamide trometamol ...............167 Loette .............................................68 Logem ...........................................123 Lomide ..........................................167 Lomustine .....................................140 Loperamide hydrochloride ..............26 Lopinavir with ritonavir ....................92 Lopresor .........................................51 Loproﬁn .........................................194 Loproﬁn Mix ..................................194 Loraclear Hayfever Relief .............160 Lorapaed ......................................160 Loratadine .....................................160 Lorazepam ....................................132 Lormetazepam .............................134 Losartan .........................................49 Lostaar ............................................49 Lovir ................................................88 Loxalate ........................................120 Loxamine ......................................120 Lucrin Depot ...................................77 Lucrin Depot PDS ...........................77 Ludiomil ........................................119 Lumigan ........................................168 Lycinate ..........................................54 Lyderm ............................................62 -Mm-Captopril .....................................47 m-Eslon ........................................117 m-Mometasone ...............................60 Mabthera ......................................155 Macrogol 3350 ................................35 Madopar 125 ................................114 Madopar 250 ................................114 Madopar 62.5 ...............................114 Madopar Dispersible .....................114 Madopar HBS ...............................114 Magnesium hydroxide ...................176 Magnesium sulphate Alimentary ..................................39 Dermatological ...........................65 Malathion ........................................62 Maprotiline hydrochloride .............119 Marevan ..........................................43 Marine Blue Lotion SPF 30+ ..........64 Marquis Black .................................66 Marquis Conforma ..........................66 Marquis Protecta ............................66 Marquis Selecta ..............................66 Marquis Sensolite ...........................66 Marquis Supalite .............................66 Marquis Titillata ..............................66 MarquisTantiliza ..............................66 Martindale Acetylcysteine .............176 Marvelon 21 ....................................67 Marvelon 28 ....................................67 Mask for spacer device .................165 Mast Cell Stabilisers .....................163 Maxalt Melt ...................................125 Maxidex ........................................167 Maxitrol .........................................167 MCT oil (Nutricia) .........................182 Mebendazole ..................................79 Mebeverine hydrochloride ..............28 Medrol .............................................72 Medroxyprogesterone acetate Genito-Urinary ............................69 Hormone ..............................75–76 Mefenamic acid ..............................97

215

INDEX Generic Chemicals and Brands

Megace .........................................152 Megestrol acetate .........................152 Meloxicam ......................................98 Melphalan .....................................140 Menthol ...........................................58 Mercaptopurine ............................144 Mercilon 21 .....................................67 Mercilon 28 .....................................67 Mesalazine .....................................27 Mesna ...........................................147 Mestinon .........................................97 Metabolic Disorder Agents .............35 Metabolic Mineral Mixture .............194 Metamide ......................................126 Metformin hydrochloride .................31 Methadone hydrochloride Extemporaneous ......................176 Nervous ....................................117 Methatabs .....................................117 Methoblastin .................................144 Methopt .........................................169 Methotrexate .................................144 Methotrexate Ebewe .....................144 Methyl hydroxybenzoate ...............177 Methylcellulose .............................177 Methylcellulose with glycerin and sodium saccharin .................... 177 Methylcellulose with glycerin and sucrose .................................... 177 Methyldopa .....................................53 Methylphenidate hydrochloride ........................... 136 Methylphenidate hydrochloride extended-release ..................... 137 Methylprednisolone ........................72 Methylprednisolone aceponate .................................. 60 Methylprednisolone acetate ............72 Methylprednisolone acetate with lignocaine .................................. 72 Methylprednisolone sodium succinate ................................... 72 Methylxanthines ............................164 Metoclopramide hydrochloride ........................... 126 Metoclopramide hydrochloride with paracetamol ..................... 125 Metopirone ......................................78 Metoprolol - AFT CR .......................51 Metoprolol succinate .......................51 Metoprolol tartrate ..........................51 Metronidazole .................................85 Metyrapone .....................................78 Miacalcic .......................................109 Mianserin hydrochloride ...............119 Micolette .........................................35 Miconazole .....................................36 Miconazole nitrate Dermatological ...........................58 Genito-Urinary ............................70 Micreme ..........................................70 Micreme H ......................................60 Microgynon 20 ED ..........................68 Microgynon 30 ................................68 Microgynon 30 ED ..........................68 Microgynon 50 ED ..........................68 Microlut ...........................................69 Midazolam ....................................134 Midodrine ........................................50 Minaphlex .....................................194 Minerals ..........................................38 Minidiab ..........................................31 Minirin .............................................77 Mino-tabs ........................................82 Minocycline hydrochloride ..............82 Minomycin ......................................82 Minor Skin Infections ......................62 Mirena .............................................75 Mirtazapine ...................................120 Misoprostol .....................................28 Mitomycin C ..................................147 Mitozantrone .................................147 Mitozantrone Ebewe .....................147 Mixtard 30 .......................................30 Moclobemide ................................119 Modaﬁnil .......................................137 Modavigil ......................................137 Modecate ......................................130 Moducal ........................................180 Moduretic ........................................53 Mogine ..........................................123 Mometasone furoate .......................60 Monofeme .......................................68 Monogen .......................................183 Morphine hydrochloride ................117 Morphine sulphate ........................117 Morphine tartrate ..........................117 Morrex Maltodextrin ......................180 Motilium ........................................125 Mouth and Throat ...........................36 Movicol ...........................................35 Moxiﬂoxacin ....................................83 MSUD Maxamaid .........................193 MSUD Maxamum .........................193 Mucilaginous laxatives ....................34 Mucilaginous laxatives with stimulants .................................. 34 Mucilax ...........................................34 Mucolytics .....................................164 MultiADE .........................................38 Multiload Cu 375 .............................66 Multiload Cu 375 SL .......................66 Multiple Sclerosis Treatments ............................... 132 Multivitamins ...................................37 Mupirocin ........................................57 Muscle Relaxants .........................113 Myaccord ......................................154 Myambutol ......................................85 Mycobutin .......................................85 Mycophenolate mofetil ..................154 Mycostatin ......................................58 Mydriacyl ......................................169 Mylan Fentanyl Patch ...................116 Mylanta P ........................................26 Myleran .........................................140 Myloc CR ........................................51 Myocrisin ........................................98 Myometrial and Vaginal Hormone Preparations .............................. 70 -NNadolol ...........................................51 Nalcrom ..........................................27 Naloxone hydrochloride ................138 Naltraccord ...................................138 Naltrexone hydrochloride ..............138 Nandrolone decanoate ...................72 Naphazoline hydrochloride ...........170 Naphcon Forte ..............................170 Naprosyn SR 1000 .........................97 Naprosyn SR 750 ...........................97 Naproxen ........................................97 Nardil ............................................119 Nasal Preparations .......................164 Natulan .........................................147 Nausicalm .....................................125 Navelbine ......................................148 Navoban .......................................126 Nedocromil ...................................163 Nefopam hydrochloride ................116 Neo-Mercazole ...............................76 Neocate ........................................195 Neocate Advance .........................195 Neocate LCP ................................195 Neoral ...........................................157 NeoRecormon ................................40 Neostigmine ....................................97 Neotigason .....................................62

216

INDEX Generic Chemicals and Brands

Nepro (strawberry) ........................186 Nepro (vanilla) ..............................186 Nerisone .........................................59 Neulactil ........................................128 NeuroKare ......................................38 Neurontin ......................................122 Nevirapine ......................................91 Nicotine .........................................139 Nicotinic acid ..................................45 Nifedipine ........................................52 Nifuran ............................................95 Nilstat Alimentary ..................................36 Genito-Urinary ............................70 Infection ......................................84 Nipent ...........................................147 Nitrados ........................................134 Nitrates ...........................................54 Nitrazepam ...................................134 Nitroderm TTS ................................54 Nitrofurantoin ..................................95 Nitrolingual Pumpspray ..................54 Nizoral ............................................84 Noctamid ......................................134 Nodia ..............................................26 Noﬂam 250 .....................................97 Noﬂam 500 .....................................97 Non-steroidal Anti-inﬂammatory Drugs (NSAIDs) ......................... 97 Nordette 28 .....................................68 Norethisterone Genito-Urinary ............................69 Hormone ....................................76 Norethisterone with mestranol ................................... 68 Norﬂex ..........................................113 Norﬂoxacin ......................................95 Noriday 28 ......................................69 Norimin ...........................................68 Norinyl-1/28 ....................................68 Normacol Plus ................................34 Normison ......................................134 Norpress .......................................119 Nortriptyline hydrochloride ............119 Norvir ..............................................92 NovaSource Renal .......................186 Novatretin .......................................62 NovoFine ........................................33 NovoRapid ......................................30 NovoRapid Penﬁll ...........................30 Nozinan ........................................128 Nuelin ...........................................164 Nuelin-SR .....................................164 Nupentin .......................................122 Nutraplus ........................................61 Nutrient Modules ..........................180 Nutrini Energy RTH ......................185 Nutrini RTH ...................................185 NutriniDrink ...................................185 NutriniDrink Multiﬁbre ...................185 Nutrison Concentrated .................186 Nutrison Energy Multi Fibre ..........189 Nutrison Multi Fibre ......................189 Nutrison Standard RTH ................189 Nyefax Retard .................................52 Nystatin Alimentary ..................................36 Dermatological ...........................58 Genito-Urinary ............................70 Infection ......................................84 NZB Low Gluten Bread Mix ..........192 -OOctreotide (somatostatin analogue) ................................. 152 Oestradiol .......................................74 Oestradiol valerate .........................74 Oestradiol with norethisterone ............................ 75 Oestriol Genito-Urinary ............................70 Hormone ....................................75 Oestrogens .....................................75 Oestrogens with medroxyprogesterone ................ 75 Oil in water emulsion ......................61 Olanzapine ...........................128, 131 Olanzapine pamoate monohydrate ............................ 130 Olanzine .......................................128 Olanzine-D ....................................131 Olbetam ..........................................44 Olsalazine .......................................27 Omeprazole ....................................29 Omezol Relief .................................29 On Call Advanced ...........................32 OncoTICE .....................................155 Ondansetron .................................126 One-Alpha ......................................37 Onkotrone .....................................147 Optium 5 second test ......................32 Optium Blood Ketone Test Strips ......................................... 31 Optium Xceed .................................32 Ora-Blend .....................................177 Ora-Blend SF ................................177 Ora-Plus .......................................177 Ora-Sweet ....................................176 Ora-Sweet SF ...............................176 Orabase ..........................................36 Oracort ...........................................36 Oral Supplements/Complete Diet (Nasogastric/Gastrostomy Tube Feed) .............................. 182 Oratane ...........................................56 Orgran ..........................................193 Ornidazole ......................................85 Orphenadrine citrate .....................113 Orphenadrine hydrochloride .........115 Ortho All-ﬂex ...................................66 Ortho-tolidine ..................................71 Oruvail SR ......................................97 Osmolite .......................................189 Osmolite RTH ...............................189 Ospamox ........................................81 Ospamox Paediatric Drops .............81 Other Endocrine Agents .................78 Other Oestrogen Preparations .............................. 75 Other Progestogen Preparations .............................. 75 Other Skin Preparations .................65 Ovestin Genito-Urinary ............................70 Hormone ....................................75 Ox-Pam ........................................132 Oxaliplatin .....................................140 Oxaliplatin Ebewe .........................140 Oxazepam ....................................132 Oxis Turbuhaler ............................161 Oxybutynin ......................................71 Oxycodone hydrochloride .............118 OxyContin .....................................118 OxyNorm ......................................118 Oxypentifylline ................................54 Oxytocin ..........................................70 Ozole ..............................................84 -PPacifen ..........................................113 Paciﬁc Atenolol ...............................50 Paciﬁc Buspirone ..........................131 Paclitaxel ......................................147 Paclitaxel Actavis ..........................147 Paclitaxel Ebewe ..........................147 Paediatric Seravit ...........................37 Pamidronate disodium ..................109 Pamisol .........................................109 Panadol ........................................116 Pancreatic enzyme .........................34 Pantocid IV .....................................29

217

INDEX Generic Chemicals and Brands

Pantoprazole ...................................29 Panzytrat ........................................34 Papaverine hydrochloride ...............54 Paracare .......................................116 Paracare Double Strength ............116 Paracare Junior ............................116 Paracetamol .................................116 Paracetamol + Codeine (Relieve) .................................. 118 Paracetamol with codeine ............118 ParaCode .....................................118 Parafast ........................................116 Parafﬁn ...........................................62 Parafﬁn liquid with soft white parafﬁn ..................................... 170 Parafﬁn liquid with wool fat liquid ........................................ 170 Paraldehyde ..................................121 Paramax .......................................125 Parasiticidal Preparations ...............62 Parnate .........................................119 Paroxetine hydrochloride ..............120 Paxam ..........................................121 Peak ﬂow meter ............................165 Pedialyte - Bubblegum ....................44 Pedialyte - Fruit ...............................44 Pedialyte - Plain ..............................44 Pediasure .....................................185 Pediasure RTH .............................185 Pegasys ..........................................94 Pegasys RBV Combination Pack ........................................... 94 Pegylated interferon alpha-2a .........94 Penicillamine ..................................98 PenMix 30 .......................................30 PenMix 40 .......................................30 PenMix 50 .......................................30 Pentasa ..........................................27 Pentostatin (deoxycoformycin) ................... 147 Pepti Junior Gold ..........................196 Peptisoothe .....................................29 Peptisorb ......................................187 Pergolide ......................................114 Perhexiline maleate ........................52 Pericyazine ...................................128 Perindopril ......................................48 Permax .........................................114 Permethrin ......................................62 Persantin ........................................41 Pethidine hydrochloride ................118 Pevaryl ............................................58 Pexsig .............................................52 Pharmacare ..................................116 Phenelzine sulphate .....................119 Phenobarbitone ............................123 Phenobarbitone sodium ................177 Phenoxybenzamine hydrochloride ............................. 47 Phenoxymethylpenicillin (Penicillin V) ............................... 82 Phentolamine mesylate ..................47 Phenylephrine hydrochloride ........................... 170 Phenytoin sodium .................121, 123 Phlexy 10 ......................................194 Phosphate-Sandoz .........................44 Phytomenadione .............................41 Pilocarpine ....................................169 Pimafucort ......................................60 Pindolol ...........................................51 Pinetarsol ........................................64 Pinorax ...........................................35 Pinorax Forte ..................................35 Pioglitazone ....................................31 Piportil ..........................................130 Pipothiazine palmitate ..................130 Pizaccord ........................................31 Pizotifen ........................................125 PKU Anamix Infant .......................194 PKU Lophlex LQ ...........................194 Plaquenil .........................................85 Plendil ER .......................................52 Podophyllotoxin ..............................65 Polaramine ....................................159 Poloxamer .......................................35 Poly-Tears .....................................169 Poly-Visc .......................................170 Polycal ..........................................180 Polyvinyl alcohol ...........................169 Ponstan ..........................................97 Postinor-1 .......................................69 Potassium bicarbonate ...................44 Potassium chloride ...................43–44 Potassium citrate ............................71 Potassium iodate ............................38 Povidone iodine ..............................62 Pradaxa ..........................................42 Pravachol ........................................45 Pravastatin ......................................45 Prazosin hydrochloride ...................47 Pred Forte ....................................167 Pred Mild ......................................167 Prednisolone acetate ....................167 Prednisolone sodium phosphate .................................. 73 Prednisone .....................................73 Prefrin ...........................................170 Pregnancy Tests - hCG Urine .........70 Pregnancy tests - HCG urine .........70 Premarin .........................................75 Premia 2.5 Continuous ...................75 Premia 5 Continuous ......................75 Prezista ...........................................92 Priadel ..........................................128 Primidone .....................................123 Primolut N .......................................76 Probenecid ...................................113 Probenecid-AFT ...........................113 Procaine penicillin ...........................82 Procarbazine hydrochloride ..........147 Prochlorperazine ..........................126 Proctosedyl .....................................28 Procyclidine hydrochloride ............115 Prodopa ..........................................53 Prograf ..........................................158 Progynova ......................................74 Promethazine hydrochloride .........160 Promethazine theoclate ................126 Promethazine Winthrop Elixir ......................................... 160 Promod .........................................182 Propafenone hydrochloride ............50 Propamidine isethionate ...............166 Propranolol .....................................51 Propylene glycol ...........................177 Protamine sulphate .........................42 Protaphane .....................................30 Protaphane Penﬁll ..........................30 Protifar ..........................................182 Provera .....................................75, 76 PSO ......................................198–201 Psoriasis and Eczema Preparations .............................. 62 Pulmicort Turbuhaler ....................160 Pulmocare ....................................183 Pulmozyme ...................................164 Purinethol .....................................144 Pyrazinamide ..................................85 Pyridostigmine bromide ..................97 PyridoxADE ....................................37 Pyridoxine hydrochloride ................37 Pytazen SR .....................................41 -QQ 200 ............................................113 Q 300 ............................................113 Questran-Lite ..................................45 Quetapel .......................................128

218

INDEX Generic Chemicals and Brands

Quetiapine ....................................128 Quinapril .........................................48 Quinapril with hydrochlorothiazide ................... 48 Quinine sulphate ...........................113 -RRA-Morph .....................................117 Raloxifene hydrochloride ..............109 Raltegravir potassium .....................92 Ranbaxy-Cefaclor ...........................79 Ranitidine hydrochloride .................29 Rapamune ....................................157 Redipred .........................................73 Regitine ..........................................47 Renilon 7.5 ...................................186 Resonium-A ....................................44 Resource Beneprotein ..................182 Resource Diabetic ........................183 Respigen ......................................162 Respiratory Devices .....................165 Respiratory Stimulants .................165 ReTrieve .........................................56 Retrovir ...........................................92 Rex Medical Genito-Urinary ............................70 Infection ......................................82 Rexacrom .....................................167 Reyataz ..........................................92 Ridal .............................................129 Ridaura ...........................................98 Rifabutin .........................................85 Rifadin ............................................86 Rifampicin .......................................86 Riﬁnah ............................................85 Riodine ...........................................62 Risperdal ......................................129 Risperdal Consta ..........................130 Risperdal Quicklet ........................131 Risperidone ..........................129–131 Risperon .......................................129 Ritalin ............................................136 Ritalin LA ......................................137 Ritalin SR ......................................136 Ritonavir .........................................92 Rituximab ......................................155 Rivacol ............................................36 Rivaroxaban ....................................42 Rivotril ...........................................121 Rizatriptan benzoate .....................125 Rocaltrol solution ............................37 Roferon-A .......................................94 Ropin ............................................114 Ropinirole hydrochloride ...............114 Roxithromycin .................................81 Rubifen .........................................136 Rubifen SR ...................................136 Rythmodan .....................................50 Rytmonorm .....................................50 -SS26LBW Gold RTF .......................194 Sabril ............................................124 Salamol .........................................162 Salapin ..........................................162 Salazopyrin .....................................27 Salazopyrin EN ...............................27 Salbutamol ....................................162 Salbutamol with ipratropium bromide .................................... 163 Salicylic acid ...................................64 Salmeterol ....................................161 Sandomigran ................................125 Sandostatin ...................................152 Sandostatin LAR ...........................152 SC Proﬁ-Fine ..................................33 Scalp Preparations .........................64 Scopoderm TTS ...........................125 Sebizole ..........................................64 Sedatives and Hypnotics ..............134 Selegiline hydrochloride ...............114 Senna .............................................35 Senokot ..........................................35 SensoCard ......................................32 Serenace ......................................128 Seretide ........................................162 Seretide Accuhaler .......................162 Serevent .......................................161 Serevent Accuhaler ......................161 Serophene ......................................78 Seroquel .......................................128 Sertraline ......................................120 Sevredol .......................................117 Sex Hormones Non Contraceptive ............................ 73 Shield 49 .........................................66 Shield Blue .....................................66 Shield XL ........................................66 Sildenaﬁl .........................................55 Silver sulphadiazine ........................57 Simethicone ....................................26 Simvastatin .....................................45 Sindopa ........................................114 Sinemet ........................................114 Sinemet CR ..................................114 Sirolimus .......................................157 Siterone ..........................................73 Slow-Lopresor ................................51 Sodibic ............................................44 Sodium acid phosphate ..................35 Sodium alginate ..............................26 Sodium aurothiomalate ...................98 Sodium bicarbonate Blood ....................................43–44 Extemporaneous ......................177 Sodium calcium edetate .................39 Sodium carboxymethylcellulose .............. 36 Sodium chloride Blood ..........................................43 Respiratory ...............................164 Sodium citrate with sodium lauryl sulphoacetate ............................ 35 Sodium citro-tartrate .......................71 Sodium cromoglycate Alimentary ..................................27 Respiratory .......................163–164 Sensory ....................................167 Sodium ﬂuoride ..............................38 Sodium nitroprusside ......................31 Sodium polystyrene sulphonate ................................. 44 Sodium tetradecyl sulphate ............41 Sodium valproate ..........................124 Sofradex .......................................166 Soframycin ....................................166 Solian ............................................127 Solifenacin succinate ......................71 Solox ...............................................29 Solu-Cortef .....................................72 Solu-Medrol ....................................72 Somatropin .....................................77 Sotacor ...........................................51 Sotalol .............................................51 Space Chamber ............................165 Space Chamber Plus ....................165 Spacer device ...............................165 Spacer device autoclavable ..........165 Span-K ............................................44 Spiriva ...........................................163 Spironolactone ................................53 Spirotone ........................................53 Sprycel .........................................149 Stavudine [d4T] ..............................92 Stelazine .......................................129 Stemetil .........................................126 Stesolid .........................................121 Stimulants/ADHD Treatments ............................... 135 Stocrin ............................................91

219

INDEX Generic Chemicals and Brands

Stomahesive ...................................36 Strattera ........................................135 Sucralfate .......................................29 Sulindac ..........................................98 Sulphasalazine ...............................27 Sulphur ...........................................64 Sumatriptan ..................................125 Sunitinib ........................................151 Sunscreens .....................................64 Sunscreens, proprietary .................64 Suplena ........................................187 Surgam ...........................................98 Sustagen Hospital Formula ..........190 Sustanon Ampoules .......................73 Sutent ...........................................151 Symbicort Turbuhaler 100/6 .........162 Symbicort Turbuhaler 200/6 .........162 Symbicort Turbuhaler 400/12 ..................................... 162 Symmetrel ....................................114 Sympathomimetics .........................54 Synacthen .......................................73 Synacthen Depot ............................73 Synermox .......................................81 Synthroid ........................................76 Syntocinon ......................................70 Syntometrine ..................................70 Syrup (pharmaceutical grade) ...................................... 177 -TTacrolimus ....................................158 Tambocor ........................................50 Tambocor CR ..................................50 Tamoxifen citrate ...........................153 Tamsulosin hydrochloride ...............70 Tamsulosin-Rex ..............................70 Tap water ......................................177 Tar with triethanolamine lauryl sulphate and ﬂuorescein ............ 64 Tarceva .........................................150 Tasmar ..........................................114 Taxotere ........................................146 Tegretol .........................................121 Tegretol CR ...................................121 Telfast ...........................................159 Temazepam ..................................134 Temodal ........................................148 Temozolomide ..............................148 Tenofovir disoproxil fumarate ..........88 Tenoxicam ......................................98 Terazosin hydrochloride ..................47 Terbinaﬁne ......................................85 Terbutaline sulphate .....................162 Teriparatide ...................................110 Testosterone ...................................73 Testosterone cypionate ...................73 Testosterone esters ........................73 Testosterone undecanoate .............73 Tetrabenazine ...............................115 Tetrabromophenol ...........................71 Tetracosactrin .................................73 Teva ..............................................145 Thalidomide ..................................148 Thalomid .......................................148 Theophylline .................................164 Thiamine hydrochloride ..................37 Thioguanine ..................................144 Thiotepa ........................................141 Thymol glycerin ..............................36 Thyroid and Antithyroid Agents ....................................... 76 Tiaprofenic acid ..............................98 Tiberal .............................................85 Tilade ............................................163 Tilcotil .............................................98 Timolol maleate Cardiovascular ...........................51 Sensory ....................................167 Timoptol XE ..................................167 Tiotropium bromide .......................163 Titralac ............................................26 TMP ................................................84 Tobramycin Infection ......................................84 Sensory ....................................167 Tobrex ...........................................167 Tofranil ..........................................119 Tolcapone .....................................114 Tolvon ...........................................119 Topamax .......................................124 Topiramate ....................................124 Total parenteral nutrition (TPN) ......................................... 44 TPN ................................................44 Tracleer ...........................................55 Tramadol hydrochloride ................116 Trandate ..........................................51 Trandolapril .....................................48 Tranexamic acid ..............................41 Tranylcypromine sulphate .............119 Trastuzumab .................................156 Travatan ........................................168 Travoprost .....................................168 Treatments for Dementia ..............138 Treatments for Opioid Overdose ................................. 138 Treatments for Substance Dependence ............................ 138 Trental 400 ......................................54 Tretinoin Dermatological ...........................56 Oncology ..................................148 Triamcinolone acetonide Alimentary ..................................36 Dermatological ...........................60 Hormone ....................................73 Triamcinolone acetonide with gramicidin, neomycin and nystatin Dermatological ...........................60 Sensory ....................................166 Triazolam ......................................134 Trichozole .......................................85 Triclosan .........................................61 Triﬂuoperazine hydrochloride ........................... 129 Trimeprazine tartrate ....................160 Trimethoprim ...................................84 Trisequens ......................................75 Trisul ...............................................83 Trophic Hormones ..........................77 Tropicamide ..................................169 Tropisetron ....................................126 Trusopt ..........................................168 Two Cal HN ...................................191 Tyloxapol .......................................169 -UUltraproct ........................................28 Univent .................................163, 164 Ural .................................................71 Urea ................................................61 Urex Forte .......................................53 Urinary Agents ................................70 Urinary Tract Infections ...................95 Uromitexan ...................................147 Ursodeoxycholic acid ......................34 -VVaccines .........................................96 Valaciclovir ......................................88 Vallergan Forte .............................160 Valtrex .............................................88 Vancomycin hydrochloride ..............84 Vannair .........................................162 Varenicline tartrate .......................139 Vasodilators ....................................54 Vasopressin Agonists .....................77 Velcade .........................................145 Venlafaxine ...................................120

220

INDEX Generic Chemicals and Brands

Ventavis ..........................................55 Ventolin .........................................162 Vepesid .........................................147 Veracol ............................................79 Verapamil hydrochloride .................53 Vergo 16 .......................................125 Vermox ...........................................79 Verpamil SR ...................................53 Vesanoid .......................................148 Vesicare ..........................................71 Viaderm KC ....................................60 Viagra .............................................55 Vicrom ..........................................163 Videx EC .........................................91 Vigabatrin .....................................124 Vimpat ..........................................122 Vinblastine sulphate .....................148 Vincristine sulphate ......................148 Vinorelbine ....................................148 Vinorelbine Ebewe ........................148 Viramune ........................................91 Viramune Suspension ....................91 Viread .............................................88 Vistil ..............................................169 Vistil Forte ....................................169 Vitabdeck ........................................38 Vitadol C .........................................37 Vital HN ........................................186 Vitala-C ...........................................37 Vitamin A with vitamins D and C ................................................ 37 Vitamin B complex ..........................37 Vitamins ....................................37–38 Vivonex Pediatric ..........................195 Vivonex TEN .................................187 Volibris ............................................55 Voltaren ..........................................97 Voltaren D .......................................97 Voltaren Ophtha ............................167 Volumatic ......................................165 Vosol .............................................166 Vytorin ............................................46 -WWarfarin sodium ..............................43 Wart Preparations ...........................64 Wasp venom allergy treatment ................................. 159 Water Blood ..........................................44 Extemporaneous ......................177 Wool fat with mineral oil ..................61 -XXarelto ............................................42 Xeloda ..........................................141 Xenazine 25 ..................................115 XMET Maxamum ..........................193 XP Maxamaid ...............................194 XP Maxamum ...............................194 Xylocaine ......................................115 Xylocaine Viscous ........................115 -ZZantac .............................................29 Zapril ..............................................47 Zarontin ........................................122 Zavedos ........................................147 Zefﬁx ...............................................87 Zeldox ...........................................129 Zerit ................................................92 Zetop ............................................159 Ziagen .............................................91 Zidovudine [AZT] ............................92 Zidovudine [AZT] with lamivudine ................................. 92 Zinacef ............................................79 Zinc and castor oil ..........................61 Zinc sulphate ..................................39 Zincaps ...........................................39 Zinnat ..............................................79 Ziprasidone ...................................129 Zoladex ...........................................77 Zoledronic acid .............................111 Zopiclone ......................................134 Zostrix HP .......................................65 Zovirax ..........................................166 Zuclopenthixol decanoate .............131 Zuclopenthixol hydrochloride ........................... 129 Zyban ............................................138 Zyprexa .........................................128 Zyprexa Relprevv ..........................130 Zyprexa Zydis ...............................131

221

Pharmaceutical Management Agency Level 9, 40 Mercer Street, PO Box 10-254, Wellington 6143, New Zealand Phone: 64 4 460 4990 - Fax: 64 4 460 4995 - www.pharmac.govt.nz Freephone Information line (9am-5pm weekdays) 0800 66 00 50 ISSN 1172-9376 (Print) ISSN 1179-3686 (Online)

PHARMAC is the Government agency responsible for deciding which medicines are subsidised for New Zealanders. It manages spending on pharmaceuticals for the District Health Boards, and ensures that a comprehensive list of medicines (the Pharmaceutical Schedule) is subsidised for New Zealanders.

Metadata

Title

Pharmaceutical Schedule - effective 1 December 2011

Abstract

Pharmaceutical Management Agency December 2011 New Zealand Pharmaceutical Schedule December 2011 Volume 18 Number 3 Editors: Kaye Wilson, Rebecca Bloor & Donna Jennings email: schedule@pharmac.govt.nz Telephone +64 4 460 4990 Facsimile +64 4 460 4995 Level 9, 40 Mercer Street…

Page 1

Note

This text has been extracted from the source PDF document.

Also available as plain text.

Please contact webmaster to discuss alternative format options.